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Dr Jennifer Keiser

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. d'Orchymont F, Hess J, Panic G, Jakubaszek M, Gemperle L, Keiser J, Gasser G. Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates. Medchemcomm. 2018 Nov 01; 9(11):1905-1909. PMID: 30568758.
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    2. Kovac J, Meister I, Neodo A, Panic G, Coulibaly JT, Falcoz C, Keiser J. Pharmacokinetics of Praziquantel in Schistosoma mansoni- and Schistosoma haematobium-Infected School- and Preschool-Aged Children. Antimicrob Agents Chemother. 2018 Aug; 62(8). PMID: 29866859.
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    3. Moser W, Schindler C, Keiser J. Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis. BMJ. 2017 Sep 25; 358:j4307. PMID: 28947636.
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    4. Moser W, Coulibaly JT, Ali SM, Ame SM, Amour AK, Yapi RB, Albonico M, Puchkov M, Huwyler J, Hattendorf J, Keiser J. Efficacy and safety of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel pamoate, and albendazole plus oxantel pamoate against hookworm and concomitant soil-transmitted helminth infections in Tanzania and Côte d'Ivoire: a randomised, controlled, single-blinded, non-inferiority trial. Lancet Infect Dis. 2017 11; 17(11):1162-1171. PMID: 28864027.
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    5. Coulibaly JT, Panic G, Silué KD, Kovac J, Hattendorf J, Keiser J. Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial. Lancet Glob Health. 2017 07; 5(7):e688-e698. PMID: 28619227.
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    6. Bergquist R, Utzinger J, Keiser J. Controlling schistosomiasis with praziquantel: How much longer without a viable alternative? Infect Dis Poverty. 2017 Mar 28; 6(1):74. PMID: 28351414.
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    7. Cowan N, Meier C, Neodo A, Keiser J. Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes. Int J Parasitol Drugs Drug Resist. 2017 08; 7(2):159-173. PMID: 28371660.
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    8. Moser W, Labhardt ND, Cheleboi M, Muhairwe J, Keiser J. Unexpected low soil-transmitted helminth prevalence in the Butha-Buthe district in Lesotho, results from a cross-sectional survey. Parasit Vectors. 2017 02 08; 10(1):72. PMID: 28179008.
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    9. Bogoch II, Coulibaly JT, Rajchgot J, Andrews JR, Kovac J, Utzinger J, Panic G, Keiser J. Poor Validity of Noninvasive Hemoglobin Measurements by Pulse Oximetry Compared with Conventional Absorptiometry in Children in Côte d'Ivoire. Am J Trop Med Hyg. 2017 Jan 11; 96(1):217-220. PMID: 28077748.
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    10. Cowan N, Raimondo A, Keiser J. Approved oncology drugs lack in vivo activity against Trichuris muris despite in vitro activity. Parasitol Res. 2016 Nov; 115(11):4443-4446. PMID: 27498843.
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    11. Sayasone S, Odermatt P, Vonghachack Y, Xayavong S, Senggnam K, Duthaler U, Akkhavong K, Hattendorf J, Keiser J. Efficacy and safety of tribendimidine against Opisthorchis viverrini: two randomised, parallel-group, single-blind, dose-ranging, phase 2 trials. Lancet Infect Dis. 2016 Oct; 16(10):1145-1153. PMID: 27472949.
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    12. Keiser J, Panic G, Adelfio R, Cowan N, Vargas M, Scandale I. Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections. Parasit Vectors. 2016 07 01; 9(1):376. PMID: 27363703.
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    13. Clède S, Cowan N, Lambert F, Bertrand HC, Rubbiani R, Patra M, Hess J, Sandt C, Trcera N, Gasser G, Keiser J, Policar C. Bimodal X-ray and Infrared Imaging of an Organometallic Derivative of Praziquantel in Schistosoma mansoni. Chembiochem. 2016 06 02; 17(11):1004-7. PMID: 26991635.
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    14. Speich B, Moser W, Ali SM, Ame SM, Albonico M, Hattendorf J, Keiser J. Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasit Vectors. 2016 Mar 02; 9:123. PMID: 26935065.
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    15. Panic G, Flores D, Ingram-Sieber K, Keiser J. Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays. Parasit Vectors. 2015 Dec 08; 8:624. PMID: 26644133.
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    16. Bogoch II, Sayasone S, Vonghachack Y, Meister I, Utzinger J, Odermatt P, Andrews JR, Keiser J. Diagnosis of Opisthorchis viverrini Infection with Handheld Microscopy in Lao People's Democratic Republic. Am J Trop Med Hyg. 2016 Jan; 94(1):158-60. PMID: 26526923.
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    17. Flores D, Panic G, Braissant O, Keiser J. A novel isothermal microcalorimetry tool to assess drug effects on Ancylostoma ceylanicum and Necator americanus. Appl Microbiol Biotechnol. 2016 Jan; 100(2):837-46. PMID: 26519051.
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    18. Meister I, Leonidova A, Kovac J, Duthaler U, Keiser J, Huwyler J. Development and validation of an enantioselective LC-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots. J Pharm Biomed Anal. 2016 Jan 25; 118:81-88. PMID: 26517852.
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    19. Keiser J. Is Caenorhabditis elegans the Magic Bullet for Anthelminthic Drug Discovery? Trends Parasitol. 2015 Oct; 31(10):455-456. PMID: 26422771.
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    20. Speich B, Croll D, Fürst T, Utzinger J, Keiser J. Effect of sanitation and water treatment on intestinal protozoa infection: a systematic review and meta-analysis. Lancet Infect Dis. 2016 Jan; 16(1):87-99. PMID: 26404667.
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    21. Moser W, Ali SM, Ame SM, Speich B, Puchkov M, Huwyler J, Albonico M, Hattendorf J, Keiser J. Efficacy and safety of oxantel pamoate in school-aged children infected with Trichuris trichiura on Pemba Island, Tanzania: a parallel, randomised, controlled, dose-ranging study. Lancet Infect Dis. 2016 Jan; 16(1):53-60. PMID: 26388169.
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    22. Cowan N, Keiser J. Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni. Parasit Vectors. 2015 Aug 13; 8:417. PMID: 26265386.
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    23. Panic G, Vargas M, Scandale I, Keiser J. Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni. PLoS Negl Trop Dis. 2015; 9(7):e0003962. PMID: 26230921.
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    24. Vejzagic N, Adelfio R, Keiser J, Kringel H, Thamsborg SM, Kapel CM. Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis. Parasit Vectors. 2015 Jul 15; 8:371. PMID: 26174801.
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    25. Olliaro PL, Vaillant M, Diawara A, Coulibaly JT, Garba A, Keiser J, King CH, Knopp S, Landouré A, N'Goran EK, Raso G, Scherrer AU, Sousa-Figueiredo JC, Stete K, Zhou XN, Utzinger J. Toward Measuring Schistosoma Response to Praziquantel Treatment with Appropriate Descriptors of Egg Excretion. PLoS Negl Trop Dis. 2015; 9(6):e0003821. PMID: 26086551.
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    26. Ephraim RK, Duah E, Cybulski JS, Prakash M, D'Ambrosio MV, Fletcher DA, Keiser J, Andrews JR, Bogoch II. Diagnosis of Schistosoma haematobium infection with a mobile phone-mounted Foldscope and a reversed-lens CellScope in Ghana. Am J Trop Med Hyg. 2015 Jun; 92(6):1253-6. PMID: 25918211.
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    27. Barda B, Albonico M, Ianniello D, Ame SM, Keiser J, Speich B, Rinaldi L, Cringoli G, Burioni R, Montresor A, Utzinger J. How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using Mini-FLOTAC? PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003698. PMID: 25848772.
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    28. Ogorodova LM, Fedorova OS, Sripa B, Mordvinov VA, Katokhin AV, Keiser J, Odermatt P, Brindley PJ, Mayboroda OA, Velavan TP, Freidin MB, Sazonov AE, Saltykova IV, Pakharukova MY, Kovshirina YV, Kaloulis K, Krylova OY, Yazdanbakhsh M. Opisthorchiasis: an overlooked danger. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003563. PMID: 25836334.
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    29. Braissant O, Keiser J, Meister I, Bachmann A, Wirz D, Göpfert B, Bonkat G, Wadsö I. Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay. Biotechnol J. 2015 Mar; 10(3):460-8. PMID: 25511812.
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    30. Keiser J, Panic G, Vargas M, Wang C, Dong Y, Gautam N, Vennerstrom JL. Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal. J Antimicrob Chemother. 2015; 70(6):1788-97. PMID: 25691324.
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    31. Cowan N, Yaremenko IA, Krylov IB, Terent'ev AO, Keiser J. Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni. Bioorg Med Chem. 2015 Aug 15; 23(16):5175-81. PMID: 25744189.
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    32. Speich B, Ali SM, Ame SM, Albonico M, Utzinger J, Keiser J. Quality control in the diagnosis of Trichuris trichiura and Ascaris lumbricoides using the Kato-Katz technique: experience from three randomised controlled trials. Parasit Vectors. 2015 Feb 05; 8:82. PMID: 25652120.
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    33. Cowan N, Dätwyler P, Ernst B, Wang C, Vennerstrom JL, Spangenberg T, Keiser J. Activities of N,N'-Diarylurea MMV665852 analogs against Schistosoma mansoni. Antimicrob Agents Chemother. 2015 Apr; 59(4):1935-41. PMID: 25583726.
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    34. Speich B, Ali SM, Ame SM, Bogoch II, Alles R, Huwyler J, Albonico M, Hattendorf J, Utzinger J, Keiser J. Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial. Lancet Infect Dis. 2015 Mar; 15(3):277-84. PMID: 25589326.
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    35. Hess J, Keiser J, Gasser G. Toward organometallic antischistosomal drug candidates. Future Med Chem. 2015; 7(6):821-30. PMID: 25996072.
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    36. Kulke D, von Samson-Himmelstjerna G, Miltsch SM, Wolstenholme AJ, Jex AR, Gasser RB, Ballesteros C, Geary TG, Keiser J, Townson S, Harder A, Krücken J. Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside. PLoS Negl Trop Dis. 2014 Dec; 8(12):e3401. PMID: 25521608.
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    37. Duthaler U, Keiser J, Huwyler J. LC-MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots. J Pharm Biomed Anal. 2015 Feb; 105:163-73. PMID: 25553533.
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    38. Bogoch II, Andrews JR, Speich B, Ame SM, Ali SM, Stothard JR, Utzinger J, Keiser J. Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection. Am J Trop Med Hyg. 2014 Dec; 91(6):1138-41. PMID: 25246697.
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    39. Keiser J, Vargas M, Rubbiani R, Gasser G, Biot C. In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasit Vectors. 2014 Sep 04; 7:424. PMID: 25190030.
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    40. Panic G, Duthaler U, Speich B, Keiser J. Repurposing drugs for the treatment and control of helminth infections. Int J Parasitol Drugs Drug Resist. 2014 Dec; 4(3):185-200. PMID: 25516827.
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    41. Tritten L, Keiser J, Karwa T, Utzinger J, Holmes E, Saric J. Comparing systemic metabolic responses in mice to single or dual infection with Plasmodium berghei and Heligmosomoides bakeri. Mol Biosyst. 2014 Jul 29; 10(9):2358-67. PMID: 24960299.
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    42. Hotez PJ, Alvarado M, Basáñez MG, Bolliger I, Bourne R, Boussinesq M, Brooker SJ, Brown AS, Buckle G, Budke CM, Carabin H, Coffeng LE, Fèvre EM, Fürst T, Halasa YA, Jasrasaria R, Johns NE, Keiser J, King CH, Lozano R, Murdoch ME, O'Hanlon S, Pion SD, Pullan RL, Ramaiah KD, Roberts T, Shepard DS, Smith JL, Stolk WA, Undurraga EA, Utzinger J, Wang M, Murray CJ, Naghavi M. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl Trop Dis. 2014 Jul; 8(7):e2865. PMID: 25058013.
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    43. Spivak AY, Keiser J, Vargas M, Gubaidullin RR, Nedopekina DA, Shakurova ER, Khalitova RR, Odinokov VN. Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo. Bioorg Med Chem. 2014 Nov 01; 22(21):6297-304. PMID: 25245671.
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    44. Keiser J, Silué KD, Adiossan LK, N'Guessan NA, Monsan N, Utzinger J, N'Goran EK. Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial. PLoS Negl Trop Dis. 2014 Jul; 8(7):e2975. PMID: 25033291.
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    45. Meister I, Ingram-Sieber K, Cowan N, Todd M, Robertson MN, Meli C, Patra M, Gasser G, Keiser J. Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni. Antimicrob Agents Chemother. 2014 Sep; 58(9):5466-72. PMID: 24982093.
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    46. Keiser J, Speich B, Utzinger J. Oxantel pamoate-albendazole for Trichuris trichiura infection. N Engl J Med. 2014 05 15; 370(20):1953-4. PMID: 24827042.
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    47. Bogoch II, Coulibaly JT, Andrews JR, Speich B, Keiser J, Stothard JR, N'goran EK, Utzinger J. Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection. Parasitology. 2014 Dec; 141(14):1811-8. PMID: 24776232.
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    48. Wang C, Zhao Q, Min J, Muniyan S, Vargas M, Wang X, Dong Y, Guy RK, Lin MF, Keiser J, Vennerstrom JL. Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978. Am J Trop Med Hyg. 2014 Jun; 90(6):1156-8. PMID: 24686741.
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    49. Speich B, Ame SM, Ali SM, Alles R, Huwyler J, Hattendorf J, Utzinger J, Albonico M, Keiser J. Oxantel pamoate-albendazole for Trichuris trichiura infection. N Engl J Med. 2014 Feb 13; 370(7):610-20. PMID: 24521107.
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    50. Ingram-Sieber K, Cowan N, Panic G, Vargas M, Mansour NR, Bickle QD, Wells TN, Spangenberg T, Keiser J. Orally active antischistosomal early leads identified from the open access malaria box. PLoS Negl Trop Dis. 2014; 8(1):e2610. PMID: 24416463.
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    51. Olliaro P, Delgado-Romero P, Keiser J. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer). J Antimicrob Chemother. 2014 Apr; 69(4):863-70. PMID: 24390933.
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    52. Utzinger J, Keiser J. Research and development for neglected diseases: more is still needed, and faster. Lancet Glob Health. 2013 Dec; 1(6):e317-8. PMID: 25104587.
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    53. Patra M, Ingram K, Leonidova A, Pierroz V, Ferrari S, Robertson MN, Todd MH, Keiser J, Gasser G. In vitro metabolic profile and in vivo antischistosomal activity studies of (?(6)-praziquantel)Cr(CO)3 derivatives. J Med Chem. 2013 Nov 27; 56(22):9192-8. PMID: 24219617.
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    54. Qian MB, Yap P, Yang YC, Liang H, Jiang ZH, Li W, Utzinger J, Zhou XN, Keiser J. Accuracy of the Kato-Katz method and formalin-ether concentration technique for the diagnosis of Clonorchis sinensis, and implication for assessing drug efficacy. Parasit Vectors. 2013 Oct 29; 6(1):314. PMID: 24499644.
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    55. Küster T, Kriegel N, Stadelmann B, Wang X, Dong Y, Vennerstrom JL, Keiser J, Hemphill A. Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes. Int J Antimicrob Agents. 2014 Jan; 43(1):40-6. PMID: 24239405.
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    56. Knopp S, Becker SL, Ingram KJ, Keiser J, Utzinger J. Diagnosis and treatment of schistosomiasis in children in the era of intensified control. Expert Rev Anti Infect Ther. 2013 Nov; 11(11):1237-58. PMID: 24127662.
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    57. Patra M, Joshi T, Pierroz V, Ingram K, Kaiser M, Ferrari S, Spingler B, Keiser J, Gasser G. DMSO-mediated ligand dissociation: renaissance for biological activity of N-heterocyclic-[Ru(?6-arene)Cl2] drug candidates. Chemistry. 2013 Oct 25; 19(44):14768-72. PMID: 24123460.
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    58. Tritten L, Keiser J, Godejohann M, Utzinger J, Vargas M, Beckonert O, Holmes E, Saric J. Metabolic profiling framework for discovery of candidate diagnostic markers of malaria. Sci Rep. 2013 Sep 26; 3:2769. PMID: 24067624.
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    59. Meister I, Duthaler U, Huwyler J, Rinaldi L, Bosco A, Cringoli G, Keiser J. Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep. Vet Parasitol. 2013 Nov 15; 198(1-2):102-10. PMID: 24011678.
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    60. Panic G, Ingram K, Keiser J. Development of an in vitro drug sensitivity assay based on newly excysted larvae of Echinostoma caproni. Parasit Vectors. 2013 Aug 13; 6:237. PMID: 23941505.
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    61. Ingram K, Duthaler U, Vargas M, Ellis W, Keiser J. Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection. Antimicrob Agents Chemother. 2013 Sep; 57(9):4506-11. PMID: 23836173.
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    62. Tsang AS, Ingram K, Keiser J, Hibbert DB, Todd MH. Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group. Org Biomol Chem. 2013 Aug 14; 11(30):4921-4. PMID: 23820826.
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    63. Keiser J, Tritten L, Silbereisen A, Speich B, Adelfio R, Vargas M. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013; 7(3):e2119. PMID: 23556013.
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    64. Bogoch II, Andrews JR, Speich B, Utzinger J, Ame SM, Ali SM, Keiser J. Mobile phone microscopy for the diagnosis of soil-transmitted helminth infections: a proof-of-concept study. Am J Trop Med Hyg. 2013 Apr; 88(4):626-9. PMID: 23478580.
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    65. Wimmersberger D, Tritten L, Keiser J. Development of an in vitro drug sensitivity assay for Trichuris muris first-stage larvae. Parasit Vectors. 2013 Feb 22; 6:42. PMID: 23433224.
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    66. Xiao SH, Utzinger J, Tanner M, Keiser J, Xue J. Advances with the Chinese anthelminthic drug tribendimidine in clinical trials and laboratory investigations. Acta Trop. 2013 May; 126(2):115-26. PMID: 23352956.
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    67. Patra M, Ingram K, Pierroz V, Ferrari S, Spingler B, Gasser RB, Keiser J, Gasser G. [(?(6)-Praziquantel)Cr(CO)3] derivatives with remarkable in vitro anti-schistosomal activity. Chemistry. 2013 Feb 11; 19(7):2232-5. PMID: 23296750.
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    68. Speich B, Marti H, Ame SM, Ali SM, Bogoch II, Utzinger J, Albonico M, Keiser J. Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. Parasit Vectors. 2013 Jan 04; 6:3. PMID: 23289920.
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    69. Keiser J, Tritten L, Adelfio R, Vargas M. Effect of combinations of marketed human anthelmintic drugs against Trichuris muris in vitro and in vivo. Parasit Vectors. 2012 Dec 11; 5:292. PMID: 23231753.
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    70. Qian MB, Yap P, Yang YC, Liang H, Jiang ZH, Li W, Tan YG, Zhou H, Utzinger J, Zhou XN, Keiser J. Efficacy and safety of tribendimidine against Clonorchis sinensis. Clin Infect Dis. 2013 Apr; 56(7):e76-82. PMID: 23223597.
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    71. Coulibaly JT, N'gbesso YK, Knopp S, Keiser J, N'Goran EK, Utzinger J. Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium. PLoS Negl Trop Dis. 2012; 6(12):e1917. PMID: 23236526.
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    72. Keiser J, Manneck T, Kirchhofer C, Braissant O. Isothermal microcalorimetry to study the activity of triclabendazole and its metabolites on juvenile and adult Fasciola hepatica. Exp Parasitol. 2013 Mar; 133(3):265-8. PMID: 23206957.
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    73. Utzinger J, Becker SL, Knopp S, Blum J, Neumayr AL, Keiser J, Hatz CF. Neglected tropical diseases: diagnosis, clinical management, treatment and control. Swiss Med Wkly. 2012; 142:w13727. PMID: 23180107.
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    74. Toyang NJ, Ateh EN, Keiser J, Vargas M, Bach H, Tane P, Sondengam LB, Davis H, Bryant J, Verpoorte R. Toxicity, antimicrobial and anthelmintic activities of Vernonia guineensis Benth. (Asteraceae) crude extracts. J Ethnopharmacol. 2012 Dec 18; 144(3):700-4. PMID: 23107821.
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    75. Ingram K, Yaremenko IA, Krylov IB, Hofer L, Terent'ev AO, Keiser J. Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides. J Med Chem. 2012 Oct 25; 55(20):8700-11. PMID: 23013253.
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    76. Patra M, Ingram K, Pierroz V, Ferrari S, Spingler B, Keiser J, Gasser G. Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis, and biological evaluation. J Med Chem. 2012 Oct 25; 55(20):8790-8. PMID: 23005702.
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    77. Keiser J, Adelfio R, Vargas M, Odermatt P, Tesana S. Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo. J Helminthol. 2013 Jun; 87(2):252-6. PMID: 22892101.
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    78. Saric J, Want EJ, Duthaler U, Lewis M, Keiser J, Shockcor JP, Ross GA, Nicholson JK, Holmes E, Tavares MF. Systematic evaluation of extraction methods for multiplatform-based metabotyping: application to the Fasciola hepatica metabolome. Anal Chem. 2012 Aug 21; 84(16):6963-72. PMID: 22799605.
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    79. Marxer M, Ingram K, Keiser J. Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula. Parasit Vectors. 2012 Aug 09; 5:165. PMID: 22876861.
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    80. Lovis L, Mak TK, Phongluxa K, Ayé Soukhathammavong P, Vonghachack Y, Keiser J, Vounatsou P, Tanner M, Hatz C, Utzinger J, Odermatt P, Akkhavong K. Efficacy of praziquantel against Schistosoma mekongi and Opisthorchis viverrini: a randomized, single-blinded dose-comparison trial. PLoS Negl Trop Dis. 2012; 6(7):e1726. PMID: 22848766.
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    81. Fürst T, Sayasone S, Odermatt P, Keiser J, Utzinger J. Manifestation, diagnosis, and management of foodborne trematodiasis. BMJ. 2012 Jun 26; 344:e4093. PMID: 22736467.
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    82. Speich B, Ame SM, Ali SM, Alles R, Hattendorf J, Utzinger J, Albonico M, Keiser J. Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial. PLoS Negl Trop Dis. 2012; 6(6):e1685. PMID: 22679525.
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    176. Keiser J, Shu-Hua X, Utzinger J. Effect of tribendimidine on adult Echinostoma caproni harbored in mice, including scanning electron microscopic observations. J Parasitol. 2006 Aug; 92(4):858-62. PMID: 16995405.
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    177. Keiser J, El Ela NA, El Komy E, El Lakkany N, Diab T, Chollet J, Utzinger J, Barakat R. Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model. Am J Trop Med Hyg. 2006 Aug; 75(2):287-91. PMID: 16896134.
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    178. Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect Dis. 2006 Jul; 6(7):411-25. PMID: 16790382.
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    179. Keiser J, Shu-Hua X, Tanner M, Utzinger J. Artesunate and artemether are effective fasciolicides in the rat model and in vitro. J Antimicrob Chemother. 2006 Jun; 57(6):1139-45. PMID: 16581915.
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    180. Keiser J, Brun R, Fried B, Utzinger J. Trematocidal activity of praziquantel and artemisinin derivatives: in vitro and in vivo investigations with adult Echinostoma caproni. Antimicrob Agents Chemother. 2006 Feb; 50(2):803-5. PMID: 16436751.
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    181. Keiser J, Engels D, Büscher G, Utzinger J. Triclabendazole for the treatment of fascioliasis and paragonimiasis. Expert Opin Investig Drugs. 2005 Dec; 14(12):1513-26. PMID: 16307491.
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    182. Keiser J, Singer BH, Utzinger J. Reducing the burden of malaria in different eco-epidemiological settings with environmental management: a systematic review. Lancet Infect Dis. 2005 Nov; 5(11):695-708. PMID: 16253887.
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    183. Keiser J, Utzinger J. Emerging foodborne trematodiasis. Emerg Infect Dis. 2005 Oct; 11(10):1507-14. PMID: 16318688.
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    184. Erlanger TE, Keiser J, Caldas De Castro M, Bos R, Singer BH, Tanner M, Utzinger J. Effect of water resource development and management on lymphatic filariasis, and estimates of populations at risk. Am J Trop Med Hyg. 2005 Sep; 73(3):523-33. PMID: 16172476.
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    185. Keiser J, Maltese MF, Erlanger TE, Bos R, Tanner M, Singer BH, Utzinger J. Effect of irrigated rice agriculture on Japanese encephalitis, including challenges and opportunities for integrated vector management. Acta Trop. 2005 Jul; 95(1):40-57. PMID: 15878762.
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    186. Keiser J, De Castro MC, Maltese MF, Bos R, Tanner M, Singer BH, Utzinger J. Effect of irrigation and large dams on the burden of malaria on a global and regional scale. Am J Trop Med Hyg. 2005 Apr; 72(4):392-406. PMID: 15827275.
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    187. Caldas de Castro M, Yamagata Y, Mtasiwa D, Tanner M, Utzinger J, Keiser J, Singer BH. Integrated urban malaria control: a case study in dar es salaam, Tanzania. Am J Trop Med Hyg. 2004 Aug; 71(2 Suppl):103-17. PMID: 15331826.
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    188. Keiser J, Utzinger J. Chemotherapy for major food-borne trematodes: a review. Expert Opin Pharmacother. 2004 Aug; 5(8):1711-26. PMID: 15264986.
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    189. Keiser J, Utzinger J, Caldas de Castro M, Smith TA, Tanner M, Singer BH. Urbanization in sub-saharan Africa and implication for malaria control. Am J Trop Med Hyg. 2004 Aug; 71(2 Suppl):118-27. PMID: 15331827.
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    190. Keiser J, Utzinger J, Tanner M, Singer BH. Representation of authors and editors from countries with different human development indexes in the leading literature on tropical medicine: survey of current evidence. BMJ. 2004 May 22; 328(7450):1229-32. PMID: 15059851.
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    191. Utzinger J, Keiser J. Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control. Expert Opin Pharmacother. 2004 Feb; 5(2):263-85. PMID: 14996624.
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    192. Girardin O, Dao D, Koudou BG, Essé C, Cissé G, Yao T, N'Goran EK, Tschannen AB, Bordmann G, Lehmann B, Nsabimana C, Keiser J, Killeen GF, Singer BH, Tanner M, Utzinger J. Opportunities and limiting factors of intensive vegetable farming in malaria endemic Côte d'Ivoire. Acta Trop. 2004 Jan; 89(2):109-23. PMID: 14732234.
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    193. Keiser J, Utzinger J, Singer BH. Gender composition of editorial boards of general medical journals. Lancet. 2003 Oct 18; 362(9392):1336. PMID: 14576002.
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    194. Utzinger J, Keiser J, Shuhua X, Tanner M, Singer BH. Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials. Antimicrob Agents Chemother. 2003 May; 47(5):1487-95. PMID: 12709312.
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    195. Keiser J, Utzinger J, Singer BH. The potential of intermittent irrigation for increasing rice yields, lowering water consumption, reducing methane emissions, and controlling malaria in African rice fields. J Am Mosq Control Assoc. 2002 Dec; 18(4):329-40. PMID: 12542191.
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    196. Keiser J, N'Goran EK, Singer BH, Lengeler C, Tanner M, Utzinger J. Association between Schistosoma mansoni and hookworm infections among schoolchildren in Côte d'Ivoire. Acta Trop. 2002 Oct; 84(1):31-41. PMID: 12387908.
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    197. Keiser J, N'Goran EK, Traoré M, Lohourignon KL, Singer BH, Lengeler C, Tanner M, Utzinger J. Polyparasitism with Schistosoma mansoni, geohelminths, and intestinal protozoa in rural Côte d'Ivoire. J Parasitol. 2002 Jun; 88(3):461-6. PMID: 12099412.
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    198. Patt WC, Edmunds JJ, Repine JT, Berryman KA, Reisdorph BR, Lee C, Plummer MS, Shahripour A, Haleen SJ, Keiser JA, Flynn MA, Welch KM, Reynolds EE, Rubin R, Tobias B, Hallak H, Doherty AM. Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists. J Med Chem. 1997 Mar 28; 40(7):1063-74. PMID: 9089328.
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    199. Reynolds EE, Keiser JA, Haleen SJ, Walker DM, Olszewski B, Schroeder RL, Taylor DG, Hwang O, Welch KM, Flynn MA, et al. Pharmacological characterization of PD 156707, an orally active ETA receptor antagonist. J Pharmacol Exp Ther. 1995 Jun; 273(3):1410-7. PMID: 7791115.
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    200. Doherty AM, Patt WC, Repine J, Edmunds JJ, Berryman KA, Reisdorph BR, Walker DM, Haleen SJ, Keiser JA, Flynn MA, et al. Structure-activity relationships of a novel series of orally active nonpeptide ETA and ETA/B endothelin receptor-selective antagonists. J Cardiovasc Pharmacol. 1995; 26 Suppl 3:S358-61. PMID: 8587414.
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