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Professor Joseph Mathu Ndung'u

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Derda R, Gitaka J, Klapperich CM, Mace CR, Kumar AA, Lieberman M, Linnes JC, Jores J, Nasimolo J, Ndung'u J, Taracha E, Weaver A, Weibel DB, Kariuki TM, Yager P. Enabling the Development and Deployment of Next Generation Point-of-Care Diagnostics. PLoS Negl Trop Dis. 2015 May; 9(5):e0003676. PMID: 25973602.
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    2. Sternberg JM, Gierlinski M, Biéler S, Ferguson MA, Ndung'u JM. Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis. PLoS Negl Trop Dis. 2014 Dec; 8(12):e3373. PMID: 25521120.
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    3. Murilla GA, Ndung'u K, Thuita JK, Gitonga PK, Kahiga DT, Auma JE, Ouma JO, Rutto JJ, Ndung'u JM. Kenya Trypanosomiasis Research Institute cryobank for human and animal trypanosome isolates to support research: opportunities and challenges. PLoS Negl Trop Dis. 2014 May; 8(5):e2747. PMID: 24853062.
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    4. Tiberti N, Lejon V, Hainard A, Courtioux B, Robin X, Turck N, Kristensson K, Matovu E, Enyaru JC, Mumba Ngoyi D, Krishna S, Bisser S, Ndung'u JM, Büscher P, Sanchez JC. Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness. PLoS Negl Trop Dis. 2013; 7(2):e2088. PMID: 23469311.
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    5. Dancet EA, Brännström M, Brasky K, Chai D, Chan AW, Conn PM, Else J, Falconer H, Fazleabas AT, Farah IO, Goddeeris BM, Golos TG, Hau J, Hearn JP, Kariuki TM, Kyama CM, Lebovic DI, Mwenda JM, Ndung'u J, Nyachieo A, Parker J, Slayden OD, Stouffer RL, Strauss JF, Taylor HS, Vanderpoel S, Westergaard JG, Zelinski M, D'Hooghe TM. The role of scientists and clinicians in raising public support for animal research in reproductive biology and medicine. Biol Reprod. 2013 Feb; 88(2):33. PMID: 23255340.
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    6. Tiberti N, Matovu E, Hainard A, Enyaru JC, Lejon V, Robin X, Turck N, Ngoyi DM, Krishna S, Bisser S, Courtioux B, Büscher P, Kristensson K, Ndung'u JM, Sanchez JC. New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients. Clin Transl Med. 2013 Jan 07; 2(1):1. PMID: 23369533.
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    7. Tiberti N, Hainard A, Lejon V, Courtioux B, Matovu E, Enyaru JC, Robin X, Turck N, Kristensson K, Ngoyi DM, Vatunga GM, Krishna S, Büscher P, Bisser S, Ndung'u JM, Sanchez JC. Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness. PLoS One. 2012; 7(7):e40909. PMID: 22815865.
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    8. Biéler S, Matovu E, Mitashi P, Ssewannyana E, Bi Shamamba SK, Bessell PR, Ndung'u JM. Improved detection of Trypanosoma brucei by lysis of red blood cells, concentration and LED fluorescence microscopy. Acta Trop. 2012 Feb; 121(2):135-40. PMID: 22079374.
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    9. Hainard A, Tiberti N, Robin X, Ngoyi DM, Matovu E, Enyaru JC, Müller M, Turck N, Ndung'u JM, Lejon V, Sanchez JC. Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis. Trop Med Int Health. 2011 Jan; 16(1):119-26. PMID: 20958893.
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    10. Tiberti N, Hainard A, Lejon V, Robin X, Ngoyi DM, Turck N, Matovu E, Enyaru J, Ndung'u JM, Scherl A, Dayon L, Sanchez JC. Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis. Mol Cell Proteomics. 2010 Dec; 9(12):2783-95. PMID: 20724469.
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    11. Ndung'u JM, Bieler S, Roscigno G. "Piggy-backing" on diagnostic platforms brings hope to neglected diseases: the case of sleeping sickness. PLoS Negl Trop Dis. 2010 May 25; 4(5):e715. PMID: 20520801.
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    12. Molyneux D, Ndung'u J, Maudlin I. Controlling sleeping sickness--"when will they ever learn?". PLoS Negl Trop Dis. 2010 May 25; 4(5):e609. PMID: 20520799.
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    13. Gray SA, Weigel KM, Miller KD, Ndung'u J, Büscher P, Tran T, Baird C, Cangelosi GA. Flow cytometry-based methods for assessing soluble scFv activities and detecting antigens in solution. Biotechnol Bioeng. 2010 Apr 01; 105(5):973-81. PMID: 19953671.
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    14. Gibson W, Nemetschke L, Ndung'u J. Conserved sequence of the TgsGP gene in Group 1 Trypanosoma brucei gambiense. Infect Genet Evol. 2010 May; 10(4):453-8. PMID: 20302972.
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    15. Maichomo MW, Kosura WO, Gathuma JM, Gitau GK, Ndung'u JM, Nyamwaro SO. Economic assessment of the performance of trypanotolerant cattle breeds in a pastoral production system in Kenya. J S Afr Vet Assoc. 2009 Sep; 80(3):157-62. PMID: 20169748.
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    16. Hainard A, Tiberti N, Robin X, Lejon V, Ngoyi DM, Matovu E, Enyaru JC, Fouda C, Ndung'u JM, Lisacek F, Müller M, Turck N, Sanchez JC. A combined CXCL10, CXCL8 and H-FABP panel for the staging of human African trypanosomiasis patients. PLoS Negl Trop Dis. 2009 Jun 16; 3(6):e459. PMID: 19554086.
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    17. Mdachi RE, Thuita JK, Kagira JM, Ngotho JM, Murilla GA, Ndung'u JM, Tidwell RR, Hall JE, Brun R. Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration. Antimicrob Agents Chemother. 2009 Mar; 53(3):953-7. PMID: 19064893.
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    18. Njiru ZK, Mikosza AS, Armstrong T, Enyaru JC, Ndung'u JM, Thompson AR. Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense. PLoS Negl Trop Dis. 2008 Feb 06; 2(1):e147. PMID: 18253475.
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    19. Njiru ZK, Mikosza AS, Matovu E, Enyaru JC, Ouma JO, Kibona SN, Thompson RC, Ndung'u JM. African trypanosomiasis: sensitive and rapid detection of the sub-genus Trypanozoon by loop-mediated isothermal amplification (LAMP) of parasite DNA. Int J Parasitol. 2008 Apr; 38(5):589-99. PMID: 17991469.
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    20. Maina NW, Oberle M, Otieno C, Kunz C, Maeser P, Ndung'u JM, Brun R. Isolation and propagation of Trypanosoma brucei gambiense from sleeping sickness patients in south Sudan. Trans R Soc Trop Med Hyg. 2007 Jun; 101(6):540-6. PMID: 17275053.
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    21. Kinyua JK, Nguu EK, Mulaa F, Ndung'u JM. Immunization of rabbits with Glossina pallidipes tsetse fly midgut proteins: effects on the fly and trypanosome transmission. Vaccine. 2005 May 31; 23(29):3824-8. PMID: 15893620.
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    22. Njiru ZK, Constantine CC, Ndung'u JM, Robertson I, Okaye S, Thompson RC, Reid SA. Detection of Trypanosoma evansi in camels using PCR and CATT/T. evansi tests in Kenya. Vet Parasitol. 2004 Oct 05; 124(3-4):187-99. PMID: 15381299.
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    23. Maina N, Ngotho JM, Were T, Thuita JK, Mwangangi DM, Kagira JM, Ndung'u JM, Sternberg J. Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops). Infect Immun. 2004 May; 72(5):3063-5. PMID: 15102822.
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    24. Masiga DK, Okech G, Irungu P, Ouma J, Wekesa S, Ouma B, Guya SO, Ndung'u JM. Growth and mortality in sheep and goats under high tsetse challenge in Kenya. Trop Anim Health Prod. 2002 Nov; 34(6):489-501. PMID: 12537387.
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    25. Murilla GA, Peregrine AS, Ndung'u JM, Holmes PH, Eisler MC. The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle. Acta Trop. 2002 Mar; 81(3):185-95. PMID: 11835895.
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    26. Eisler MC, Brandt J, Bauer B, Clausen PH, Delespaux V, Holmes PH, Ilemobade A, Machila N, Mbwambo H, McDermott J, Mehlitz D, Murilla G, Ndung'u JM, Peregrine AS, Sidibé I, Sinyangwe L, Geerts S. Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle. Vet Parasitol. 2001 Jun 12; 97(3):171-82. PMID: 11390069.
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    27. Gibson WC, Stevens JR, Mwendia CM, Ngotho JN, Ndung'u JM. Unravelling the phylogenetic relationships of African trypanosomes of suids. Parasitology. 2001 Jun; 122(Pt 6):625-31. PMID: 11444615.
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    28. Ouma JO, Masake RA, Masiga DK, Moloo SK, Njuguna JT, Ndung'u JM. Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: glossinidae). Acta Trop. 2000 May 31; 75(3):315-21. PMID: 10838215.
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    29. Ngure RM, Gateri LM, Ngotho JM, Ndung'u JM. Application of the Vettest 8008 system for the biochemical analysis of vervet monkey plasma. Vet Rec. 2000 May 20; 146(21):612-3. PMID: 10870765.
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    30. Kamau SW, Omukuba J, Kiragu J, Masika P, Ndung'u JM, Wachira P, Mehlitz D. Financial analysis of animal trypanosomiasis control using cypermethrin pour-on in Kenya. Prev Vet Med. 2000 Apr 28; 44(3-4):231-46. PMID: 10760405.
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    31. Murilla GA, Eisler MC, Peregrine AS, Ndung'u JM, Holmes PH. Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle. J Vet Pharmacol Ther. 1999 Oct; 22(5):301-7. PMID: 10597533.
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    32. Murilla GA, Holmes PH, Peregrine AS, Eisler MC, Ndung'u JM. Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA). J Vet Pharmacol Ther. 1999 Oct; 22(5):295-300. PMID: 10597532.
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    33. Sternberg JM, Njogu Maina N, Gickhuki CW, Ndung'U JM. Nitric oxide production in vervet monkeys (Cercopithecus aethiops) infected with Trypanosoma brucei. Parasite Immunol. 1998 Aug; 20(8):395-7. PMID: 9767605.
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    34. Mwangi EK, Stevenson P, Ndung'U JM, Stear MJ, Reid SW, Gettinby G, Murray M. Studies on host resistance to tick infestations among trypanotolerant Bos indicus cattle breeds in east Africa. Ann N Y Acad Sci. 1998 Jun 29; 849:195-208. PMID: 9668465.
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    35. Burudi EM, Karanja SM, Njue AI, Githiori JB, Ndung'u JM. Establishment of a partly DFMO-sensitive primate model of Trypanosoma rhodesiense sleeping sickness. Acta Trop. 1995 Mar; 59(1):71-3. PMID: 7785528.
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    36. Ndung'u JM, Wright NG, Jennings FW, Murray M. Changes in atrial natriuretic factor and plasma renin activity in dogs infected with Trypanosoma brucei. Parasitol Res. 1992; 78(7):553-6. PMID: 1438145.
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    37. Ndung'u JM, Eckersall PD, Jennings FW. Elevation of the concentration of acute phase proteins in dogs infected with Trypanosoma brucei. Acta Trop. 1991 Jun; 49(2):77-86. PMID: 1680282.
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    38. Jennings FW, McNeil PE, Ndung'u JM, Murray M. Trypanosomiasis and encephalitis: possible aetiology and treatment. Trans R Soc Trop Med Hyg. 1989 Jul-Aug; 83(4):518-9. PMID: 2617602.
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