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Dr Gehad ElGhazali

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Safar HA, Chehadeh SEH, Abdel-Wareth L, Haq A, Jelinek HF, ElGhazali G, Anouti FA. Vitamin D receptor gene polymorphisms among Emirati patients with type 2 diabetes mellitus. J Steroid Biochem Mol Biol. 2018 01; 175:119-124. PMID: 28323045.
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    2. Osman AE, Mubasher M, ElSheikh NE, AlHarthi H, AlZahrani MS, Ahmed N, ElGhazali G, Bradley BA, Fadil AS. Association of single nucleotide polymorphisms in pro-inflammatory cytokine and toll-like receptor genes with pediatric hematogenous osteomyelitis. Genet Mol Res. 2016 May 23; 15(2). PMID: 27323068.
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    3. Conti F, Lugo-Reyes SO, Blancas Galicia L, He J, Aksu G, Borges de Oliveira E, Deswarte C, Hubeau M, Karaca N, de Suremain M, Guérin A, Baba LA, Prando C, Guerrero GG, Emiroglu M, Öz FN, Yamazaki Nakashimada MA, Gonzalez Serrano E, Espinosa S, Barlan I, Pérez N, Regairaz L, Guidos Morales HE, Bezrodnik L, Di Giovanni D, Dbaibo G, Ailal F, Galicchio M, Oleastro M, Chemli J, Danielian S, Perez L, Ortega MC, Soto Lavin S, Hertecant J, Anal O, Kechout N, Al-Idrissi E, ElGhazali G, Bondarenko A, Chernyshova L, Ciznar P, Herbigneaux RM, Diabate A, Ndaga S, Konte B, Czarna A, Migaud M, Pedraza-Sánchez S, Zaidi MB, Vogt G, Blanche S, Benmustapha I, Mansouri D, Abel L, Boisson-Dupuis S, Mahlaoui N, Bousfiha AA, Picard C, Barbouche R, Al-Muhsen S, Espinosa-Rosales FJ, Kütükçüler N, Condino-Neto A, Casanova JL, Bustamante J. Mycobacterial disease in patients with chronic granulomatous disease: A retrospective analysis of 71 cases. J Allergy Clin Immunol. 2016 07; 138(1):241-248.e3. PMID: 26936803.
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    4. Osman AE, Mubasher M, ElSheikh NE, AlHarthi H, AlAlallah IA, Elbeshir AA, Abashar M, Elsidig N, ElGhazali G, Fadil AS. Investigation of polymorphisms in anti-inflammatory cytokine genes in hematogenous osteomyelitis. Genet Mol Res. 2015 Dec 15; 14(4):16981-6. PMID: 26681045.
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    5. Osman AE, Eltayeb-ELSheikh N, Mubasher M, Al Harthi H, Alharbi S, Hamza MA, ElGhazali G. Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D). Hum Immunol. 2016 Jan; 77(1):110-114. PMID: 26542066.
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    6. Abu-Zeid YA, Jasem WS, Lebwohl B, Green PH, ElGhazali G. Seroprevalence of celiac disease among United Arab Emirates healthy adult nationals: a gender disparity. World J Gastroenterol. 2014 Nov 14; 20(42):15830-6. PMID: 25400469.
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    7. Osman AE, Mubasher M, ElSheikh NE, AlHarthi H, Al Yami AS, Rajalingam R, Al-Dehaimi A, Middleton D, ElGhazali G. Characterization of human killer immunoglobulin-like receptors (KIRs) among healthy Saudis. Hum Immunol. 2014 Jun; 75(6):536-40. PMID: 24613458.
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    8. Prando C, Samarina A, Bustamante J, Boisson-Dupuis S, Cobat A, Picard C, AlSum Z, Al-Jumaah S, Al-Hajjar S, Frayha H, Alangari A, Al-Mousa H, Mobaireek KF, Ben-Mustapha I, Adimi P, Feinberg J, de Suremain M, Jannière L, Filipe-Santos O, Mansouri N, Stephan JL, Nallusamy R, Kumararatne DS, Bloorsaz MR, Ben-Ali M, Elloumi-Zghal H, Chemli J, Bouguila J, Bejaoui M, Alaki E, AlFawaz TS, Al Idrissi E, ElGhazali G, Pollard AJ, Murugasu B, Wah Lee B, Halwani R, Al-Zahrani M, Al Shehri MA, Al-Zahrani M, Bin-Hussain I, Mahdaviani SA, Parvaneh N, Abel L, Mansouri D, Barbouche R, Al-Muhsen S, Casanova JL. Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds. Medicine (Baltimore). 2013 Mar; 92(2):109-22. PMID: 23429356.
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    9. Giha HA, Nasr AA, Iriemenam NC, Berzins K, Troye-Blomberg M, Arnot DE, Elghazali G. A malaria serological map indicating the intersection between parasite antigenic diversity and host antibody repertoires. Eur J Clin Microbiol Infect Dis. 2012 Nov; 31(11):3117-25. PMID: 22744729.
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    10. Tsumura M, Okada S, Sakai H, Yasunaga S, Ohtsubo M, Murata T, Obata H, Yasumi T, Kong XF, Abhyankar A, Heike T, Nakahata T, Nishikomori R, Al-Muhsen S, Boisson-Dupuis S, Casanova JL, Alzahrani M, Shehri MA, Elghazali G, Takihara Y, Kobayashi M. Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial disease. Hum Mutat. 2012 Sep; 33(9):1377-87. PMID: 22573496.
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    11. Giha HA, Nasr A, Iriemenam NC, Troye-Blomberg M, Berzins K, ElGhazali G. Lack of significant influence for Fc?RIIa-RH131 or hemoglobin AA/AS polymorphisms on immunity and susceptibility to uncomplicated malaria and existence of marked linkage between the two polymorphisms in Daraweesh. Microbes Infect. 2012 Jun; 14(6):537-44. PMID: 22289203.
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    12. Ahlin E, Elshafei A, Nur M, El Safi SH, Johan R, Elghazali G. Anti-citrullinated peptide antibodies and rheumatoid factor in Sudanese patients with Leishmania donovani infection. Rev Bras Reumatol. 2011 Dec; 51(6):579-86. PMID: 22124592.
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    13. Nasr A, Iriemenam NC, Troye-Blomberg M, Arnot D, Theander TG, Berzins K, Giha HA, Elghazali G. Pattern of pre-existing IgG subclass responses to a panel of asexual stage malaria antigens reported during the lengthy dry season in Daraweesh, Sudan. Scand J Immunol. 2011 Oct; 74(4):390-6. PMID: 21645028.
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    14. Giha HA, Nasr A, Iriemenam NC, Troye-Blomberg M, Berzins K, Pandey JP, Elghazali G. Associations of multi-locus polymorphisms in an immune network with susceptibility to uncomplicated Plasmodium falciparum malaria in Daraweesh village, Eastern Sudan. Infect Genet Evol. 2011 Oct; 11(7):1674-81. PMID: 21729768.
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    15. Chentoufi AA, Gaudreau S, Nguyen A, Sabha M, Amrani A, Elghazali G. Type I diabetes-associated tolerogenic properties of interleukin-2. Clin Dev Immunol. 2011; 2011:289343. PMID: 21647403.
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    16. Mirghani RA, Chowdhary G, Elghazali G. Distribution of the major cytochrome P450 (CYP) 2C9 genetic variants in a Saudi population. Basic Clin Pharmacol Toxicol. 2011 Aug; 109(2):111-4. PMID: 21371265.
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    17. Khalil MK, Nadrah HM, Al Yahia OA, ElGhazali G. Seroresponse to the second measles vaccine dose at school entry in Qassim province, Saudi Arabia. East Mediterr Health J. 2011 Mar; 17(3):191-5. PMID: 21735958.
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    18. Elshafie AI, Hlin E, Håkansson LD, Elghazali G, Safi SH, Rönnelid J, Venge P. Activity and turnover of eosinophil and neutrophil granulocytes are altered in visceral leishmaniasis. Int J Parasitol. 2011 Mar; 41(3-4):463-9. PMID: 21172349.
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    19. Eltahir EM, El Ghazali G, A-Elgadir TM, A-Elbasit IE, Elbashir MI, Giha HA. Raised plasma insulin level and homeostasis model assessment (HOMA) score in cerebral malaria: evidence for insulin resistance and marker of virulence. Acta Biochim Pol. 2010; 57(4):513-20. PMID: 21140005.
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    20. Mirghani RA, Elagib I, Elghazali G, Hellgren U, Gustafsson LL. Effects of Plasmodium falciparum infection on the pharmacokinetics of quinine and its metabolites in pregnant and non-pregnant Sudanese women. Eur J Clin Pharmacol. 2010 Dec; 66(12):1229-34. PMID: 20717655.
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    21. Al-Idrissi E, ElGhazali G, Alzahrani M, Ménasché G, Pachlopnik Schmid J, Basile Gde S. Premature birth, respiratory distress, intracerebral hemorrhage, and silvery-gray hair: differential diagnosis of the 3 types of Griscelli syndrome. J Pediatr Hematol Oncol. 2010 Aug; 32(6):494-6. PMID: 20661159.
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    22. Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, Niehues T, Schuetz C, Malech H, DeRavin SS, Facchetti F, Gennery AR, Andersson E, Kamani NR, Sekiguchi J, Alenezi HM, Chinen J, Dbaibo G, ElGhazali G, Fontana A, Pasic S, Detre C, Terhorst C, Alt FW, Notarangelo LD. Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency. J Exp Med. 2010 Jul 05; 207(7):1541-54. PMID: 20547827.
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    23. Giha HA, ElGhazali G, Nasr A, Iriemenam NC, Berzins K, Troye-Blomberg M, Theander TG, Arnot D. Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs. Infect Genet Evol. 2010 May; 10(4):481-6. PMID: 20215002.
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    24. Giha HA, Nasr A, Iriemenam NC, Balogun HA, Arnot D, Theander TG, Troye-Blomberg M, Berzins K, ElGhazali G. Age-dependent association between IgG2 and IgG3 subclasses to Pf332-C231 antigen and protection from malaria, and induction of protective antibodies by sub-patent malaria infections, in Daraweesh. Vaccine. 2010 Feb 17; 28(7):1732-9. PMID: 20036751.
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    25. Giha HA, Nasr A, Iriemenam NC, Arnot D, Troye-Blomberg M, Theander TG, Berzins K, ElGhazali G, Pandey JP. Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria. Malar J. 2009 Dec 22; 8:306. PMID: 20028548.
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    26. Giha HA, Nasr A, Ekström M, Israelsson E, Arambepola G, Arnot D, Theander TG, Troye-Blomberg M, Berzins K, Tornvall P, ElGhazali G. Association of a single nucleotide polymorphism in the C-reactive protein gene (-286) with susceptibility to Plasmodium falciparum malaria. Mol Med. 2010 Jan-Feb; 16(1-2):27-33. PMID: 19946607.
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    27. Israelsson E, Ekström M, Nasr A, Dolo A, Kearsley S, Arambepola G, Homann MV, Maiga B, Doumbo OK, Elghazali G, Giha HA, Troye-Blomberg M, Berzins K, Tornvall P. Marked differences in CRP genotype frequencies between the Fulani and sympatric ethnic groups in Africa. Malar J. 2009 Jun 22; 8:136. PMID: 19545442.
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    28. Nasr A, Iriemenam NC, Giha HA, Balogun HA, Anders RF, Troye-Blomberg M, ElGhazali G, Berzins K. FcgammaRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan. Malar J. 2009 Mar 13; 8:43. PMID: 19284648.
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    29. Giha HA, Elghazali G, A-Elgadir TM, A-Elbasit IE, Elbashir MI. Severe malaria in an unstable setting: clinical and laboratory correlates of cerebral malaria and severe malarial anemia and a paradigm for a simplified severity scoring. Eur J Clin Microbiol Infect Dis. 2009 Jun; 28(6):661-5. PMID: 19002725.
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    30. Iriemenam NC, Khirelsied AH, Nasr A, ElGhazali G, Giha HA, Elhassan A-Elgadir TM, Agab-Aldour AA, Montgomery SM, Anders RF, Theisen M, Troye-Blomberg M, Elbashir MI, Berzins K. Antibody responses to a panel of Plasmodium falciparum malaria blood-stage antigens in relation to clinical disease outcome in Sudan. Vaccine. 2009 Jan 01; 27(1):62-71. PMID: 18977268.
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    31. Giha HA, Elbashir MI, A-Elbasit IE, A-Gadir TM, ElGhazali G. Bimodal transmission of cerebral malaria and severe malarial anemia and reciprocal co-existence of sexual and asexual parasitemia in an area of seasonal malaria transmission. Parasitol Res. 2008 Jun; 103(1):81-5. PMID: 18299893.
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    32. Giha HA, ElGhazali G, A-Elgadir TM, A-Elbasit IE, Elbashir MI. No evidence for implication of quinine treatment failure in development and fatality of cerebral malaria in Eastern Sudan. Int J Antimicrob Agents. 2008 Jul; 32(1):92-4. PMID: 18499404.
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    33. Díaz de Ståhl T, Sandgren J, Piotrowski A, Nord H, Andersson R, Menzel U, Bogdan A, Thuresson AC, Poplawski A, von Tell D, Hansson CM, Elshafie AI, Elghazali G, Imreh S, Nordenskjöld M, Upadhyaya M, Komorowski J, Bruder CE, Dumanski JP. Profiling of copy number variations (CNVs) in healthy individuals from three ethnic groups using a human genome 32 K BAC-clone-based array. Hum Mutat. 2008 Mar; 29(3):398-408. PMID: 18058796.
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    34. Ali MM, Elghazali G, Montgomery SM, Farouk SE, Nasr A, Noori SI, Shamad MM, Fadlelseed OE, Berzins K. Fc gamma RIIa (CD32) polymorphism and onchocercal skin disease: implications for the development of severe reactive onchodermatitis (ROD). Am J Trop Med Hyg. 2007 Dec; 77(6):1074-8. PMID: 18165525.
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    35. A-Elgadir TM, Elbashir MI, Berzins K, Masuadi EM, A-Elbasit IE, ElGhazali G, Giha HA. The profile of IgG-antibody response against merozoite surface proteins 1 and 2 in severe Plasmodium falciparum malaria in Eastern Sudan. Parasitol Res. 2008 Feb; 102(3):401-9. PMID: 18038151.
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    36. Nasr A, Elghazali G, Giha H, Troye-Blomberg M, Berzins K. Interethnic differences in carriage of haemoglobin AS and Fcgamma receptor IIa (CD32) genotypes in children living in eastern Sudan. Acta Trop. 2008 Feb; 105(2):191-5. PMID: 18022136.
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    37. Ferwerda B, McCall MB, Alonso S, Giamarellos-Bourboulis EJ, Mouktaroudi M, Izagirre N, Syafruddin D, Kibiki G, Cristea T, Hijmans A, Hamann L, Israel S, ElGhazali G, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Hermsen CC, Stalenhoef AF, van Crevel R, Brunner HG, Oh DY, Schumann RR, de la Rúa C, Sauerwein R, Kullberg BJ, van der Ven AJ, van der Meer JW, Netea MG. TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans. Proc Natl Acad Sci U S A. 2007 Oct 16; 104(42):16645-50. PMID: 17925445.
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    38. A-Elbasit IE, ElGhazali G, A-Elgadir TM, Hamad AA, Babiker HA, Elbashir MI, Giha HA. Allelic polymorphism of MSP2 gene in severe P. falciparum malaria in an area of low and seasonal transmission. Parasitol Res. 2007 Dec; 102(1):29-34. PMID: 17768641.
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    39. Nasr A, Iriemenam NC, Troye-Blomberg M, Giha HA, Balogun HA, Osman OF, Montgomery SM, ElGhazali G, Berzins K. Fc gamma receptor IIa (CD32) polymorphism and antibody responses to asexual blood-stage antigens of Plasmodium falciparum malaria in Sudanese patients. Scand J Immunol. 2007 Jul; 66(1):87-96. PMID: 17587350.
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    40. Pandey JP, Nasr A, Rocca KM, Troy-Blomberg M, Elghazali G. Significant differences in GM allotype frequencies between two sympatric tribes with markedly differential susceptibility to malaria. Parasite Immunol. 2007 May; 29(5):267-9. PMID: 17430550.
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    41. Elshafie AI, Ahlin E, Mathsson L, ElGhazali G, Rönnelid J. Circulating immune complexes (IC) and IC-induced levels of GM-CSF are increased in sudanese patients with acute visceral Leishmania donovani infection undergoing sodium stibogluconate treatment: implications for disease pathogenesis. J Immunol. 2007 Apr 15; 178(8):5383-9. PMID: 17404324.
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    42. Elamin NE, Elbashir MI, Elkhidir IM, Elghazali G, Blasczyk R, Horn PA. Identification of four new HLA-Cw alleles in the Sudanese population. Tissue Antigens. 2007 Mar; 69(3):270-2. PMID: 17493153.
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    43. Abdelrahim II, Adam I, Elghazali G, Gustafsson LL, Elbashir MI, Mirghani RA. Pharmacokinetics of quinine and its metabolites in pregnant Sudanese women with uncomplicated Plasmodium falciparum malaria. J Clin Pharm Ther. 2007 Feb; 32(1):15-9. PMID: 17286785.
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    44. A-Elbasit IE, A-Elgadir TM, Elghazali G, Elbashir MI, Giha HA. Genetic fingerprints of parasites causing severe malaria in a setting of low transmission in Sudan. J Mol Microbiol Biotechnol. 2007; 13(1-3):89-95. PMID: 17693716.
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    45. ElShafie AI, Elghazali G, Rönnelid J, Venge P. Cystatin C as a marker of immune complex-associated renal impairment in a Sudanese population with visceral leishmaniasis. Am J Trop Med Hyg. 2006 Nov; 75(5):864-8. PMID: 17123978.
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    46. A-Elgadir TM, Theander TG, Elghazali G, Nielsen MA, A-Elbasit IE, Adam I, Troye-Blomberg M, Elbashir MI, Giha HA. Determinants of variant surface antigen antibody response in severe Plasmodium falciparum malaria in an area of low and unstable malaria transmission. Scand J Immunol. 2006 Mar; 63(3):232-40. PMID: 16499577.
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    47. Giha HA, Elbashir MI, A-Elbasit IE, A-Elgadir TM, ElGhazali GE, Mackinnon MJ, Babiker HA. Drug resistance-virulence relationship in Plasmodium falciparum causing severe malaria in an area of seasonal and unstable transmission. Acta Trop. 2006 Feb; 97(2):181-7. PMID: 16336938.
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    48. Giha HA, A-Elbasit IE, A-Elgadir TM, Adam I, Berzins K, Elghazali G, Elbashir MI. Cerebral malaria is frequently associated with latent parasitemia among the semi-immune population of eastern Sudan. Microbes Infect. 2005 Aug-Sep; 7(11-12):1196-203. PMID: 15994107.
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    49. Giha HA, Elghazali G, A-Elgadir TM, A-Elbasit IE, Eltahir EM, Baraka OZ, Khier MM, Adam I, Troye-Blomberg M, Theander TG, Elbashir MI. Clinical pattern of severe Plasmodium falciparum malaria in Sudan in an area characterized by seasonal and unstable malaria transmission. Trans R Soc Trop Med Hyg. 2005 Apr; 99(4):243-51. PMID: 15708383.
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    50. Mohammed AO, Elghazali G, Mohammed HB, Elbashir MI, Xu S, Berzins K, Venge P. Human neutrophil lipocalin: a specific marker for neutrophil activation in severe Plasmodium falciparum malaria. Acta Trop. 2003 Jul; 87(2):279-85. PMID: 12826303.
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    51. Elghazali G, Adam I, Hamad A, El-Bashir MI. Plasmodium falciparum infection during pregnancy in an unstable transmission area in eastern Sudan. East Mediterr Health J. 2003 Jul; 9(4):570-80. PMID: 15748054.
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    52. Nyakeriga MA, Troye-Blomberg M, Bereczky S, Perlmann H, Perlmann P, ElGhazali G. Immunoglobulin E (IgE) containing complexes induce IL-4 production in human basophils: effect on Th1-Th2 balance in malaria. Acta Trop. 2003 Apr; 86(1):55-62. PMID: 12711103.
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    53. Troye-Blomberg M, Worku S, Tangteerawatana P, Jamshaid R, Söderström K, Elghazali G, Moretta L, Hammarström M, Mincheva-Nilsson L. Human gamma delta T cells that inhibit the in vitro growth of the asexual blood stages of the Plasmodium falciparum parasite express cytolytic and proinflammatory molecules. Scand J Immunol. 1999 Dec; 50(6):642-50. PMID: 10607313.
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    54. Liu Y, Loftenius A, ElGhazali G, Troye-Blomberg M, Ma S, Ekstrand J. Differential regulation of in vitro cytokine production by human blood cells in response to methylmethacrylate. J Toxicol Environ Health A. 1999 Feb 12; 56(3):165-82. PMID: 9973002.
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    55. Perlmann P, Perlmann H, ElGhazali G, Blomberg MT. IgE and tumor necrosis factor in malaria infection. Immunol Lett. 1999 Jan; 65(1-2):29-33. PMID: 10065623.
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    56. Elghazali G, Perlmann H, Rutta AS, Perlmann P, Troye-Blomberg M. Elevated plasma levels of IgE in Plasmodium falciparum-primed individuals reflect an increased ratio of IL-4 to interferon-gamma (IFN-gamma)-producing cells. Clin Exp Immunol. 1997 Jul; 109(1):84-9. PMID: 9218829.
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    57. Perlmann P, Perlmann H, Flyg BW, Hagstedt M, Elghazali G, Worku S, Fernandez V, Rutta AS, Troye-Blomberg M. Immunoglobulin E, a pathogenic factor in Plasmodium falciparum malaria. Infect Immun. 1997 Jan; 65(1):116-21. PMID: 8975900.
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    58. Elghazali G, Esposito F, Troye-Blomberg M. Comparison of the number of IL-4 and IFN-gamma secreting cells in response to the malaria vaccine candidate antigen Pf155/RESA in two groups of naturally primed individuals living in a malaria endemic area in Burkina Faso. Scand J Immunol. 1995 Jul; 42(1):39-45. PMID: 7631143.
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    59. Troye-Blomberg M, Olerup O, Perlmann H, Larsson A, Elghazali G, Fogdell A, Jepsen A, Lepers JP, Pandey JP, Grunewald J, et al. Characterization of regulatory T-cell responses in humans induced by the P. Falciparum blood stage antigen Pf155/RESA. Behring Inst Mitt. 1994 Dec; (95):97-105. PMID: 7755513.
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