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Dr Hela Kallel

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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ben Azoun S, Belhaj AE, Göngrich R, Gasser B, Kallel H. Molecular optimization of rabies virus glycoprotein expression in Pichia pastoris. Microb Biotechnol. 2016 May; 9(3):355-68. PMID: 26880068; PMCID: PMC4835572.
    2. Kallel H, Kamen AA. Large-scale adenovirus and poxvirus-vectored vaccine manufacturing to enable clinical trials. Biotechnol J. 2015 May; 10(5):741-7. PMID: 25914340.
      View in: PubMed
    3. Ben Abdallah F, Lagha R, Said K, Kallel H, Gharbi J. Detection of cell surface hydrophobicity, biofilm and fimbirae genes in salmonella isolated from tunisian clinical and poultry meat. Iran J Public Health. 2014 Apr; 43(4):423-31. PMID: 26005652; PMCID: PMC4433723.
    4. Rourou S, Ben Ayed Y, Trabelsi K, Majoul S, Kallel H. An animal component free medium that promotes the growth of various animal cell lines for the production of viral vaccines. Vaccine. 2014 May 19; 32(24):2767-9. PMID: 24583007.
      View in: PubMed
    5. Trabelsi K, Kamen A, Kallel H. Development of a vectored vaccine against hepatitis E virus. Vaccine. 2014 May 19; 32(24):2808-11. PMID: 24583005.
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    6. Rourou S, Riahi N, Majoul S, Trabelsi K, Kallel H. Development of an in situ detachment protocol of Vero cells grown on Cytodex1 microcarriers under animal component-free conditions in stirred bioreactor. Appl Biochem Biotechnol. 2013 Aug; 170(7):1724-37. PMID: 23737305.
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    7. Kluge S, Rourou S, Vester D, Majoul S, Benndorf D, Genzel Y, Rapp E, Kallel H, Reichl U. Proteome analysis of virus-host cell interaction: rabies virus replication in Vero cells in two different media. Appl Microbiol Biotechnol. 2013 Jun; 97(12):5493-506. PMID: 23674149.
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    8. Abdallah FB, Lagha R, Ellafi A, Namane A, Rousselle JC, Lenormand P, Kallel H. Identification of Outer Membrane Proteins Altered in Response to UVC-Radiation in Vibrio parahaemolyticus and Vibrio alginolyticus. Indian J Microbiol. 2012 Dec; 52(4):660-5. PMID: 24293727; PMCID: PMC3516655.
    9. Gasmi N, Lassoued R, Ayed A, Tréton B, Chevret D, Nicaud JM, Kallel H. Production and characterization of human granulocyte-macrophage colony-stimulating factor (hGM-CSF) expressed in the oleaginous yeast Yarrowia lipolytica. Appl Microbiol Biotechnol. 2012 Oct; 96(1):89-101. PMID: 22627758.
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    10. Rourou S, Hssiki R, Kallel H. Isolation of active peptides from plant hydrolysates that promote Vero cells growth in stirred cultures. BMC Proc. 2011; 5 Suppl 8:P116. PMID: 22373411; PMCID: PMC3285025.
    11. Gasmi N, Ayed A, Ammar BB, Zrigui R, Nicaud JM, Kallel H. Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica. Microb Cell Fact. 2011 Nov 02; 10:90. PMID: 22047602; PMCID: PMC3241208.
    12. Trabelsi K, Majoul S, Rourou S, Kallel H. Development of a measles vaccine production process in MRC-5 cells grown on Cytodex1 microcarriers and in a stirred bioreactor. Appl Microbiol Biotechnol. 2012 Feb; 93(3):1031-40. PMID: 21935589.
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    13. Gasmi N, Ayed A, Nicaud JM, Kallel H. Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b. Microb Cell Fact. 2011 May 20; 10:38. PMID: 21595994; PMCID: PMC3123180.
    14. Chtourou Y, Trabelsi K, Fetoui H, Mkannez G, Kallel H, Zeghal N. Manganese induces oxidative stress, redox state unbalance and disrupts membrane bound ATPases on murine neuroblastoma cells in vitro: protective role of silymarin. Neurochem Res. 2011 Aug; 36(8):1546-57. PMID: 21533646; PMCID: PMC3139064.
    15. Bahloul M, Chabchoub I, Chaari A, Chtara K, Kallel H, Dammak H, Ksibi H, Chelly H, Rekik N, Ben Hamida C, Bouaziz M. Scorpion envenomation among children: clinical manifestations and outcome (analysis of 685 cases). Am J Trop Med Hyg. 2010 Nov; 83(5):1084-92. PMID: 21036842; PMCID: PMC2963974.
    16. Turki S, Jabloun Z, Mrabet G, Marouani A, Thonart P, Diouani MF, Ben Abdallah F, Amara A, Rejeb A, Kallel H. Preliminary safety assessment of Yarrowia lipolytica extracellular lipase: results of acute and 28-day repeated dose oral toxicity studies in rats. Food Chem Toxicol. 2010 Aug-Sep; 48(8-9):2393-400. PMID: 20609427.
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    17. Ben Abdallah F, Bakhrouf A, Ayed A, Kallel H. Alterations of outer membrane proteins and virulence genes expression in gamma-irradiated Vibrio parahaemolyticus and Vibrio alginolyticus. Foodborne Pathog Dis. 2009 Dec; 6(10):1171-6. PMID: 19735197.
      View in: PubMed
    18. Rourou S, van der Ark A, van der Velden T, Kallel H. Development of an animal-component free medium for vero cells culture. Biotechnol Prog. 2009 Nov-Dec; 25(6):1752-61. PMID: 19768803.
      View in: PubMed
    19. Rourou S, van der Ark A, Majoul S, Trabelsi K, van der Velden T, Kallel H. A novel animal-component-free medium for rabies virus production in Vero cells grown on Cytodex 1 microcarriers in a stirred bioreactor. Appl Microbiol Biotechnol. 2009 Nov; 85(1):53-63. PMID: 19521697.
      View in: PubMed
    20. Ben Abdallah F, Chaieb K, Zmantar T, Kallel H, Bakhrouf A. Adherence assays and Slime production of Vibrio alginolyticus and Vibrio parahaemolyticus. Braz J Microbiol. 2009 Apr; 40(2):394-8. PMID: 24031378; PMCID: PMC3769735.
    21. Abdallah FB, Kallel H, Bakhrouf A. Enzymatic, outer membrane proteins and plasmid alterations of starved Vibrio parahaemolyticus and Vibrio alginolyticus cells in seawater. Arch Microbiol. 2009 Jun; 191(6):493-500. PMID: 19373459.
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    22. Turki S, Ayed A, Chalghoumi N, Weekers F, Thonart P, Kallel H. An enhanced process for the production of a highly purified extracellular lipase in the non-conventional yeast Yarrowia lipolytica. Appl Biochem Biotechnol. 2010 Mar; 160(5):1371-85. PMID: 19333561.
      View in: PubMed
    23. Turki S, Kraeim IB, Weeckers F, Thonart P, Kallel H. Isolation of bioactive peptides from tryptone that modulate lipase production in Yarrowia lipolytica. Bioresour Technol. 2009 May; 100(10):2724-31. PMID: 19188062.
      View in: PubMed
    24. Ayed A, Rabhi I, Dellagi K, Kallel H. High level production and purification of human interferon a2b in high cell density culture of Pichia pastoris. Enzyme Microb Technol. 2008 Jan; 42(2):173-80. PMID: 22578868.
      View in: PubMed
    25. Rourou S, van der Ark A, van der Velden T, Kallel H. A microcarrier cell culture process for propagating rabies virus in Vero cells grown in a stirred bioreactor under fully animal component free conditions. Vaccine. 2007 May 10; 25(19):3879-89. PMID: 17307281.
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    26. Smaoui N, Chaabouni M, Sergeev YV, Kallel H, Li S, Mahfoudh N, Maazoul F, Kammoun H, Gandoura N, Bouaziz A, Nouiri E, M'Rad R, Chaabouni H, Hejtmancik JF. Screening of the eight BBS genes in Tunisian families: no evidence of triallelism. Invest Ophthalmol Vis Sci. 2006 Aug; 47(8):3487-95. PMID: 16877420.
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    27. Kallel H, Diouani MF, Loukil H, Trabelsi K, Snoussi MA, Majoul S, Rourou S, Dellagi K. Immunogenicity and efficacy of an in-house developed cell-culture derived veterinarian rabies vaccine. Vaccine. 2006 May 29; 24(22):4856-62. PMID: 16600442.
      View in: PubMed
    28. Trabelsi K, Rourou S, Loukil H, Majoul S, Kallel H. Optimization of virus yield as a strategy to improve rabies vaccine production by Vero cells in a bioreactor. J Biotechnol. 2006 Jan 24; 121(2):261-71. PMID: 16153733.
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    29. Kallel H, Rourou S, Majoul S, Loukil H. A novel process for the production of a veterinary rabies vaccine in BHK-21 cells grown on microcarriers in a 20-l bioreactor. Appl Microbiol Biotechnol. 2003 Jun; 61(5-6):441-6. PMID: 12764557.
      View in: PubMed
    30. Kallel H, Jouini A, Majoul S, Rourou S. Evaluation of various serum and animal protein free media for the production of a veterinary rabies vaccine in BHK-21 cells. J Biotechnol. 2002 May 23; 95(3):195-204. PMID: 12007860.
      View in: PubMed
    31. Kallel H, Zaïri H, Rourou S, Essafi M, Barbouche R, Dellagi K, Fathallah DM. Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask. Cytotechnology. 2002 May; 39(1):9-14. PMID: 19003299; PMCID: PMC3449801.
    32. Merten OW, Kallel H, Manuguerra JC, Tardy-Panit M, Crainic R, Delpeyroux F, Van der Werf S, Perrin P. The new medium MDSS2N, free of any animal protein supports cell growth and production of various viruses. Cytotechnology. 1999 Jul; 30(1-3):191-201. PMID: 19003369; PMCID: PMC3449943.
    33. Chouaib A, Kallel H. [Virus production laboratory]. Arch Inst Pasteur Tunis. 1997 Jan-Apr; 74(1-2):113-4. PMID: 15945188.
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