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Professor Nicolas Glaichenhaus

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chabry J, Nicolas S, Cazareth J, Murris E, Guyon A, Glaichenhaus N, Heurteaux C, Petit-Paitel A. Enriched environment decreases microglia and brain macrophages inflammatory phenotypes through adiponectin-dependent mechanisms: Relevance to depressive-like behavior. Brain Behav Immun. 2015 Nov; 50:275-287. PMID: 26209808.
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    2. Nicolas S, Veyssière J, Gandin C, Zsürger N, Pietri M, Heurteaux C, Glaichenhaus N, Petit-Paitel A, Chabry J. Neurogenesis-independent antidepressant-like effects of enriched environment is dependent on adiponectin. Psychoneuroendocrinology. 2015 Jul; 57:72-83. PMID: 25889841.
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    3. Navarro S, Lazzari A, Kanda A, Fleury S, Dombrowicz D, Glaichenhaus N, Julia V. Bystander immunotherapy as a strategy to control allergen-driven airway inflammation. Mucosal Immunol. 2015 Jul; 8(4):841-51. PMID: 25425267.
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    4. Staumont-Sallé D, Fleury S, Lazzari A, Molendi-Coste O, Hornez N, Lavogiez C, Kanda A, Wartelle J, Fries A, Pennino D, Mionnet C, Prawitt J, Bouchaert E, Delaporte E, Glaichenhaus N, Staels B, Julia V, Dombrowicz D. CX3CL1 (fractalkine) and its receptor CX3CR1 regulate atopic dermatitis by controlling effector T cell retention in inflamed skin. J Exp Med. 2014 Jun 02; 211(6):1185-96. PMID: 24821910; PMCID: PMC4042636.
    5. Campisi L, Soudja SM, Cazareth J, Bassand D, Lazzari A, Brau F, Narni-Mancinelli E, Glaichenhaus N, Geissmann F, Lauvau G. Splenic CD8a? dendritic cells undergo rapid programming by cytosolic bacteria and inflammation to induce protective CD8? T-cell memory. Eur J Immunol. 2011 Jun; 41(6):1594-605. PMID: 21469106.
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    6. Morlacchi S, Dal Secco V, Soldani C, Glaichenhaus N, Viola A, Sarukhan A. Regulatory T cells target chemokine secretion by dendritic cells independently of their capacity to regulate T cell proliferation. J Immunol. 2011 Jun 15; 186(12):6807-14. PMID: 21572026.
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    7. Mougneau E, Bihl F, Glaichenhaus N. Cell biology and immunology of Leishmania. Immunol Rev. 2011 Mar; 240(1):286-96. PMID: 21349100.
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    8. Ortiz-Stern A, Kanda A, Mionnet C, Cazareth J, Lazzari A, Fleury S, Dombrowicz D, Glaichenhaus N, Julia V. Langerin+ dendritic cells are responsible for LPS-induced reactivation of allergen-specific Th2 responses in postasthmatic mice. Mucosal Immunol. 2011 May; 4(3):343-53. PMID: 21048704.
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    9. Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M, Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz D, Glaichenhaus N, Julia V. CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung. Nat Med. 2010 Nov; 16(11):1305-12. PMID: 21037587.
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    10. Muraille E, Gounon P, Cazareth J, Hoebeke J, Lippuner C, Davalos-Misslitz A, Aebischer T, Muller S, Glaichenhaus N, Mougneau E. Direct visualization of peptide/MHC complexes at the surface and in the intracellular compartments of cells infected in vivo by Leishmania major. PLoS Pathog. 2010 Oct 14; 6(10):e1001154. PMID: 20976202; PMCID: PMC2954901.
    11. Navarro S, Cossalter G, Chiavaroli C, Kanda A, Fleury S, Lazzari A, Cazareth J, Sparwasser T, Dombrowicz D, Glaichenhaus N, Julia V. The oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airways. Mucosal Immunol. 2011 Jan; 4(1):53-65. PMID: 20811345.
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    12. Bihl F, Pecheur J, Bréart B, Poupon G, Cazareth J, Julia V, Glaichenhaus N, Braud VM. Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection. J Immunol. 2010 Aug 15; 185(4):2174-81. PMID: 20624944.
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    13. Mosconi E, Rekima A, Seitz-Polski B, Kanda A, Fleury S, Tissandie E, Monteiro R, Dombrowicz DD, Julia V, Glaichenhaus N, Verhasselt V. Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol. 2010 Sep; 3(5):461-74. PMID: 20485331.
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    14. Zavialov AV, Gracia E, Glaichenhaus N, Franco R, Zavialov AV, Lauvau G. Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages. J Leukoc Biol. 2010 Aug; 88(2):279-90. PMID: 20453107.
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    15. Filipe-Santos O, Pescher P, Breart B, Lippuner C, Aebischer T, Glaichenhaus N, Späth GF, Bousso P. A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection. Cell Host Microbe. 2009 Jul 23; 6(1):23-33. PMID: 19616763.
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    16. Glaichenhaus N. [A new vision for autoimmunity]. Med Sci (Paris). 2008 Nov; 24(11):895-6. PMID: 19038081.
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    17. Bajénoff M, Glaichenhaus N, Germain RN. Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone. J Immunol. 2008 Sep 15; 181(6):3947-54. PMID: 18768849; PMCID: PMC2596721.
    18. Campisi L, Brau F, Glaichenhaus N. Imaging host-pathogen interactions. Immunol Rev. 2008 Feb; 221:188-99. PMID: 18275483.
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    19. Verhasselt V, Milcent V, Cazareth J, Kanda A, Fleury S, Dombrowicz D, Glaichenhaus N, Julia V. Breast milk-mediated transfer of an antigen induces tolerance and protection from allergic asthma. Nat Med. 2008 Feb; 14(2):170-5. PMID: 18223654.
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    20. Narni-Mancinelli E, Campisi L, Bassand D, Cazareth J, Gounon P, Glaichenhaus N, Lauvau G. Memory CD8+ T cells mediate antibacterial immunity via CCL3 activation of TNF/ROI+ phagocytes. J Exp Med. 2007 Sep 03; 204(9):2075-87. PMID: 17698589; PMCID: PMC2118695.
    21. Le Roux D, Lankar D, Yuseff MI, Vascotto F, Yokozeki T, Faure-André G, Mougneau E, Glaichenhaus N, Manoury B, Bonnerot C, Lennon-Duménil AM. Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptor. Mol Biol Cell. 2007 Sep; 18(9):3451-62. PMID: 17596518; PMCID: PMC1951757.
    22. Vascotto F, Lankar D, Faure-André G, Vargas P, Diaz J, Le Roux D, Yuseff MI, Sibarita JB, Boes M, Raposo G, Mougneau E, Glaichenhaus N, Bonnerot C, Manoury B, Lennon-Duménil AM. The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol. 2007 Mar 26; 176(7):1007-19. PMID: 17389233; PMCID: PMC2064085.
    23. Muraille E, Narni-Mancinelli E, Gounon P, Bassand D, Glaichenhaus N, Lenz LL, Lauvau G. Cytosolic expression of SecA2 is a prerequisite for long-term protective immunity. Cell Microbiol. 2007 Jun; 9(6):1445-54. PMID: 17244189.
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    24. Bajénoff M, Egen JG, Koo LY, Laugier JP, Brau F, Glaichenhaus N, Germain RN. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity. 2006 Dec; 25(6):989-1001. PMID: 17112751; PMCID: PMC2692293.
    25. Iezzi G, Fröhlich A, Ernst B, Ampenberger F, Saeland S, Glaichenhaus N, Kopf M. Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection. J Immunol. 2006 Jul 15; 177(2):1250-6. PMID: 16818784.
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    26. Bajénoff M, Breart B, Huang AY, Qi H, Cazareth J, Braud VM, Germain RN, Glaichenhaus N. Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med. 2006 Mar 20; 203(3):619-31. PMID: 16505138; PMCID: PMC2118232.
    27. De Trez C, Pajak B, Brait M, Glaichenhaus N, Urbain J, Moser M, Lauvau G, Muraille E. TLR4 and Toll-IL-1 receptor domain-containing adapter-inducing IFN-beta, but not MyD88, regulate Escherichia coli-induced dendritic cell maturation and apoptosis in vivo. J Immunol. 2005 Jul 15; 175(2):839-46. PMID: 16002681.
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    28. Benigni F, Zimmermann VS, Hugues S, Caserta S, Basso V, Rivino L, Ingulli E, Malherbe L, Glaichenhaus N, Mondino A. Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk. J Immunol. 2005 Jul 15; 175(2):739-48. PMID: 16002669.
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    29. Zhang Y, Renkvist N, Sun Z, Schuler-Thurner B, Glaichenhaus N, Schuler G, Boon T, van der Bruggen P, Colau D. A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells. Eur J Immunol. 2005 Apr; 35(4):1066-75. PMID: 15756643.
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    30. Ferlin WG, Mougneau E, Hugues S, Appel H, Jang MH, Cazareth J, Beaudoin L, Schricke C, Lehuen A, Wucherpfennig KW, Glaichenhaus N. Self-peptides that bind with low affinity to the diabetes-associated I-A(g7) molecule readily induce T cell tolerance in non-obese diabetic mice. Eur J Immunol. 2004 Oct; 34(10):2656-63. PMID: 15368281.
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    31. Lauvau G, Glaichenhaus N. Mini-review: Presentation of pathogen-derived antigens in vivo. Eur J Immunol. 2004 Apr; 34(4):913-20. PMID: 15048701.
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    32. Masteller EL, Warner MR, Ferlin W, Judkowski V, Wilson D, Glaichenhaus N, Bluestone JA. Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes. J Immunol. 2003 Nov 15; 171(10):5587-95. PMID: 14607967.
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    33. Hofman V, Brousset P, Mougneau E, Marty P, Lamant L, Antoine JC, Glaichenhaus N, Hofman P. Immunostaining of visceral leishmaniasis caused by Leishmania infantum using monoclonal antibody (19-11) to the Leishmania homologue of receptors for activated C-kinase. Am J Clin Pathol. 2003 Oct; 120(4):567-74. PMID: 14560568.
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    34. Kishore U, Zhang W, Corlett L, Waters P, Glaichenhaus N, Willcox N. Use of peptide: HLA class II complexes to study specific T cells in autoimmune myasthenia gravis. Ann N Y Acad Sci. 2003 Sep; 998:339-42. PMID: 14592893.
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    35. Shah JA, Darrah PA, Ambrozak DR, Turon TN, Mendez S, Kirman J, Wu CY, Glaichenhaus N, Seder RA. Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice. J Exp Med. 2003 Jul 21; 198(2):281-91. PMID: 12874261; PMCID: PMC2194077.
    36. Filippi C, Hugues S, Cazareth J, Julia V, Glaichenhaus N, Ugolini S. CD4+ T cell polarization in mice is modulated by strain-specific major histocompatibility complex-independent differences within dendritic cells. J Exp Med. 2003 Jul 21; 198(2):201-9. PMID: 12860929; PMCID: PMC2194066.
    37. Moro M, Filippi C, Gallard A, Malherbe L, Foucras G, Akiba H, Yagita H, Guéry JC, Glaichenhaus N. Blockade of CD86 in BALB/c mice infected with Leishmania major does not prevent the expansion of low avidity T cells. Eur J Immunol. 2002 Dec; 32(12):3566-75. PMID: 12516542.
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    38. Mougneau E, Hugues S, Glaichenhaus N. Antigen presentation by dendritic cells in vivo. J Exp Med. 2002 Oct 21; 196(8):1013-6. PMID: 12391012; PMCID: PMC2194035.
    39. Hugues S, Malherbe L, Filippi C, Glaichenhaus N. Generation and use of alternative multimers of peptide/MHC complexes. J Immunol Methods. 2002 Oct 01; 268(1):83-92. PMID: 12213345.
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    40. Soussi N, Saklani-Jusforgues H, Colle JH, Milon G, Glaichenhaus N, Goossens PL. Effect of intragastric and intraperitoneal immunisation with attenuated and wild-type LACK-expressing Listeria monocytogenes on control of murine Leishmania major infection. Vaccine. 2002 Jun 21; 20(21-22):2702-12. PMID: 12034096.
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    41. Hugues S, Mougneau E, Ferlin W, Jeske D, Hofman P, Homann D, Beaudoin L, Schrike C, Von Herrath M, Lehuen A, Glaichenhaus N. Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells. Immunity. 2002 Feb; 16(2):169-81. PMID: 11869679.
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    42. Julia V, Hessel EM, Malherbe L, Glaichenhaus N, O'Garra A, Coffman RL. A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. Immunity. 2002 Feb; 16(2):271-83. PMID: 11869687.
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    43. Elliott T, Bonneville M, Kruisbeek A, Walker PR, Essayan D, Glaichenhaus N, Vyakarnam A, Casanova JL, Liu Y, AuchinclossJr H, Waneck G, LeGuern C, Akdis C. Paper alert. Immunology. Curr Opin Immunol. 2001 Dec; 13(6):625-34. PMID: 11677080.
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    44. Wang Q, Malherbe L, Zhang D, Zingler K, Glaichenhaus N, Killeen N. CD4 promotes breadth in the TCR repertoire. J Immunol. 2001 Oct 15; 167(8):4311-20. PMID: 11591754.
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    45. Schilling S, Glaichenhaus N. T cells that react to the immunodominant Leishmania major LACK antigen prevent early dissemination of the parasite in susceptible BALB/c mice. Infect Immun. 2001 Feb; 69(2):1212-4. PMID: 11160025; PMCID: PMC98009.
    46. Torrentera FA, Glaichenhaus N, Laman JD, Carlier Y. T-cell responses to immunodominant LACK antigen do not play a critical role in determining susceptibility of BALB/c mice to Leishmania mexicana. Infect Immun. 2001 Jan; 69(1):617-21. PMID: 11119565; PMCID: PMC97931.
    47. Malherbe L, Filippi C, Julia V, Foucras G, Moro M, Appel H, Wucherpfennig K, Guéry JC, Glaichenhaus N. Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major. Immunity. 2000 Dec; 13(6):771-82. PMID: 11163193.
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    48. Ferlin W, Glaichenhaus N, Mougneau E. Present difficulties and future promise of MHC multimers in autoimmune exploration. Curr Opin Immunol. 2000 Dec; 12(6):670-5. PMID: 11102771.
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    49. Julia V, McSorley SS, Malherbe L, Breittmayer JP, Girard-Pipau F, Beck A, Glaichenhaus N. Priming by microbial antigens from the intestinal flora determines the ability of CD4+ T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major. J Immunol. 2000 Nov 15; 165(10):5637-45. PMID: 11067920.
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    50. Stobie L, Gurunathan S, Prussin C, Sacks DL, Glaichenhaus N, Wu CY, Seder RA. The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8427-32. PMID: 10890924; PMCID: PMC26964.
    51. Gurunathan S, Stobie L, Prussin C, Sacks DL, Glaichenhaus N, Iwasaki A, Fowell DJ, Locksley RM, Chang JT, Wu CY, Seder RA. Requirements for the maintenance of Th1 immunity in vivo following DNA vaccination: a potential immunoregulatory role for CD8+ T cells. J Immunol. 2000 Jul 15; 165(2):915-24. PMID: 10878366.
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    52. Soussi N, Milon G, Colle JH, Mougneau E, Glaichenhaus N, Goossens PL. Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major. Infect Immun. 2000 Mar; 68(3):1498-506. PMID: 10678966; PMCID: PMC97307.
    53. Hofman V, Marty P, Perrin C, Saint-Paul MC, Le Fichoux Y, Michiels JF, Glaichenhaus N, Pratlong F, Hofman P. The histological spectrum of visceral leishmaniasis caused by Leishmania infantum MON-1 in acquired immune deficiency syndrome. Hum Pathol. 2000 Jan; 31(1):75-84. PMID: 10665917.
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    54. Julia V, Glaichenhaus N. CD4(+) T cells which react to the Leishmania major LACK antigen rapidly secrete interleukin-4 and are detrimental to the host in resistant B10.D2 mice. Infect Immun. 1999 Jul; 67(7):3641-4. PMID: 10377151; PMCID: PMC116556.
    55. Pingel S, Launois P, Fowell DJ, Turck CW, Southwood S, Sette A, Glaichenhaus N, Louis JA, Locksley RM. Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope. J Exp Med. 1999 Apr 05; 189(7):1111-20. PMID: 10190902; PMCID: PMC2193001.
    56. Courret N, Prina E, Mougneau E, Saraiva EM, Sacks DL, Glaichenhaus N, Antoine JC. Presentation of the Leishmania antigen LACK by infected macrophages is dependent upon the virulence of the phagocytosed parasites. Eur J Immunol. 1999 Mar; 29(3):762-73. PMID: 10092078.
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    57. Maizels R, Langhorne J, Glaichenhaus N. Pathogenic and protective responses in parasitic infections. Res Immunol. 1998 Nov-Dec; 149(9):875-7. PMID: 9923646.
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    58. McSorley SJ, Rask C, Pichot R, Julia V, Czerkinsky C, Glaichenhaus N. Selective tolerization of Th1-like cells after nasal administration of a cholera toxoid-LACK conjugate. Eur J Immunol. 1998 Feb; 28(2):424-32. PMID: 9521049.
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    59. Gurunathan S, Sacks DL, Brown DR, Reiner SL, Charest H, Glaichenhaus N, Seder RA. Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J Exp Med. 1997 Oct 06; 186(7):1137-47. PMID: 9314562; PMCID: PMC2199076.
    60. McSorley SJ, Soldera S, Malherbe L, Carnaud C, Locksley RM, Flavell RA, Glaichenhaus N. Immunological tolerance to a pancreatic antigen as a result of local expression of TNFalpha by islet beta cells. Immunity. 1997 Sep; 7(3):401-9. PMID: 9324360.
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    61. Soldera S, McSorley SJ, Glaichenhaus N. Selective down-regulation of Th2 immune responses following treatment with antigen-coupled splenocytes. Eur J Immunol. 1997 Apr; 27(4):848-54. PMID: 9130634.
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    62. Julia V, Rassoulzadegan M, Glaichenhaus N. Resistance to Leishmania major induced by tolerance to a single antigen. Science. 1996 Oct 18; 274(5286):421-3. PMID: 8832890.
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    63. Prina E, Lang T, Glaichenhaus N, Antoine JC. Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J Immunol. 1996 Jun 01; 156(11):4318-27. PMID: 8666803.
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    64. Mougneau E, Altare F, Wakil AE, Zheng S, Coppola T, Wang ZE, Waldmann R, Locksley RM, Glaichenhaus N. Expression cloning of a protective Leishmania antigen. Science. 1995 Apr 28; 268(5210):563-6. PMID: 7725103.
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    65. Vidal F, Mougneau E, Glaichenhaus N, Vaigot P, Darmon M, Cuzin F. Coordinated posttranscriptional control of gene expression by modular elements including Alu-like repetitive sequences. Proc Natl Acad Sci U S A. 1993 Jan 01; 90(1):208-12. PMID: 8419925; PMCID: PMC45629.
    66. Glaichenhaus N, Davis C, Bornschlegel K, Allison JP, Shastri N. A novel strategy for the generation of T cell lines lacking expression of endogenous alpha- and/or beta-chain T cell receptor genes. J Immunol. 1991 Apr 01; 146(7):2095-101. PMID: 1826016.
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    67. Glaichenhaus N, Shastri N, Littman DR, Turner JM. Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells. Cell. 1991 Feb 08; 64(3):511-20. PMID: 1671341.
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    68. Glaichenhaus N, Mougneau E, Connan G, Rassoulzadegan M, Cuzin F. Cooperation between multiple oncogenes in rodent embryo fibroblasts: an experimental model of tumor progression? Adv Cancer Res. 1985; 45:291-305. PMID: 3004122.
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    69. Glaichenhaus N, Galup C, Mougneau E, Cuzin F. Does the large T protein of polyoma virus regulate the expression of the cellular myc gene? Curr Top Microbiol Immunol. 1984; 113:20-5. PMID: 6090063.
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    70. Rassoulzadegan M, Cowie A, Carr A, Glaichenhaus N, Kamen R, Cuzin F. The roles of individual polyoma virus early proteins in oncogenic transformation. Nature. 1982 Dec 23; 300(5894):713-8. PMID: 6294529.
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    71. Rautmann G, Glaichenhaus N, Nahgashfar Z, Breathnach R, Rassoulzadegan M. Complementation of a tsa mutant and replication of a recombinant DNA carrying the viral ori region in mouse cells transformed by polyoma virus. Virology. 1982 Oct 30; 122(2):306-17. PMID: 6293177.
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