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Professor Marcelo Jacobs-lorena

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang S, Dos-Santos ALA, Huang W, Liu KC, Oshaghi MA, Wei G, Agre P, Jacobs-Lorena M. Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria. Science. 2017 Sep 29; 357(6358):1399-1402. PMID: 28963255.
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    2. Cha SJ, Kim MS, Pandey A, Jacobs-Lorena M. Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion. J Exp Med. 2016 Sep 19; 213(10):2099-112. PMID: 27551151; PMCID: PMC5030802 [Available on 03/19/17].
    3. McLean KJ, Jacobs-Lorena M. Genetic Control Of Malaria Mosquitoes. Trends Parasitol. 2016 Mar; 32(3):174-6. PMID: 26809567.
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    4. Ruiz A, Pérez D, Muñoz MC, Molina JM, Taubert A, Jacobs-Lorena M, Vega-Rodríguez J, López AM, Hermosilla C. Targeting essential Eimeria ninakohlyakimovae sporozoite ligands for caprine host endothelial cell invasion with a phage display peptide library. Parasitol Res. 2015 Nov; 114(11):4327-31. PMID: 26341796.
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    5. Cha SJ, Park K, Srinivasan P, Schindler CW, van Rooijen N, Stins M, Jacobs-Lorena M. CD68 acts as a major gateway for malaria sporozoite liver infection. J Exp Med. 2015 Aug 24; 212(9):1391-403. PMID: 26216124; PMCID: PMC4548058.
    6. Smith RC, Barillas-Mury C, Jacobs-Lorena M. Hemocyte differentiation mediates the mosquito late-phase immune response against Plasmodium in Anopheles gambiae. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):E3412-20. PMID: 26080400; PMCID: PMC4491748.
    7. Vega-Rodriguez J, Perez-Barreto D, Ruiz-Reyes A, Jacobs-Lorena M. Targeting molecular interactions essential for Plasmodium sexual reproduction. Cell Microbiol. 2015 Nov; 17(11):1594-604. PMID: 25944054; PMCID: PMC4668941.
    8. Ke H, Lewis IA, Morrisey JM, McLean KJ, Ganesan SM, Painter HJ, Mather MW, Jacobs-Lorena M, Llinás M, Vaidya AB. Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle. Cell Rep. 2015 Apr 07; 11(1):164-74. PMID: 25843709; PMCID: PMC4394047.
    9. Smith RC, Jacobs-Lorena M. Malaria parasite Pfs47 disrupts JNK signaling to escape mosquito immunity. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1250-1. PMID: 25617364; PMCID: PMC4321270.
    10. Ferrer P, Vega-Rodriguez J, Tripathi AK, Jacobs-Lorena M, Sullivan DJ. Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition. Antimicrob Agents Chemother. 2015 Mar; 59(3):1418-26. PMID: 25512427; PMCID: PMC4325789.
    11. Wiley JD, Merino EF, Krai PM, McLean KJ, Tripathi AK, Vega-Rodríguez J, Jacobs-Lorena M, Klemba M, Cassera MB. Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum. Eukaryot Cell. 2015 Feb; 14(2):128-39. PMID: 25446055; PMCID: PMC4311923.
    12. Smith RC, Vega-Rodríguez J, Jacobs-Lorena M. The Plasmodium bottleneck: malaria parasite losses in the mosquito vector. Mem Inst Oswaldo Cruz. 2014 Aug; 109(5):644-61. PMID: 25185005; PMCID: PMC4156458.
    13. Vega-Rodríguez J, Ghosh AK, Kanzok SM, Dinglasan RR, Wang S, Bongio NJ, Kalume DE, Miura K, Long CA, Pandey A, Jacobs-Lorena M. Multiple pathways for Plasmodium ookinete invasion of the mosquito midgut. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):E492-500. PMID: 24474798; PMCID: PMC3910608.
    14. Smith RC, Kizito C, Rasgon JL, Jacobs-Lorena M. Transgenic mosquitoes expressing a phospholipase A(2) gene have a fitness advantage when fed Plasmodium falciparum-infected blood. PLoS One. 2013; 8(10):e76097. PMID: 24098427; PMCID: PMC3788000.
    15. Eappen AG, Smith RC, Jacobs-Lorena M. Enterobacter-activated mosquito immune responses to Plasmodium involve activation of SRPN6 in Anopheles stephensi. PLoS One. 2013; 8(5):e62937. PMID: 23658788; PMCID: PMC3643921.
    16. Ikadai H, Shaw Saliba K, Kanzok SM, McLean KJ, Tanaka TQ, Cao J, Williamson KC, Jacobs-Lorena M. Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):E1676-84. PMID: 23572579; PMCID: PMC3645567.
    17. Wang S, Jacobs-Lorena M. Genetic approaches to interfere with malaria transmission by vector mosquitoes. Trends Biotechnol. 2013 Mar; 31(3):185-93. PMID: 23395485; PMCID: PMC3593784.
    18. Ghosh AK, Jacobs-Lorena M. In Vitro Differentiation of Plasmodium falciparum Gametocytes into Ookinetes. Methods Mol Biol. 2013; 923:27-33. PMID: 22990769; PMCID: PMC4666676.
    19. Saliba KS, Jacobs-Lorena M. Production of Plasmodium falciparum gametocytes in vitro. Methods Mol Biol. 2013; 923:17-25. PMID: 22990768; PMCID: PMC4672730.
    20. Smith RC, Eappen AG, Radtke AJ, Jacobs-Lorena M. Regulation of anti-Plasmodium immunity by a LITAF-like transcription factor in the malaria vector Anopheles gambiae. PLoS Pathog. 2012; 8(10):e1002965. PMID: 23093936; PMCID: PMC3475675.
    21. Wang S, Ghosh AK, Bongio N, Stebbings KA, Lampe DJ, Jacobs-Lorena M. Fighting malaria with engineered symbiotic bacteria from vector mosquitoes. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12734-9. PMID: 22802646; PMCID: PMC3412027.
    22. Ghosh AK, Coppens I, Gårdsvoll H, Ploug M, Jacobs-Lorena M. Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):17153-8. PMID: 21949403; PMCID: PMC3193258.
    23. Ghosh AK, Jacobs-Lorena M. Surface-expressed enolases of Plasmodium and other pathogens. Mem Inst Oswaldo Cruz. 2011 Aug; 106 Suppl 1:85-90. PMID: 21881761; PMCID: PMC4153683.
    24. Mikolajczak SA, Sacci JB, De La Vega P, Camargo N, VanBuskirk K, Krzych U, Cao J, Jacobs-Lorena M, Cowman AF, Kappe SH. Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites. Cell Microbiol. 2011 Aug; 13(8):1250-60. PMID: 21569184; PMCID: PMC4155577.
    25. Fang W, Vega-Rodríguez J, Ghosh AK, Jacobs-Lorena M, Kang A, St Leger RJ. Development of transgenic fungi that kill human malaria parasites in mosquitoes. Science. 2011 Feb 25; 331(6020):1074-7. PMID: 21350178; PMCID: PMC4153607.
    26. Ghosh AK, Dinglasan RR, Ikadai H, Jacobs-Lorena M. An improved method for the in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes. Malar J. 2010 Jul 08; 9:194. PMID: 20615232; PMCID: PMC2909250.
    27. Pastrana-Mena R, Dinglasan RR, Franke-Fayard B, Vega-Rodríguez J, Fuentes-Caraballo M, Baerga-Ortiz A, Coppens I, Jacobs-Lorena M, Janse CJ, Serrano AE. Glutathione reductase-null malaria parasites have normal blood stage growth but arrest during development in the mosquito. J Biol Chem. 2010 Aug 27; 285(35):27045-56. PMID: 20573956; PMCID: PMC2930704.
    28. Ghosh AK, Jacobs-Lorena M. Plasmodium sporozoite invasion of the mosquito salivary gland. Curr Opin Microbiol. 2009 Aug; 12(4):394-400. PMID: 19608457; PMCID: PMC2759692.
    29. González-Lázaro M, Dinglasan RR, Hernández-Hernández Fde L, Rodríguez MH, Laclaustra M, Jacobs-Lorena M, Flores-Romo L. Anopheles gambiae Croquemort SCRBQ2, expression profile in the mosquito and its potential interaction with the malaria parasite Plasmodium berghei. Insect Biochem Mol Biol. 2009 May-Jun; 39(5-6):395-402. PMID: 19366631; PMCID: PMC4138513.
    30. Beaty BJ, Prager DJ, James AA, Jacobs-Lorena M, Miller LH, Law JH, Collins FH, Kafatos FC. From Tucson to genomics and transgenics: the vector biology network and the emergence of modern vector biology. PLoS Negl Trop Dis. 2009; 3(3):e343. PMID: 19333394; PMCID: PMC2659576.
    31. Vega-Rodríguez J, Franke-Fayard B, Dinglasan RR, Janse CJ, Pastrana-Mena R, Waters AP, Coppens I, Rodríguez-Orengo JF, Srinivasan P, Jacobs-Lorena M, Serrano AE. The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission. PLoS Pathog. 2009 Feb; 5(2):e1000302. PMID: 19229315; PMCID: PMC2636896.
    32. Ghosh AK, Devenport M, Jethwaney D, Kalume DE, Pandey A, Anderson VE, Sultan AA, Kumar N, Jacobs-Lorena M. Malaria parasite invasion of the mosquito salivary gland requires interaction between the Plasmodium TRAP and the Anopheles saglin proteins. PLoS Pathog. 2009 Jan; 5(1):e1000265. PMID: 19148273; PMCID: PMC2613030.
    33. Srinivasan P, Coppens I, Jacobs-Lorena M. Distinct roles of Plasmodium rhomboid 1 in parasite development and malaria pathogenesis. PLoS Pathog. 2009 Jan; 5(1):e1000262. PMID: 19148267; PMCID: PMC2607553.
    34. Dinglasan RR, Devenport M, Florens L, Johnson JR, McHugh CA, Donnelly-Doman M, Carucci DJ, Yates JR, Jacobs-Lorena M. The Anopheles gambiae adult midgut peritrophic matrix proteome. Insect Biochem Mol Biol. 2009 Feb; 39(2):125-34. PMID: 19038338; PMCID: PMC2684889.
    35. Dinglasan RR, Jacobs-Lorena M. Flipping the paradigm on malaria transmission-blocking vaccines. Trends Parasitol. 2008 Aug; 24(8):364-70. PMID: 18599352; PMCID: PMC4153682.
    36. Rodrigues FG, Santos MN, de Carvalho TX, Rocha BC, Riehle MA, Pimenta PF, Abraham EG, Jacobs-Lorena M, Alves de Brito CF, Moreira LA. Expression of a mutated phospholipase A2 in transgenic Aedes fluviatilis mosquitoes impacts Plasmodium gallinaceum development. Insect Mol Biol. 2008 Apr; 17(2):175-83. PMID: 18353106; PMCID: PMC4137777.
    37. Li C, Marrelli MT, Yan G, Jacobs-Lorena M. Fitness of transgenic Anopheles stephensi mosquitoes expressing the SM1 peptide under the control of a vitellogenin promoter. J Hered. 2008 May-Jun; 99(3):275-82. PMID: 18334506; PMCID: PMC4154370.
    38. Srinivasan P, Fujioka H, Jacobs-Lorena M. PbCap380, a novel oocyst capsule protein, is essential for malaria parasite survival in the mosquito. Cell Microbiol. 2008 Jun; 10(6):1304-12. PMID: 18248630; PMCID: PMC4137771.
    39. Yoshida S, Shimada Y, Kondoh D, Kouzuma Y, Ghosh AK, Jacobs-Lorena M, Sinden RE. Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development. PLoS Pathog. 2007 Dec; 3(12):e192. PMID: 18159942; PMCID: PMC2151087.
    40. Dinglasan RR, Alaganan A, Ghosh AK, Saito A, van Kuppevelt TH, Jacobs-Lorena M. Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion. Proc Natl Acad Sci U S A. 2007 Oct 02; 104(40):15882-7. PMID: 17873063; PMCID: PMC2000438.
    41. Dinglasan RR, Kalume DE, Kanzok SM, Ghosh AK, Muratova O, Pandey A, Jacobs-Lorena M. Disruption of Plasmodium falciparum development by antibodies against a conserved mosquito midgut antigen. Proc Natl Acad Sci U S A. 2007 Aug 14; 104(33):13461-6. PMID: 17673553; PMCID: PMC1948931.
    42. Sodja A, Fujioka H, Lemos FJ, Donnelly-Doman M, Jacobs-Lorena M. Induction of actin gene expression in the mosquito midgut by blood ingestion correlates with striking changes of cell shape. J Insect Physiol. 2007 Aug; 53(8):833-9. PMID: 17537455; PMCID: PMC2756156.
    43. Marrelli MT, Li C, Rasgon JL, Jacobs-Lorena M. Transgenic malaria-resistant mosquitoes have a fitness advantage when feeding on Plasmodium-infected blood. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5580-3. PMID: 17372227; PMCID: PMC1838510.
    44. Moreira CK, Rodrigues FG, Ghosh A, Varotti Fde P, Miranda A, Daffre S, Jacobs-Lorena M, Moreira LA. Effect of the antimicrobial peptide gomesin against different life stages of Plasmodium spp. Exp Parasitol. 2007 Aug; 116(4):346-53. PMID: 17376436; PMCID: PMC1978196.
    45. Riehle MA, Moreira CK, Lampe D, Lauzon C, Jacobs-Lorena M. Using bacteria to express and display anti-Plasmodium molecules in the mosquito midgut. Int J Parasitol. 2007 May; 37(6):595-603. PMID: 17224154.
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    46. Devenport M, Alvarenga PH, Shao L, Fujioka H, Bianconi ML, Oliveira PL, Jacobs-Lorena M. Identification of the Aedes aegypti peritrophic matrix protein AeIMUCI as a heme-binding protein. Biochemistry. 2006 Aug 08; 45(31):9540-9. PMID: 16878988.
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    47. Marrelli MT, Moreira CK, Kelly D, Alphey L, Jacobs-Lorena M. Mosquito transgenesis: what is the fitness cost? Trends Parasitol. 2006 May; 22(5):197-202. PMID: 16564223.
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    48. Kanzok SM, Jacobs-Lorena M. Entomopathogenic fungi as biological insecticides to control malaria. Trends Parasitol. 2006 Feb; 22(2):49-51. PMID: 16377249.
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    49. Dinglasan RR, Jacobs-Lorena M. Insight into a conserved lifestyle: protein-carbohydrate adhesion strategies of vector-borne pathogens. Infect Immun. 2005 Dec; 73(12):7797-807. PMID: 16299269; PMCID: PMC1307025.
    50. Abraham EG, Pinto SB, Ghosh A, Vanlandingham DL, Budd A, Higgs S, Kafatos FC, Jacobs-Lorena M, Michel K. An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites. Proc Natl Acad Sci U S A. 2005 Nov 08; 102(45):16327-32. PMID: 16260729; PMCID: PMC1283470.
    51. Shao L, Devenport M, Fujioka H, Ghosh A, Jacobs-Lorena M. Identification and characterization of a novel peritrophic matrix protein, Ae-Aper50, and the microvillar membrane protein, AEG12, from the mosquito, Aedes aegypti. Insect Biochem Mol Biol. 2005 Sep; 35(9):947-59. PMID: 15978997.
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    52. Abraham EG, Donnelly-Doman M, Fujioka H, Ghosh A, Moreira L, Jacobs-Lorena M. Driving midgut-specific expression and secretion of a foreign protein in transgenic mosquitoes with AgAper1 regulatory elements. Insect Mol Biol. 2005 Jun; 14(3):271-9. PMID: 15926896.
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    53. Xu X, Dong Y, Abraham EG, Kocan A, Srinivasan P, Ghosh AK, Sinden RE, Ribeiro JM, Jacobs-Lorena M, Kafatos FC, Dimopoulos G. Transcriptome analysis of Anopheles stephensi-Plasmodium berghei interactions. Mol Biochem Parasitol. 2005 Jul; 142(1):76-87. PMID: 15907562.
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    54. Riehle MA, Jacobs-Lorena M. Using bacteria to express and display anti-parasite molecules in mosquitoes: current and future strategies. Insect Biochem Mol Biol. 2005 Jul; 35(7):699-707. PMID: 15894187.
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    55. Devenport M, Fujioka H, Donnelly-Doman M, Shen Z, Jacobs-Lorena M. Storage and secretion of Ag-Aper14, a novel peritrophic matrix protein, and Ag-Muc1 from the mosquito Anopheles gambiae. Cell Tissue Res. 2005 Apr; 320(1):175-85. PMID: 15726420.
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    56. Brotto MA, Marrelli MT, Brotto LS, Jacobs-Lorena M, Nosek TM. Functional and biochemical modifications in skeletal muscles from malarial mice. Exp Physiol. 2005 May; 90(3):417-25. PMID: 15728139.
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    57. Moreira CK, Marrelli MT, Jacobs-Lorena M. Gene expression in Plasmodium: from gametocytes to sporozoites. Int J Parasitol. 2004 Dec; 34(13-14):1431-40. PMID: 15582520.
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    58. Devenport M, Fujioka H, Jacobs-Lorena M. Storage and secretion of the peritrophic matrix protein Ag-Aper1 and trypsin in the midgut of Anopheles gambiae. Insect Mol Biol. 2004 Aug; 13(4):349-58. PMID: 15271206.
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    59. Abraham EG, Jacobs-Lorena M. Mosquito midgut barriers to malaria parasite development. Insect Biochem Mol Biol. 2004 Jul; 34(7):667-71. PMID: 15242707.
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    60. Moreira LA, Wang J, Collins FH, Jacobs-Lorena M. Fitness of anopheline mosquitoes expressing transgenes that inhibit Plasmodium development. Genetics. 2004 Mar; 166(3):1337-41. PMID: 15082552; PMCID: PMC1470781.
    61. Abraham EG, Islam S, Srinivasan P, Ghosh AK, Valenzuela JG, Ribeiro JM, Kafatos FC, Dimopoulos G, Jacobs-Lorena M. Analysis of the Plasmodium and Anopheles transcriptional repertoire during ookinete development and midgut invasion. J Biol Chem. 2004 Feb 13; 279(7):5573-80. PMID: 14627712.
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    62. Srinivasan P, Abraham EG, Ghosh AK, Valenzuela J, Ribeiro JM, Dimopoulos G, Kafatos FC, Adams JH, Fujioka H, Jacobs-Lorena M. Analysis of the Plasmodium and Anopheles transcriptomes during oocyst differentiation. J Biol Chem. 2004 Feb 13; 279(7):5581-7. PMID: 14627711; PMCID: PMC4674691.
    63. Riehle MA, Srinivasan P, Moreira CK, Jacobs-Lorena M. Towards genetic manipulation of wild mosquito populations to combat malaria: advances and challenges. J Exp Biol. 2003 Nov; 206(Pt 21):3809-16. PMID: 14506216.
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    64. Villalon JM, Ghosh A, Jacobs-Lorena M. The peritrophic matrix limits the rate of digestion in adult Anopheles stephensi and Aedes aegypti mosquitoes. J Insect Physiol. 2003 Oct; 49(10):891-5. PMID: 14511821.
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    65. Jacobs-Lorena M. Interrupting malaria transmission by genetic manipulation of anopheline mosquitoes. J Vector Borne Dis. 2003 Sep-Dec; 40(3-4):73-7. PMID: 15119075.
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    66. Ghosh A, Srinivasan P, Abraham EG, Fujioka H, Jacobs-Lorena M. Molecular strategies to study Plasmodium-mosquito interactions. Trends Parasitol. 2003 Feb; 19(2):94-101. PMID: 12586478.
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    67. Moreira LA, Ghosh AK, Abraham EG, Jacobs-Lorena M. Genetic transformation of mosquitoes: a quest for malaria control. Int J Parasitol. 2002 Dec 04; 32(13):1599-605. PMID: 12435444.
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    68. Alphey L, Beard CB, Billingsley P, Coetzee M, Crisanti A, Curtis C, Eggleston P, Godfray C, Hemingway J, Jacobs-Lorena M, James AA, Kafatos FC, Mukwaya LG, Paton M, Powell JR, Schneider W, Scott TW, Sina B, Sinden R, Sinkins S, Spielman A, Touré Y, Collins FH. Malaria control with genetically manipulated insect vectors. Science. 2002 Oct 04; 298(5591):119-21. PMID: 12364786.
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    69. Ghosh AK, Moreira LA, Jacobs-Lorena M. Plasmodium-mosquito interactions, phage display libraries and transgenic mosquitoes impaired for malaria transmission. Insect Biochem Mol Biol. 2002 Oct; 32(10):1325-31. PMID: 12225923.
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    70. Moreira LA, Ito J, Ghosh A, Devenport M, Zieler H, Abraham EG, Crisanti A, Nolan T, Catteruccia F, Jacobs-Lorena M. Bee venom phospholipase inhibits malaria parasite development in transgenic mosquitoes. J Biol Chem. 2002 Oct 25; 277(43):40839-43. PMID: 12167627.
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    71. Ito J, Ghosh A, Moreira LA, Wimmer EA, Jacobs-Lorena M. Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite. Nature. 2002 May 23; 417(6887):452-5. PMID: 12024215.
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    72. Pascoa V, Oliveira PL, Dansa-Petretski M, Silva JR, Alvarenga PH, Jacobs-Lorena M, Lemos FJ. Aedes aegypti peritrophic matrix and its interaction with heme during blood digestion. Insect Biochem Mol Biol. 2002 May; 32(5):517-23. PMID: 11891128.
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    73. Ghosh AK, Ribolla PE, Jacobs-Lorena M. Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13278-81. PMID: 11687659; PMCID: PMC60861.
    74. Ward TW, Jenkins MS, Afanasiev BN, Edwards M, Duda BA, Suchman E, Jacobs-Lorena M, Beaty BJ, Carlson JO. Aedes aegypti transducing densovirus pathogenesis and expression in Aedes aegypti and Anopheles gambiae larvae. Insect Mol Biol. 2001 Oct; 10(5):397-405. PMID: 11881803.
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    75. Fontes AM, Riedl A, Jacobs-Lorena M. Developmental regulation of an instability element from the Drosophila fushi tarazu mRNA. Genesis. 2001 Jun; 30(2):59-64. PMID: 11416864.
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    76. Shao L, Devenport M, Jacobs-Lorena M. The peritrophic matrix of hematophagous insects. Arch Insect Biochem Physiol. 2001 Jun; 47(2):119-25. PMID: 11376458.
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    77. Ito J, Jacobs-Lorena M. Functional mapping of destabilizing elements in the protein-coding region of the Drosophila fushi tarazu mRNA. J Biol Chem. 2001 Jun 29; 276(26):23525-30. PMID: 11306592.
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    78. Marana SR, Jacobs-Lorena M, Terra WR, Ferreira C. Amino acid residues involved in substrate binding and catalysis in an insect digestive beta-glycosidase. Biochim Biophys Acta. 2001 Feb 09; 1545(1-2):41-52. PMID: 11342030.
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    79. Moreira LA, Edwards MJ, Adhami F, Jasinskiene N, James AA, Jacobs-Lorena M. Robust gut-specific gene expression in transgenic Aedes aegypti mosquitoes. Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20):10895-8. PMID: 11005862; PMCID: PMC27120.
    80. Shen Z, Edwards MJ, Jacobs-Lorena M. A gut-specific serine protease from the malaria vector Aanopheles gambiae is downregulated after blood ingestion. Insect Mol Biol. 2000 Jun; 9(3):223-9. PMID: 10886405.
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    81. Ghosh A, Edwards MJ, Jacobs-Lorena M. The journey of the malaria parasite in the mosquito: hopes for the new century. Parasitol Today. 2000 May; 16(5):196-201. PMID: 10782078.
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    82. Edwards MJ, Moskalyk LA, Donelly-Doman M, Vlaskova M, Noriega FG, Walker VK, Jacobs-Lorena M. Characterization of a carboxypeptidase A gene from the mosquito, Aedes aegypti. Insect Mol Biol. 2000 Feb; 9(1):33-8. PMID: 10672069.
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    83. Shen Z, Dimopoulos G, Kafatos FC, Jacobs-Lorena M. A cell surface mucin specifically expressed in the midgut of the malaria mosquito Anopheles gambiae. Proc Natl Acad Sci U S A. 1999 May 11; 96(10):5610-5. PMID: 10318932; PMCID: PMC21908.
    84. Shen Z, Jacobs-Lorena M. Evolution of chitin-binding proteins in invertebrates. J Mol Evol. 1999 Mar; 48(3):341-7. PMID: 10093224.
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    85. Fontes AM, Ito J, Jacobs-Lorena M. Control of messenger RNA stability during development. Curr Top Dev Biol. 1999; 44:171-202. PMID: 9891880.
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    86. Monesi N, Jacobs-Lorena M, Paçó-Larson ML. The DNA puff gene BhC4-1 of Bradysia hygida is specifically transcribed in early prepupal salivary glands of Drosophila melanogaster. Chromosoma. 1998 Dec; 107(8):559-69. PMID: 9933409.
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    87. Shen Z, Jacobs-Lorena M. Nuclear factor recognition sites in the gut-specific enhancer region of an Anopheles gambiae trypsin gene. Insect Biochem Mol Biol. 1998 Dec; 28(12):1007-12. PMID: 9887516.
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    88. Jordan TV, Shike H, Boulo V, Cedeno V, Fang Q, Davis BS, Jacobs-Lorena M, Higgs S, Fryxell KJ, Burns JC. Pantropic retroviral vectors mediate somatic cell transformation and expression of foreign genes in dipteran insects. Insect Mol Biol. 1998 Aug; 7(3):215-22. PMID: 9662470.
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    89. Shen Z, Jacobs-Lorena M. A type I peritrophic matrix protein from the malaria vector Anopheles gambiae binds to chitin. Cloning, expression, and characterization. J Biol Chem. 1998 Jul 10; 273(28):17665-70. PMID: 9651363.
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    90. Surdej P, Jacobs-Lorena M. Developmental regulation of bicoid mRNA stability is mediated by the first 43 nucleotides of the 3' untranslated region. Mol Cell Biol. 1998 May; 18(5):2892-900. PMID: 9566908; PMCID: PMC110668.
    91. Edwards MJ, Lemos FJ, Donnelly-Doman M, Jacobs-Lorena M. Rapid induction by a blood meal of a carboxypeptidase gene in the gut of the mosquito Anopheles gambiae. Insect Biochem Mol Biol. 1997 Dec; 27(12):1063-72. PMID: 9569647.
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    92. Shen Z, Jacobs-Lorena M. Characterization of a novel gut-specific chitinase gene from the human malaria vector Anopheles gambiae. J Biol Chem. 1997 Nov 14; 272(46):28895-900. PMID: 9360958.
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    93. Moskalyk LA, Oo MM, Jacobs-Lorena M. Peritrophic matrix proteins of Anopheles gambiae and Aedes aegypti. Insect Mol Biol. 1996 Nov; 5(4):261-8. PMID: 8933177.
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    94. Lemos FJ, Cornel AJ, Jacobs-Lorena M. Trypsin and aminopeptidase gene expression is affected by age and food composition in Anopheles gambiae. Insect Biochem Mol Biol. 1996 Jul; 26(7):651-8. PMID: 8995788.
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    95. Riedl A, Jacobs-Lorena M. Determinants of Drosophila fushi tarazu mRNA instability. Mol Cell Biol. 1996 Jun; 16(6):3047-53. PMID: 8649416; PMCID: PMC231299.
    96. Shahabuddin M, Lemos FJ, Kaslow DC, Jacobs-Lorena M. Antibody-mediated inhibition of Aedes aegypti midgut trypsins blocks sporogonic development of Plasmodium gallinaceum. Infect Immun. 1996 Mar; 64(3):739-43. PMID: 8641775; PMCID: PMC173831.
    97. Xiong B, Jacobs-Lorena M. The black fly Simulium vittatum trypsin gene: characterization of the 5'-upstream region and induction by the blood meal. Exp Parasitol. 1995 Nov; 81(3):363-70. PMID: 7498433.
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    98. Xiong B, Jacobs-Lorena M. Gut-specific transcriptional regulatory elements of the carboxypeptidase gene are conserved between black flies and Drosophila. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9313-7. PMID: 7568124; PMCID: PMC40975.
    99. Jacobs-Lorena M, Lemos FJ. Immunological strategies for control of insect disease vectors: a critical assessment. Parasitol Today. 1995 Apr; 11(4):144-7. PMID: 15275358.
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    100. Surdej P, Jacobs-Lorena M. Strategy for epitope tagging the protein-coding region of any gene. Biotechniques. 1994 Sep; 17(3):560-5. PMID: 7529515.
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    101. Andersson S, Saebøe-Larssen S, Lambertsson A, Merriam J, Jacobs-Lorena M. A Drosophila third chromosome Minute locus encodes a ribosomal protein. Genetics. 1994 Jun; 137(2):513-20. PMID: 8070662; PMCID: PMC1205974.
    102. Ramos A, Mahowald A, Jacobs-Lorena M. Peritrophic matrix of the black fly Simulium vittatum: formation, structure, and analysis of its protein components. J Exp Zool. 1994 Mar 15; 268(4):269-81. PMID: 8195743.
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    103. Surdej P, Riedl A, Jacobs-Lorena M. Regulation of mRNA stability in development. Annu Rev Genet. 1994; 28:263-82. PMID: 7893126.
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    104. Frydman HM, Cadavid EO, Yokosawa J, Henrique Silva F, Navarro-Cattapan LD, Santelli RV, Jacobs-Lorena M, Graessmann M, Graessmann A, Stocker AJ, et al. Molecular characterization of the DNA puff C-8 gene of Rhynchosciara americana. J Mol Biol. 1993 Oct 20; 233(4):799-803. PMID: 8411183.
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    105. Ramos A, Mahowald A, Jacobs-Lorena M. Gut-specific genes from the black fly Simulium vittatum encoding trypsin-like and carboxypeptidase-like proteins. Insect Mol Biol. 1993; 1(3):149-63. PMID: 8269093.
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    106. Jacobs-Lorena M. Interference of gene expression in Drosophila by antisense ribosomal protein genes integrated into the germ line. Ann N Y Acad Sci. 1992 Oct 28; 660:204-8. PMID: 1340122.
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    107. Patel RC, Jacobs-Lorena M. Cis-acting sequences in the 5'-untranslated region of the ribosomal protein A1 mRNA mediate its translational regulation during early embryogenesis of Drosophila. J Biol Chem. 1992 Jan 15; 267(2):1159-64. PMID: 1730640.
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    108. Patel R, Jacobs-Lorena M. Generation of Minute phenotypes by a transformed antisense ribosomal protein gene. Dev Genet. 1992; 13(4):256-63. PMID: 1291154.
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    109. Hongo S, Jacobs-Lorena M. Translational discrimination of ribosomal protein mRNAs in the early Drosophila embryo. Dev Biol. 1991 Jun; 145(2):338-43. PMID: 1904036.
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    110. Tamate HB, Patel RC, Riedl AE, Jacobs-Lorena M. Overproduction and translational regulation of rp49 ribosomal protein mRNA in transgenic Drosophila carrying extra copies of the gene. Mol Gen Genet. 1990 Apr; 221(2):171-5. PMID: 2370846.
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    111. Qian S, Hongo S, Jacobs-Lorena M. Antisense ribosomal protein gene expression specifically disrupts oogenesis in Drosophila melanogaster. Proc Natl Acad Sci U S A. 1988 Dec; 85(24):9601-5. PMID: 3144001; PMCID: PMC282811.
    112. Kay MA, Zhang JY, Jacobs-Lorena M. Identification and germline transformation of the ribosomal protein rp21 gene of Drosophila: complementation analysis with the Minute QIII locus reveals nonidentity. Mol Gen Genet. 1988 Aug; 213(2-3):354-8. PMID: 3185506.
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    113. Jacobs-Lorena M, Doman M, Mahowald A. Identification of species-specific DNA sequences in North American blackflies. Trop Med Parasitol. 1988 Mar; 39(1):31-4. PMID: 3387825.
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    114. Qian S, Zhang JY, Kay MA, Jacobs-Lorena M. Structural analysis of the Drosophila rpA1 gene, a member of the eucaryotic 'A' type ribosomal protein family. Nucleic Acids Res. 1987 Feb 11; 15(3):987-1003. PMID: 3103101; PMCID: PMC340503.
    115. Jiang QY, Gnagey A, Tandler B, Jacobs-Lorena M. Isolation of plasma membranes from Drosophila embryos. Mol Biol Rep. 1986; 11(1):19-24. PMID: 3003563.
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    116. Kay MA, Jacobs-Lorena M. Selective translational regulation of ribosomal protein gene expression during early development of Drosophila melanogaster. Mol Cell Biol. 1985 Dec; 5(12):3583-92. PMID: 3939320; PMCID: PMC369189.
    117. Al-Atia GR, Fruscoloni P, Jacobs-Lorena M. Translational regulation of mRNAs for ribosomal proteins during early Drosophila development. Biochemistry. 1985 Oct 08; 24(21):5798-803. PMID: 3936537.
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    118. Ruddell A, Jacobs-Lorena M. Biphasic pattern of histone gene expression during Drosophila oogenesis. Proc Natl Acad Sci U S A. 1985 May; 82(10):3316-9. PMID: 3923476; PMCID: PMC397766.
    119. Ruddell A, Jacobs-Lorena M. Preferential expression of actin genes during oogenesis of Drosophila. Dev Biol. 1984 Sep; 105(1):115-20. PMID: 6205919.
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    120. Fruscoloni P, Al-Atia GR, Jacobs-Lorena M. Translational regulation of a specific gene during oogenesis and embryogenesis of Drosophila. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3359-63. PMID: 16593324.
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    121. Ruddell A, Jacobs-Lorena M. Quantitation of individual proteins by a two-stage electrophoresis procedure. Anal Biochem. 1982 May 15; 122(2):248-52. PMID: 6810722.
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    122. Jacobs-Lorena M. Dosage of 5 S and ribosomal genes during oogenesis of Drosophila melanogaster. Dev Biol. 1980 Nov; 80(1):134-45. PMID: 6777216.
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    123. Hough-Evans BR, Jacobs-Lorena M, Cummings MR, Britten RJ, Davidson EH. Complexity of RNA in eggs of Drosophila melanogaster and Musca domestica. Genetics. 1980 May; 95(1):81-94. PMID: 6159251; PMCID: PMC1214223.
    124. Jacobs-Lorena M, Hough-Evans BR, Britten RJ, Davidson EH. Complexity of RNA in developing oocytes of Drosophila melanogaster. Dev Biol. 1980 May; 76(2):509-13. PMID: 6771177.
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    125. Srdic Z, Jacobs-Lorena M. Drosophila egg chambers develop to mature eggs when cultured in vivo. Science. 1978 Nov 10; 202(4368):641-3. PMID: 100884.
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    126. Jacobs-Lorena M, Crippa M. Mass fractionation of Drosophila egg chambers. Dev Biol. 1977 Jun; 57(2):385-92. PMID: 194805.
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    127. Mermod JJ, Jacobs-Lorena M, Crippa M. Changes in rate of RNA synthesis and ribosomal gene number during oogenesis of Drosophila melanogaster. Dev Biol. 1977 Jun; 57(2):393-402. PMID: 406151.
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    128. Jacobs-Lorena M, Gabrielli F, Borun TW, Baglioni C. Studies on the translational control of histone synthesis. I. Translation of histone messenger RNA by heterologous cell-free systems prepared from cells inactive in DNA synthesis. Biochim Biophys Acta. 1973 Oct 12; 324(2):275-81. PMID: 4759458.
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    129. Gross KW, Jacobs-Lorena M, Baglioni C, Gross PR. Cell-free translation of maternal messenger RNA from sea urchin eggs. Proc Natl Acad Sci U S A. 1973 Sep; 70(9):2614-8. PMID: 4582192; PMCID: PMC427067.
    130. Jacobs-Lorena M, Baglioni C. Initiation of histone synthesis by f-met-tRNAf in an ascites cell-free system. Mol Biol Rep. 1973 Aug; 1(2):113-7. PMID: 24197475.
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    131. Gross K, Ruderman J, Jacobs-Lorena M, Baglioni C, Gross PR. Cell-free synthesis of histones directed by messenger RNA from sea urchin embryos. Nat New Biol. 1973 Feb 28; 241(113):272-4. PMID: 4511913.
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    132. Jacobs-Lorena M, Baglioni C. Characterization of a mouse ascites cell-free system. Biochemistry. 1972 Dec 19; 11(26):4970-4. PMID: 4565029.
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    133. Baglioni C, Jacobs-Lorena M, Meade H. The site of action of inhibitors of initiation of protein synthesis in reticulocytes. Biochim Biophys Acta. 1972 Aug 16; 277(1):188-97. PMID: 5053770.
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    134. Jacobs-Lorena M, Baglioni C, Borun TW. Translation of messenger RNA for histones from HeLa cells by a cell-free extract from mouse ascites tumor. Proc Natl Acad Sci U S A. 1972 Aug; 69(8):2095-9. PMID: 4506079; PMCID: PMC426876.
    135. Jacobs-Lorena M, Baglioni C. Messenger RNA for globin in the postribosomal supernatant of rabbit reticulocytes. Proc Natl Acad Sci U S A. 1972 Jun; 69(6):1425-8. PMID: 4504354; PMCID: PMC426717.
    136. Jacobs-Lorena M, Brega A, Baglioni C. Inhibition of protein synthesis in reticulocytes by antibiotics. V. Mechanism of action of pederine, an inhibitor of initiation and elongation. Biochim Biophys Acta. 1971 Jun 30; 240(2):263-72. PMID: 5559977.
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    137. Jacobs-Lorena M, Colombo B, Baglioni C. Inhibition of protein synthesis in reticulocytes by antibiotics. IV. Ribosome behaviour after puromycin release of growing peptide chains. Biochim Biophys Acta. 1970 Nov 12; 224(1):174-83. PMID: 5490252.
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    138. Jacobs-Lorena M, Baglioni C. A study of ribosomal subunits during cell-free protein synthesis. Biochim Biophys Acta. 1970 Nov 12; 224(1):165-73. PMID: 5490251.
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    139. Housman D, Jacobs-Lorena M, Rajbhandary UL, Lodish HF. Initiation of haemoglobin synthesis by methionyl-tRNA. Nature. 1970 Aug 29; 227(5261):913-8. PMID: 4915406.
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    140. Baglioni C, Colombo B, Jacobs-Lorena M. Chain termination: a test for a possible explanation of thalassemia. Ann N Y Acad Sci. 1969 Nov 20; 165(1):212-20. PMID: 5260144.
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    141. Baglioni C, Vesco C, Jacobs-Lorena M. The role of ribosomal subunits in mammalian cells. Cold Spring Harb Symp Quant Biol. 1969; 34:555-65. PMID: 5266177.
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