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Dr Thomas Gordon Egwang

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yagi M, Bang G, Tougan T, Palacpac NM, Arisue N, Aoshi T, Matsumoto Y, Ishii KJ, Egwang TG, Druilhe P, Horii T. Protective epitopes of the Plasmodium falciparum SERA5 malaria vaccine reside in intrinsically unstructured N-terminal repetitive sequences. PLoS One. 2014; 9(6):e98460. PMID: 24886718; PMCID: PMC4041889.
    2. Palacpac NM, Ntege E, Balikagala B, Yeka A, Shirai H, Suzuki N, Nsereko C, Kanoi BN, Okada T, Egwang TG, Horii T. Hematological and biochemical data obtained in rural northern Uganda. Int J Environ Res Public Health. 2014 May 06; 11(5):4870-85. PMID: 24806194; PMCID: PMC4053919.
    3. Ribacke U, Moll K, Albrecht L, Ahmed Ismail H, Normark J, Flaberg E, Szekely L, Hultenby K, Persson KE, Egwang TG, Wahlgren M. Improved in vitro culture of Plasmodium falciparum permits establishment of clinical isolates with preserved multiplication, invasion and rosetting phenotypes. PLoS One. 2013; 8(7):e69781. PMID: 23894537; PMCID: PMC3718792.
    4. Palacpac NM, Ntege E, Yeka A, Balikagala B, Suzuki N, Shirai H, Yagi M, Ito K, Fukushima W, Hirota Y, Nsereko C, Okada T, Kanoi BN, Tetsutani K, Arisue N, Itagaki S, Tougan T, Ishii KJ, Ueda S, Egwang TG, Horii T. Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36. PLoS One. 2013; 8(5):e64073. PMID: 23724021; PMCID: PMC3665850.
    5. Proietti C, Verra F, Bretscher MT, Stone W, Kanoi BN, Balikagala B, Egwang TG, Corran P, Ronca R, Arcà B, Riley EM, Crisanti A, Drakeley C, Bousema T. Influence of infection on malaria-specific antibody dynamics in a cohort exposed to intense malaria transmission in northern Uganda. Parasite Immunol. 2013 May-Jun; 35(5-6):164-73. PMID: 23473542.
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    6. Owalla TJ, Palacpac NM, Shirai H, Horii T, Egwang TG. Association of naturally acquired IgG antibodies against Plasmodium falciparum serine repeat antigen-5 with reduced placental parasitemia and normal birth weight in pregnant Ugandan women: a pilot study. Parasitol Int. 2013 Jun; 62(3):237-9. PMID: 23395684.
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    7. Proietti C, Pettinato DD, Kanoi BN, Ntege E, Crisanti A, Riley EM, Egwang TG, Drakeley C, Bousema T. Continuing intense malaria transmission in northern Uganda. Am J Trop Med Hyg. 2011 May; 84(5):830-7. PMID: 21540398; PMCID: PMC3083756.
    8. Kiyingi HS, Egwang TG, Nannyonga M. Prolonged elevation of viral loads in HIV-1-infected children in a region of intense malaria transmission in Northern Uganda: a prospective cohort study. Pan Afr Med J. 2010; 7:11. PMID: 21918698; PMCID: PMC3172627.
    9. Blomqvist K, Normark J, Nilsson D, Ribacke U, Orikiriza J, Trillkott P, Byarugaba J, Egwang TG, Kironde F, Andersson B, Wahlgren M. var gene transcription dynamics in Plasmodium falciparum patient isolates. Mol Biochem Parasitol. 2010 Apr; 170(2):74-83. PMID: 20006652.
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    10. Normark J, Nilsson D, Ribacke U, Winter G, Moll K, Wheelock CE, Bayarugaba J, Kironde F, Egwang TG, Chen Q, Andersson B, Wahlgren M. PfEMP1-DBL1alpha amino acid motifs in severe disease states of Plasmodium falciparum malaria. Proc Natl Acad Sci U S A. 2007 Oct 02; 104(40):15835-40. PMID: 17895392; PMCID: PMC1994139.
    11. Balyejusa Kizito E, Rönnberg-Wästljung AC, Egwang T, Gullberg U, Fregene M, Westerbergh A. Quantitative trait loci controlling cyanogenic glucoside and dry matter content in cassava (Manihot esculenta Crantz) roots. Hereditas. 2007 Sep; 144(4):129-36. PMID: 17850597.
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    12. Kanoi BN, Egwang TG. New concepts in vaccine development in malaria. Curr Opin Infect Dis. 2007 Jun; 20(3):311-6. PMID: 17471043.
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    13. Ribacke U, Mok BW, Wirta V, Normark J, Lundeberg J, Kironde F, Egwang TG, Nilsson P, Wahlgren M. Genome wide gene amplifications and deletions in Plasmodium falciparum. Mol Biochem Parasitol. 2007 Sep; 155(1):33-44. PMID: 17599553.
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    14. Balyejusa Kizito E, Chiwona-Karltun L, Egwang T, Fregene M, Westerbergh A. Genetic diversity and variety composition of cassava on small-scale farms in Uganda: an interdisciplinary study using genetic markers and farmer interviews. Genetica. 2007 Jul; 130(3):301-18. PMID: 17082904.
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    15. Vogt AM, Pettersson F, Moll K, Jonsson C, Normark J, Ribacke U, Egwang TG, Ekre HP, Spillmann D, Chen Q, Wahlgren M. Release of sequestered malaria parasites upon injection of a glycosaminoglycan. PLoS Pathog. 2006 Sep; 2(9):e100. PMID: 17009869; PMCID: PMC1579244.
    16. Mujuzi G, Magambo B, Okech B, Egwang TG. Pigmented monocytes are negative correlates of protection against severe and complicated malaria in Ugandan children. Am J Trop Med Hyg. 2006 May; 74(5):724-9. PMID: 16687669.
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    17. Okech B, Mujuzi G, Ogwal A, Shirai H, Horii T, Egwang TG. High titers of IgG antibodies against Plasmodium falciparum serine repeat antigen 5 (SERA5) are associated with protection against severe malaria in Ugandan children. Am J Trop Med Hyg. 2006 Feb; 74(2):191-7. PMID: 16474069.
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    18. Talisuna AO, Nalunkuma-Kazibwe A, Langi P, Mutabingwa TK, Watkins WW, Van Marck E, Egwang TG, D'Alessandro U. Two mutations in dihydrofolate reductase combined with one in the dihydropteroate synthase gene predict sulphadoxine-pyrimethamine parasitological failure in Ugandan children with uncomplicated falciparum malaria. Infect Genet Evol. 2004 Dec; 4(4):321-7. PMID: 15374529.
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    19. Ntoumi F, Djimde AA, Mbacham W, Egwang T. The importance and future of malaria research in Africa. Am J Trop Med Hyg. 2004 Aug; 71(2 Suppl):IV. PMID: 15331851.
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    20. Okech BA, Corran PH, Todd J, Joynson-Hicks A, Uthaipibull C, Egwang TG, Holder AA, Riley EM. Fine specificity of serum antibodies to Plasmodium falciparum merozoite surface protein, PfMSP-1(19), predicts protection from malaria infection and high-density parasitemia. Infect Immun. 2004 Mar; 72(3):1557-67. PMID: 14977962; PMCID: PMC356041.
    21. Talisuna AO, Nalunkuma-Kazibwe A, Bakyaita N, Langi P, Mutabingwa TK, Watkins WW, Van Marck E, D'Alessandro U, Egwang TG. Efficacy of sulphadoxine-pyrimethamine alone or combined with amodiaquine or chloroquine for the treatment of uncomplicated falciparum malaria in Ugandan children. Trop Med Int Health. 2004 Feb; 9(2):222-9. PMID: 15040559.
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    22. Alibu VP, Egwang TG. Genomics research and malaria control: great expectations. PLoS Biol. 2003 Nov; 1(2):E39. PMID: 14624242; PMCID: PMC261879.
    23. Talisuna AO, Langi P, Mutabingwa TK, Van Marck E, Speybroeck N, Egwang TG, Watkins WW, Hastings IM, D'Alessandro U. Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria. Int J Parasitol. 2003 Sep 15; 33(10):1051-8. PMID: 13129527.
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    24. Talisuna AO, Langi P, Mutabingwa TK, Watkins W, Van Marck E, Egwang TG, D'Alessandro U. Population-based validation of dihydrofolate reductase gene mutations for the prediction of sulfadoxine-pyrimethamine resistance in Uganda. Trans R Soc Trop Med Hyg. 2003 May-Jun; 97(3):338-42. PMID: 15228255.
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    25. Aoki S, Li J, Itagaki S, Okech BA, Egwang TG, Matsuoka H, Palacpac NM, Mitamura T, Horii T. Serine repeat antigen (SERA5) is predominantly expressed among the SERA multigene family of Plasmodium falciparum, and the acquired antibody titers correlate with serum inhibition of the parasite growth. J Biol Chem. 2002 Dec 06; 277(49):47533-40. PMID: 12244052.
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    26. Talisuna AO, Kyosiimire-Lugemwa J, Langi P, Mutabingwa TK, Watkins W, Van Marck E, Egwang T, D'Alessandro U. Role of the pfcrt codon 76 mutation as a molecular marker for population-based surveillance of chloroquine (CQ)-resistant Plasmodium falciparum malaria in Ugandan sentinel sites with high CQ resistance. Trans R Soc Trop Med Hyg. 2002 Sep-Oct; 96(5):551-6. PMID: 12474488.
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    27. Talisuna AO, Langi P, Bakyaita N, Egwang T, Mutabingwa TK, Watkins W, Van Marck E, D'Alessandro U. Intensity of malaria transmission, antimalarial-drug use and resistance in Uganda: what is the relationship between these three factors? Trans R Soc Trop Med Hyg. 2002 May-Jun; 96(3):310-7. PMID: 12174786.
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    28. Kyosiimire-Lugemwa J, Nalunkuma-Kazibwe AJ, Mujuzi G, Mulindwa H, Talisuna A, Egwang TG. The Lys-76-Thr mutation in PfCRT and chloroquine resistance in Plasmodium falciparum isolates from Uganda. Trans R Soc Trop Med Hyg. 2002 Jan-Feb; 96(1):91-5. PMID: 11926004.
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    29. Okech BA, Nalunkuma A, Okello D, Pang XL, Suzue K, Li J, Horii T, Egwang TG. Natural human immunoglobulin G subclass responses to Plasmodium falciparum serine repeat antigen in Uganda. Am J Trop Med Hyg. 2001 Dec; 65(6):912-7. PMID: 11791998.
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    30. Egwang TG, Apio B, Riley E, Okello D. Plasmodium falciparum malariometric indices in Apac district, northern Uganda. East Afr Med J. 2000 Aug; 77(8):413-6. PMID: 12862063.
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    31. Apio B, Nalunkuma A, Okello D, Riley E, Egwang TG. Human IgG subclass antibodies to the 19 kilodalton carboxy terminal fragment of Plasmodium falciparum merozoite surface protein 1 (MSP1(19)) and predominance of the MAD20 allelic type of MSP1 in Uganda. East Afr Med J. 2000 Apr; 77(4):189-93. PMID: 12858901.
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    32. Kasumba IN, Nalunkuma AJ, Mujuzi G, Kitaka FS, Byaruhanga R, Okong P, Egwang TG. Low birthweight associated with maternal anaemia and Plasmodium falciparum infection during pregnancy, in a peri-urban/urban area of low endemicity in Uganda. Ann Trop Med Parasitol. 2000 Jan; 94(1):7-13. PMID: 10723519.
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    33. Touré FS, Ungeheuer MN, Egwang TG, Deloron P. Use of polymerase chain reaction for accurate follow-up of Loa loa experimental infection in Mandrillus sphinx. Am J Trop Med Hyg. 1999 Dec; 61(6):956-9. PMID: 10674677.
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    34. Touré FS, Mavoungou E, Deloron P, Egwang TG. [Comparative analysis of 2 diagnostic methods of human loiasis: IgG4 serology and nested PCR]. Bull Soc Pathol Exot. 1999 Jul; 92(3):167-70. PMID: 10472442.
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    35. Toure FS, Leroy EM, Mavoungou E, Egwang TG. Sequence conservation of repeat 3 region of the gene coding for the 15 kDa polyprotein within human and simian Loa loa. J Med Primatol. 1999 Apr; 28(2):57-61. PMID: 10431694.
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    36. Toure FS, Deloron P, Egwang TG, Wahl G. [Relationship between the intensity of Loa loa filariasis transmission and prevalence of infections]. Med Trop (Mars). 1999; 59(3):249-52. PMID: 10701202.
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    37. Touré FS, Kassambara L, Williams T, Millet P, Bain O, Georges AJ, Egwang TG. Human occult loiasis: improvement in diagnostic sensitivity by the use of a nested polymerase chain reaction. Am J Trop Med Hyg. 1998 Jul; 59(1):144-9. PMID: 9684643.
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    38. Touré FS, Mavoungou E, Kassambara L, Williams T, Wahl G, Millet P, Egwang TG. Human occult loiasis: field evaluation of a nested polymerase chain reaction assay for the detection of occult infection. Trop Med Int Health. 1998 Jun; 3(6):505-11. PMID: 9657514.
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    39. Touré FS, Egwang TG, Millet P, Bain O, Georges AJ, Wahl G. IgG4 serology of loiasis in three villages in an endemic area of south-eastern Gabon. Trop Med Int Health. 1998 Apr; 3(4):313-7. PMID: 9623933.
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    40. Touré FS, Bain O, Nerrienet E, Millet P, Wahl G, Toure Y, Doumbo O, Nicolas L, Georges AJ, McReynolds LA, Egwang TG. Detection of Loa loa-specific DNA in blood from occult-infected individuals. Exp Parasitol. 1997 Jul; 86(3):163-70. PMID: 9225766.
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    41. Baize S, Wahl G, Soboslay PT, Egwang TG, Georges AJ. T helper responsiveness in human Loa loa infection; defective specific proliferation and cytokine production by CD4+ T cells from microfilaraemic subjects compared with amicrofilaraemics. Clin Exp Immunol. 1997 May; 108(2):272-8. PMID: 9158097; PMCID: PMC1904664.
    42. Leroy E, Baize S, Wahl G, Egwang TG, Georges AJ. Experimental infection of a nonhuman primate with Loa loa induces transient strong immune activation followed by peripheral unresponsiveness of helper T cells. Infect Immun. 1997 May; 65(5):1876-82. PMID: 9125575; PMCID: PMC175234.
    43. Toure FS, Egwang TG, Wahl G, Millet P, Bain O, Georges AJ. Species-specific sequence in the repeat 3 region of the gene encoding a putative Loa loa allergen: a diagnostic tool for occult loiasis. Am J Trop Med Hyg. 1997 Jan; 56(1):57-60. PMID: 9063362.
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    44. Ajuh PM, Akue JP, Boutin P, Everaere S, Egwang TG. Loa loa: structural diversity of a 15-kDa repetitive antigen. Exp Parasitol. 1995 Sep; 81(2):145-53. PMID: 7556556.
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    45. Egwang TG, Duong TH, Nguiri C, Ngari P, Everaere S, Richard-Lenoble D, Gbakima AA, Kombila M. Evaluation of Onchocerca volvulus-specific IgG4 subclass serology as an index of onchocerciasis transmission potential of three Gabonese villages. Clin Exp Immunol. 1994 Dec; 98(3):401-7. PMID: 7994904; PMCID: PMC1534500.
    46. Ajuh PM, Egwang TG. Cloning of a cDNA encoding a putative nicotinic acetylcholine receptor subunit of the human filarial parasite Onchocerca volvulus. Gene. 1994 Jun 24; 144(1):127-9. PMID: 8026747.
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    47. Egwang TG, Nguiri C, Kombila M, Duong TH, Richard-Lenoble D. Elevated antifilarial IgG4 antibody levels in microfilaremic and microfilaridermic Gabonese adults and children. Am J Trop Med Hyg. 1993 Jul; 49(1):135-42. PMID: 8352386.
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    48. Egwang TG, Ajuh PM, Akue JP. Cloning and characterization of a Loa loa-specific repetitive DNA. Mol Biochem Parasitol. 1992 Dec; 56(2):189-96. PMID: 1484545.
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    49. Egwang TG, Kazura JW. The BALB/c mouse as a model for immunological studies of microfilariae-induced pulmonary eosinophilia. Am J Trop Med Hyg. 1990 Jul; 43(1):61-6. PMID: 2382764.
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    50. Pinder M, Leclerc A, Flockhart HA, Egwang TG. Macaca fascicularis, a nonpermissive host for the human filarial parasite Loa loa. J Parasitol. 1990 Jun; 76(3):373-6. PMID: 2352067.
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    51. Egwang TG, Dupont A, Leclerc A, Akué JP, Pinder M. Differential recognition of Loa loa antigens by sera of human subjects from a loiasis endemic zone. Am J Trop Med Hyg. 1989 Dec; 41(6):664-73. PMID: 2641644.
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    52. Egwang TG, Dupont A, Akué JP, Pinder M. Biochemical and immunochemical characterization of surface and excretory-secretory antigens of Loa loa microfilariae. Mol Biochem Parasitol. 1988 Dec; 31(3):251-61. PMID: 2464765.
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    53. Egwang TG, Akué JP, Dupont A, Pinder M. The identification and partial characterization of an immunodominant 29-31 kilodalton surface antigen expressed by adult worms of the human filaria Loa loa. Mol Biochem Parasitol. 1988 Dec; 31(3):263-72. PMID: 3221911.
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    54. Egwang TG, Kazura JW. Immunochemical characterization and biosynthesis of major antigens of iodo-bead surface-labeled Brugia malayi microfilariae. Mol Biochem Parasitol. 1987 Jan 15; 22(2-3):159-68. PMID: 3574345.
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    55. Egwang TG, Befus AD, Gauldie J. Activation of alveolar macrophages following infection with the parasitic nematode Nippostrongylus brasiliensis. Immunology. 1985 Mar; 54(3):581-8. PMID: 3882558; PMCID: PMC1453519.
    56. Egwang TG, Gauldie J, Befus D. Complement-dependent killing of Nippostrongylus brasiliensis infective larvae by rat alveolar macrophages. Clin Exp Immunol. 1984 Jan; 55(1):149-56. PMID: 6362933; PMCID: PMC1535800.
    57. Egwang TG, Gauldie J, Befus AD. Lack of specificity of the C3-opsonized zymosan reagent for the assay of membrane complement receptors. J Immunol Methods. 1983 Jul 15; 61(2):253-7. PMID: 6345679.
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