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Professor Simon Lawrence Croft

TitleProfessor of Parasitology
InstitutionLondon School of Hygiene and Tropical Medicine
AddressLondon WC1E 7HT
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Van Bocxlaer K, Gaukel E, Hauser D, Park SH, Schock S, Yardley V, Randolph R, Plattner JJ, Merchant T, Croft SL, Jacobs RT, Wring SA. Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles. Antimicrob Agents Chemother. 2018 May; 62(5). PMID: 29507073.
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    2. Wijnant GJ, Van Bocxlaer K, Yardley V, Harris A, Alavijeh M, Silva-Pedrosa R, Antunes S, Mauricio I, Murdan S, Croft SL. Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome® and AmBisome® in murine cutaneous leishmaniasis. Int J Parasitol Drugs Drug Resist. 2018 Apr 12; 8(2):223-228. PMID: 29673889.
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    3. Wijnant GJ, Van Bocxlaer K, Yardley V, Harris A, Murdan S, Croft SL. Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis. Antimicrob Agents Chemother. 2018 Mar; 62(3). PMID: 29263075.
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    4. Basilico N, Parapini S, Sparatore A, Romeo S, Misiano P, Vivas L, Yardley V, Croft SL, Habluetzel A, Lucantoni L, Renia L, Russell B, Suwanarusk R, Nosten F, Dondio G, Bigogno C, Jabes D, Taramelli D. In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. Molecules. 2017 Dec 01; 22(12). PMID: 29194347.
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    5. Wijnant GJ, Van Bocxlaer K, Yardley V, Murdan S, Croft SL. Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. Antimicrob Agents Chemother. 2017 08; 61(8). PMID: 28607026.
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    6. Burrell-Saward H, Harris AJ, de LaFlor R, Sallam H, Alavijeh MS, Ward TH, Croft SL. Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human African trypanosomiasis. Int J Antimicrob Agents. 2017 Aug; 50(2):203-209. PMID: 28552771.
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    7. Van Bocxlaer K, Yardley V, Murdan S, Croft SL. Drug permeation and barrier damage in Leishmania-infected mouse skin. J Antimicrob Chemother. 2016 06; 71(6):1578-85. PMID: 26903275.
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    8. Croft SL, Ward S. The Nobel Prize in Medicine 2015: Two drugs that changed global health. Sci Transl Med. 2015 Dec 02; 7(316):316ed14. PMID: 26631629.
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    9. Seifert K, Juhls C, Salguero FJ, Croft SL. Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. Antimicrob Agents Chemother. 2015 Sep; 59(9):5819-23. PMID: 26055371.
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    10. Riede O, Seifert K, Oswald D, Endmann A, Hock C, Winkler A, Salguero FJ, Schroff M, Croft SL, Juhls C. Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. Gene Ther. 2015 Aug; 22(8):628-35. PMID: 25871827.
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    11. Kaur H, Seifert K, Hawkes GE, Coumbarides GS, Alvar J, Croft SL. Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. Am J Trop Med Hyg. 2015 Jun; 92(6 Suppl):31-38. PMID: 25897058.
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    12. Burrell-Saward H, Rodgers J, Bradley B, Croft SL, Ward TH. A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. J Antimicrob Chemother. 2015 Feb; 70(2):510-7. PMID: 25298516.
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    13. Das S, Freier A, Boussoffara T, Das S, Oswald D, Losch FO, Selka M, Sacerdoti-Sierra N, Schönian G, Wiesmüller KH, Seifert K, Schroff M, Juhls C, Jaffe CL, Roy S, Das P, Louzir H, Croft SL, Modabber F, Walden P. Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. Sci Transl Med. 2014 Apr 30; 6(234):234ra56. PMID: 24786324.
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    14. Sanderson L, Yardley V, Croft SL. Activity of anti-cancer protein kinase inhibitors against Leishmania spp. J Antimicrob Chemother. 2014 Jul; 69(7):1888-91. PMID: 24668412.
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    15. Barrett MP, Croft SL. Emerging paradigms in anti-infective drug design. Parasitology. 2014 Jan; 141(1):1-7. PMID: 24401336.
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    16. McLatchie AP, Burrell-Saward H, Myburgh E, Lewis MD, Ward TH, Mottram JC, Croft SL, Kelly JM, Taylor MC. Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase. PLoS Negl Trop Dis. 2013 Nov; 7(11):e2571. PMID: 24278497.
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    17. Mohamed-Ahmed AH, Seifert K, Yardley V, Burrell-Saward H, Brocchini S, Croft SL. Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(a-Glutamic Acid) complex. Antimicrob Agents Chemother. 2013 Oct; 57(10):4608-14. PMID: 23796924.
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    18. Alvar J, Croft SL, Kaye P, Khamesipour A, Sundar S, Reed SG. Case study for a vaccine against leishmaniasis. Vaccine. 2013 Apr 18; 31 Suppl 2:B244-9. PMID: 23598489.
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    19. Mohamed-Ahmed AH, Les KA, Seifert K, Croft SL, Brocchini S. Noncovalent complexation of amphotericin-B with Poly(a-glutamic acid). Mol Pharm. 2013 Mar 04; 10(3):940-50. PMID: 23234235.
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    20. Mohamed-Ahmed AH, Brocchini S, Croft SL. Recent advances in development of amphotericin B formulations for the treatment of visceral leishmaniasis. Curr Opin Infect Dis. 2012 Dec; 25(6):695-702. PMID: 23147810.
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    21. Barrett MP, Croft SL. Management of trypanosomiasis and leishmaniasis. Br Med Bull. 2012; 104:175-96. PMID: 23137768.
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    22. Croft SL, Duparc S, Arbe-Barnes SJ, Craft JC, Shin CS, Fleckenstein L, Borghini-Fuhrer I, Rim HJ. Review of pyronaridine anti-malarial properties and product characteristics. Malar J. 2012 Aug 09; 11:270. PMID: 22877082.
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    23. Croft SL, Olliaro P. Leishmaniasis chemotherapy--challenges and opportunities. Clin Microbiol Infect. 2011 Oct; 17(10):1478-83. PMID: 21933306.
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    24. Staines HM, Croft SL, Horrocks PD. Developing novel strategies to prevent parasitic infections. Expert Rev Anti Infect Ther. 2011 Jul; 9(7):783-5. PMID: 21810050.
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    25. Seifert K, Munday J, Syeda T, Croft SL. In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. J Antimicrob Chemother. 2011 Apr; 66(4):850-4. PMID: 21393188.
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    26. Baschong W, Wittlin S, Inglis KA, Fairlamb AH, Croft SL, Kumar TR, Fidock DA, Brun R. Triclosan is minimally effective in rodent malaria models. Nat Med. 2011 Jan; 17(1):33-4; author reply 34-5. PMID: 21217674.
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    27. Wube AA, Bucar F, Gibbons S, Asres K, Rattray L, Croft SL. Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. Phytother Res. 2010 Oct; 24(10):1468-72. PMID: 20878696.
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    28. Yardley V, Gamarro F, Croft SL. Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine. Antimicrob Agents Chemother. 2010 Dec; 54(12):5356-8. PMID: 20837750.
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    29. Dujardin JC, González-Pacanowska D, Croft SL, Olesen OF, Späth GF. Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. Trends Parasitol. 2010 Aug; 26(8):395-403. PMID: 20538522.
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    30. Venkatesh G, Majid MI, Mansor SM, Nair NK, Croft SL, Navaratnam V. In vitro and in vivo evaluation of self-microemulsifying drug delivery system of buparvaquone. Drug Dev Ind Pharm. 2010 Jun; 36(6):735-45. PMID: 20136493.
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    31. Seifert K, Escobar P, Croft SL. In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. J Antimicrob Chemother. 2010 Mar; 65(3):508-11. PMID: 20089542.
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    32. Guglielmo S, Bertinaria M, Rolando B, Crosetti M, Fruttero R, Yardley V, Croft SL, Gasco A. A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. Eur J Med Chem. 2009 Dec; 44(12):5071-9. PMID: 19811859.
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    33. Luna KP, Hernández IP, Rueda CM, Zorro MM, Croft SL, Escobar P. In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica. 2009 Sep; 29(3):448-55. PMID: 20436996.
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    34. dos Santos DA, de C Braga PA, da Silva MF, Fernandes JB, Vieira PC, Magalhães AF, Magalhães EG, Marsaioli AJ, de S Moraes VR, Rattray L, Croft SL. Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues. J Pharm Pharmacol. 2009 Feb; 61(2):257-66. PMID: 19178775.
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    35. Gemma S, Campiani G, Butini S, Joshi BP, Kukreja G, Coccone SS, Bernetti M, Persico M, Nacci V, Fiorini I, Novellino E, Taramelli D, Basilico N, Parapini S, Yardley V, Croft S, Keller-Maerki S, Rottmann M, Brun R, Coletta M, Marini S, Guiso G, Caccia S, Fattorusso C. Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials. J Med Chem. 2009 Jan 22; 52(2):502-13. PMID: 19113955.
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    36. Croft SL. Kinetoplastida: new therapeutic strategies. Parasite. 2008 Sep; 15(3):522-7. PMID: 18814734.
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    37. Croft SL. PKDL--a drug related phenomenon? Indian J Med Res. 2008 Jul; 128(1):10-1. PMID: 18820352.
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    38. Venkatesh G, Majid MI, Ramanathan S, Mansor SM, Nair NK, Croft SL, Navaratnam V. Optimization and validation of RP-HPLC-UV method with solid-phase extraction for determination of buparvaquone in human and rabbit plasma: application to pharmacokinetic study. Biomed Chromatogr. 2008 May; 22(5):535-41. PMID: 18205140.
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    39. Nanayakkara NP, Ager AL, Bartlett MS, Yardley V, Croft SL, Khan IA, McChesney JD, Walker LA. Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. Antimicrob Agents Chemother. 2008 Jun; 52(6):2130-7. PMID: 18378716.
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    40. Vivas L, Rattray L, Stewart L, Bongard E, Robinson BL, Peters W, Croft SL. Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta Trop. 2008 Mar; 105(3):222-8. PMID: 18279817.
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    41. Seifert K, Lemke A, Croft SL, Kayser O. Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives. Antimicrob Agents Chemother. 2007 Dec; 51(12):4525-8. PMID: 17908944.
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    42. Haynes RK, Wong HN, Lee KW, Lung CM, Shek LY, Williams ID, Croft SL, Vivas L, Rattray L, Stewart L, Wong VK, Ko BC. Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. ChemMedChem. 2007 Oct; 2(10):1464-79. PMID: 17768731.
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    43. Blackie MA, Beagley P, Croft SL, Kendrick H, Moss JR, Chibale K. Metallocene-based antimalarials: an exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. Bioorg Med Chem. 2007 Oct 15; 15(20):6510-6. PMID: 17693090.
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    44. Seifert K, Pérez-Victoria FJ, Stettler M, Sánchez-Cañete MP, Castanys S, Gamarro F, Croft SL. Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. Int J Antimicrob Agents. 2007 Sep; 30(3):229-35. PMID: 17628445.
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    45. Modabber F, Buffet PA, Torreele E, Milon G, Croft SL. Consultative meeting to develop a strategy for treatment of cutaneous leishmaniasis. Institute Pasteur, Paris. 13-15 June, 2006. Kinetoplastid Biol Dis. 2007 Apr 24; 6:3. PMID: 17456237.
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    46. Vivas L, Rattray L, Stewart LB, Robinson BL, Fugmann B, Haynes RK, Peters W, Croft SL. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. J Antimicrob Chemother. 2007 Apr; 59(4):658-65. PMID: 17337512.
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    47. Garnier T, Mäntylä A, Järvinen T, Lawrence MJ, Brown MB, Croft SL. Topical buparvaquone formulations for the treatment of cutaneous leishmaniasis. J Pharm Pharmacol. 2007 Jan; 59(1):41-9. PMID: 17227619.
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    48. Venkatesh G, Ramanathan S, Mansor SM, Nair NK, Sattar MA, Croft SL, Navaratnam V. Development and validation of RP-HPLC-UV method for simultaneous determination of buparvaquone, atenolol, propranolol, quinidine and verapamil: a tool for the standardization of rat in situ intestinal permeability studies. J Pharm Biomed Anal. 2007 Mar 12; 43(4):1546-51. PMID: 17157469.
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    49. Gros L, Lorente SO, Jimenez CJ, Yardley V, Rattray L, Wharton H, Little S, Croft SL, Ruiz-Perez LM, Gonzalez-Pacanowska D, Gilbert IH. Evaluation of azasterols as anti-parasitics. J Med Chem. 2006 Oct 05; 49(20):6094-103. PMID: 17004723.
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    50. Croft SL, Engel J. Miltefosine--discovery of the antileishmanial activity of phospholipid derivatives. Trans R Soc Trop Med Hyg. 2006 Dec; 100 Suppl 1:S4-8. PMID: 16904717.
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    51. Gros L, Castillo-Acosta VM, Jiménez Jiménez C, Sealey-Cardona M, Vargas S, Manuel Estévez A, Yardley V, Rattray L, Croft SL, Ruiz-Perez LM, Urbina JA, Gilbert IH, González-Pacanowska D. New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. Antimicrob Agents Chemother. 2006 Aug; 50(8):2595-601. PMID: 16870747.
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    52. Garnier T, Brown MB, Lawrence MJ, Croft SL. In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. J Pharm Pharmacol. 2006 Aug; 58(8):1043-54. PMID: 16872550.
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    53. Berman J, Bryceson AD, Croft S, Engel J, Gutteridge W, Karbwang J, Sindermann H, Soto J, Sundar S, Urbina JA. Miltefosine: issues to be addressed in the future. Trans R Soc Trop Med Hyg. 2006 Dec; 100 Suppl 1:S41-4. PMID: 16750231.
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    54. Haynes RK, Fugmann B, Stetter J, Rieckmann K, Heilmann HD, Chan HW, Cheung MK, Lam WL, Wong HN, Croft SL, Vivas L, Rattray L, Stewart L, Peters W, Robinson BL, Edstein MD, Kotecka B, Kyle DE, Beckermann B, Gerisch M, Radtke M, Schmuck G, Steinke W, Wollborn U, Schmeer K, Römer A. Artemisone--a highly active antimalarial drug of the artemisinin class. Angew Chem Int Ed Engl. 2006 Mar 20; 45(13):2082-8. PMID: 16444785.
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    55. Croft SL, Seifert K, Yardley V. Current scenario of drug development for leishmaniasis. Indian J Med Res. 2006 Mar; 123(3):399-410. PMID: 16778319.
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    56. Pérez-Victoria FJ, Sánchez-Cañete MP, Seifert K, Croft SL, Sundar S, Castanys S, Gamarro F. Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. Drug Resist Updat. 2006 Feb-Apr; 9(1-2):26-39. PMID: 16814199.
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    57. Hudock MP, Sanz-Rodríguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepción JL, Yardley V, Croft SL, Urbina JA, Oldfield E. Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. J Med Chem. 2006 Jan 12; 49(1):215-23. PMID: 16392806.
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    58. Croft SL, Sundar S, Fairlamb AH. Drug resistance in leishmaniasis. Clin Microbiol Rev. 2006 Jan; 19(1):111-26. PMID: 16418526.
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    59. Seifert K, Croft SL. In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. Antimicrob Agents Chemother. 2006 Jan; 50(1):73-9. PMID: 16377670.
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    60. Alvar J, Croft S, Olliaro P. Chemotherapy in the treatment and control of leishmaniasis. Adv Parasitol. 2006; 61:223-74. PMID: 16735166.
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    61. Parveen S, Khan MO, Austin SE, Croft SL, Yardley V, Rock P, Douglas KT. Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide. J Med Chem. 2005 Dec 15; 48(25):8087-97. PMID: 16335933.
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    62. Gokhale NH, Shirisha K, Padhye SB, Croft SL, Kendrick HD, Mckee V. Metalloantimalarials: synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. Bioorg Med Chem Lett. 2006 Jan 15; 16(2):430-2. PMID: 16275074.
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    63. Croft SL. Public-private partnership: from there to here. Trans R Soc Trop Med Hyg. 2005 Oct; 99 Suppl 1:S9-14. PMID: 16087204.
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    64. Vivas L, Easton A, Kendrick H, Cameron A, Lavandera JL, Barros D, de las Heras FG, Brady RL, Croft SL. Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase. Exp Parasitol. 2005 Oct; 111(2):105-14. PMID: 16098967.
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    65. Lorente SO, Jimenez CJ, Gros L, Yardley V, de Luca-Fradley K, Croft SL, A Urbina J, Ruiz-Perez LM, Pacanowska DG, Gilbert IH. Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics. Bioorg Med Chem. 2005 Sep 15; 13(18):5435-53. PMID: 16046134.
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    66. Croft SL, Barrett MP, Urbina JA. Chemotherapy of trypanosomiases and leishmaniasis. Trends Parasitol. 2005 Nov; 21(11):508-12. PMID: 16150644.
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    67. Yardley V, Croft SL, De Doncker S, Dujardin JC, Koirala S, Rijal S, Miranda C, Llanos-Cuentas A, Chappuis F. The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. Am J Trop Med Hyg. 2005 Aug; 73(2):272-5. PMID: 16103588.
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    68. Wube AA, Bucar F, Asres K, Gibbons S, Rattray L, Croft SL. Antimalarial compounds from Kniphofia foliosa roots. Phytother Res. 2005 Jun; 19(6):472-6. PMID: 16114082.
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    69. Orenes Lorente S, Gómez R, Jiménez C, Cammerer S, Yardley V, de Luca-Fradley K, Croft SL, Ruiz Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. Bioorg Med Chem. 2005 May 16; 13(10):3519-29. PMID: 15848765.
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    70. Conners R, Schambach F, Read J, Cameron A, Sessions RB, Vivas L, Easton A, Croft SL, Brady RL. Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol Biochem Parasitol. 2005 Aug; 142(2):137-48. PMID: 15978953.
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    71. Onyeibor O, Croft SL, Dodson HI, Feiz-Haddad M, Kendrick H, Millington NJ, Parapini S, Phillips RM, Seville S, Shnyder SD, Taramelli D, Wright CW. Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. J Med Chem. 2005 Apr 07; 48(7):2701-9. PMID: 15801861.
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    72. Carrico D, Ohkanda J, Kendrick H, Yokoyama K, Blaskovich MA, Bucher CJ, Buckner FS, Van Voorhis WC, Chakrabarti D, Croft SL, Gelb MH, Sebti SM, Hamilton AD. In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. Bioorg Med Chem. 2004 Dec 15; 12(24):6517-26. PMID: 15556768.
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    73. Grant KM, Dunion MH, Yardley V, Skaltsounis AL, Marko D, Eisenbrand G, Croft SL, Meijer L, Mottram JC. Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity. Antimicrob Agents Chemother. 2004 Aug; 48(8):3033-42. PMID: 15273118.
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    74. Lorente SO, Rodrigues JC, Jiménez Jiménez C, Joyce-Menekse M, Rodrigues C, Croft SL, Yardley V, de Luca-Fradley K, Ruiz-Pérez LM, Urbina J, de Souza W, González Pacanowska D, Gilbert IH. Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. Antimicrob Agents Chemother. 2004 Aug; 48(8):2937-50. PMID: 15273104.
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    75. Mäntylä A, Rautio J, Nevalainen T, Vepsälainen J, Juvonen R, Kendrick H, Garnier T, Croft SL, Järvinen T. Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. Bioorg Med Chem. 2004 Jul 01; 12(13):3497-502. PMID: 15186834.
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    76. Cottrell DM, Capers J, Salem MM, DeLuca-Fradley K, Croft SL, Werbovetz KA. Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4-oxadiazoles. Bioorg Med Chem. 2004 Jun 01; 12(11):2815-24. PMID: 15142541.
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    77. Fidock DA, Rosenthal PJ, Croft SL, Brun R, Nwaka S. Antimalarial drug discovery: efficacy models for compound screening. Nat Rev Drug Discov. 2004 Jun; 3(6):509-20. PMID: 15173840.
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    78. Cameron A, Read J, Tranter R, Winter VJ, Sessions RB, Brady RL, Vivas L, Easton A, Kendrick H, Croft SL, Barros D, Lavandera JL, Martin JJ, Risco F, García-Ochoa S, Gamo FJ, Sanz L, Leon L, Ruiz JR, Gabarró R, Mallo A, Gómez de las Heras F. Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. J Biol Chem. 2004 Jul 23; 279(30):31429-39. PMID: 15117937.
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    79. Jung M, Lee K, Jung H, Kendrick H, Yardley V, Croft SL. Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives. Bioorg Med Chem Lett. 2004 Apr 19; 14(8):2001-3. PMID: 15050646.
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    80. Bailey NJ, Wang Y, Sampson J, Davis W, Whitcombe I, Hylands PJ, Croft SL, Holmes E. Prediction of anti-plasmodial activity of Artemisia annua extracts: application of 1H NMR spectroscopy and chemometrics. J Pharm Biomed Anal. 2004 Apr 01; 35(1):117-26. PMID: 15030886.
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    81. Haynes RK, Ho WY, Chan HW, Fugmann B, Stetter J, Croft SL, Vivas L, Peters W, Robinson BL. Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity. Angew Chem Int Ed Engl. 2004 Mar 05; 43(11):1381-5. PMID: 15368412.
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    82. Ohkanda J, Buckner FS, Lockman JW, Yokoyama K, Carrico D, Eastman R, de Luca-Fradley K, Davies W, Croft SL, Van Voorhis WC, Gelb MH, Sebti SM, Hamilton AD. Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents. J Med Chem. 2004 Jan 15; 47(2):432-45. PMID: 14711313.
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    83. Nan A, Croft SL, Yardley V, Ghandehari H. Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis. J Control Release. 2004 Jan 08; 94(1):115-27. PMID: 14684276.
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    84. Ghosh S, Chan JM, Lea CR, Meints GA, Lewis JC, Tovian ZS, Flessner RM, Loftus TC, Bruchhaus I, Kendrick H, Croft SL, Kemp RG, Kobayashi S, Nozaki T, Oldfield E. Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. J Med Chem. 2004 Jan 01; 47(1):175-87. PMID: 14695831.
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    85. del Rayo Camacho M, Phillipson JD, Croft SL, Yardley V, Solis PN. In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins. Planta Med. 2004 Jan; 70(1):70-2. PMID: 14765298.
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    86. Mäntylä A, Garnier T, Rautio J, Nevalainen T, Vepsälainen J, Koskinen A, Croft SL, Järvinen T. Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone. J Med Chem. 2004 Jan 01; 47(1):188-95. PMID: 14695832.
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    87. Camacho Md, Phillipson JD, Croft SL, Solis PN, Marshall SJ, Ghazanfar SA. Screening of plant extracts for antiprotozoal and cytotoxic activities. J Ethnopharmacol. 2003 Dec; 89(2-3):185-91. PMID: 14611881.
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    88. Larabi M, Yardley V, Loiseau PM, Appel M, Legrand P, Gulik A, Bories C, Croft SL, Barratt G. Toxicity and antileishmanial activity of a new stable lipid suspension of amphotericin B. Antimicrob Agents Chemother. 2003 Dec; 47(12):3774-9. PMID: 14638481.
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    89. Pez D, Leal I, Zuccotto F, Boussard C, Brun R, Croft SL, Yardley V, Ruiz Perez LM, Gonzalez Pacanowska D, Gilbert IH. 2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase. Bioorg Med Chem. 2003 Nov 03; 11(22):4693-711. PMID: 14556785.
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    90. Ren H, Grady S, Banghart M, Moulthrop JS, Kendrick H, Yardley V, Croft SL, Moyna G. Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. Eur J Med Chem. 2003 Nov-Dec; 38(11-12):949-57. PMID: 14642327.
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    91. Croft SL, Coombs GH. Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. Trends Parasitol. 2003 Nov; 19(11):502-8. PMID: 14580961.
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    92. Magaraci F, Jimenez CJ, Rodrigues C, Rodrigues JC, Braga MV, Yardley V, de Luca-Fradley K, Croft SL, de Souza W, Ruiz-Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. J Med Chem. 2003 Oct 23; 46(22):4714-27. PMID: 14561091.
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    93. Seifert K, Matu S, Javier Pérez-Victoria F, Castanys S, Gamarro F, Croft SL. Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). Int J Antimicrob Agents. 2003 Oct; 22(4):380-7. PMID: 14522101.
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    94. Sindermann H, Croft SL, Engel KR, Bommer W, Eibl HJ, Unger C, Engel J. Miltefosine (Impavido): the first oral treatment against leishmaniasis. Med Microbiol Immunol. 2004 Nov; 193(4):173-80. PMID: 14513375.
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    95. Ramírez I, Carabot A, Meléndez P, Carmona J, Jimenez M, Patel AV, Crabb TA, Blunden G, Cary PD, Croft SL, Costa M. Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. Phytochemistry. 2003 Sep; 64(2):645-7. PMID: 12943789.
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    96. Bal G, Van der Veken P, Antonov D, Lambeir AM, Grellier P, Croft SL, Augustyns K, Haemers A. Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. Bioorg Med Chem Lett. 2003 Sep 01; 13(17):2875-8. PMID: 14611847.
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    97. Liu M, Wilairat P, Croft SL, Tan AL, Go ML. Structure-activity relationships of antileishmanial and antimalarial chalcones. Bioorg Med Chem. 2003 Jul 03; 11(13):2729-38. PMID: 12788347.
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    98. Gokhale NH, Padhye SB, Croft SL, Kendrick HD, Davies W, Anson CE, Powell AK. Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. J Inorg Biochem. 2003 Jul 01; 95(4):249-58. PMID: 12818795.
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    99. Croft SL, Vivas L, Brooker S. Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis. East Mediterr Health J. 2003 Jul; 9(4):518-33. PMID: 15748049.
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    100. Kayser O, Kiderlen AF, Croft SL. Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). Acta Trop. 2003 Apr; 86(1):105-7. PMID: 12711109.
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    101. Kayser O, Olbrich C, Yardley V, Kiderlen AF, Croft SL. Formulation of amphotericin B as nanosuspension for oral administration. Int J Pharm. 2003 Mar 18; 254(1):73-5. PMID: 12615413.
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    102. Kayser O, Kiderlen AF, Croft SL. Natural products as antiparasitic drugs. Parasitol Res. 2003 Jun; 90 Suppl 2:S55-62. PMID: 12937967.
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    103. Davies CR, Kaye P, Croft SL, Sundar S. Leishmaniasis: new approaches to disease control. BMJ. 2003 Feb 15; 326(7385):377-82. PMID: 12586674.
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    104. Croft SL, Seifert K, Duchêne M. Antiprotozoal activities of phospholipid analogues. Mol Biochem Parasitol. 2003 Feb; 126(2):165-72. PMID: 12615315.
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    105. Chauvière G, Bouteille B, Enanga B, de Albuquerque C, Croft SL, Dumas M, Périé J. Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. J Med Chem. 2003 Jan 30; 46(3):427-40. PMID: 12540242.
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    106. Kayser O, Olbrich C, Croft SL, Kiderlen AF. Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. Parasitol Res. 2003 Jun; 90 Suppl 2:S63-70. PMID: 12937968.
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    107. Jung M, Lee K, Kendrick H, Robinson BL, Croft SL. Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid. J Med Chem. 2002 Oct 24; 45(22):4940-4. PMID: 12383020.
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    108. del Rayo Camacho M, Phillipson JD, Croft SL, Marley D, Kirby GC, Warhurst DC. Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. J Nat Prod. 2002 Oct; 65(10):1457-61. PMID: 12398543.
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    109. del Rayo Camacho M, Phillipson JD, Croft SL, Rock P, Marshall SJ, Schiff PL. In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. Phytother Res. 2002 Aug; 16(5):432-6. PMID: 12203262.
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    110. Guerin PJ, Olliaro P, Sundar S, Boelaert M, Croft SL, Desjeux P, Wasunna MK, Bryceson AD. Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. Lancet Infect Dis. 2002 Aug; 2(8):494-501. PMID: 12150849.
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    111. Martin MB, Sanders JM, Kendrick H, de Luca-Fradley K, Lewis JC, Grimley JS, Van Brussel EM, Olsen JR, Meints GA, Burzynska A, Kafarski P, Croft SL, Oldfield E. Activity of bisphosphonates against Trypanosoma brucei rhodesiense. J Med Chem. 2002 Jul 04; 45(14):2904-14. PMID: 12086478.
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    112. Muriithi MW, Abraham WR, Addae-Kyereme J, Scowen I, Croft SL, Gitu PM, Kendrick H, Njagi EN, Wright CW. Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. J Nat Prod. 2002 Jul; 65(7):956-9. PMID: 12141852.
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    113. Garnier T, Croft SL. Topical treatment for cutaneous leishmaniasis. Curr Opin Investig Drugs. 2002 Apr; 3(4):538-44. PMID: 12090720.
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    114. Croft SL, Yardley V, Kendrick H. Drug sensitivity of Leishmania species: some unresolved problems. Trans R Soc Trop Med Hyg. 2002 Apr; 96 Suppl 1:S127-9. PMID: 12055825.
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    115. Yardley V, Khan AA, Martin MB, Slifer TR, Araujo FG, Moreno SN, Docampo R, Croft SL, Oldfield E. In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrob Agents Chemother. 2002 Mar; 46(3):929-31. PMID: 11850291.
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    116. Escobar P, Matu S, Marques C, Croft SL. Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. Acta Trop. 2002 Feb; 81(2):151-7. PMID: 11801222.
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    117. Croft SL, Yardley V. Chemotherapy of leishmaniasis. Curr Pharm Des. 2002; 8(4):319-42. PMID: 11860369.
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    118. Nan A, Nanayakkara NP, Walker LA, Yardley V, Croft SL, Ghandehari H. N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. J Control Release. 2001 Dec 13; 77(3):233-43. PMID: 11733091.
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    119. Croft SL. Monitoring drug resistance in leishmaniasis. Trop Med Int Health. 2001 Nov; 6(11):899-905. PMID: 11703844.
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    120. Asres K, Bucar F, Knauder E, Yardley V, Kendrick H, Croft SL. In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. Phytother Res. 2001 Nov; 15(7):613-7. PMID: 11746844.
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    121. Chibale K, Haupt H, Kendrick H, Yardley V, Saravanamuthu A, Fairlamb AH, Croft SL. Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorg Med Chem Lett. 2001 Oct 08; 11(19):2655-7. PMID: 11551771.
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    122. Wright CW, Addae-Kyereme J, Breen AG, Brown JE, Cox MF, Croft SL, Gökçek Y, Kendrick H, Phillips RM, Pollet PL. Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. J Med Chem. 2001 Sep 13; 44(19):3187-94. PMID: 11543688.
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    123. Daunes S, D'Silva C, Kendrick H, Yardley V, Croft SL. QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives. J Med Chem. 2001 Aug 30; 44(18):2976-83. PMID: 11520206.
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    124. Ren H, Grady S, Gamenara D, Heinzen H, Moyna P, Croft SL, Kendrick H, Yardley V, Moyna G. Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. Bioorg Med Chem Lett. 2001 Jul 23; 11(14):1851-4. PMID: 11459645.
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    125. Addae-Kyereme J, Croft SL, Kendrick H, Wright CW. Antiplasmodial activities of some Ghanaian plants traditionally used for fever/malaria treatment and of some alkaloids isolated from Pleiocarpa mutica; in vivo antimalarial activity of pleiocarpine. J Ethnopharmacol. 2001 Jun; 76(1):99-103. PMID: 11378289.
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    126. Escobar P, Yardley V, Croft SL. Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. Antimicrob Agents Chemother. 2001 Jun; 45(6):1872-5. PMID: 11353640.
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    127. Luque-Ortega JR, Rivero-Lezcano OM, Croft SL, Rivas L. In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolism. Antimicrob Agents Chemother. 2001 Apr; 45(4):1121-5. PMID: 11257025.
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    128. Ohkanda J, Lockman JW, Yokoyama K, Gelb MH, Croft SL, Kendrick H, Harrell MI, Feagin JE, Blaskovich MA, Sebti SM, Hamilton AD. Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. Bioorg Med Chem Lett. 2001 Mar 26; 11(6):761-4. PMID: 11277514.
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    129. Murray PJ, Kranz M, Ladlow M, Taylor S, Berst F, Holmes AB, Keavey KN, Jaxa-Chamiec A, Seale PW, Stead P, Upton RJ, Croft SL, Clegg W, Elsegood MR. The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. Bioorg Med Chem Lett. 2001 Mar 26; 11(6):773-6. PMID: 11277517.
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    130. Martin MB, Grimley JS, Lewis JC, Heath HT, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SN, Docampo R, Croft SL, Oldfield E. Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. J Med Chem. 2001 Mar 15; 44(6):909-16. PMID: 11300872.
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    131. Salmon-Chemin L, Buisine E, Yardley V, Kohler S, Debreu MA, Landry V, Sergheraert C, Croft SL, Krauth-Siegel RL, Davioud-Charvet E. 2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity. J Med Chem. 2001 Feb 15; 44(4):548-65. PMID: 11170645.
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    132. del Rayo Camacho M, Phillipson JD, Croft SL, Kirby GC, Warhurst DC, Solis PN. Terpenoids from Guarea rhophalocarpa. Phytochemistry. 2001 Jan; 56(2):203-10. PMID: 11219815.
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    133. Kayser O, Kiderlen AF, Laatsch H, Croft SL. In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones. Acta Trop. 2000 Dec 01; 77(3):307-14. PMID: 11114393.
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    134. Barata LE, Santos LS, Ferri PH, Phillipson JD, Paine A, Croft SL. Anti-leishmanial activity of neolignans from Virola species and synthetic analogues. Phytochemistry. 2000 Nov; 55(6):589-95. PMID: 11130669.
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    135. Kayser O, Kiderlen AF, Laatsch H, Croft SL. In vitro leishmanicidal activity of monomeric and dimeric naphthoquinones. Acta Trop. 2000 Sep 18; 76(2):131-8. PMID: 10936572.
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    136. Weiss CR, Moideen SV, Croft SL, Houghton PJ. Activity of extracts and isolated naphthoquinones from Kigelia pinnata against Plasmodium falciparum. J Nat Prod. 2000 Sep; 63(9):1306-9. PMID: 11000047.
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    137. Khan MO, Austin SE, Chan C, Yin H, Marks D, Vaghjiani SN, Kendrick H, Yardley V, Croft SL, Douglas KT. Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines. J Med Chem. 2000 Aug 10; 43(16):3148-56. PMID: 10956223.
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    138. Chibale K, Visser M, Yardley V, Croft SL, Fairlamb AH. Synthesis and evaluation of 9,9-dimethylxanthene tricyclics against trypanothione reductase, Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani. Bioorg Med Chem Lett. 2000 Jun 05; 10(11):1147-50. PMID: 10866368.
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    139. Khabnadideh S, Tan CL, Croft SL, Kendrick H, Yardley V, Gilbert IH. Squalamine analogues as potential anti-trypanosomal and anti-leishmanial compounds. Bioorg Med Chem Lett. 2000 Jun 05; 10(11):1237-9. PMID: 10866389.
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    140. Camacho MR, Mata R, Castaneda P, Kirby GC, Warhurst DC, Croft SL, Phillipson JD. Bioactive compounds from Celaenodendron mexicanum. Planta Med. 2000 Jun; 66(5):463-8. PMID: 10909269.
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    141. Camacho MR, Kirby GC, Warhurst DC, Croft SL, Phillipson JD. Oxoaporphine alkaloids and quinones from Stephania dinklagei and evaluation of their antiprotozoal activities. Planta Med. 2000 Jun; 66(5):478-80. PMID: 10909274.
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    142. Smith AC, Yardley V, Rhodes J, Croft SL. Activity of the novel immunomodulatory compound tucaresol against experimental visceral leishmaniasis. Antimicrob Agents Chemother. 2000 Jun; 44(6):1494-8. PMID: 10817698.
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    143. Davidson RN, Yardley V, Croft SL, Konecny P, Benjamin N. A topical nitric oxide-generating therapy for cutaneous leishmaniasis. Trans R Soc Trop Med Hyg. 2000 May-Jun; 94(3):319-22. PMID: 10975011.
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    144. Yardley V, Croft SL. A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis. Int J Antimicrob Agents. 2000 Feb; 13(4):243-8. PMID: 10755238.
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    145. Blumenstiel K, Schöneck R, Yardley V, Croft SL, Krauth-Siegel RL. Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase. Biochem Pharmacol. 1999 Dec 01; 58(11):1791-9. PMID: 10571254.
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    146. Ali BR, Pal A, Croft SL, Taylor RJ, Field MC. The farnesyltransferase inhibitor manumycin A is a novel trypanocide with a complex mode of action including major effects on mitochondria. Mol Biochem Parasitol. 1999 Oct 25; 104(1):67-80. PMID: 10589982.
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    147. Chowdhury SF, Villamor VB, Guerrero RH, Leal I, Brun R, Croft SL, Goodman JM, Maes L, Ruiz-Perez LM, Pacanowska DG, Gilbert IH. Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase. J Med Chem. 1999 Oct 21; 42(21):4300-12. PMID: 10543874.
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    149. Moideen SV, Houghton PJ, Rock P, Croft SL, Aboagye-Nyame F. Activity of extracts and naphthoquinones from Kigelia pinnata against Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. Planta Med. 1999 Aug; 65(6):536-40. PMID: 10483374.
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    150. Kayser O, Croft SL, Kolodziej H. [Chemotherapy of leishmaniasis and human trypanosomiasis: status and new developments]. Pharm Unserer Zeit. 1999 Jul; 28(4):177-85. PMID: 10443145.
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    151. Lowe G, Droz AS, Vilaivan T, Weaver GW, Tweedale L, Pratt JM, Rock P, Yardley V, Croft SL. Cytotoxicity of (2,2':6',2''-terpyridine)platinum(II) complexes to Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei. J Med Chem. 1999 Mar 25; 42(6):999-1006. PMID: 10090783.
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    152. Croft SL. Pharmacological approaches to antitrypanosomal chemotherapy. Mem Inst Oswaldo Cruz. 1999 Mar-Apr; 94(2):215-20. PMID: 10224531.
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    154. Field H, Ali BR, Sherwin T, Gull K, Croft SL, Field MC. TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells. J Cell Sci. 1999 Jan; 112 ( Pt 2):147-56. PMID: 9858468.
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    155. Vexenat JA, Croft SL, Furtado Campos JH, Miles MA. Failure of buparvaquone (Butalex) in the treatment of canine visceral leishmaniosis. Vet Parasitol. 1998 May; 77(1):71-3. PMID: 9652385.
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    156. Tovar J, Cunningham ML, Smith AC, Croft SL, Fairlamb AH. Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: effect on parasite intracellular survival. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5311-6. PMID: 9560272.
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    157. Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs. J Med Chem. 1998 Jan 15; 41(2):148-56. PMID: 9457238.
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    158. Gamage SA, Figgitt DP, Wojcik SJ, Ralph RK, Ransijn A, Mauel J, Yardley V, Snowdon D, Croft SL, Denny WA. Structure-activity relationships for the antileishmanial and antitrypanosomal activities of 1'-substituted 9-anilinoacridines. J Med Chem. 1997 Aug 01; 40(16):2634-42. PMID: 9258370.
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    159. Yardley V, Croft SL. Activity of liposomal amphotericin B against experimental cutaneous leishmaniasis. Antimicrob Agents Chemother. 1997 Apr; 41(4):752-6. PMID: 9087483.
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    163. Leite VH, Croft SL. Hepatic extracellular matrix in BALB/c mice infected with Leishmania donovani. Int J Exp Pathol. 1996 Aug; 77(4):181-90. PMID: 8943737.
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    164. Bacchi CJ, Brun R, Croft SL, Alicea K, Bühler Y. In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors. Antimicrob Agents Chemother. 1996 Jun; 40(6):1448-53. PMID: 8726018.
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    166. Elueze EI, Croft SL, Warhurst DC. Activity of pyronaridine and mepacrine against twelve strains of Plasmodium falciparum in vitro. J Antimicrob Chemother. 1996 Mar; 37(3):511-8. PMID: 9182108.
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    167. Chan C, Yin H, Garforth J, McKie JH, Jaouhari RA, Douglas KT, Fairlamb AH, Croft SL. Inhibitors of trypanothione reductase as potential antitrypanosomal drugs. Biochem Soc Trans. 1995 Nov; 23(4):511S. PMID: 8654696.
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    168. Neal RA, Allen S, McCoy N, Olliaro P, Croft SL. The sensitivity of Leishmania species to aminosidine. J Antimicrob Chemother. 1995 May; 35(5):577-84. PMID: 7592170.
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    169. al Jaser M, el-Yazigi A, Kojan M, Croft SL. Skin uptake, distribution, and elimination of antimony following administration of sodium stibogluconate to patients with cutaneous leishmaniasis. Antimicrob Agents Chemother. 1995 Feb; 39(2):516-9. PMID: 7726524.
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    173. Evans AT, Croft SL. Antileishmanial actions of tricyclic neuroleptics appear to lack structural specificity. Biochem Pharmacol. 1994 Aug 03; 48(3):613-6. PMID: 7915114.
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    174. Neal RA, Murphy AG, Olliaro P, Croft SL. Aminosidine ointments for the treatment of experimental cutaneous leishmaniasis. Trans R Soc Trop Med Hyg. 1994 Mar-Apr; 88(2):223-5. PMID: 8036682.
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    175. Adosraku RK, Anderson MM, Anderson GJ, Choi G, Croft SL, Yardley V, Phillipson JD, Gibbons WA. Proton NMR lipid profile of Leishmania donovani promastigotes. Mol Biochem Parasitol. 1993 Dec; 62(2):251-62. PMID: 8139618.
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    177. Davidson RN, Croft SL. Recent advances in the treatment of visceral leishmaniasis. Trans R Soc Trop Med Hyg. 1993 Mar-Apr; 87(2):130-1, 141. PMID: 8393221.
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    178. Croft SL, Hogg J, Gutteridge WE, Hudson AT, Randall AW. The activity of hydroxynaphthoquinones against Leishmania donovani. J Antimicrob Chemother. 1992 Dec; 30(6):827-32. PMID: 1289357.
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    179. Gebre-Hiwot A, Tadesse G, Croft SL, Frommel D. An in vitro model for screening antileishmanial drugs: the human leukaemia monocyte cell line, THP-1. Acta Trop. 1992 Aug; 51(3-4):237-45. PMID: 1359751.
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    180. Croft SL, Neal RA, Craciunescu DG, Certad-Fombona G. The activity of platinum, iridium and rhodium drug complexes against Leishmania donovani. Trop Med Parasitol. 1992 Mar; 43(1):24-8. PMID: 1598504.
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    181. Croft SL, Davidson RN, Thornton EA. Liposomal amphotericin B in the treatment of visceral leishmaniasis. J Antimicrob Chemother. 1991 Oct; 28 Suppl B:111-8. PMID: 1778888.
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    182. Lang T, Warburg A, Sacks DL, Croft SL, Lane RP, Blackwell JM. Transmission and scanning EM-immunogold labeling of Leishmania major lipophosphoglycan in the sandfly Phlebotomus papatasi. Eur J Cell Biol. 1991 Aug; 55(2):362-72. PMID: 1935998.
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    183. Davidson RN, Croft SL, Scott A, Maini M, Moody AH, Bryceson AD. Liposomal amphotericin B in drug-resistant visceral leishmaniasis. Lancet. 1991 May 04; 337(8749):1061-2. PMID: 1673494.
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    184. Evans AT, Croft SL, Peters W, Neal RA. Antileishmanial effects of clofazimine and other antimycobacterial agents. Ann Trop Med Parasitol. 1989 Oct; 83(5):447-54. PMID: 2619361.
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    185. Evans AT, Croft SL, Peters W, Neal RA. Hydrazide antidepressants possess novel antileishmanial activity in vitro and in vivo. Ann Trop Med Parasitol. 1989 Feb; 83(1):19-24. PMID: 2596901.
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    186. Croft SL. Recent developments in the chemotherapy of leishmaniasis. Trends Pharmacol Sci. 1988 Oct; 9(10):376-81. PMID: 3078072.
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    187. Croft SL, Walker JJ, Gutteridge WE. Screening of drugs for rapid activity against Trypanosoma cruzi trypomastigotes in vitro. Trop Med Parasitol. 1988 Jun; 39(2):145-8. PMID: 3051293.
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    188. Liew FY, Schmidt JA, Liu DS, Millott SM, Scott MT, Dhaliwal JS, Croft SL. Suppressive substance produced by T cells from mice chronically infected with Trypanosoma cruzi. II. Partial biochemical characterization. J Immunol. 1988 Feb 01; 140(3):969-73. PMID: 3123553.
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    189. Croft SL, Dye C, Kahl LP. Leishmaniasis: the first centenary (1885-1985) new strategies for control. Parasitol Today. 1988 Feb; 4(2):51-3. PMID: 15463038.
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    190. Evans AT, Croft SL, Peters W. Failure of chlorpromazine or amitriptyline ointments to influence the course of experimental cutaneous leishmaniasis. Trans R Soc Trop Med Hyg. 1988; 82(2):226. PMID: 3188147.
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    191. Croft SL, Hogg J. Limited activity of bacterial DNA topoisomerase II inhibitors against Leishmania donovani and Trypanosoma cruzi amastigotes in vitro. Trans R Soc Trop Med Hyg. 1988; 82(6):856. PMID: 2855767.
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    192. Liew FY, Scott MT, Liu DS, Croft SL. Suppressive substance produced by T cells from mice chronically infected with Trypanosoma cruzi. I. Preferential inhibition of the induction of delayed-type hypersensitivity. J Immunol. 1987 Oct 01; 139(7):2452-7. PMID: 2958550.
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    193. Croft SL, Neal RA, Pendergast W, Chan JH. The activity of alkyl phosphorylcholines and related derivatives against Leishmania donovani. Biochem Pharmacol. 1987 Aug 15; 36(16):2633-6. PMID: 3606662.
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    194. Hammond DJ, Croft SL, Hogg J, Gutteridge WE. A strategy for the prevention of the transmission of Chagas' disease during blood transfusion. Acta Trop. 1986 Dec; 43(4):367-78. PMID: 2882664.
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    195. Dirie MF, Croft SL, Molyneux DH. Morphological changes of Trypanosoma vivax in mice. Vet Parasitol. 1986 Jan; 19(1-2):23-7. PMID: 3962159.
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    196. Croft SL, Evans AT, Neal RA. The activity of plumbagin and other electron carriers against Leishmania donovani and Leishmania mexicana amazonensis. Ann Trop Med Parasitol. 1985 Dec; 79(6):651-3. PMID: 3834847.
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    197. Neal RA, Croft SL, Nelson DJ. Anti-leishmanial effect of allopurinol ribonucleoside and the related compounds, allopurinol, thiopurinol, thiopurinol ribonucleoside, and of formycin B, sinefungin and the lepidine WR6026. Trans R Soc Trop Med Hyg. 1985; 79(1):122-8. PMID: 3992630.
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    198. Croft SL, Neal RA. The effect of allopurinol ribonucleoside and formycin B on Trypanosoma cruzi infections in mice. Trans R Soc Trop Med Hyg. 1985; 79(4):517-8. PMID: 3936241.
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    199. Croft SL, Kuzoe FA, Ryan L, Molyneux DH. Trypanosome infection rates of Glossina spp. (Diptera: Glossinidae) in transitional forest-savanna near Bouaflé, Ivory Coast. Tropenmed Parasitol. 1984 Dec; 35(4):247-50. PMID: 6098057.
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    200. Neal RA, Croft SL. An in-vitro system for determining the activity of compounds against the intracellular amastigote form of Leishmania donovani. J Antimicrob Chemother. 1984 Nov; 14(5):463-75. PMID: 6096347.
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    201. Croft SL, East JS, Molyneux DH. Anti-trypanosomal factor in the haemolymph of Glossina. Acta Trop. 1982 Dec; 39(4):293-302. PMID: 6187195.
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    202. Ryan L, Küpper W, Croft SL, Molyneux DH, Clair M. Differences in rates of acquisition of trypanosome infections between Glossina species in the field. Ann Soc Belg Med Trop. 1982 Dec; 62(4):291-300. PMID: 6301390.
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    203. Croft SL, Neame KD, Homewood CA. Accumulation of [125Sb]sodium stibogluconate by Leishmania mexicana amazonensis and Leishmania donovani in vitro. Comp Biochem Physiol C. 1981; 68C(1):95-8. PMID: 6108831.
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    204. Croft SL, Chance ML, Gardener PJ. Ultrastructural and biochemical characterization of stocks of Endotrypanum. Ann Trop Med Parasitol. 1980 Dec; 74(6):585-9. PMID: 7458462.
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    205. Croft SL, Molyneux DH. Studies on the ultrastructure, virus-like particles and infectivity of Leishmania hertigi. Ann Trop Med Parasitol. 1979 Jun; 73(3):213-26. PMID: 496473.
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    206. Croft SL, Schnur LF, Chance ML. The morphological, biochemical and serological characterization of strains of Leishmania hertigi from Panama and Brazil and their differentiation. Ann Trop Med Parasitol. 1978 Feb; 72(1):93-4. PMID: 655741.
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    207. Hommel M, Croft SL. Proceedings: A trypanosomatid parasite of laboratory-bred Culicoides variipennis. Trans R Soc Trop Med Hyg. 1975; 69(4):431. PMID: 1216306.
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