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Dr Peter Andrew Winstanley

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bell DJ, Nyirongo SK, Mukaka M, Molyneux ME, Winstanley PA, Ward SA. Population pharmacokinetics of sulfadoxine and pyrimethamine in Malawian children with malaria. Clin Pharmacol Ther. 2011 Feb; 89(2):268-75. PMID: 21191379.
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    2. Tiono AB, Dicko A, Ndububa DA, Agbenyega T, Pitmang S, Awobusuyi J, Pamba A, Duparc S, Goh LE, Harrell E, Carter N, Ward SA, Greenwood B, Winstanley PA. Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg. 2009 Dec; 81(6):969-78. PMID: 19996424.
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    3. Aponte JJ, Schellenberg D, Egan A, Breckenridge A, Carneiro I, Critchley J, Danquah I, Dodoo A, Kobbe R, Lell B, May J, Premji Z, Sanz S, Sevene E, Soulaymani-Becheikh R, Winstanley P, Adjei S, Anemana S, Chandramohan D, Issifou S, Mockenhaupt F, Owusu-Agyei S, Greenwood B, Grobusch MP, Kremsner PG, Macete E, Mshinda H, Newman RD, Slutsker L, Tanner M, Alonso P, Menendez C. Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials. Lancet. 2009 Oct 31; 374(9700):1533-42. PMID: 19765816.
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    4. Janha RE, Sisay-Joof F, Hamid-Adiamoh M, Worwui A, Chapman HL, Opara H, Dunyo S, Milligan P, Rockett K, Winstanley P, Pirmohamed M, Miller AK, Conway DJ, Walton RT. Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians. Pharmacogenomics. 2009 Sep; 10(9):1423-31. PMID: 19761366; PMCID: PMC3870622.
    5. Bell DJ, Wootton D, Mukaka M, Montgomery J, Kayange N, Chimpeni P, Hughes DA, Molyneux ME, Ward SA, Winstanley PA, Lalloo DG. Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. Malar J. 2009 Aug 26; 8:204. PMID: 19709418; PMCID: PMC2744923.
    6. Premji Z, Umeh RE, Owusu-Agyei S, Esamai F, Ezedinachi EU, Oguche S, Borrmann S, Sowunmi A, Duparc S, Kirby PL, Pamba A, Kellam L, Guiguemdé R, Greenwood B, Ward SA, Winstanley PA. Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria. PLoS One. 2009 Aug 19; 4(8):e6682. PMID: 19690618; PMCID: PMC2724683.
    7. Miller AK, Bandyopadhyay N, Wootton DG, Duparc S, Kirby PL, Winstanley PA, Ward SA. Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria. Eur J Clin Pharmacol. 2009 Oct; 65(10):977-87. PMID: 19517101.
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    8. Sasi P, Abdulrahaman A, Mwai L, Muriithi S, Straimer J, Schieck E, Rippert A, Bashraheil M, Salim A, Peshu J, Awuondo K, Lowe B, Pirmohamed M, Winstanley P, Ward S, Nzila A, Borrmann S. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 01; 199(11):1575-82. PMID: 19405863.
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    9. O'Neill PM, Shone AE, Stanford D, Nixon G, Asadollahy E, Park BK, Maggs JL, Roberts P, Stocks PA, Biagini G, Bray PG, Davies J, Berry N, Hall C, Rimmer K, Winstanley PA, Hindley S, Bambal RB, Davis CB, Bates M, Gresham SL, Brigandi RA, Gomez-de-Las-Heras FM, Gargallo DV, Parapini S, Vivas L, Lander H, Taramelli D, Ward SA. Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine. J Med Chem. 2009 Apr 09; 52(7):1828-44. PMID: 19284751.
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    10. Alker AP, Juliano JJ, Meshnick SR, Owen A, Ochong E, Bell DJ, Johnson DJ, d'Alessandro U, Mulenga M, Muangnoicharoen S, Van Geertruyden JP, Winstanley PA, Bray PG, Ward SA. Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa. Antimicrob Agents Chemother. 2009 Apr; 53(4):1722; author reply 1722-3. PMID: 19299520; PMCID: PMC2663109.
    11. O'Neill PM, Park BK, Shone AE, Maggs JL, Roberts P, Stocks PA, Biagini GA, Bray PG, Gibbons P, Berry N, Winstanley PA, Mukhtar A, Bonar-Law R, Hindley S, Bambal RB, Davis CB, Bates M, Hart TK, Gresham SL, Lawrence RM, Brigandi RA, Gomez-delas-Heras FM, Gargallo DV, Ward SA. Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. J Med Chem. 2009 Mar 12; 52(5):1408-15. PMID: 19222165.
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    12. Winstanley P. Transactions of the Royal Society of Tropical Medicine and Hygiene. Research, education and capacity development in resource-poor settings--a festschrift for Professor M.E. Molyneux OBE. Preface. Trans R Soc Trop Med Hyg. 2009 Apr; 103 Suppl 1:S1. PMID: 19243804.
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    13. Ochong E, Bell DJ, Johnson DJ, D'Alessandro U, Mulenga M, Muangnoicharoen S, Van Geertruyden JP, Winstanley PA, Bray PG, Ward SA, Owen A. Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure. Antimicrob Agents Chemother. 2008 Nov; 52(11):3883-8. PMID: 18725445; PMCID: PMC2573156.
    14. Wootton DG, Opara H, Biagini GA, Kanjala MK, Duparc S, Kirby PL, Woessner M, Neate C, Nyirenda M, Blencowe H, Dube-Mbeye Q, Kanyok T, Ward S, Molyneux M, Dunyo S, Winstanley PA. Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria. PLoS One. 2008 Mar 05; 3(3):e1779. PMID: 18320064; PMCID: PMC2258152.
    15. Bell DJ, Nyirongo SK, Mukaka M, Zijlstra EE, Plowe CV, Molyneux ME, Ward SA, Winstanley PA. Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi. PLoS One. 2008 Feb 13; 3(2):e1578. PMID: 18270569; PMCID: PMC2229666.
    16. Pirmohamed M, Atuah KN, Dodoo AN, Winstanley P. Pharmacovigilance in developing countries. BMJ. 2007 Sep 08; 335(7618):462. PMID: 17823149; PMCID: PMC1971195.
    17. Amin AA, Walley T, Kokwaro GO, Winstanley PA, Snow RW. Reconciling national treatment policies and drug regulation in Kenya. Health Policy Plan. 2007 Mar; 22(2):111-2. PMID: 17227778; PMCID: PMC2653780.
    18. Bell DJ, Nyirongo SK, Molyneux ME, Winstanley PA, Ward SA. Practical HPLC methods for the quantitative determination of common antimalarials in Africa. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Mar 01; 847(2):231-6. PMID: 17098484.
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    19. Simpson JA, Hughes D, Manyando C, Bojang K, Aarons L, Winstanley P, Edwards G, Watkins WA, Ward S. Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone. Br J Clin Pharmacol. 2006 Mar; 61(3):289-300. PMID: 16487222; PMCID: PMC1885012.
    20. Winstanley P, Ward S. Malaria chemotherapy. Adv Parasitol. 2006; 61:47-76. PMID: 16735162.
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    21. Lang T, Hughes D, Kanyok T, Kengeya-Kayondo J, Marsh V, Haaland A, Pirmohamed M, Winstanley P. Beyond registration--measuring the public-health potential of new treatments for malaria in Africa. Lancet Infect Dis. 2006 Jan; 6(1):46-52. PMID: 16377534.
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    22. Khoo S, Back D, Winstanley P. The potential for interactions between antimalarial and antiretroviral drugs. AIDS. 2005 Jul 01; 19(10):995-1005. PMID: 15958830.
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    23. Nzila A, Ochong E, Nduati E, Gilbert K, Winstanley P, Ward S, Marsh K. Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet? Trans R Soc Trop Med Hyg. 2005 May; 99(5):341-6. PMID: 15780340.
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    24. Bell D, Winstanley P. Current issues in the treatment of uncomplicated malaria in Africa. Br Med Bull. 2004; 71:29-43. PMID: 15596867.
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    25. Clark RL, White TE, A Clode S, Gaunt I, Winstanley P, Ward SA. Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit. Birth Defects Res B Dev Reprod Toxicol. 2004 Dec; 71(6):380-94. PMID: 15617018.
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    26. Bates SJ, Winstanley PA, Watkins WM, Alloueche A, Bwika J, Happi TC, Kremsner PG, Kublin JG, Premji Z, Sibley CH. Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites. J Infect Dis. 2004 Nov 15; 190(10):1783-92. PMID: 15499534.
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    27. Amin AA, Hughes DA, Marsh V, Abuya TO, Kokwaro GO, Winstanley PA, Ochola SA, Snow RW. The difference between effectiveness and efficacy of antimalarial drugs in Kenya. Trop Med Int Health. 2004 Sep; 9(9):967-74. PMID: 15361109.
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    28. Winstanley P, Ward S, Snow R, Breckenridge A. Therapy of falciparum malaria in sub-saharan Africa: from molecule to policy. Clin Microbiol Rev. 2004 Jul; 17(3):612-37, table of contents. PMID: 15258096; PMCID: PMC452542.
    29. Alloueche A, Bailey W, Barton S, Bwika J, Chimpeni P, Falade CO, Fehintola FA, Horton J, Jaffar S, Kanyok T, Kremsner PG, Kublin JG, Lang T, Missinou MA, Mkandala C, Oduola AM, Premji Z, Robertson L, Sowunmi A, Ward SA, Winstanley PA. Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial. Lancet. 2004 Jun 05; 363(9424):1843-8. PMID: 15183620.
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    30. Nzila AM, Kokwaro G, Winstanley PA, Marsh K, Ward SA. Therapeutic potential of folate uptake inhibition in Plasmodium falciparum. Trends Parasitol. 2004 Mar; 20(3):109-12. PMID: 16676416.
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    31. O'Neill PM, Mukhtar A, Stocks PA, Randle LE, Hindley S, Ward SA, Storr RC, Bickley JF, O'Neil IA, Maggs JL, Hughes RH, Winstanley PA, Bray PG, Park BK. Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials. J Med Chem. 2003 Nov 06; 46(23):4933-45. PMID: 14584944.
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    32. Nzila A, Mberu E, Bray P, Kokwaro G, Winstanley P, Marsh K, Ward S. Chemosensitization of Plasmodium falciparum by probenecid in vitro. Antimicrob Agents Chemother. 2003 Jul; 47(7):2108-12. PMID: 12821454; PMCID: PMC161864.
    33. Winstanley P. The contribution of clinical pharmacology to antimalarial drug discovery and development. Br J Clin Pharmacol. 2003 05; 55(5):464-8. PMID: 12755808; PMCID: PMC1884199.
    34. Lochhead J, Movaffaghy A, Falsini B, Winstanley PA, Mberu EK, Riva CE, Molyneux ME, Taylor TE, Harding SP. The effect of quinine on the electroretinograms of children with pediatric cerebral malaria. J Infect Dis. 2003 Apr 15; 187(8):1342-5. PMID: 12696018.
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    35. Winstanley P. Coping with malaria in the face of resistance. Int J Infect Dis. 2002 Dec; 6(4):246-52. PMID: 12718816.
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    36. Sulo J, Chimpeni P, Hatcher J, Kublin JG, Plowe CV, Molyneux ME, Marsh K, Taylor TE, Watkins WM, Winstanley PA. Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial. Lancet. 2002 Oct 12; 360(9340):1136-43. PMID: 12387962.
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    37. Winstanley PA, Ward SA, Snow RW. Clinical status and implications of antimalarial drug resistance. Microbes Infect. 2002 Feb; 4(2):157-64. PMID: 11880047.
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    38. Kublin JG, Dzinjalamala FK, Kamwendo DD, Malkin EM, Cortese JF, Martino LM, Mukadam RA, Rogerson SJ, Lescano AG, Molyneux ME, Winstanley PA, Chimpeni P, Taylor TE, Plowe CV. Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria. J Infect Dis. 2002 Feb 01; 185(3):380-8. PMID: 11807721.
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    39. Sibley CH, Hyde JE, Sims PF, Plowe CV, Kublin JG, Mberu EK, Cowman AF, Winstanley PA, Watkins WM, Nzila AM. Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next? Trends Parasitol. 2001 Dec; 17(12):582-8. PMID: 11756042.
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    40. Winstanley P. Modern chemotherapeutic options for malaria. Lancet Infect Dis. 2001 Nov; 1(4):242-50. PMID: 11871511.
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    41. Winstanley P. Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria. Trop Med Int Health. 2001 Nov; 6(11):952-4. PMID: 11703851.
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    42. Mutabingwa T, Nzila A, Mberu E, Nduati E, Winstanley P, Hills E, Watkins W. Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania. Lancet. 2001 Oct 13; 358(9289):1218-23. PMID: 11675058.
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    43. Beeson JG, Winstanley PA, McFadden GI, Brown GV. New agents to combat malaria. Nat Med. 2001 Feb; 7(2):149-50. PMID: 11175835.
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    44. Nzila AM, Nduati E, Mberu EK, Hopkins Sibley C, Monks SA, Winstanley PA, Watkins WM. Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum. J Infect Dis. 2000 Jun; 181(6):2023-8. PMID: 10837185.
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    45. Almond DS, Szwandt IS, Edwards G, Lee MG, Winstanley PA. Disposition of intravenous pyrimethamine in healthy volunteers. Antimicrob Agents Chemother. 2000 Jun; 44(6):1691-3. PMID: 10817730; PMCID: PMC89934.
    46. Winstanley PA. Chemotherapy for falciparum malaria: the armoury, the problems and the prospects. Parasitol Today. 2000 Apr; 16(4):146-53. PMID: 10725901.
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    47. Nzila AM, Mberu EK, Sulo J, Dayo H, Winstanley PA, Sibley CH, Watkins WM. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. Antimicrob Agents Chemother. 2000 Apr; 44(4):991-6. PMID: 10722502; PMCID: PMC89803.
    48. Crawley J, Waruiru C, Mithwani S, Mwangi I, Watkins W, Ouma D, Winstanley P, Peto T, Marsh K. Effect of phenobarbital on seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study. Lancet. 2000 Feb 26; 355(9205):701-6. PMID: 10703801.
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    49. Maggs JL, Bishop LP, Edwards G, O'Neill PM, Ward SA, Winstanley PA, Park BK. Biliary metabolites of beta-artemether in rats: biotransformations of an antimalarial endoperoxide. Drug Metab Dispos. 2000 Feb; 28(2):209-17. PMID: 10640520.
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    50. Kinyanjui SM, Mberu EK, Winstanley PA, Jacobus DP, Watkins WM. The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug. Am J Trop Med Hyg. 1999 Jun; 60(6):943-7. PMID: 10403325.
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    51. Pähkla R, Lambert J, Ansko P, Winstanley P, Davies PD, Kiivet RA. Comparative bioavailability of three different preparations of rifampicin. J Clin Pharm Ther. 1999 Jun; 24(3):219-25. PMID: 10438182.
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    52. Watkins WM, Mberu EK, Winstanley PA, Plowe CV. More on 'the efficacy of antifolate antimalarial combinations in Africa'. Parasitol Today. 1999 Apr; 15(4):131-2. PMID: 10322331.
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    53. Winstanley P. Albendazole for mass treatment of asymptomatic trichuris infections. Lancet. 1998 Oct 03; 352(9134):1080-1. PMID: 9798577.
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    54. Winstanley P. Malaria: treatment. J R Coll Physicians Lond. 1998 May-Jun; 32(3):203-7. PMID: 9670144.
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    55. Haruki K, Winstanley PA, Watkins WM, Marsh K. Quinine sensitivity of isolates of Plasmodium falciparum from the coast of Kenya. Trans R Soc Trop Med Hyg. 1998 Mar-Apr; 92(2):195-6. PMID: 9764332.
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    56. Winstanley P, Olliaro P. Clinical trials of chemotherapy for falciparum malaria. Expert Opin Investig Drugs. 1998 Feb; 7(2):261-71. PMID: 15991958.
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    57. Nzila-Mounda A, Mberu EK, Sibley CH, Plowe CV, Winstanley PA, Watkins WM. Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain. Antimicrob Agents Chemother. 1998 Jan; 42(1):164-9. PMID: 9449279; PMCID: PMC105474.
    58. Plowe CV, Cortese JF, Djimde A, Nwanyanwu OC, Watkins WM, Winstanley PA, Estrada-Franco JG, Mollinedo RE, Avila JC, Cespedes JL, Carter D, Doumbo OK. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. J Infect Dis. 1997 Dec; 176(6):1590-6. PMID: 9395372.
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    59. Watkins WM, Mberu EK, Winstanley PA, Plowe CV. The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses. Parasitol Today. 1997 Dec; 13(12):459-64. PMID: 15275132.
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    60. Breckenridge AM, Winstanley PA. Clinical pharmacology and malaria. Ann Trop Med Parasitol. 1997 Oct; 91(7):727-33. PMID: 9625927.
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    61. Amukoye E, Winstanley PA, Watkins WM, Snow RW, Hatcher J, Mosobo M, Ngumbao E, Lowe B, Ton M, Minyiri G, Marsh K. Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria. Antimicrob Agents Chemother. 1997 Oct; 41(10):2261-4. PMID: 9333058; PMCID: PMC164103.
    62. Hero M, Harding SP, Riva CE, Winstanley PA, Peshu N, Marsh K. Photographic and angiographic characterization of the retina of Kenyan children with severe malaria. Arch Ophthalmol. 1997 Aug; 115(8):997-1003. PMID: 9258221.
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    63. Pirmohamed M, Winstanley P. Hepatitis B vaccine and neurotoxicity. Postgrad Med J. 1997 Jul; 73(861):462-3. PMID: 9338045; PMCID: PMC2431400.
    64. Winstanley P, Watkins W, Muhia D, Szwandt S, Amukoye E, Marsh K. Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range. Trans R Soc Trop Med Hyg. 1997 May-Jun; 91(3):322-7. PMID: 9231209.
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    65. Murphy SA, Mberu E, Muhia D, English M, Crawley J, Waruiru C, Lowe B, Newton CR, Winstanley P, Marsh K, Watkins WM. The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study. Trans R Soc Trop Med Hyg. 1997 May-Jun; 91(3):331-4. PMID: 9231211.
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    66. Winstanley P. New prospects for the treatment of malaria. Expert Opin Investig Drugs. 1997 Apr; 6(4):447-51. PMID: 15989612.
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    67. Newton CR, Chokwe T, Schellenberg JA, Winstanley PA, Forster D, Peshu N, Kirkham FJ, Marsh K. Coma scales for children with severe falciparum malaria. Trans R Soc Trop Med Hyg. 1997 Mar-Apr; 91(2):161-5. PMID: 9196757.
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    68. Newton CR, Crawley J, Sowumni A, Waruiru C, Mwangi I, English M, Murphy S, Winstanley PA, Marsh K, Kirkham FJ. Intracranial hypertension in Africans with cerebral malaria. Arch Dis Child. 1997 Mar; 76(3):219-26. PMID: 9135262; PMCID: PMC1717090.
    69. Newton CR, Warn PA, Winstanley PA, Peshu N, Snow RW, Pasvol G, Marsh K. Severe anaemia in children living in a malaria endemic area of Kenya. Trop Med Int Health. 1997 Feb; 2(2):165-78. PMID: 9472302.
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    70. Kokwaro G, Edwards G, Roberts P, Ward S, Winstanley P, Watkins W. Infection with Plasmodium berghei alters benzodiazepine receptor in rat brain. Arch Med Res. 1997; 28(3):425-7. PMID: 9291643.
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    71. Winstanley P. Mefloquine: the benefits outweigh the risks. Br J Clin Pharmacol. 1996 Oct; 42(4):411-3. PMID: 8904611; PMCID: PMC2042699.
    72. Murphy S, English M, Waruiru C, Mwangi I, Amukoye E, Crawley J, Newton C, Winstanley P, Peshu N, Marsh K. An open randomized trial of artemether versus quinine in the treatment of cerebral malaria in African children. Trans R Soc Trop Med Hyg. 1996 May-Jun; 90(3):298-301. PMID: 8758084.
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    73. Bonington A, Davidson RN, Winstanley PA, Pasvol G. Fatal quinine cardiotoxicity in the treatment of falciparum malaria. Trans R Soc Trop Med Hyg. 1996 May-Jun; 90(3):305-7. PMID: 8758086.
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    74. Waruiru CM, Newton CR, Forster D, New L, Winstanley P, Mwangi I, Marsh V, Winstanley M, Snow RW, Marsh K. Epileptic seizures and malaria in Kenyan children. Trans R Soc Trop Med Hyg. 1996 Mar-Apr; 90(2):152-5. PMID: 8761576.
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    75. Watkins WM, Mungai M, Muhia DK, Mberu EK, Gathua S, Winstanley PA, Gilks CF, Nunn P. Cutaneous hypersensitivity reactions to thiacetazone, HIV infection and thiacetazone concentrations in plasma. Br J Clin Pharmacol. 1996 Feb; 41(2):160-2. PMID: 8838444.
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    76. Winstanley P. Pyronaridine: a promising drug for Africa? Lancet. 1996 Jan 06; 347(8993):2-3. PMID: 8531544.
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    77. Murphy S, Watkins WM, Bray PG, Lowe B, Winstanley PA, Peshu N, Marsh K. Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine. Am J Trop Med Hyg. 1995 Sep; 53(3):303-5. PMID: 7573718.
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    78. Winstanley P, Khoo S, Szwandt S, Edwards G, Wilkins E, Tija J, Coker R, McKane W, Beeching N, Watkin S, et al. Marked variation in pyrimethamine disposition in AIDS patients treated for cerebral toxoplasmosis. J Antimicrob Chemother. 1995 Aug; 36(2):435-9. PMID: 8522475.
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    79. Murphy S, English M, Omar A, Crawley J, Waruiru C, Mwangi I, Amukoye E, Peshu N, Newton CR, Winstanley PA, et al. The management of severe malaria in children: a review. East Afr Med J. 1995 Aug; 72(8):536-9. PMID: 7588152.
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    80. Winstanley P. Drug treatment of toxoplasmic encephalitis in acquired immunodeficiency syndrome. Postgrad Med J. 1995 Jul; 71(837):404-8. PMID: 7567731; PMCID: PMC2397974.
    81. Marsh K, Forster D, Waruiru C, Mwangi I, Winstanley M, Marsh V, Newton C, Winstanley P, Warn P, Peshu N, et al. Indicators of life-threatening malaria in African children. N Engl J Med. 1995 May 25; 332(21):1399-404. PMID: 7723795.
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    82. Winstanley PA, Mberu EK, Szwandt IS, Breckenridge AM, Watkins WM. In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs. Antimicrob Agents Chemother. 1995 Apr; 39(4):948-52. PMID: 7786001; PMCID: PMC162659.
    83. Watkins WM, Winstanley PA, Mberu EK, Kokwaro G, Murphy SA, Newton CJ, Mwangi I, Forster D, Marsh K. Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria. Br J Clin Pharmacol. 1995 Mar; 39(3):283-7. PMID: 7619670; PMCID: PMC1365005.
    84. Grange JM, Winstanley PA, Davies PD. Clinically significant drug interactions with antituberculosis agents. Drug Saf. 1994 Oct; 11(4):242-51. PMID: 7848544.
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    85. Winstanley PA, Mberu EK, Watkins WM, Murphy SA, Lowe B, Marsh K. Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen. Trans R Soc Trop Med Hyg. 1994 Sep-Oct; 88(5):577-80. PMID: 7992345.
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    86. Edwards G, Winstanley PA, Ward SA. Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations. Clin Pharmacokinet. 1994 Aug; 27(2):150-65. PMID: 7955777.
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    87. Nunn P, Porter J, Winstanley P. Thiacetazone--avoid like poison or use with care? Trans R Soc Trop Med Hyg. 1993 Sep-Oct; 87(5):578-82. PMID: 7505496.
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    88. Snow RW, Schellenberg JR, Peshu N, Forster D, Newton CR, Winstanley PA, Mwangi I, Waruiru C, Warn PA, Newbold C, et al. Periodicity and space-time clustering of severe childhood malaria on the coast of Kenya. Trans R Soc Trop Med Hyg. 1993 Jul-Aug; 87(4):386-90. PMID: 8249058.
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    89. Newton CR, Winstanley PA, Watkins WM, Mwangi IN, Waruiru CM, Mberu EK, Warn PA, Nevill CG, Marsh K. A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy. Trans R Soc Trop Med Hyg. 1993 Mar-Apr; 87(2):207-10. PMID: 8337731.
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    90. Winstanley P, Newton C, Watkins W, Mberu E, Ward S, Warn P, Mwangi I, Waruiru C, Pasvol G, Warrell D, et al. Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration. Trans R Soc Trop Med Hyg. 1993 Mar-Apr; 87(2):201-6. PMID: 8337730.
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    91. Winstanley PA. Treatment and prevention of falciparum malaria in Africa. J R Coll Physicians Lond. 1992 Oct; 26(4):445-9. PMID: 1359133.
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    92. Snow RW, Armstrong JR, Forster D, Winstanley MT, Marsh VM, Newton CR, Waruiru C, Mwangi I, Winstanley PA, Marsh K. Childhood deaths in Africa: uses and limitations of verbal autopsies. Lancet. 1992 Aug 08; 340(8815):351-5. PMID: 1353814.
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    93. Winstanley PA, Watkins WM. Pharmacology and parasitology: integrating experimental methods and approaches to falciparum malaria. Br J Clin Pharmacol. 1992 Jun; 33(6):575-81. PMID: 1389929; PMCID: PMC1381348.
    94. Winstanley PA, Watkins WM, Newton CR, Nevill C, Mberu E, Warn PA, Waruiru CM, Mwangi IN, Warrell DA, Marsh K. The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria. Br J Clin Pharmacol. 1992 Feb; 33(2):143-8. PMID: 1550695; PMCID: PMC1381299.
    95. Winstanley PA, Newton CR, Pasvol G, Kirkham FJ, Mberu E, Peshu N, Ward SA, Were JB, Warrell DA, Marsh K. Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects. Br J Clin Pharmacol. 1992 Feb; 33(2):149-54. PMID: 1550696; PMCID: PMC1381300.
    96. Pasvol G, Newton CR, Winstanley PA, Watkins WM, Peshu NM, Were JB, Marsh K, Warrell DA. Quinine treatment of severe falciparum malaria in African children: a randomized comparison of three regimens. Am J Trop Med Hyg. 1991 Dec; 45(6):702-13. PMID: 1763797.
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    97. Mberu EK, Ward SA, Winstanley PA, Watkins WM. Measurement of quinine in filter paper-absorbed blood by high-performance liquid chromatography. J Chromatogr. 1991 Sep 18; 570(1):180-4. PMID: 1797824.
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    98. Newton CR, Winstanley PA, Marsh K. Retinal haemorrhages in falciparum malaria. Arch Dis Child. 1991 Jun; 66(6):753. PMID: 2053813; PMCID: PMC1793163.
    99. Newton CR, Kirkham FJ, Winstanley PA, Pasvol G, Peshu N, Warrell DA, Marsh K. Intracranial pressure in African children with cerebral malaria. Lancet. 1991 Mar 09; 337(8741):573-6. PMID: 1671941.
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    100. Hosking G, Miles R, Winstanley P. Seizures in patients with cerebral palsy. Dev Med Child Neurol. 1990 Nov; 32(11):1026-7. PMID: 2269399.
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    101. Winstanley PA, Simooya O, Kofi-Ekue JM, Walker O, Salako LA, Edwards G, Orme ML, Breckenridge AM. The disposition of amodiaquine in Zambians and Nigerians with malaria. Br J Clin Pharmacol. 1990 Jun; 29(6):695-701. PMID: 2378788; PMCID: PMC1380171.
    102. Winstanley PA, Coleman JW, Maggs JL, Breckenridge AM, Park BK. The toxicity of amodiaquine and its principal metabolites towards mononuclear leucocytes and granulocyte/monocyte colony forming units. Br J Clin Pharmacol. 1990 Apr; 29(4):479-85. PMID: 2328196; PMCID: PMC1380119.
    103. Newton CR, Pasvol G, Winstanley PA, Warrell DA. Cerebral malaria: what is unarousable coma? Lancet. 1990 Feb 24; 335(8687):472. PMID: 1968190.
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    104. Walley T, Winstanley P, Roberts D, Grimmer M, Orme M, Breckenridge A. Adverse effects of captopril in hospital outpatients with hypertension. Postgrad Med J. 1990 Feb; 66(772):106-9. PMID: 2190201; PMCID: PMC2429545.
    105. Winstanley PA, Orme ML. The effects of food on drug bioavailability. Br J Clin Pharmacol. 1989 Dec; 28(6):621-8. PMID: 2692684; PMCID: PMC1380032.
    106. Winstanley PA, Irvin LE, Smith JC, Orme ML, Breckenridge AM. Adverse drug reactions: a hospital pharmacy-based reporting scheme. Br J Clin Pharmacol. 1989 Jul; 28(1):113-6. PMID: 2775609; PMCID: PMC1379978.
    107. Winstanley PA, Edwards G, Curtis CG, Orme ML, Powell GM, Breckenridge AM. Tissue distribution and excretion of amodiaquine in the rat. J Pharm Pharmacol. 1988 May; 40(5):343-9. PMID: 2899630.
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    108. Winstanley PA, Back DJ, Breckenridge AM. Inhibition of theophylline metabolism by interferon. Lancet. 1987 Dec 05; 2(8571):1340. PMID: 2446094.
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    109. Winstanley PA, Breckenridge AM. Currently important antimalarial drugs. Ann Trop Med Parasitol. 1987 Oct; 81(5):619-27. PMID: 3331251.
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    110. Roberts DH, Tsao Y, Grimmer SF, Winstanley PA, Orme ML, Breckenridge AM. Haemodynamic effects of atenolol, labetalol, pindolol and captopril: a comparison in hypertensive patients with special reference to changes in limb blood flow, heart rate and left ventricular function. Br J Clin Pharmacol. 1987 Aug; 24(2):163-72. PMID: 2887190; PMCID: PMC1387745.
    111. Winstanley PA. The prophylaxis and treatment of malaria. Blood Rev. 1987 Mar; 1(1):44-9. PMID: 3332086.
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    112. Winstanley P, Edwards G, Orme M, Breckenridge A. The disposition of amodiaquine in man after oral administration. Br J Clin Pharmacol. 1987 Jan; 23(1):1-7. PMID: 3814460; PMCID: PMC1386133.
    113. Winstanley PA, Edwards G, Orme ML, Breckenridge AM. Effect of dose size on amodiaquine pharmacokinetics after oral administration. Eur J Clin Pharmacol. 1987; 33(3):331-3. PMID: 3691624.
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    114. Winstanley PA, Manning AP, Lintott DJ, Axon AT. Endoscopic retrograde cholangio-pancreatography in pancreatitis with persistent or recurrent pain. Int J Pancreatol. 1986 Dec; 1(5-6):407-12. PMID: 3681032.
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    115. Juby LD, Axon AT, Wright V, Winstanley P, Rothwell J. Intestinal permeability and inflammation in rheumatoid arthritis. Br J Rheumatol. 1986 May; 25(2):226-7. PMID: 3708242.
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    116. Winstanley PA, Edwards G, Orme ML, Breckenridge AM. The detection of amodiaquine in blood after oral administration. Br J Clin Pharmacol. 1986 May; 21(5):552. PMID: 3718814; PMCID: PMC1401019.
    117. Hatton CS, Peto TE, Bunch C, Pasvol G, Russell SJ, Singer CR, Edwards G, Winstanley P. Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. Lancet. 1986 Feb 22; 1(8478):411-4. PMID: 2868340.
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    118. Hosking G, Hosking J, Winstanley P, Green A, Grimsley M. A biochemical study on mothers of children with congenital neurodevelopmental abnormalities. Biochem Med. 1985 Dec; 34(3):287-96. PMID: 4096717.
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    119. Winstanley PA, Tjia J, Back DJ, Hobson D, Breckenridge AM. Lack of effect of highly purified subunit influenza vaccination on theophylline metabolism. Br J Clin Pharmacol. 1985 Jul; 20(1):47-53. PMID: 4027135; PMCID: PMC1400622.
    120. Winstanley PA, Ellis WR, Hamilton I, Lintott DJ, Axon AT. Medium term complications of endoscopic biliary sphincterotomy. Gut. 1985 Jul; 26(7):730-3. PMID: 4018638; PMCID: PMC1432994.
    121. Winstanley PA, Young JB, Axon AT, Brownjohn AM, Cooper EH. Renal proximal tubular dysfunction in Crohn's disease. Br Med J (Clin Res Ed). 1984 May 26; 288(6430):1612-3. PMID: 6426662; PMCID: PMC1441253.
    122. WINSTANLEY P. [The future organization of pathology in Great Britain]. Dtsch Med Wochenschr. 1962 May 11; 87:1016-7. PMID: 14007570.
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