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Professor Jonathan Kweku Stiles

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dickinson-Copeland CM, Wilson NO, Liu M, Driss A, Salifu H, Adjei AA, Wilson M, Gyan B, Oduro D, Badu K, Botchway F, Anderson W, Bond V, Bacanamwo M, Singh S, Stiles JK. Heme-Mediated Induction of CXCL10 and Depletion of CD34+ Progenitor Cells Is Toll-Like Receptor 4 Dependent. PLoS One. 2015; 10(11):e0142328. PMID: 26555697.
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    2. Capers PL, Hyacinth HI, Cue S, Chappa P, Vikulina T, Roser-Page S, Weitzmann MN, Archer DR, Newman GW, Quarshie A, Stiles JK, Hibbert JM. Body composition and grip strength are improved in transgenic sickle mice fed a high-protein diet. J Nutr Sci. 2015; 4:e6. PMID: 26090102.
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    3. Thompson WE, Pattillo RA, Stiles JK, Schatten G. Biomedical research's unpaid debt: NIH's initiative to support and implement fairer competition for minority students is a welcome step to redress the exploitation of African Americans by science. EMBO Rep. 2014 Apr; 15(4):333-7. PMID: 24652854.
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    4. Solomon W, Wilson NO, Anderson L, Pitts S, Patrickson J, Liu M, Ford BD, Stiles JK. Neuregulin-1 attenuates mortality associated with experimental cerebral malaria. J Neuroinflammation. 2014 Jan 17; 11:9. PMID: 24433482.
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    5. Wilson N, Driss A, Solomon W, Dickinson-Copeland C, Salifu H, Jain V, Singh N, Stiles J. CXCL10 gene promoter polymorphism -1447A>G correlates with plasma CXCL10 levels and is associated with male susceptibility to cerebral malaria. PLoS One. 2013; 8(12):e81329. PMID: 24349056.
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    6. Liu M, Wilson NO, Hibbert JM, Stiles JK. STAT3 regulates MMP3 in heme-induced endothelial cell apoptosis. PLoS One. 2013; 8(8):e71366. PMID: 23967200.
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    7. Wilson NO, Solomon W, Anderson L, Patrickson J, Pitts S, Bond V, Liu M, Stiles JK. Pharmacologic inhibition of CXCL10 in combination with anti-malarial therapy eliminates mortality associated with murine model of cerebral malaria. PLoS One. 2013; 8(4):e60898. PMID: 23630573.
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    8. Hyacinth HI, Gee BE, Adamkiewicz TV, Adams RJ, Kutlar A, Stiles JK, Hibbert JM. Plasma BDNF and PDGF-AA levels are associated with high TCD velocity and stroke in children with sickle cell anemia. Cytokine. 2012 Oct; 60(1):302-8. PMID: 22704695.
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    9. Wilson NO, Ceesay FK, Hibbert JM, Driss A, Obed SA, Adjei AA, Gyasi RK, Anderson WA, Stiles JK. Pregnancy outcomes among patients with sickle cell disease at Korle-Bu Teaching Hospital, Accra, Ghana: retrospective cohort study. Am J Trop Med Hyg. 2012 Jun; 86(6):936-42. PMID: 22665597.
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    10. Liu M, Amodu AS, Pitts S, Patrickson J, Hibbert JM, Battle M, Ofori-Acquah SF, Stiles JK. Heme mediated STAT3 activation in severe malaria. PLoS One. 2012; 7(3):e34280. PMID: 22479586.
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    11. Driss A, Wilson NO, Mason K, Hyacinth HI, Hibbert JM, Serjeant GR, Stiles JK. Elevated IL-1a and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestration. Dis Markers. 2012; 32(5):295-300. PMID: 22674409.
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    12. Jain V, Lucchi NW, Wilson NO, Blackstock AJ, Nagpal AC, Joel PK, Singh MP, Udhayakumar V, Stiles JK, Singh N. Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India. Malar J. 2011 Dec 23; 10:383. PMID: 22192385.
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    13. Driss A, Hibbert JM, Wilson NO, Iqbal SA, Adamkiewicz TV, Stiles JK. Genetic polymorphisms linked to susceptibility to malaria. Malar J. 2011 Sep 19; 10:271. PMID: 21929748.
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    14. Liu M, Guo S, Hibbert JM, Jain V, Singh N, Wilson NO, Stiles JK. CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications. Cytokine Growth Factor Rev. 2011 Jun; 22(3):121-30. PMID: 21802343.
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    15. Jolly PE, Shuaib FM, Jiang Y, Preko P, Baidoo J, Stiles JK, Wang JS, Phillips TD, Williams JH. Association of high viral load and abnormal liver function with high aflatoxin B1-albumin adduct levels in HIV-positive Ghanaians: preliminary observations. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Sep; 28(9):1224-34. PMID: 21749228.
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    16. Wilson NO, Ceesay FK, Obed SA, Adjei AA, Gyasi RK, Rodney P, Ndjakani Y, Anderson WA, Lucchi NW, Stiles JK. Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant women. Am J Trop Med Hyg. 2011 Jul; 85(1):12-21. PMID: 21734118.
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    17. Sarfo BY, Wilson NO, Bond VC, Stiles JK. Plasmodium berghei ANKA infection increases Foxp3, IL-10 and IL-2 in CXCL-10 deficient C57BL/6 mice. Malar J. 2011 Mar 28; 10:69. PMID: 21439091.
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    18. Lucchi NW, Jain V, Wilson NO, Singh N, Udhayakumar V, Stiles JK. Potential serological biomarkers of cerebral malaria. Dis Markers. 2011; 31(6):327-35. PMID: 22182805.
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    19. Wilson NO, Jain V, Roberts CE, Lucchi N, Joel PK, Singh MP, Nagpal AC, Dash AP, Udhayakumar V, Singh N, Stiles JK. CXCL4 and CXCL10 predict risk of fatal cerebral malaria. Dis Markers. 2011; 30(1):39-49. PMID: 21508508.
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    20. Shuaib FM, Jolly PE, Ehiri JE, Jiang Y, Ellis WO, Stiles JK, Yatich NJ, Funkhouser E, Person SD, Wilson C, Williams JH. Association between anemia and aflatoxin B1 biomarker levels among pregnant women in Kumasi, Ghana. Am J Trop Med Hyg. 2010 Nov; 83(5):1077-83. PMID: 21036841.
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    21. Wilson NO, Bythwood T, Solomon W, Jolly P, Yatich N, Jiang Y, Shuaib F, Adjei AA, Anderson W, Stiles JK. Elevated levels of IL-10 and G-CSF associated with asymptomatic malaria in pregnant women. Infect Dis Obstet Gynecol. 2010; 2010. PMID: 20706538.
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    22. Yatich NJ, Funkhouser E, Ehiri JE, Agbenyega T, Stiles JK, Rayner JC, Turpin A, Ellis WO, Jiang Y, Williams JH, Afriyie-Gwayu E, Phillips T, Jolly PE. Malaria, intestinal helminths and other risk factors for stillbirth in Ghana. Infect Dis Obstet Gynecol. 2010; 2010:350763. PMID: 20379355.
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    23. Yatich NJ, Jolly PE, Funkhouser E, Agbenyega T, Rayner JC, Ehiri JE, Turpin A, Stiles JK, Ellis WO, Jiang Y, Williams JH. The effect of malaria and intestinal helminth coinfection on birth outcomes in Kumasi, Ghana. Am J Trop Med Hyg. 2010 Jan; 82(1):28-34. PMID: 20064991.
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    24. Mixson-Hayden T, Jain V, McCollum AM, Poe A, Nagpal AC, Dash AP, Stiles JK, Udhayakumar V, Singh N. Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in India. Antimicrob Agents Chemother. 2010 Mar; 54(3):997-1006. PMID: 20038626.
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    25. Asare K, Gee BE, Stiles JK, Wilson NO, Driss A, Quarshie A, Adams RJ, Kutlar A, Hibbert JM. Plasma interleukin-1beta concentration is associated with stroke in sickle cell disease. Cytokine. 2010 Jan; 49(1):39-44. PMID: 19900820.
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    26. Ramey K, Eko FO, Thompson WE, Armah H, Igietseme JU, Stiles JK. Immunolocalization and challenge studies using a recombinant Vibrio cholerae ghost expressing Trypanosoma brucei Ca(2+) ATPase (TBCA2) antigen. Am J Trop Med Hyg. 2009 Sep; 81(3):407-15. PMID: 19706905.
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    27. Yatich NJ, Yi J, Agbenyega T, Turpin A, Rayner JC, Stiles JK, Ellis WO, Funkhouser E, Ehiri JE, Williams JH, Jolly PE. Malaria and intestinal helminth co-infection among pregnant women in Ghana: prevalence and risk factors. Am J Trop Med Hyg. 2009 Jun; 80(6):896-901. PMID: 19478245.
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    28. Jain V, McClintock S, Nagpal AC, Dash AP, Stiles JK, Udhayakumar V, Singh N, Lucchi NW. Macrophage migration inhibitory factor is associated with mortality in cerebral malaria patients in India. BMC Res Notes. 2009 Mar 06; 2:36. PMID: 19284533.
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    29. Meade JC, de Mestral J, Stiles JK, Secor WE, Finley RW, Cleary JD, Lushbaugh WB. Genetic diversity of Trichomonas vaginalis clinical isolates determined by EcoRI restriction fragment length polymorphism of heat-shock protein 70 genes. Am J Trop Med Hyg. 2009 Feb; 80(2):245-51. PMID: 19190222.
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    30. Aviles H, Stiles J, O'Donnell P, Orshal J, Leid J, Sonnenfeld G, Monroy F. Kinetics of systemic cytokine and brain chemokine gene expression in murine toxoplasma infection. J Parasitol. 2008 Dec; 94(6):1282-8. PMID: 19127964.
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    31. Jain V, Nagpal AC, Joel PK, Shukla M, Singh MP, Gupta RB, Dash AP, Mishra SK, Udhayakumar V, Stiles JK, Singh N. Burden of cerebral malaria in central India (2004-2007). Am J Trop Med Hyg. 2008 Oct; 79(4):636-42. PMID: 18840756.
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    32. Wilson NO, Huang MB, Anderson W, Bond V, Powell M, Thompson WE, Armah HB, Adjei AA, Gyasi R, Tettey Y, Stiles JK. Soluble factors from Plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells. Mol Biochem Parasitol. 2008 Dec; 162(2):172-6. PMID: 18848585.
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    33. Lucchi NW, Tongren JE, Jain V, Nagpal AC, Kauth CW, Woehlbier U, Bujard H, Dash AP, Singh N, Stiles JK, Udhayakumar V. Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India. Malar J. 2008 Jul 04; 7:121. PMID: 18601721.
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    34. Archer DR, Stiles JK, Newman GW, Quarshie A, Hsu LL, Sayavongsa P, Perry J, Jackson EM, Hibbert JM. C-reactive protein and interleukin-6 are decreased in transgenic sickle cell mice fed a high protein diet. J Nutr. 2008 Jun; 138(6):1148-52. PMID: 18492848.
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    35. Jain V, Armah HB, Tongren JE, Ned RM, Wilson NO, Crawford S, Joel PK, Singh MP, Nagpal AC, Dash AP, Udhayakumar V, Singh N, Stiles JK. Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J. 2008 May 19; 7:83. PMID: 18489763.
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    36. Wilson NO, Adjei AA, Anderson W, Baidoo S, Stiles JK. Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients. Am J Trop Med Hyg. 2008 May; 78(5):733-5. PMID: 18458305.
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    37. Gregory-Bass RC, Olatinwo M, Xu W, Matthews R, Stiles JK, Thomas K, Liu D, Tsang B, Thompson WE. Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis. Int J Cancer. 2008 May 01; 122(9):1923-30. PMID: 18183577.
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    38. Armah HB, Wilson NO, Sarfo BY, Powell MD, Bond VC, Anderson W, Adjei AA, Gyasi RK, Tettey Y, Wiredu EK, Tongren JE, Udhayakumar V, Stiles JK. Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J. 2007 Nov 12; 6:147. PMID: 17997848.
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    39. Chowdhury I, Xu W, Stiles JK, Zeleznik A, Yao X, Matthews R, Thomas K, Thompson WE. Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin. Endocrinology. 2007 Jan; 148(1):206-17. PMID: 17038561.
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    40. Palaniappan R, Singh S, Singh UP, Singh R, Ades EW, Briles DE, Hollingshead SK, Royal W, Sampson JS, Stiles JK, Taub DD, Lillard JW. CCL5 modulates pneumococcal immunity and carriage. J Immunol. 2006 Feb 15; 176(4):2346-56. PMID: 16455992.
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    41. Sarfo BY, Armah HB, Irune I, Adjei AA, Olver CS, Singh S, Lillard JW, Stiles JK. Plasmodium yoelii 17XL infection up-regulates RANTES, CCR1, CCR3 and CCR5 expression, and induces ultrastructural changes in the cerebellum. Malar J. 2005 Dec 16; 4:63. PMID: 16359553.
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    42. Armah H, Dodoo AK, Wiredu EK, Stiles JK, Adjei AA, Gyasi RK, Tettey Y. High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria. Ann Trop Med Parasitol. 2005 Oct; 99(7):629-47. PMID: 16212798.
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    43. He Q, Moore TT, Eko FO, Lyn D, Ananaba GA, Martin A, Singh S, James L, Stiles J, Black CM, Igietseme JU. Molecular basis for the potency of IL-10-deficient dendritic cells as a highly efficient APC system for activating Th1 response. J Immunol. 2005 Apr 15; 174(8):4860-9. PMID: 15814713.
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    44. Hibbert JM, Hsu LL, Bhathena SJ, Irune I, Sarfo B, Creary MS, Gee BE, Mohamed AI, Buchanan ID, Al-Mahmoud A, Stiles JK. Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease. Exp Biol Med (Maywood). 2005 Jan; 230(1):68-74. PMID: 15618128.
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    45. Singh S, Singh UP, Stiles JK, Grizzle WE, Lillard JW. Expression and functional role of CCR9 in prostate cancer cell migration and invasion. Clin Cancer Res. 2004 Dec 15; 10(24):8743-50. PMID: 15623660.
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    46. Williams JH, Phillips TD, Jolly PE, Stiles JK, Jolly CM, Aggarwal D. Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. Am J Clin Nutr. 2004 Nov; 80(5):1106-22. PMID: 15531656.
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    47. Sarfo BY, Singh S, Lillard JW, Quarshie A, Gyasi RK, Armah H, Adjei AA, Jolly P, Stiles JK. The cerebral-malaria-associated expression of RANTES, CCR3 and CCR5 in post-mortem tissue samples. Ann Trop Med Parasitol. 2004 Apr; 98(3):297-303. PMID: 15119976.
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    48. Thompson WE, Asselin E, Branch A, Stiles JK, Sutovsky P, Lai L, Im GS, Prather RS, Isom SC, Rucker E, Tsang BK. Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary. Biol Reprod. 2004 Jul; 71(1):282-90. PMID: 15028627.
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    49. Stiles JK, Whittaker J, Sarfo BY, Thompson WE, Powell MD, Bond VC. Trypanosome apoptotic factor mediates apoptosis in human brain vascular endothelial cells. Mol Biochem Parasitol. 2004 Feb; 133(2):229-40. PMID: 14698435.
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    50. Stiles JK, Kucerova Z, Sarfo B, Meade CA, Thompson W, Shah P, Xue L, Meade JC. Identification of surface-membrane P-type ATPases resembling fungal K(+)- and Na(+)-ATPases, in Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani. Ann Trop Med Parasitol. 2003 Jun; 97(4):351-66. PMID: 12831521.
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    51. Shah PH, Stiles JK, Finley RW, Lushbaugh WB, Meade JC. Trichomonas vaginalis: characterization of a family of P-type ATPase genes. Parasitol Int. 2002 Mar; 51(1):41-51. PMID: 11880226.
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    52. Stiles JK, Meade JC, Kucerova Z, Lyn D, Thompson W, Zakeri Z, Whittaker J. Trypanosoma brucei infection induces apoptosis and up-regulates neuroleukin expression in the cerebellum. Ann Trop Med Parasitol. 2001 Dec; 95(8):797-810. PMID: 11784434.
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    53. Meade JC, Li C, Stiles JK, Moate ME, Penny JI, Krishna S, Finley RW. The Trypanosoma cruzi genome contains ion motive ATPase genes which closely resemble Leishmania proton pumps. Parasitol Int. 2000 Dec; 49(4):309-20. PMID: 11077265.
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    54. Rogers PD, Stiles JK, Chapman SW, Cleary JD. Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1. J Infect Dis. 2000 Oct; 182(4):1280-3. PMID: 10979935.
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    55. Stiles JK, Shah PH, Xue L, Meade JC, Lushbaugh WB, Cleary JD, Finley RW. Molecular typing of Trichomonas vaginalis isolates by HSP70 restriction fragment length polymorphism. Am J Trop Med Hyg. 2000 Apr; 62(4):441-5. PMID: 11220758.
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    56. Stiles JK, Hicock PI, Shah PH, Meade JC. Genomic organization, transcription, splicing and gene regulation in Leishmania. Ann Trop Med Parasitol. 1999 Dec; 93(8):781-807. PMID: 10715672.
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    57. Stiles JK, Hicock PI, Kong L, Xue L, Meade JC. Leishmania donovani proton translocating P-type adenosine triphosphatases LDH1A and LDH1B: trans-splicing and polyadenylation of transcripts in amastigotes and promastigotes. Mol Biochem Parasitol. 1999 Sep 20; 103(1):105-9. PMID: 10514086.
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    58. Mihok S, Stiles JK, Mpanga E, Olubayo RO. Relationships between protease activity, host blood and infection rates in Glossina morsitans sspp. infected with Trypanosoma congolense, T. brucei and T. simiae. Med Vet Entomol. 1994 Jan; 8(1):47-50. PMID: 8161844.
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    59. Cummings KM, Stiles J, Mahoney MC, Sciandra R. Health and economic impact of cigarette smoking in New York State, 1987-1989. N Y State J Med. 1992 Nov; 92(11):469-73. PMID: 1488201.
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    60. Stiles JK, Ingram GA, Wallbanks KR, Molyneux DH, Maudlin I, Welburn S. Identification of midgut trypanolysin and trypanoagglutinin in Glossina palpalis sspp. (Diptera: Glossinidae). Parasitology. 1990 Dec; 101 Pt 3:369-76. PMID: 2092294.
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    61. Stiles JK, Wallbanks KR, Molyneux DH. Metacyclogenesis of Trypanosoma vivax in vitro: attachment to chitosan gel. Ann Trop Med Parasitol. 1990 Apr; 84(2):197-200. PMID: 2383099.
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