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Professor Georges Grau

TitleProfessor
InstitutionThe University of Sydney
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Latham SL, Tiberti N, Gokoolparsadh N, Holdaway K, Couraud PO, Grau GE, Combes V. Immuno-analysis of microparticles: probing at the limits of detection. Sci Rep. 2015 Nov 10; 5:16314. PMID: 26553743; PMCID: PMC4639787.
    2. Ampawong S, Chaisri U, Viriyavejakul P, Prapansilp P, Grau GE, Turner GD, Pongponratn E. A potential role for interleukin-33 and ?-epithelium sodium channel in the pathogenesis of human malaria associated lung injury. Malar J. 2015 Oct 05; 14:389. PMID: 26437894; PMCID: PMC4595310.
    3. Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA, Kim K. Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. MBio. 2015 Sep 22; 6(5):e01390-15. PMID: 26396242; PMCID: PMC4611030.
    4. Sorrell TC, Juillard PG, Djordjevic JT, Kaufman-Francis K, Dietmann A, Milonig A, Combes V, Grau GE. Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265. Microbes Infect. 2016 Jan; 18(1):57-67. PMID: 26369713.
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    5. Grau GE, Thompson MB, Murphy CR. VEGF: inflammatory paradoxes. Pathog Glob Health. 2015 Sep; 109(6):253-4. PMID: 26478002; PMCID: PMC4727579 [Available on 10/01/16].
    6. Whittington CM, Grau GE, Murphy CR, Thompson MB. Unusual angiogenic factor plays a role in lizard pregnancy but is not unique to viviparity. J Exp Zool B Mol Dev Evol. 2015 Mar; 324(2):152-8. PMID: 25732926.
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    7. Danastas K, Combes V, Lindsay LA, Grau GE, Thompson MB, Murphy CR. VEGF111: new insights in tissue invasion. Front Physiol. 2015; 6:2. PMID: 25657624; PMCID: PMC4302830.
    8. Kam A, Li KM, Razmovski-Naumovski V, Nammi S, Chan K, Grau GE, Li GQ. Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells. J Pharm Pharm Sci. 2015; 18(4):424-33. PMID: 26626244.
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    9. Wheway J, Latham SL, Combes V, Grau GE. Endothelial microparticles interact with and support the proliferation of T cells. J Immunol. 2014 Oct 01; 193(7):3378-87. PMID: 25187656; PMCID: PMC4170003.
    10. Hunt NH, Ball HJ, Hansen AM, Khaw LT, Guo J, Bakmiwewa S, Mitchell AJ, Combes V, Grau GE. Cerebral malaria: gamma-interferon redux. Front Cell Infect Microbiol. 2014; 4:113. PMID: 25177551; PMCID: PMC4133756.
    11. Khaw LT, Ball HJ, Mitchell AJ, Grau GE, Stocker R, Golenser J, Hunt NH. Brain endothelial cells increase the proliferation of Plasmodium falciparum through production of soluble factors. Exp Parasitol. 2014 Oct; 145:34-41. PMID: 25045850.
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    12. Pai S, Qin J, Cavanagh L, Mitchell A, El-Assaad F, Jain R, Combes V, Hunt NH, Grau GE, Weninger W. Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis. PLoS Pathog. 2014 Jul; 10(7):e1004236. PMID: 25033406; PMCID: PMC4102563.
    13. Ampawong S, Chaisri U, Viriyavejakul P, Nontprasert A, Grau GE, Pongponratn E. Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression. Int J Clin Exp Pathol. 2014; 7(5):2056-67. PMID: 24966914; PMCID: PMC4069908.
    14. El-Assaad F, Wheway J, Hunt NH, Grau GE, Combes V. Production, fate and pathogenicity of plasma microparticles in murine cerebral malaria. PLoS Pathog. 2014 Mar; 10(3):e1003839. PMID: 24651155; PMCID: PMC3961352.
    15. Wen B, Combes V, Bonhoure A, Weksler BB, Couraud PO, Grau GE. Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses. PLoS One. 2014; 9(3):e91597. PMID: 24646764; PMCID: PMC3960107.
    16. El-Assaad F, Combes V, Grau GE, Jambou R. Potential efficacy of citicoline as adjunct therapy in treatment of cerebral malaria. Antimicrob Agents Chemother. 2014; 58(1):602-5. PMID: 24165175; PMCID: PMC3910796.
    17. Liu H, Zhang W, Jia Y, Yu Q, Grau GE, Peng L, Ran Y, Yang Z, Deng H, Lou J. Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis. 2013 Oct 17; 4:e857. PMID: 24136221; PMCID: PMC3824650.
    18. Gong J, Luk F, Jaiswal R, George AM, Grau GE, Bebawy M. Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance. Eur J Pharmacol. 2013 Dec 05; 721(1-3):116-25. PMID: 24095666.
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    19. El-Assaad F, Wheway J, Mitchell AJ, Lou J, Hunt NH, Combes V, Grau GE. Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infect Immun. 2013 Nov; 81(11):3984-91. PMID: 23940206; PMCID: PMC3811819.
    20. Lu JF, Luk F, Gong J, Jaiswal R, Grau GE, Bebawy M. Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways. Pharmacol Res. 2013 Oct; 76:77-83. PMID: 23917219.
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    21. Khaw LT, Ball HJ, Golenser J, Combes V, Grau GE, Wheway J, Mitchell AJ, Hunt NH. Endothelial cells potentiate interferon-? production in a novel tripartite culture model of human cerebral malaria. PLoS One. 2013; 8(7):e69521. PMID: 23874969; PMCID: PMC3709908.
    22. Li CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, Grau GE, Combes V, Bebawy M, Gong J, Brammah S, Buckland ME, Suter CM. Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biol. 2013 Aug; 10(8):1333-44. PMID: 23807490; PMCID: PMC3817155.
    23. Dietmann A, Millonig A, Combes V, Couraud PO, Kachlany SC, Grau GE. Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells. Microb Pathog. 2013 Aug-Sep; 61-62:43-50. PMID: 23665198; PMCID: PMC3885975.
    24. Jaiswal R, Luk F, Dalla PV, Grau GE, Bebawy M. Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells. PLoS One. 2013; 8(4):e61515. PMID: 23593486; PMCID: PMC3625154.
    25. Razakandrainibe R, Combes V, Grau GE, Jambou R. Crossing the wall: the opening of endothelial cell junctions during infectious diseases. Int J Biochem Cell Biol. 2013 Jul; 45(7):1165-73. PMID: 23538297.
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    26. Wheway J, Obeid S, Couraud PO, Combes V, Grau GE. The brain microvascular endothelium supports T cell proliferation and has potential for alloantigen presentation. PLoS One. 2013; 8(1):e52586. PMID: 23320074; PMCID: PMC3540051.
    27. Roseblade A, Luk F, Rawling T, Ung A, Grau GE, Bebawy M. Cell-derived microparticles: new targets in the therapeutic management of disease. J Pharm Pharm Sci. 2013; 16(2):238-53. PMID: 23958193.
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    28. Walters SB, Kieckbusch J, Nagalingam G, Swain A, Latham SL, Grau GE, Britton WJ, Combes V, Saunders BM. Microparticles from mycobacteria-infected macrophages promote inflammation and cellular migration. J Immunol. 2013 Jan 15; 190(2):669-77. PMID: 23241892.
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    29. Latham SL, Chaponnier C, Dugina V, Couraud PO, Grau GE, Combes V. Cooperation between ß- and ?-cytoplasmic actins in the mechanical regulation of endothelial microparticle formation. FASEB J. 2013 Feb; 27(2):672-83. PMID: 23159932.
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    30. Hackett MJ, Lee J, El-Assaad F, McQuillan JA, Carter EA, Grau GE, Hunt NH, Lay PA. FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry. ACS Chem Neurosci. 2012 Dec 19; 3(12):1017-24. PMID: 23259037; PMCID: PMC3526967.
    31. Faille D, El-Assaad F, Mitchell AJ, Alessi MC, Chimini G, Fusai T, Grau GE, Combes V. Endocytosis and intracellular processing of platelet microparticles by brain endothelial cells. J Cell Mol Med. 2012 Aug; 16(8):1731-8. PMID: 21883894; PMCID: PMC3822686.
    32. Combes V, Guillemin GJ, Chan-Ling T, Hunt NH, Grau GE. The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. Trends Parasitol. 2012 Aug; 28(8):311-9. PMID: 22727810.
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    33. Jaiswal R, Luk F, Gong J, Mathys JM, Grau GE, Bebawy M. Microparticle conferred microRNA profiles--implications in the transfer and dominance of cancer traits. Mol Cancer. 2012 Jun 08; 11:37. PMID: 22682234; PMCID: PMC3499176.
    34. Razakandrainibe R, Pelleau S, Grau GE, Jambou R. Antigen presentation by endothelial cells: what role in the pathophysiology of malaria? Trends Parasitol. 2012 Apr; 28(4):151-60. PMID: 22365903.
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    35. Craig AG, Grau GE, Janse C, Kazura JW, Milner D, Barnwell JW, Turner G, Langhorne J. The role of animal models for research on severe malaria. PLoS Pathog. 2012 Feb; 8(2):e1002401. PMID: 22319438; PMCID: PMC3271056.
    36. Hafalla JC, Claser C, Couper KN, Grau GE, Renia L, de Souza JB, Riley EM. The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. PLoS Pathog. 2012 Feb; 8(2):e1002504. PMID: 22319445; PMCID: PMC3271068.
    37. Grau GE, Craig AG. Cerebral malaria pathogenesis: revisiting parasite and host contributions. Future Microbiol. 2012 Feb; 7(2):291-302. PMID: 22324996.
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    38. Ling ZL, Combes V, Grau GE, King NJ. Microparticles as immune regulators in infectious disease - an opinion. Front Immunol. 2011; 2:67. PMID: 22566856; PMCID: PMC3342294.
    39. Jambou R, El-Assaad F, Combes V, Grau GE. In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria. Malar J. 2011 Nov 25; 10:346. PMID: 22118493.
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    40. Jaiswal R, Gong J, Sambasivam S, Combes V, Mathys JM, Davey R, Grau GE, Bebawy M. Microparticle-associated nucleic acids mediate trait dominance in cancer. FASEB J. 2012 Jan; 26(1):420-9. PMID: 21965597.
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    41. Hempel C, Combes V, Hunt NH, Kurtzhals JA, Grau GE. CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin. Am J Pathol. 2011 Oct; 179(4):1939-50. PMID: 21854739; PMCID: PMC3181359.
    42. Ampawong S, Combes V, Hunt NH, Radford J, Chan-Ling T, Pongponratn E, Grau GE. Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. Int J Clin Exp Pathol. 2011 Aug 15; 4(6):566-74. PMID: 21904632; PMCID: PMC3160608.
    43. Gong J, Jaiswal R, Mathys JM, Combes V, Grau GE, Bebawy M. Microparticles and their emerging role in cancer multidrug resistance. Cancer Treat Rev. 2012 May; 38(3):226-34. PMID: 21757296.
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    44. Saggu R, Faille D, Grau GE, Cozzone PJ, Viola A. In the eye of experimental cerebral malaria. Am J Pathol. 2011 Sep; 179(3):1104-9. PMID: 21741941; PMCID: PMC3157263.
    45. Hackett MJ, McQuillan JA, El-Assaad F, Aitken JB, Levina A, Cohen DD, Siegele R, Carter EA, Grau GE, Hunt NH, Lay PA. Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. Analyst. 2011 Jul 21; 136(14):2941-52. PMID: 21629894.
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    46. Moxon CA, Grau GE, Craig AG. Malaria: modification of the red blood cell and consequences in the human host. Br J Haematol. 2011 Sep; 154(6):670-9. PMID: 21623767; PMCID: PMC3557659.
    47. Barbier M, Faille D, Loriod B, Textoris J, Camus C, Puthier D, Flori L, Wassmer SC, Victorero G, Alessi MC, Fusaï T, Nguyen C, Grau GE, Rihet P. Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria. PLoS One. 2011; 6(5):e19651. PMID: 21603600; PMCID: PMC3095604.
    48. El-Assaad F, Hempel C, Combes V, Mitchell AJ, Ball HJ, Kurtzhals JA, Hunt NH, Mathys JM, Grau GE. Differential microRNA expression in experimental cerebral and noncerebral malaria. Infect Immun. 2011 Jun; 79(6):2379-84. PMID: 21422175; PMCID: PMC3125837.
    49. Nantakomol D, Dondorp AM, Krudsood S, Udomsangpetch R, Pattanapanyasat K, Combes V, Grau GE, White NJ, Viriyavejakul P, Day NP, Chotivanich K. Circulating red cell-derived microparticles in human malaria. J Infect Dis. 2011 Mar 01; 203(5):700-6. PMID: 21282195; PMCID: PMC3072726.
    50. van der Heyde HC, Gramaglia I, Combes V, George TC, Grau GE. Flow cytometric analysis of microparticles. Methods Mol Biol. 2011; 699:337-54. PMID: 21116991.
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    51. Pankoui Mfonkeu JB, Gouado I, Fotso Kuaté H, Zambou O, Amvam Zollo PH, Grau GE, Combes V. Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria. PLoS One. 2010 Oct 14; 5(10):e13415. PMID: 20976232; PMCID: PMC2954805.
    52. Wassmer SC, Moxon CA, Taylor T, Grau GE, Molyneux ME, Craig AG. Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cell Microbiol. 2011 Feb; 13(2):198-209. PMID: 21029292; PMCID: PMC3041929.
    53. Hee L, Dinudom A, Mitchell AJ, Grau GE, Cook DI, Hunt NH, Ball HJ. Reduced activity of the epithelial sodium channel in malaria-induced pulmonary oedema in mice. Int J Parasitol. 2011 Jan; 41(1):81-8. PMID: 20816846.
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    54. McQuillan JA, Mitchell AJ, Ho YF, Combes V, Ball HJ, Golenser J, Grau GE, Hunt NH. Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. Int J Parasitol. 2011 Feb; 41(2):155-63. PMID: 20828575.
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    55. Carpintero R, Gruaz L, Brandt KJ, Scanu A, Faille D, Combes V, Grau GE, Burger D. HDL interfere with the binding of T cell microparticles to human monocytes to inhibit pro-inflammatory cytokine production. PLoS One. 2010 Jul 29; 5(7):e11869. PMID: 20686620; PMCID: PMC2912329.
    56. Jambou R, Combes V, Jambou MJ, Weksler BB, Couraud PO, Grau GE. Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions. PLoS Pathog. 2010 Jul 29; 6(7):e1001021. PMID: 20686652; PMCID: PMC2912387.
    57. Mfonkeu JB, Gouado I, Kuaté HF, Zambou O, Combes V, Grau GE, Zollo PH. Biochemical markers of nutritional status and childhood malaria severity in Cameroon. Br J Nutr. 2010 Sep; 104(6):886-92. PMID: 20615271.
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    58. Mitchell AJ, Pradel LC, Chasson L, Van Rooijen N, Grau GE, Hunt NH, Chimini G. Technical advance: autofluorescence as a tool for myeloid cell analysis. J Leukoc Biol. 2010 Sep; 88(3):597-603. PMID: 20534703.
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    59. Hunt NH, Grau GE, Engwerda C, Barnum SR, van der Heyde H, Hansen DS, Schofield L, Golenser J. Murine cerebral malaria: the whole story. Trends Parasitol. 2010 Jun; 26(6):272-4. PMID: 20382078.
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    60. Combes V, El-Assaad F, Faille D, Jambou R, Hunt NH, Grau GE. Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Prog Neurobiol. 2010 Jun; 91(2):140-51. PMID: 20117166.
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    61. Couper KN, Barnes T, Hafalla JC, Combes V, Ryffel B, Secher T, Grau GE, Riley EM, de Souza JB. Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. PLoS Pathog. 2010 Jan 29; 6(1):e1000744. PMID: 20126448; PMCID: PMC2813278.
    62. Faille D, El-Assaad F, Alessi MC, Fusai T, Combes V, Grau GE. Platelet-endothelial cell interactions in cerebral malaria: the end of a cordial understanding. Thromb Haemost. 2009 Dec; 102(6):1093-102. PMID: 19967139.
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    63. Gouado I, Pankoui M JB, Fotso K H, Zambou O, Nguélé S, Combes V, Grau GE, Amvam Z PH. Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon. Pediatr Infect Dis J. 2009 Dec; 28(12):1081-4. PMID: 19935269.
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    64. Bridges DJ, Bunn J, van Mourik JA, Grau G, Preston RJ, Molyneux M, Combes V, O'Donnell JS, de Laat B, Craig A. Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings. Blood. 2010 Feb 18; 115(7):1472-4. PMID: 19897581; PMCID: PMC2840836.
    65. Zhang WJ, Wu LQ, Liu HL, Ye LY, Xin YL, Grau GE, Lou JN. Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation. Microvasc Res. 2009 Dec; 78(3):379-85. PMID: 19729028.
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    66. Faille D, Combes V, Mitchell AJ, Fontaine A, Juhan-Vague I, Alessi MC, Chimini G, Fusaï T, Grau GE. Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium. FASEB J. 2009 Oct; 23(10):3449-58. PMID: 19535685.
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    67. Bechah Y, Capo C, Grau G, Raoult D, Mege JL. Rickettsia prowazekii infection of endothelial cells increases leukocyte adhesion through alphavbeta3 integrin engagement. Clin Microbiol Infect. 2009 Dec; 15 Suppl 2:249-50. PMID: 19438625.
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    68. Bebawy M, Combes V, Lee E, Jaiswal R, Gong J, Bonhoure A, Grau GE. Membrane microparticles mediate transfer of P-glycoprotein to drug sensitive cancer cells. Leukemia. 2009 Sep; 23(9):1643-9. PMID: 19369960.
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    69. Larkin D, de Laat B, Jenkins PV, Bunn J, Craig AG, Terraube V, Preston RJ, Donkor C, Grau GE, van Mourik JA, O'Donnell JS. Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. PLoS Pathog. 2009 Mar; 5(3):e1000349. PMID: 19300493; PMCID: PMC2652105.
    70. Bruzzone R, Dubois-Dalcq M, Grau GE, Griffin DE, Kristensson K. Infectious diseases of the nervous system and their impact in developing countries. PLoS Pathog. 2009 Feb; 5(2):e1000199. PMID: 19247436; PMCID: PMC2642628.
    71. Jambou R, El-Assaad F, Combes V, Grau GE. Citicoline (CDP-choline): What role in the treatment of complications of infectious diseases. Int J Biochem Cell Biol. 2009 Jul; 41(7):1467-70. PMID: 19401146.
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    72. Mfonkeu JB, Gouado I, Kuate HF, Zambou O, Grau G, Combes V, Zollo PH. Clinical presentation, haematological indices and management of children with severe and uncomplicated malaria in Douala, Cameroon. Pak J Biol Sci. 2008 Oct 15; 11(20):2401-6. PMID: 19137849.
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    73. Ramaswamy Y, Wu C, Van Hummel A, Combes V, Grau G, Zreiqat H. The responses of osteoblasts, osteoclasts and endothelial cells to zirconium modified calcium-silicate-based ceramic. Biomaterials. 2008 Nov; 29(33):4392-402. PMID: 18757093.
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    74. Togbe D, de Sousa PL, Fauconnier M, Boissay V, Fick L, Scheu S, Pfeffer K, Menard R, Grau GE, Doan BT, Beloeil JC, Renia L, Hansen AM, Ball HJ, Hunt NH, Ryffel B, Quesniaux VF. Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PLoS One. 2008 Jul 09; 3(7):e2608. PMID: 18612394; PMCID: PMC2442868.
    75. von Zur Muhlen C, Sibson NR, Peter K, Campbell SJ, Wilainam P, Grau GE, Bode C, Choudhury RP, Anthony DC. A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI. J Clin Invest. 2008 Mar; 118(3):1198-207. PMID: 18274670; PMCID: PMC2242620.
    76. Penet MF, Abou-Hamdan M, Coltel N, Cornille E, Grau GE, de Reggi M, Gharib B. Protection against cerebral malaria by the low-molecular-weight thiol pantethine. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1321-6. PMID: 18195363; PMCID: PMC2234136.
    77. Wassmer SC, Taylor T, Maclennan CA, Kanjala M, Mukaka M, Molyneux ME, Grau GE. Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopenia. J Infect Dis. 2008 Jan 01; 197(1):72-8. PMID: 18171288; PMCID: PMC2570538.
    78. Delahaye NF, Coltel N, Puthier D, Barbier M, Benech P, Joly F, Iraqi FA, Grau GE, Nguyen C, Rihet P. Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. BMC Genomics. 2007 Dec 06; 8:452. PMID: 18062806; PMCID: PMC2246131.
    79. Niu JX, Zhang WJ, Ye LY, Wu LQ, Zhu GJ, Yang ZH, Grau GE, Lou JN. The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion. Eur J Cancer Prev. 2007 Dec; 16(6):517-27. PMID: 18090124.
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    80. Wu LQ, Zhang WJ, Niu JX, Ye LY, Yang ZH, Grau GE, Lou JN. Phenotypic and functional differences between human liver cancer endothelial cells and liver sinusoidal endothelial cells. J Vasc Res. 2008; 45(1):78-86. PMID: 17901709.
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    81. Togbe D, Schofield L, Grau GE, Schnyder B, Boissay V, Charron S, Rose S, Beutler B, Quesniaux VF, Ryffel B. Murine cerebral malaria development is independent of toll-like receptor signaling. Am J Pathol. 2007 May; 170(5):1640-8. PMID: 17456769; PMCID: PMC1854958.
    82. Bechah Y, Capo C, Grau GE, Raoult D, Mege JL. A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus. Microbes Infect. 2007 Jun; 9(7):898-906. PMID: 17537665.
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    83. Penet MF, Kober F, Confort-Gouny S, Le Fur Y, Dalmasso C, Coltel N, Liprandi A, Gulian JM, Grau GE, Cozzone PJ, Viola A. Magnetic resonance spectroscopy reveals an impaired brain metabolic profile in mice resistant to cerebral malaria infected with Plasmodium berghei ANKA. J Biol Chem. 2007 May 11; 282(19):14505-14. PMID: 17369263.
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    84. Meghari S, Desnues B, Capo C, Grau GE, Raoult D, Mege JL. Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever. Eur Cytokine Netw. 2006 Dec; 17(4):253-9. PMID: 17353158.
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    85. Zhang WJ, Ye LY, Wu LQ, Xin YL, Gu F, Niu JX, Yang ZH, Zhu GJ, Grau GE, Lou JN. Morphologic, phenotypic and functional characteristics of endothelial cells derived from human hepatic cavernous hemangioma. J Vasc Res. 2006; 43(6):522-32. PMID: 17008795.
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    86. van der Heyde HC, Nolan J, Combes V, Gramaglia I, Grau GE. A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends Parasitol. 2006 Nov; 22(11):503-8. PMID: 16979941.
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    87. Golenser J, Waknine JH, Krugliak M, Hunt NH, Grau GE. Current perspectives on the mechanism of action of artemisinins. Int J Parasitol. 2006 Dec; 36(14):1427-41. PMID: 17005183.
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    88. Coltel N, Combes V, Wassmer SC, Chimini G, Grau GE. Cell vesiculation and immunopathology: implications in cerebral malaria. Microbes Infect. 2006 Jul; 8(8):2305-16. PMID: 16829152.
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    89. Wassmer SC, Cianciolo GJ, Combes V, Grau GE. [LMP-420, a new therapeutic approach for cerebral malaria?]. Med Sci (Paris). 2006 Apr; 22(4):343-5. PMID: 16597395.
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    90. Combes V, Coltel N, Faille D, Wassmer SC, Grau GE. Cerebral malaria: role of microparticles and platelets in alterations of the blood-brain barrier. Int J Parasitol. 2006 May 01; 36(5):541-6. PMID: 16600245.
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    91. Peyrefitte CN, Pastorino B, Grau GE, Lou J, Tolou H, Couissinier-Paris P. Dengue virus infection of human microvascular endothelial cells from different vascular beds promotes both common and specific functional changes. J Med Virol. 2006 Feb; 78(2):229-42. PMID: 16372301.
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    92. Wassmer SC, de Souza JB, Frère C, Candal FJ, Juhan-Vague I, Grau GE. TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. J Immunol. 2006 Jan 15; 176(2):1180-4. PMID: 16394007.
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    93. Wassmer SC, Combes V, Candal FJ, Juhan-Vague I, Grau GE. Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum. Infect Immun. 2006 Jan; 74(1):645-53. PMID: 16369021; PMCID: PMC1346683.
    94. Meghari S, Rolain JM, Grau GE, Platt E, Barrassi L, Mege JL, Raoult D. Antiangiogenic effect of erythromycin: an in vitro model of Bartonella quintana infection. J Infect Dis. 2006 Feb 01; 193(3):380-6. PMID: 16388485.
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    95. Delahaye NF, Coltel N, Puthier D, Flori L, Houlgatte R, Iraqi FA, Nguyen C, Grau GE, Rihet P. Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice. J Infect Dis. 2006 Jan 15; 193(2):312-21. PMID: 16362897.
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    96. Schofield L, Grau GE. Immunological processes in malaria pathogenesis. Nat Rev Immunol. 2005 Sep; 5(9):722-35. PMID: 16138104.
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    97. Wassmer SC, Cianciolo GJ, Combes V, Grau GE. Inhibition of endothelial activation: a new way to treat cerebral malaria? PLoS Med. 2005 Sep; 2(9):e245. PMID: 16104828; PMCID: PMC1188254.
    98. Penet MF, Viola A, Confort-Gouny S, Le Fur Y, Duhamel G, Kober F, Ibarrola D, Izquierdo M, Coltel N, Gharib B, Grau GE, Cozzone PJ. Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema. J Neurosci. 2005 Aug 10; 25(32):7352-8. PMID: 16093385.
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    99. Grau GE, Chimini G. Immunopathological consequences of the loss of engulfment genes: the case of ABCA1. J Soc Biol. 2005; 199(3):199-206. PMID: 16471259.
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    100. Combes V, Coltel N, Alibert M, van Eck M, Raymond C, Juhan-Vague I, Grau GE, Chimini G. ABCA1 gene deletion protects against cerebral malaria: potential pathogenic role of microparticles in neuropathology. Am J Pathol. 2005 Jan; 166(1):295-302. PMID: 15632021; PMCID: PMC1602289.
    101. Rogerson SJ, Grau GE, Hunt NH. The microcirculation in severe malaria. Microcirculation. 2004 Oct-Nov; 11(7):559-76. PMID: 15513866.
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    102. Combes V, Taylor TE, Juhan-Vague I, Mège JL, Mwenechanya J, Tembo M, Grau GE, Molyneux ME. Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma. JAMA. 2004 Jun 02; 291(21):2542-4. PMID: 15173142.
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    103. Coltel N, Combes V, Hunt NH, Grau GE. Cerebral malaria -- a neurovascular pathology with many riddles still to be solved. Curr Neurovasc Res. 2004 Apr; 1(2):91-110. PMID: 16185187.
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    104. Combes V, Rosenkranz AR, Redard M, Pizzolato G, Lepidi H, Vestweber D, Mayadas TN, Grau GE. Pathogenic role of P-selectin in experimental cerebral malaria: importance of the endothelial compartment. Am J Pathol. 2004 Mar; 164(3):781-6. PMID: 14982832; PMCID: PMC1613268.
    105. Wassmer SC, Lépolard C, Traoré B, Pouvelle B, Gysin J, Grau GE. Platelets reorient Plasmodium falciparum-infected erythrocyte cytoadhesion to activated endothelial cells. J Infect Dis. 2004 Jan 15; 189(2):180-9. PMID: 14722881.
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    106. Combes V, Grau GE. ["Molecular approaches to malaria" (MAM 2004) Lorne-Victoria, Australia, February 1-5, 2004]. Med Trop (Mars). 2004; 64(4):401-4. PMID: 15615397.
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    107. Hunt NH, Grau GE. Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol. 2003 Sep; 24(9):491-9. PMID: 12967673.
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    108. Wassmer SC, Combes V, Grau GE. Pathophysiology of cerebral malaria: role of host cells in the modulation of cytoadhesion. Ann N Y Acad Sci. 2003 May; 992:30-8. PMID: 12794044.
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    109. Grau GE, Mackenzie CD, Carr RA, Redard M, Pizzolato G, Allasia C, Cataldo C, Taylor TE, Molyneux ME. Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria. J Infect Dis. 2003 Feb 01; 187(3):461-6. PMID: 12552430.
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    110. Wassmer SC, Coltel N, Combes V, Grau GE. [Pathogenesis of cerebral malaria: facts and hypotheses]. Med Trop (Mars). 2003; 63(3):254-7. PMID: 14579462.
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    111. Dou L, Cerini C, Brunet P, Guilianelli C, Moal V, Grau G, De Smet R, Vanholder R, Sampol J, Berland Y. P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines. Kidney Int. 2002 Dec; 62(6):1999-2009. PMID: 12427124.
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    112. Stoelcker B, Hehlgans T, Weigl K, Bluethmann H, Grau GE, Männel DN. Requirement for tumor necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria. Infect Immun. 2002 Oct; 70(10):5857-9. PMID: 12228317; PMCID: PMC128326.
    113. Hamacher J, Lucas R, Lijnen HR, Buschke S, Dunant Y, Wendel A, Grau GE, Suter PM, Ricou B. Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 2002 Sep 01; 166(5):651-6. PMID: 12204860.
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    114. Lou J, Lucas R, Grau GE. Pathogenesis of cerebral malaria: recent experimental data and possible applications for humans. Clin Microbiol Rev. 2001 Oct; 14(4):810-20, table of contents. PMID: 11585786; PMCID: PMC89004.
    115. Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE, Vadas L, Pugin J. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med. 2001 Aug 01; 164(3):396-402. PMID: 11500339.
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    116. Lucas R, Montesano R, Pepper MS, Hafner M, Sablon E, Dunant Y, Grau GE, De Baetselier P, Männel D, Fransen L. Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. Int J Cancer. 2001 Feb 15; 91(4):543-9. PMID: 11251979.
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    117. Banit DM, Grau G, Fisher JR. Evaluation of the acute cervical spine: a management algorithm. J Trauma. 2000 Sep; 49(3):450-6. PMID: 11003322.
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    118. Piguet PF, Da Laperrousaz C, Vesin C, Tacchini-Cottier F, Senaldi G, Grau GE. Delayed mortality and attenuated thrombocytopenia associated with severe malaria in urokinase- and urokinase receptor-deficient mice. Infect Immun. 2000 Jul; 68(7):3822-9. PMID: 10858190; PMCID: PMC101654.
    119. Dellacasagrande J, Moulin PA, Guilianelli C, Capo C, Raoult D, Grau GE, Mege JL. Reduced transendothelial migration of monocytes infected by Coxiella burnetii. Infect Immun. 2000 Jun; 68(6):3784-6. PMID: 10816549; PMCID: PMC97680.
    120. Dignat-George F, Tissot-Dupont H, Grau GE, Camoin-Jau L, Raoult D, Sampol J. Differences in levels of soluble E-selectin and VCAM-1 in malignant versus non malignant Mediterranean spotted fever. Thromb Haemost. 1999 Dec; 82(6):1610-3. PMID: 10613643.
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    121. Hribar M, Bloc A, van der Goot FG, Fransen L, De Baetselier P, Grau GE, Bluethmann H, Matthay MA, Dunant Y, Pugin J, Lucas R. The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages. Eur J Immunol. 1999 Oct; 29(10):3105-11. PMID: 10540321.
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    122. Lou J, Gasche Y, Zheng L, Giroud C, Morel P, Clements J, Ythier A, Grau GE. Interferon-beta inhibits activated leukocyte migration through human brain microvascular endothelial cell monolayer. Lab Invest. 1999 Aug; 79(8):1015-25. PMID: 10462039.
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    123. Nieswandt B, Echtenacher B, Wachs FP, Schröder J, Gessner JE, Schmidt RE, Grau GE, Männel DN. Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice. Blood. 1999 Jul 15; 94(2):684-93. PMID: 10397735.
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    124. Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F. In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. J Clin Invest. 1999 Jul; 104(1):93-102. PMID: 10393703; PMCID: PMC408397.
    125. Berney T, Gasche Y, Robert J, Jenny A, Mensi N, Grau G, Vermeulen B, Morel P. Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis. Pancreas. 1999 May; 18(4):371-7. PMID: 10231842.
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    126. Lucas R, Holmgren L, Garcia I, Jimenez B, Mandriota SJ, Borlat F, Sim BK, Wu Z, Grau GE, Shing Y, Soff GA, Bouck N, Pepper MS. Multiple forms of angiostatin induce apoptosis in endothelial cells. Blood. 1998 Dec 15; 92(12):4730-41. PMID: 9845539.
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    127. Lou J, Gasche Y, Zheng L, Critico B, Monso-Hinard C, Juillard P, Morel P, Buurman WA, Grau GE. Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria. Eur J Immunol. 1998 Dec; 28(12):3989-4000. PMID: 9862335.
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    128. Lucas R, Garcia I, Donati YR, Hribar M, Mandriota SJ, Giroud C, Buurman WA, Fransen L, Suter PM, Nunez G, Pepper MS, Grau GE. Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells. Eur J Immunol. 1998 Nov; 28(11):3577-86. PMID: 9842900.
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    129. Lou JN, Mili N, Decrind C, Donati Y, Kossodo S, Spiliopoulos A, Ricou B, Suter PM, Morel DR, Morel P, Grau GE. An improved method for isolation of microvascular endothelial cells from normal and inflamed human lung. In Vitro Cell Dev Biol Anim. 1998 Jul-Aug; 34(7):529-36. PMID: 9719412.
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    130. Lou J, Bühler L, Deng S, Mentha G, Montesano R, Grau GE, Morel P. Inhibition of leukocyte adherence and transendothelial migration in cultured human liver vascular endothelial cells by prostaglandin E1. Hepatology. 1998 Mar; 27(3):822-8. PMID: 9500713.
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    131. Duport S, Robert F, Muller D, Grau G, Parisi L, Stoppini L. An in vitro blood-brain barrier model: cocultures between endothelial cells and organotypic brain slice cultures. Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4):1840-5. PMID: 9465104; PMCID: PMC19200.
    132. Karunaweera ND, Carter R, Grau GE, Mendis KN. Demonstration of anti-disease immunity to Plasmodium vivax malaria in Sri Lanka using a quantitative method to assess clinical disease. Am J Trop Med Hyg. 1998 Feb; 58(2):204-10. PMID: 9502605.
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    133. Carota A, Pizzolato GP, Redard M, Gailloud P, Grau GE. Adhesion molecules in HIV-related and idiopathic polymyositis: immunohistochemical studies. Clin Neuropathol. 1997 Nov-Dec; 16(6):312-8. PMID: 9401798.
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    134. Lou J, Donati YR, Juillard P, Giroud C, Vesin C, Mili N, Grau GE. Platelets play an important role in TNF-induced microvascular endothelial cell pathology. Am J Pathol. 1997 Nov; 151(5):1397-405. PMID: 9358766; PMCID: PMC1858065.
    135. Grau GE, Maennel DN. TNF inhibition and sepsis -- sounding a cautionary note. Nat Med. 1997 Nov; 3(11):1193-5. PMID: 9359687.
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    136. Chofflon M, Roth S, Juillard C, Paunier AM, Juillard P, Degroote D, Grau GE. Tumor necrosis factor production capacity as a potentially useful parameter to monitor disease activity in multiple sclerosis. Eur Cytokine Netw. 1997 Sep; 8(3):253-7. PMID: 9346357.
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    137. Monso-Hinard C, Lou JN, Behr C, Juillard P, Grau GE. Expression of major histocompatibility complex antigens on mouse brain microvascular endothelial cells in relation to susceptibility to cerebral malaria. Immunology. 1997 Sep; 92(1):53-9. PMID: 9370924; PMCID: PMC1363981.
    138. Männel DN, Grau GE. Role of platelet adhesion in homeostasis and immunopathology. Mol Pathol. 1997 Aug; 50(4):175-85. PMID: 9350300; PMCID: PMC379623.
    139. Kossodo S, Monso C, Juillard P, Velu T, Goldman M, Grau GE. Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology. 1997 Aug; 91(4):536-40. PMID: 9378491; PMCID: PMC1363872.
    140. Lou J, Ythier A, Burger D, Zheng L, Juillard P, Lucas R, Dayer JM, Grau GE. Modulation of soluble and membrane-bound TNF-induced phenotypic and functional changes of human brain microvascular endothelial cells by recombinant TNF binding protein I. J Neuroimmunol. 1997 Jul; 77(1):107-15. PMID: 9209275.
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    141. Lucas R, Juillard P, Decoster E, Redard M, Burger D, Donati Y, Giroud C, Monso-Hinard C, De Kesel T, Buurman WA, Moore MW, Dayer JM, Fiers W, Bluethmann H, Grau GE. Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria. Eur J Immunol. 1997 Jul; 27(7):1719-25. PMID: 9247583.
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    142. Lucas R, Echtenacher B, Sablon E, Juillard P, Magez S, Lou J, Donati Y, Bosman F, Van de Voorde A, Fransen L, Männel DN, Grau GE, de Baetselier P. Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity. Infect Immun. 1997 Jun; 65(6):2006-10. PMID: 9169725; PMCID: PMC175277.
    143. Lucas R, Lou J, Morel DR, Ricou B, Suter PM, Grau GE. TNF receptors in the microvascular pathology of acute respiratory distress syndrome and cerebral malaria. J Leukoc Biol. 1997 May; 61(5):551-8. PMID: 9129203.
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    144. Mordmüller BG, Metzger WG, Juillard P, Brinkman BM, Verweij CL, Grau GE, Kremsner PG. Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance. Eur Cytokine Netw. 1997 Mar; 8(1):29-35. PMID: 9110145.
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    145. Grau GE, de Moerloose P, Bulla O, Lou J, Lei Z, Reber G, Mili N, Ricou B, Morel DR, Suter PM. Haemostatic properties of human pulmonary and cerebral microvascular endothelial cells. Thromb Haemost. 1997 Mar; 77(3):585-90. PMID: 9066014.
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    146. Burger D, Lou J, Dayer JM, Grau GE. Both soluble and membrane-associated TNF activate brain microvascular endothelium: relevance to multiple sclerosis. Mol Psychiatry. 1997 Mar; 2(2):113-6. PMID: 9106230.
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    147. Lou J, Chofflon M, Juillard C, Donati Y, Mili N, Siegrist CA, Grau GE. Brain microvascular endothelial cells and leukocytes derived from patients with multiple sclerosis exhibit increased adhesion capacity. Neuroreport. 1997 Feb 10; 8(3):629-33. PMID: 9106736.
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    148. Lucas R, Lou JN, Juillard P, Moore M, Bluethmann H, Grau GE. Respective role of TNF receptors in the development of experimental cerebral malaria. J Neuroimmunol. 1997 Feb; 72(2):143-8. PMID: 9042106.
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    149. Ravi V, Parida S, Desai A, Chandramuki A, Gourie-Devi M, Grau GE. Correlation of tumor necrosis factor levels in the serum and cerebrospinal fluid with clinical outcome in Japanese encephalitis patients. J Med Virol. 1997 Feb; 51(2):132-6. PMID: 9021544.
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    150. Lou J, Dayer JM, Grau GE, Burger D. Direct cell/cell contact with stimulated T lymphocytes induces the expression of cell adhesion molecules and cytokines by human brain microvascular endothelial cells. Eur J Immunol. 1996 Dec; 26(12):3107-13. PMID: 8977311.
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    151. Sekine-Okano M, Lucas R, Rungger D, De Kesel T, Grau GE, Leuenberger PM, Rungger-Brändle E. Expression and release of tumor necrosis factor-alpha by explants of mouse cornea. Invest Ophthalmol Vis Sci. 1996 Jun; 37(7):1302-10. PMID: 8641833.
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    152. Deng S, Pascual M, Lou J, Bühler L, Wessel HP, Grau G, Schifferli JA, Morel P. New synthetic sulfated oligosaccharides prolong survival of cardiac xenografts by inhibiting release of heparan sulfate from endothelial cells. Transplantation. 1996 May 15; 61(9):1300-5. PMID: 8629287.
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    153. Le Roy D, Morand P, Lengacher S, Celio M, Grau GE, Glauser MP, Heumann D. Streptococcus mitis cell walls and lipopolysaccharide induce lethality in D-galactosamine-sensitized mice by a tumor necrosis factor-dependent pathway. Infect Immun. 1996 May; 64(5):1846-9. PMID: 8613401; PMCID: PMC174002.
    154. Grau GE, Mili N, Lou JN, Morel DR, Ricou B, Lucas R, Suter PM. Phenotypic and functional analysis of pulmonary microvascular endothelial cells from patients with acute respiratory distress syndrome. Lab Invest. 1996 Apr; 74(4):761-70. PMID: 8606486.
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    155. Borrelli E, Roux-Lombard P, Grau GE, Girardin E, Ricou B, Dayer J, Suter PM. Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk. Crit Care Med. 1996 Mar; 24(3):392-7. PMID: 8625625.
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    156. Kremsner PG, Winkler S, Brandts C, Wildling E, Jenne L, Graninger W, Prada J, Bienzle U, Juillard P, Grau GE. Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production. Am J Trop Med Hyg. 1995 Nov; 53(5):532-8. PMID: 7485713.
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    157. Benador NM, Grau GE, Ruef C, Girardin EP. Endogenous TNF-alpha modulates the proliferation of rat mesangial cells and their prostaglandin E2 synthesis. Microvasc Res. 1995 Sep; 50(2):154-61. PMID: 8538496.
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    158. Garcia I, Miyazaki Y, Araki K, Araki M, Lucas R, Grau GE, Milon G, Belkaid Y, Montixi C, Lesslauer W, et al. Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections. Eur J Immunol. 1995 Aug; 25(8):2401-7. PMID: 7664802.
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    159. Tacchini-Cottier F, Lou JN, Roberts DJ, Garcia AM, Grau GE. Detection of a LFA-1-like epitope on the surface of erythrocytes infected with a strain of Plasmodium falciparum. Immunology. 1995 Jun; 85(2):205-13. PMID: 7543875; PMCID: PMC1383882.
    160. de Kossodo S, Houba V, Grau GE. Assaying tumor necrosis factor concentrations in human serum. A WHO International Collaborative study. J Immunol Methods. 1995 May 11; 182(1):107-14. PMID: 7769238.
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    161. Grau GE, Lou JN. Experimental cerebral malaria: possible new mechanisms in the TNF-induced microvascular pathology. Soz Praventivmed. 1995; 40(1):50-7. PMID: 7900436.
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    162. van de Kar NC, Sauerwein RW, Demacker PN, Grau GE, van Hinsbergh VW, Monnens LA. Plasma cytokine levels in hemolytic uremic syndrome. Nephron. 1995; 71(3):309-13. PMID: 8569980.
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    163. Rizzoli R, Feyen JH, Grau G, Wohlwend A, Sappino AP, Bonjour JP. Regulation of parathyroid hormone-related protein production in a human lung squamous cell carcinoma line. J Endocrinol. 1994 Nov; 143(2):333-41. PMID: 7829996.
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    164. Grau GE, de Kossodo S. Cerebral malaria: mediators, mechanical obstruction or more? Parasitol Today. 1994 Oct; 10(10):408-9. PMID: 15275551.
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    165. Grau GE, Männel DN. Strategies for inhibition of tumor necrosis factor in vivo. Trends Microbiol. 1994 Sep; 2(9):303-5. PMID: 7812661.
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    166. Grau GE, Behr C. T cells and malaria: is Th1 cell activation a prerequisite for pathology? Res Immunol. 1994 Jul-Aug; 145(6):441-54. PMID: 7899710.
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    167. Müller KM, Lisby S, Arrighi JF, Grau GE, Saurat JH, Hauser C. H-2D haplotype-linked expression and involvement of TNF-alpha in Th2 cell-mediated tissue inflammation. J Immunol. 1994 Jul 01; 153(1):316-24. PMID: 8207244.
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    168. Deng S, Bühler L, Lou J, Grau G, Redard M, Bubloz C, Rohner A, Morel P. Study of concordant xenografted islets of Langerhans rejection: humoral or cellular mechanism? Transplant Proc. 1994 Jun; 26(3):1184-5. PMID: 8029879.
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    169. Senaldi G, Pointaire P, Piguet PF, Grau GE. Protective effect of N-acetylcysteine in hapten-induced irritant and contact hypersensitivity reactions. J Invest Dermatol. 1994 Jun; 102(6):934-7. PMID: 8006457.
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    170. Ferran C, Dautry F, Mérite S, Sheehan K, Schreiber R, Grau G, Bach JF, Chatenoud L. Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo. J Clin Invest. 1994 May; 93(5):2189-96. PMID: 8182150; PMCID: PMC294360.
    171. de Kossodo S, Grau GE, Louis JA, Müller I. Tumor necrosis factor alpha (TNF-alpha) and TNF-beta and their receptors in experimental cutaneous leishmaniasis. Infect Immun. 1994 Apr; 62(4):1414-20. PMID: 8132347; PMCID: PMC186296.
    172. Senaldi G, Vesin C, Chang R, Grau GE, Piguet PF. Role of polymorphonuclear neutrophil leukocytes and their integrin CD11a (LFA-1) in the pathogenesis of severe murine malaria. Infect Immun. 1994 Apr; 62(4):1144-9. PMID: 8132319; PMCID: PMC186241.
    173. de Kossodo S, Critico B, Grau GE. Modulation of the transcripts for tumor necrosis factor-alpha and its receptors in vivo. Eur J Immunol. 1994 Mar; 24(3):769-72. PMID: 8125144.
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    174. Girardin E, Grau GE, Paunier L, Le Coultre C. Early hemodynamic and renal effects of tumor necrosis factor alpha: role of thromboxane. Circ Shock. 1994 Jan; 42(1):20-6. PMID: 8149506.
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    175. Tacchini-Cottier F, Grau GE. [Cytokines and malaria]. Med Trop (Mars). 1994; 54(3):257-62. PMID: 7885208.
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    176. Bienvenu J, Coulon L, Doche C, Gutowski MC, Grau GE. Analytical performances of commercial ELISA-kits for IL-2, IL-6 and TNF-alpha. A WHO study. Eur Cytokine Netw. 1993 Nov-Dec; 4(6):447-51. PMID: 8186376.
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    177. Molyneux ME, Engelmann H, Taylor TE, Wirima JJ, Aderka D, Wallach D, Grau GE. Circulating plasma receptors for tumour necrosis factor in Malawian children with severe falciparum malaria. Cytokine. 1993 Nov; 5(6):604-9. PMID: 8186373.
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    178. de Kossodo S, Grau GE. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J Immunol. 1993 Nov 01; 151(9):4811-20. PMID: 8409439.
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    179. Grau GE, Tacchini-Cottier F, Vesin C, Milon G, Lou JN, Piguet PF, Juillard P. TNF-induced microvascular pathology: active role for platelets and importance of the LFA-1/ICAM-1 interaction. Eur Cytokine Netw. 1993 Nov-Dec; 4(6):415-9. PMID: 7910490.
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    180. Beutler B, Grau GE. Tumor necrosis factor in the pathogenesis of infectious diseases. Crit Care Med. 1993 Oct; 21(10 Suppl):S423-35. PMID: 8403980.
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    181. Piguet PF, Vesin C, Ryser JE, Senaldi G, Grau GE, Tacchini-Cottier F. An effector role for platelets in systemic and local lipopolysaccharide-induced toxicity in mice, mediated by a CD11a- and CD54-dependent interaction with endothelium. Infect Immun. 1993 Oct; 61(10):4182-7. PMID: 8104895; PMCID: PMC281142.
    182. De Groote D, Grau GE, Dehart I, Franchimont P. Stabilisation of functional tumor necrosis factor-alpha by its soluble TNF receptors. Eur Cytokine Netw. 1993 Sep-Oct; 4(5):359-62. PMID: 8117937.
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    183. Ythier A, Gascon MP, Juillard P, Vesin C, Wallach D, Grau GE. Protective effect of natural TNF-binding protein on human TNF-induced toxicity in mice. Cytokine. 1993 Sep; 5(5):459-62. PMID: 8142601.
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    184. Piguet PF, Ribaux C, Karpuz V, Grau GE, Kapanci Y. Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis. Am J Pathol. 1993 Sep; 143(3):651-5. PMID: 8362967; PMCID: PMC1887194.
    185. Piguet PF, Grau GE, de Kossodo S. Role of granulocyte-macrophage colony-stimulating factor in pulmonary fibrosis induced in mice by bleomycin. Exp Lung Res. 1993 Sep-Oct; 19(5):579-87. PMID: 7504622.
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    186. Egan JE, Hoffman SL, Haynes JD, Sadoff JC, Schneider I, Grau GE, Hollingdale MR, Ballou WR, Gordon DM. Humoral immune responses in volunteers immunized with irradiated Plasmodium falciparum sporozoites. Am J Trop Med Hyg. 1993 Aug; 49(2):166-73. PMID: 8357078.
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    187. Mazier D, Rénia L, Pied S, Nussler A, Marussig M, Landau I, Miltgen F, Grillot D, Del Giudice G, Grau G, et al. Hepatic stages of malaria: specific and non-specific factors inhibiting the development. Parassitologia. 1993 Jul; 35 Suppl:59-63. PMID: 8233615.
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    188. Parida SK, Grau GE. Role of TNF in immunopathology of leprosy. Res Immunol. 1993 Jun; 144(5):376-84. PMID: 8278661.
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    189. Chang HR, Vesin C, Grau GE, Pointaire P, Arsenijevic D, Strath M, Pechère JC, Piguet PF. Respective role of polymorphonuclear leukocytes and their integrins (CD-11/18) in the local or systemic toxicity of lipopolysaccharide. J Leukoc Biol. 1993 Jun; 53(6):636-9. PMID: 8315347.
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    190. Grau GE, Lou J. TNF in vascular pathology: the importance of platelet-endothelium interactions. Res Immunol. 1993 Jun; 144(5):355-63. PMID: 8278658.
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    191. Porta J, Carota A, Pizzolato GP, Wildi E, Widmer MC, Margairaz C, Grau GE. Immunopathological changes in human cerebral malaria. Clin Neuropathol. 1993 May-Jun; 12(3):142-6. PMID: 8100753.
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    192. Kremsner PG, Nüssler A, Neifer S, Chaves MF, Bienzle U, Senaldi G, Grau GE. Malaria antigen and cytokine-induced production of reactive nitrogen intermediates by murine macrophages: no relevance to the development of experimental cerebral malaria. Immunology. 1993 Feb; 78(2):286-90. PMID: 8473017; PMCID: PMC1421792.
    193. Piguet PF, Rosen H, Vesin C, Grau GE. Effective treatment of the pulmonary fibrosis elicited in mice by bleomycin or silica with anti-CD-11 antibodies. Am Rev Respir Dis. 1993 Feb; 147(2):435-41. PMID: 7679265.
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    194. Kwiatkowski D, Molyneux ME, Stephens S, Curtis N, Klein N, Pointaire P, Smit M, Allan R, Brewster DR, Grau GE, et al. Anti-TNF therapy inhibits fever in cerebral malaria. Q J Med. 1993 Feb; 86(2):91-8. PMID: 8329024.
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    195. Grau GE, Lambert PH, Vassalli P, Piguet PF. Tumor necrosis factor/cachectin as an effector of T cell-dependent immunopathology. Int Rev Exp Pathol. 1993; 34 Pt B:159-71. PMID: 8458711.
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    196. Motard A, Landau I, Nussler A, Grau G, Baccam D, Mazier D, Targett GA. The role of reactive nitrogen intermediates in modulation of gametocyte infectivity of rodent malaria parasites. Parasite Immunol. 1993 Jan; 15(1):21-6. PMID: 8433851.
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    197. de Kossodo S, Grau GE. Role of cytokines and adhesion molecules in malaria immunopathology. Stem Cells. 1993 Jan; 11(1):41-8. PMID: 8457780.
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    198. Piguet PF, Vesin C, Grau GE, Thompson RC. Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica. Cytokine. 1993 Jan; 5(1):57-61. PMID: 7683505.
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    199. Loutan L, Plancherel C, Soulier-Lauper M, Pascual M, Subilia L, Chevrolet JC, Unger PF, Grau GE. Serum TNF in patients with severe malaria treated by exchange transfusion. Trop Med Parasitol. 1992 Dec; 43(4):285-6. PMID: 1293736.
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    200. Piguet PF, Grau GE, Vesin C, Loetscher H, Gentz R, Lesslauer W. Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology. 1992 Dec; 77(4):510-4. PMID: 1337334; PMCID: PMC1421669.
    201. Desmoulière A, Rubbia-Brandt L, Grau G, Gabbiani G. Heparin induces alpha-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts. Lab Invest. 1992 Dec; 67(6):716-26. PMID: 1460862.
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    202. de Kossodo S, Grau GE, Daneva T, Pointaire P, Fossati L, Ody C, Zapf J, Piguet PF, Gaillard RC, Vassalli P. Tumor necrosis factor alpha is involved in mouse growth and lymphoid tissue development. J Exp Med. 1992 Nov 01; 176(5):1259-64. PMID: 1402671; PMCID: PMC2119431.
    203. Chofflon M, Juillard C, Juillard P, Gauthier G, Grau GE. Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis. Eur Cytokine Netw. 1992 Nov-Dec; 3(6):523-31. PMID: 1296800.
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    204. Gascon MP, Porchet HC, Le Cotonnec JY, Ythier A, Wallach D, Piguet PF, Grau GE. Pharmacokinetics and tissue distribution of human urinary tumor necrosis factor binding protein in mice. Drug Metab Dispos. 1992 Jul-Aug; 20(4):592-5. PMID: 1356740.
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    205. Vaudaux P, Grau GE, Huggler E, Schumacher-Perdreau F, Fiedler F, Waldvogel FA, Lew DP. Contribution of tumor necrosis factor to host defense against staphylococci in a guinea pig model of foreign body infections. J Infect Dis. 1992 Jul; 166(1):58-64. PMID: 1607709.
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    206. Karunaweera ND, Carter R, Grau GE, Kwiatkowski D, Del Giudice G, Mendis KN. Tumour necrosis factor-dependent parasite-killing effects during paroxysms in non-immune Plasmodium vivax malaria patients. Clin Exp Immunol. 1992 Jun; 88(3):499-505. PMID: 1351432; PMCID: PMC1554505.
    207. Suter PM, Suter S, Girardin E, Roux-Lombard P, Grau GE, Dayer JM. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am Rev Respir Dis. 1992 May; 145(5):1016-22. PMID: 1586041.
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    208. Girardin E, Roux-Lombard P, Grau GE, Suter P, Gallati H, Dayer JM. Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group. Immunology. 1992 May; 76(1):20-3. PMID: 1321092; PMCID: PMC1421754.
    209. Karunaweera ND, Grau GE, Gamage P, Carter R, Mendis KN. Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3200-3. PMID: 1565611; PMCID: PMC48833.
    210. Parida SK, Grau GE, Zaheer SA, Mukherjee R. Serum tumor necrosis factor and interleukin 1 in leprosy and during lepra reactions. Clin Immunol Immunopathol. 1992 Apr; 63(1):23-7. PMID: 1591878.
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    211. Tabone MD, Muanza K, Lyagoubi M, Jardel C, Pied S, Amedee-Manesme O, Grau GE, Mazier D. The role of interleukin-6 in vitamin A deficiency during Plasmodium falciparum malaria and possible consequences for vitamin A supplementation. Immunology. 1992 Mar; 75(3):553-4. PMID: 1572702; PMCID: PMC1384755.
    212. Grau GE. Essential role of tumor necrosis factor and other cytokines in the pathogenesis of cerebral malaria: experimental and clinical studies. Verh K Acad Geneeskd Belg. 1992; 54(2):155-75. PMID: 1357836.
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    213. Grau GE, Piguet PF, Lambert PH. Immunopathology of malaria: role of cytokine production and adhesion molecules. Mem Inst Oswaldo Cruz. 1992; 87 Suppl 5:95-100. PMID: 1342724.
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    214. Ferran C, Dy M, Sheehan K, Merite S, Schreiber R, Landais P, Grau G, Bluestone J, Bach JF, Chatenoud L. Inter-mouse strain differences in the in vivo anti-CD3 induced cytokine release. Clin Exp Immunol. 1991 Dec; 86(3):537-43. PMID: 1721015; PMCID: PMC1554204.
    215. Lesslauer W, Tabuchi H, Gentz R, Brockhaus M, Schlaeger EJ, Grau G, Piguet PF, Pointaire P, Vassalli P, Loetscher H. Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur J Immunol. 1991 Nov; 21(11):2883-6. PMID: 1657617.
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    216. Ferran C, Dy M, Sheehan K, Schreiber R, Grau G, Bluestone J, Bach JF, Chatenoud L. Cascade modulation by anti-tumor necrosis factor monoclonal antibody of interferon-gamma, interleukin 3 and interleukin 6 release after triggering of the CD3/T cell receptor activation pathway. Eur J Immunol. 1991 Oct; 21(10):2349-53. PMID: 1833202.
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    217. Grau GE, Pointaire P, Piguet PF, Vesin C, Rosen H, Stamenkovic I, Takei F, Vassalli P. Late administration of monoclonal antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria. Eur J Immunol. 1991 Sep; 21(9):2265-7. PMID: 1679717.
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    218. Grau GE, Modlin RL. Immune mechanisms in bacterial and parasitic diseases: protective immunity versus pathology. Curr Opin Immunol. 1991 Aug; 3(4):480-5. PMID: 1684508.
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    219. Grau GE, Vesin C, De Groote D, Delacroix D, Gysler C, Piguet PF, Lambert PH. Prevention of human TNF-induced cutaneous Shwartzmann reaction and acute mortality in mice treated with anti-human TNF monoclonal antibodies. Clin Exp Immunol. 1991 Jun; 84(3):411-4. PMID: 2044219; PMCID: PMC1535417.
    220. Molyneux ME, Taylor TE, Wirima JJ, Grau GE. Tumour necrosis factor, interleukin-6, and malaria. Lancet. 1991 May 04; 337(8749):1098. PMID: 1673519.
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    221. Sarno EN, Grau GE, Vieira LM, Nery JA. Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states. Clin Exp Immunol. 1991 Apr; 84(1):103-8. PMID: 2015700; PMCID: PMC1535359.
    222. Nussler A, Pied S, Goma J, Rénia L, Miltgen F, Grau GE, Mazier D. TNF inhibits malaria hepatic stages in vitro via synthesis of IL-6. Int Immunol. 1991 Apr; 3(4):317-21. PMID: 1878339.
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    223. Naotunne TS, Karunaweera ND, Del Giudice G, Kularatne MU, Grau GE, Carter R, Mendis KN. Cytokines kill malaria parasites during infection crisis: extracellular complementary factors are essential. J Exp Med. 1991 Mar 01; 173(3):523-9. PMID: 1900073; PMCID: PMC2118826.
    224. Piguet PF, Grau GE, Hauser C, Vassalli P. Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions. J Exp Med. 1991 Mar 01; 173(3):673-9. PMID: 1900080; PMCID: PMC2118812.
    225. Shaffer N, Grau GE, Hedberg K, Davachi F, Lyamba B, Hightower AW, Breman JG, Phuc ND. Tumor necrosis factor and severe malaria. J Infect Dis. 1991 Jan; 163(1):96-101. PMID: 1984482.
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    226. Chofflon M, Juillard C, Gauthier G, Grau GE. Correlation between in vitro cytokine production and clinical evolution of multiple sclerosis patients. Schweiz Arch Neurol Psychiatr (1985). 1991; 142(2):107-12. PMID: 1710376.
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    227. Grau GE, Frei K, Piguet PF, Fontana A, Heremans H, Billiau A, Vassalli P, Lambert PH. Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia. J Exp Med. 1990 Nov 01; 172(5):1505-8. PMID: 2121890; PMCID: PMC2188677.
    228. Grau GE. Implications of cytokines in immunopathology: experimental and clinical data. Eur Cytokine Netw. 1990 Oct-Nov; 1(4):203-10. PMID: 2104242.
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    229. Grau GE, Bieler G, Pointaire P, De Kossodo S, Tacchini-Cotier F, Vassalli P, Piguet PF, Lambert PH. Significance of cytokine production and adhesion molecules in malarial immunopathology. Immunol Lett. 1990 Aug; 25(1-3):189-94. PMID: 2283148.
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    230. Mendis KN, Naotunne TD, Karunaweera ND, Del Giudice G, Grau GE, Carter R. Anti-parasite effects of cytokines in malaria. Immunol Lett. 1990 Aug; 25(1-3):217-20. PMID: 2126526.
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    231. Girardin EP, Berner ME, Grau GE, Suter S, Lacourt G, Paunier L. Serum tumour necrosis factor in newborns at risk for infections. Eur J Pediatr. 1990 Jun; 149(9):645-7. PMID: 2373118.
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    232. Calandra T, Baumgartner JD, Grau GE, Wu MM, Lambert PH, Schellekens J, Verhoef J, Glauser MP. Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock. Swiss-Dutch J5 Immunoglobulin Study Group. J Infect Dis. 1990 May; 161(5):982-7. PMID: 2109023.
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    233. Piguet PF, Collart MA, Grau GE, Sappino AP, Vassalli P. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature. 1990 Mar 15; 344(6263):245-7. PMID: 2156165.
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    234. Ferran C, Sheehan K, Dy M, Schreiber R, Merite S, Landais P, Noel LH, Grau G, Bluestone J, Bach JF, et al. Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation. Eur J Immunol. 1990 Mar; 20(3):509-15. PMID: 2138557.
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    235. Baumgartner JD, Heumann D, Gerain J, Weinbreck P, Grau GE, Glauser MP. Association between protective efficacy of anti-lipopolysaccharide (LPS) antibodies and suppression of LPS-induced tumor necrosis factor alpha and interleukin 6. Comparison of O side chain-specific antibodies with core LPS antibodies. J Exp Med. 1990 Mar 01; 171(3):889-96. PMID: 2307935; PMCID: PMC2187790.
    236. Mazier D, Goma J, Pied S, Renia L, Nussler A, Miltgen F, Mattei D, Grau G. Hepatic phase of malaria: a crucial role as "go-between" with other stages. Bull World Health Organ. 1990; 68 Suppl:126-31. PMID: 2151269; PMCID: PMC2393019.
    237. Chizzolini C, Grau GE, Geinoz A, Schrijvers D. T lymphocyte interferon-gamma production induced by Plasmodium falciparum antigen is high in recently infected non-immune and low in immune subjects. Clin Exp Immunol. 1990 Jan; 79(1):95-9. PMID: 1967995; PMCID: PMC1534724.
    238. Grau GE, Lambert PH. Retroviral antigen expression on megakaryocytes and platelets: possible implications in the pathogenesis of thrombocytopenia. Prog Clin Biol Res. 1990; 356:275-86. PMID: 2217444.
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    239. Piguet PF, Grau GE, Vassalli P. Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis. Am J Pathol. 1990 Jan; 136(1):103-10. PMID: 1688687; PMCID: PMC1877459.
    240. Chang HR, Grau GE, Pechère JC. Role of TNF and IL-1 in infections with Toxoplasma gondii. Immunology. 1990 Jan; 69(1):33-7. PMID: 2107144; PMCID: PMC1385716.
    241. Grau GE, Lambert PH, Vassalli P, Piguet PF. [Tumor necrosis factor (TNF) and pathology; its relationships with other cytokines]. Schweiz Med Wochenschr. 1989 Dec 09; 119(49):1756-61. PMID: 2482541.
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    242. Grau GE, Piguet PF, Vassalli P, Lambert PH. Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol Rev. 1989 Dec; 112:49-70. PMID: 2575074.
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    243. Suter S, Schaad UB, Roux-Lombard P, Girardin E, Grau G, Dayer JM. Relation between tumor necrosis factor-alpha and granulocyte elastase-alpha 1-proteinase inhibitor complexes in the plasma of patients with cystic fibrosis. Am Rev Respir Dis. 1989 Dec; 140(6):1640-4. PMID: 2604293.
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    244. Beylot M, Guiraud M, Grau G, Bouletreau P. Regulation of ketone body flux in septic patients. Am J Physiol. 1989 Nov; 257(5 Pt 1):E665-74. PMID: 2596597.
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    245. Piguet PF, Collart MA, Grau GE, Kapanci Y, Vassalli P. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med. 1989 Sep 01; 170(3):655-63. PMID: 2475571; PMCID: PMC2189418.
    246. Merino J, Qin HY, Schurmans S, Gretener D, Grau GE, Lambert PH. Thrombocytopenia associated with the induction of neonatal tolerance to alloantigens: immunopathogenic mechanisms. Eur J Immunol. 1989 Sep; 19(9):1693-9. PMID: 2792184.
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    247. Piguet PF, Grau GE, Collart MA, Vassalli P, Kapanci Y. Pneumopathies of the graft-versus-host reaction. Alveolitis associated with an increased level of tumor necrosis factor mRNA and chronic interstitial pneumonitis. Lab Invest. 1989 Jul; 61(1):37-45. PMID: 2747216.
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    248. Grau GE, Heremans H, Piguet PF, Pointaire P, Lambert PH, Billiau A, Vassalli P. Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci U S A. 1989 Jul; 86(14):5572-4. PMID: 2501793; PMCID: PMC297664.
    249. Grau GE, Taylor TE, Molyneux ME, Wirima JJ, Vassalli P, Hommel M, Lambert PH. Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med. 1989 Jun 15; 320(24):1586-91. PMID: 2657427.
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    250. Girardin E, Berner M, Grau GE, Dayer JM, Roux-Lombard P, Suter S. Tumour necrosis factor in neonatal listeriosis: a case report. Eur J Pediatr. 1989 Jun; 148(7):644-5. PMID: 2744036.
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    251. Del Giudice G, Cheng Q, Mazier D, Meuwissen JH, Grau GE, Corradin G, Pessi A, Verdini AS, Lambert PH. Primary and secondary responses to (NANP) peptides by Plasmodium falciparum sporozoites in various strains of mice. Scand J Immunol. 1989 May; 29(5):555-62. PMID: 2471257.
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    252. Kindler V, Sappino AP, Grau GE, Piguet PF, Vassalli P. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell. 1989 Mar 10; 56(5):731-40. PMID: 2647299.
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    253. Heremans H, Dillen C, Dijkmans R, Grau G, Billiau A. The role of cytokines in various animal models of inflammation. Lymphokine Res. 1989; 8(3):329-33. PMID: 2506397.
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    254. Grau GE, Piguet PF, Vassalli P, Lambert PH. Involvement of tumour necrosis factor and other cytokines in immune-mediated vascular pathology. Int Arch Allergy Appl Immunol. 1989; 88(1-2):34-9. PMID: 2651318.
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    255. Grau GE, Piguet PF, Gretener D, Vesin C, Lambert PH. Immunopathology of thrombocytopenia in experimental malaria. Immunology. 1988 Dec; 65(4):501-6. PMID: 3065215; PMCID: PMC1385556.
    256. Grau GE, Kindler V, Piguet PF, Lambert PH, Vassalli P. Prevention of experimental cerebral malaria by anticytokine antibodies. Interleukin 3 and granulocyte macrophage colony-stimulating factor are intermediates in increased tumor necrosis factor production and macrophage accumulation. J Exp Med. 1988 Oct 01; 168(4):1499-504. PMID: 3049913; PMCID: PMC2189068.
    257. Girardin E, Grau GE, Dayer JM, Roux-Lombard P, Lambert PH. Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. N Engl J Med. 1988 Aug 18; 319(7):397-400. PMID: 3135497.
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    258. Del Giudice G, Grau GE, Lambert PH. Host responsiveness to malaria epitopes and immunopathology. Prog Allergy. 1988; 41:288-330. PMID: 2457218.
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    259. Piguet PF, Grau GE, Allet B, Vassalli P. Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease. J Exp Med. 1987 Nov 01; 166(5):1280-9. PMID: 3316469; PMCID: PMC2189667.
    260. Grau GE, Fajardo LF, Piguet PF, Allet B, Lambert PH, Vassalli P. Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science. 1987 Sep 04; 237(4819):1210-2. PMID: 3306918.
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    261. Grau GE, Gretener D, Lambert PH. Prevention of murine cerebral malaria by low-dose cyclosporin A. Immunology. 1987 Aug; 61(4):521-5. PMID: 3327806; PMCID: PMC1453449.
    262. Grau GE, Del Giudice G, Lambert PH. Host immune response and pathological expression in malaria: possible implications for malaria vaccines. Parasitology. 1987; 94 Suppl:S123-37. PMID: 2438630.
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    263. Grau GE, Piguet PF, Engers HD, Louis JA, Vassalli P, Lambert PH. L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol. 1986 Oct 01; 137(7):2348-54. PMID: 3093572.
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    264. Piguet PF, Grau G, Irle C, Vassalli P. Administration of recombinant interleukin 2 to mice enhances production of hemopoietic and natural killer cells. Eur J Immunol. 1986 Oct; 16(10):1257-61. PMID: 3490387.
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    265. Grau GE, Morrow D, Izui S, Lambert PH. Pathogenesis of the delayed phase of Rauscher virus-induced thrombocytopenia. J Immunol. 1986 Jan; 136(2):686-91. PMID: 3455704.
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    266. Grau GE, Puthavathana P, Izui S, Lambert PH. Induction of acute thrombocytopenia and infection of megakaryocytes by Rauscher murine leukemia virus reflect the genetic susceptibility to leukemogenesis. J Exp Med. 1983 Mar 01; 157(3):1028-39. PMID: 6833948; PMCID: PMC2186971.
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