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Professor Ruth Nussenzweig

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Huang J, Li X, Coelho-dos-Reis JG, Zhang M, Mitchell R, Nogueira RT, Tsao T, Noe AR, Ayala R, Sahi V, Gutierrez GM, Nussenzweig V, Wilson JM, Nardin EH, Nussenzweig RS, Tsuji M. Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria. J Immunol Methods. 2015 Dec; 427:42-50. PMID: 26410104.
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    2. Teixeira LH, Tararam CA, Lasaro MO, Camacho AG, Ersching J, Leal MT, Herrera S, Bruna-Romero O, Soares IS, Nussenzweig RS, Ertl HC, Nussenzweig V, Rodrigues MM. Immunogenicity of a prime-boost vaccine containing the circumsporozoite proteins of Plasmodium vivax in rodents. Infect Immun. 2014 Feb; 82(2):793-807. PMID: 24478093; PMCID: PMC3911365.
    3. Mishra S, Nussenzweig RS, Nussenzweig V. Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity. J Immunol Methods. 2012 Mar 30; 377(1-2):47-52. PMID: 22306356; PMCID: PMC3310221.
    4. Camacho AG, Teixeira LH, Bargieri DY, Boscardin SB, Soares IS, Nussenzweig RS, Nussenzweig V, Rodrigues MM. TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium. Mem Inst Oswaldo Cruz. 2011 Aug; 106 Suppl 1:167-71. PMID: 21881771.
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    5. Mishra S, Rai U, Shiratsuchi T, Li X, Vanloubbeeck Y, Cohen J, Nussenzweig RS, Winzeler EA, Tsuji M, Nussenzweig V. Identification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites. Vaccine. 2011 Oct 06; 29(43):7335-42. PMID: 21807053; PMCID: PMC3603353.
    6. Nussenzweig RS, Krettli AU. Breakthroughs towards a malaria vaccine. Hist Cienc Saude Manguinhos. 2011 Jun 01; 18(2):559-64. PMID: 21779699.
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    7. Zhang M, Fennell C, Ranford-Cartwright L, Sakthivel R, Gueirard P, Meister S, Caspi A, Doerig C, Nussenzweig RS, Tuteja R, Sullivan WJ, Roos DS, Fontoura BM, Ménard R, Winzeler EA, Nussenzweig V. The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands. J Exp Med. 2010 Jul 05; 207(7):1465-74. PMID: 20584882; PMCID: PMC2901070.
    8. Stoyanov CT, Boscardin SB, Deroubaix S, Barba-Spaeth G, Franco D, Nussenzweig RS, Nussenzweig M, Rice CM. Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii. Vaccine. 2010 Jun 23; 28(29):4644-52. PMID: 20451637; PMCID: PMC2935264.
    9. Cohen J, Nussenzweig V, Nussenzweig R, Vekemans J, Leach A. From the circumsporozoite protein to the RTS, S/AS candidate vaccine. Hum Vaccin. 2010 Jan; 6(1):90-6. PMID: 19806009.
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    10. Kubler-Kielb J, Majadly F, Biesova Z, Mocca CP, Guo C, Nussenzweig R, Nussenzweig V, Mishra S, Wu Y, Miller LH, Keith JM, Liu TY, Robbins JB, Schneerson R. A bicomponent Plasmodium falciparum investigational vaccine composed of protein-peptide conjugates. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1172-7. PMID: 20080619; PMCID: PMC2824317.
    11. Kumar KA, Sano G, Boscardin S, Nussenzweig RS, Nussenzweig MC, Zavala F, Nussenzweig V. The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites. Nature. 2006 Dec 14; 444(7121):937-40. PMID: 17151604.
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    12. Boscardin SB, Hafalla JC, Masilamani RF, Kamphorst AO, Zebroski HA, Rai U, Morrot A, Zavala F, Steinman RM, Nussenzweig RS, Nussenzweig MC. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med. 2006 Mar 20; 203(3):599-606. PMID: 16505139; PMCID: PMC2118236.
    13. Oliveira GA, Wetzel K, Calvo-Calle JM, Nussenzweig R, Schmidt A, Birkett A, Dubovsky F, Tierney E, Gleiter CH, Boehmer G, Luty AJ, Ramharter M, Thornton GB, Kremsner PG, Nardin EH. Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial. Infect Immun. 2005 Jun; 73(6):3587-97. PMID: 15908388; PMCID: PMC1111818.
    14. Tao D, Barba-Spaeth G, Rai U, Nussenzweig V, Rice CM, Nussenzweig RS. Yellow fever 17D as a vaccine vector for microbial CTL epitopes: protection in a rodent malaria model. J Exp Med. 2005 Jan 17; 201(2):201-9. PMID: 15657290; PMCID: PMC2212788.
    15. González-Aseguinolaza G, Nakaya Y, Molano A, Dy E, Esteban M, Rodríguez D, Rodríguez JR, Palese P, García-Sastre A, Nussenzweig RS. Induction of protective immunity against malaria by priming-boosting immunization with recombinant cold-adapted influenza and modified vaccinia Ankara viruses expressing a CD8+-T-cell epitope derived from the circumsporozoite protein of Plasmodium yoelii. J Virol. 2003 Nov; 77(21):11859-66. PMID: 14557672; PMCID: PMC229373.
    16. Birkett A, Lyons K, Schmidt A, Boyd D, Oliveira GA, Siddique A, Nussenzweig R, Calvo-Calle JM, Nardin E. A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts. Infect Immun. 2002 Dec; 70(12):6860-70. PMID: 12438363; PMCID: PMC133050.
    17. Thathy V, Fujioka H, Gantt S, Nussenzweig R, Nussenzweig V, Ménard R. Levels of circumsporozoite protein in the Plasmodium oocyst determine sporozoite morphology. EMBO J. 2002 Apr 02; 21(7):1586-96. PMID: 11927543; PMCID: PMC125957.
    18. Kublin JG, Lowitt MH, Hamilton RG, Oliveira GA, Nardin EH, Nussenzweig RS, Schmeckpeper BJ, Diggs CL, Bodison SA, Edelman R. Delayed-type hypersensitivity in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites. Vaccine. 2002 Mar 15; 20(13-14):1853-61. PMID: 11906775.
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    19. Bonaldo MC, Garratt RC, Caufour PS, Freire MS, Rodrigues MM, Nussenzweig RS, Galler R. Surface expression of an immunodominant malaria protein B cell epitope by yellow fever virus. J Mol Biol. 2002 Jan 25; 315(4):873-85. PMID: 11812154.
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    20. Bruña-Romero O, González-Aseguinolaza G, Hafalla JC, Tsuji M, Nussenzweig RS. Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11491-6. PMID: 11553779; PMCID: PMC58757.
    21. Mota MM, Thathy V, Nussenzweig RS, Nussenzweig V. Gene targeting in the rodent malaria parasite Plasmodium yoelii. Mol Biochem Parasitol. 2001 Apr 06; 113(2):271-8. PMID: 11295181.
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    22. Zavala F, Rodrigues M, Rodriguez D, Rodriguez JR, Nussenzweig RS, Esteban M. A striking property of recombinant poxviruses: efficient inducers of in vivo expansion of primed CD8(+) T cells. Virology. 2001 Feb 15; 280(2):155-9. PMID: 11162829.
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    23. Mota MM, Pradel G, Vanderberg JP, Hafalla JC, Frevert U, Nussenzweig RS, Nussenzweig V, Rodríguez A. Migration of Plasmodium sporozoites through cells before infection. Science. 2001 Jan 05; 291(5501):141-4. PMID: 11141568.
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    24. Nardin EH, Calvo-Calle JM, Oliveira GA, Nussenzweig RS, Schneider M, Tiercy JM, Loutan L, Hochstrasser D, Rose K. A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types. J Immunol. 2001 Jan 01; 166(1):481-9. PMID: 11123327.
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    25. Nardin EH, Oliveira GA, Calvo-Calle JM, Castro ZR, Nussenzweig RS, Schmeckpeper B, Hall BF, Diggs C, Bodison S, Edelman R. Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes. J Infect Dis. 2000 Nov; 182(5):1486-96. PMID: 11023472.
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    26. Oliveira-Ferreira J, Miyahira Y, Layton GT, Savage N, Esteban M, Rodriguez D, Rodriguez JR, Nussenzweig RS, Zavala F, Myahira Y. Immunogenicity of Ty-VLP bearing a CD8(+) T cell epitope of the CS protein of P. yoelii: enhanced memory response by boosting with recombinant vaccinia virus. Vaccine. 2000 Mar 06; 18(17):1863-9. PMID: 10699335.
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    27. Rodrigues EG, Claassen J, Lee S, Wilson JM, Nussenzweig RS, Tsuji M. Interferon-gamma-independent CD8+ T cell-mediated protective anti-malaria immunity elicited by recombinant adenovirus. Parasite Immunol. 2000 Mar; 22(3):157-60. PMID: 10672197.
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    28. Nardin E, Zavala F, Nussenzweig V, Nussenzweig RS. Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials. Parassitologia. 1999 Sep; 41(1-3):397-402. PMID: 10697892.
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    29. Moreno CA, Rodriguez R, Oliveira GA, Ferreira V, Nussenzweig RS, Moya Castro ZR, Calvo-Calle JM, Nardin E. Preclinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice. Vaccine. 1999 Aug 20; 18(1-2):89-99. PMID: 10501239.
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    30. Nunes A, Thathy V, Bruderer T, Sultan AA, Nussenzweig RS, Ménard R. Subtle mutagenesis by ends-in recombination in malaria parasites. Mol Cell Biol. 1999 Apr; 19(4):2895-902. PMID: 10082556; PMCID: PMC84083.
    31. Luty AJ, Lell B, Schmidt-Ott R, Lehman LG, Luckner D, Greve B, Matousek P, Herbich K, Schmid D, Migot-Nabias F, Deloron P, Nussenzweig RS, Kremsner PG. Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children. J Infect Dis. 1999 Apr; 179(4):980-8. PMID: 10068595.
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    32. Rodrigues EG, Zavala F, Nussenzweig RS, Wilson JM, Tsuji M. Efficient induction of protective anti-malaria immunity by recombinant adenovirus. Vaccine. 1998 Nov; 16(19):1812-7. PMID: 9795385.
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    33. Tsuji M, Bergmann CC, Takita-Sonoda Y, Murata K, Rodrigues EG, Nussenzweig RS, Zavala F. Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice. J Virol. 1998 Aug; 72(8):6907-10. PMID: 9658144; PMCID: PMC109904.
    34. Nardin EH, Calvo-Calle JM, Oliveira GA, Clavijo P, Nussenzweig R, Simon R, Zeng W, Rose K. Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein. Vaccine. 1998 Apr; 16(6):590-600. PMID: 9569470.
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    35. Miyahira Y, García-Sastre A, Rodriguez D, Rodriguez JR, Murata K, Tsuji M, Palese P, Esteban M, Zavala F, Nussenzweig RS. Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8+ responses in mice. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3954-9. PMID: 9520474; PMCID: PMC19944.
    36. Sultan AA, Thathy V, Frevert U, Robson KJ, Crisanti A, Nussenzweig V, Nussenzweig RS, Ménard R. TRAP is necessary for gliding motility and infectivity of plasmodium sporozoites. Cell. 1997 Aug 08; 90(3):511-22. PMID: 9267031.
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    37. Palese P, Zavala F, Muster T, Nussenzweig RS, García-Sastre A. Development of novel influenza virus vaccines and vectors. J Infect Dis. 1997 Aug; 176 Suppl 1:S45-9. PMID: 9240694.
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    38. Ménard R, Sultan AA, Cortes C, Altszuler R, van Dijk MR, Janse CJ, Waters AP, Nussenzweig RS, Nussenzweig V. Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes. Nature. 1997 Jan 23; 385(6614):336-40. PMID: 9002517.
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    39. Nussenzweig RS, Zavala F. A malaria vaccine based on a sporozoite antigen. N Engl J Med. 1997 Jan 09; 336(2):128-30. PMID: 8988893.
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    40. Takita-Sonoda Y, Tsuji M, Kamboj K, Nussenzweig RS, Clavijo P, Zavala F. Plasmodium yoelii: peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein. Exp Parasitol. 1996 Nov; 84(2):223-30. PMID: 8932772.
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    41. Murata K, García-Sastre A, Tsuji M, Rodrigues M, Rodriguez D, Rodriguez JR, Nussenzweig RS, Palese P, Esteban M, Zavala F. Characterization of in vivo primary and secondary CD8+ T cell responses induced by recombinant influenza and vaccinia viruses. Cell Immunol. 1996 Oct 10; 173(1):96-107. PMID: 8871605.
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    42. Tsuji M, Eyster CL, O'Brien RL, Born WK, Bapna M, Reichel M, Nussenzweig RS, Zavala F. Phenotypic and functional properties of murine gamma delta T cell clones derived from malaria immunized, alpha beta T cell-deficient mice. Int Immunol. 1996 Mar; 8(3):359-66. PMID: 8728988.
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    43. Marrelli MT, Nussenzweig RS, Collins WE, Kloetzel JK. Detection of anti-Plasmodium falciparum antibodies directed against a repetitive peptide of the gametocyte antigen Pfs2400 in malaria patients in Brazil. Ann Trop Med Parasitol. 1995 Dec; 89(6):593-99. PMID: 8745934.
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    44. Tsuji M, Miyahira Y, Nussenzweig RS, Aguet M, Reichel M, Zavala F. Development of antimalaria immunity in mice lacking IFN-gamma receptor. J Immunol. 1995 May 15; 154(10):5338-44. PMID: 7537305.
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    45. Nardin EH, Oliveira GA, Calvo-Calle JM, Nussenzweig RS. The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases. Adv Immunol. 1995; 60:105-49. PMID: 8607369.
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    46. Rodrigues M, Li S, Murata K, Rodriguez D, Rodriguez JR, Bacik I, Bennink JR, Yewdell JW, Garcia-Sastre A, Nussenzweig RS, et al. Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity. J Immunol. 1994 Nov 15; 153(10):4636-48. PMID: 7525709.
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    47. Nussenzweig RS, Long CA. Malaria vaccines: multiple targets. Science. 1994 Sep 02; 265(5177):1381-3. PMID: 8073276.
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    48. de Oliveira GA, Clavijo P, Nussenzweig RS, Nardin EH. Immunogenicity of an alum-adsorbed synthetic multiple-antigen peptide based on B- and T-cell epitopes of the Plasmodium falciparum CS protein: possible vaccine application. Vaccine. 1994 Aug; 12(11):1012-7. PMID: 7526570.
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    49. Tsuji M, Mombaerts P, Lefrancois L, Nussenzweig RS, Zavala F, Tonegawa S. Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):345-9. PMID: 8278391; PMCID: PMC42944.
    50. Tsuji M, Mattei D, Nussenzweig RS, Eichinger D, Zavala F. Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites. Parasitol Res. 1994; 80(1):16-21. PMID: 8153120.
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    51. Rodrigues M, Nussenzweig RS, Zavala F. The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria. Immunology. 1993 Sep; 80(1):1-5. PMID: 7902331; PMCID: PMC1422124.
    52. Branquinho MS, Lagos CB, Rocha RM, Natal D, Barata JM, Cochrane AH, Nardin E, Nussenzweig RS, Kloetzel JK. Anophelines in the state of Acre, Brazil, infected with Plasmodium falciparum, P. vivax, the variant P. vivax VK247 and P. malariae. Trans R Soc Trop Med Hyg. 1993 Jul-Aug; 87(4):391-4. PMID: 8249059.
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    53. Li S, Rodrigues M, Rodriguez D, Rodriguez JR, Esteban M, Palese P, Nussenzweig RS, Zavala F. Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5214-8. PMID: 7685119; PMCID: PMC46686.
    54. Calvo-Calle JM, de Oliveira GA, Clavijo P, Maracic M, Tam JP, Lu YA, Nardin EH, Nussenzweig RS, Cochrane AH. Immunogenicity of multiple antigen peptides containing B and non-repeat T cell epitopes of the circumsporozoite protein of Plasmodium falciparum. J Immunol. 1993 Feb 15; 150(4):1403-12. PMID: 7679427.
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    55. Feng Z, Hoffmann RN, Nussenzweig RS, Tsuji M, Fujioka H, Aikawa M, Lensen TH, Ponnudurai T, Pologe LG. Pfs2400 can mediate antibody-dependent malaria transmission inhibition and may be the Plasmodium falciparum 11.1 gene product. J Exp Med. 1993 Feb 01; 177(2):273-81. PMID: 8426106; PMCID: PMC2190917.
    56. Nardin EH, Nussenzweig RS. T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages. Annu Rev Immunol. 1993; 11:687-727. PMID: 8476576.
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    57. Subbarao SK, Vasantha K, Joshi H, Raghavendra K, Usha Devi C, Sathyanarayan TS, Cochrane AH, Nussenzweig RS, Sharma VP. Role of Anopheles culicifacies sibling species in malaria transmission in Madhya Pradesh state, India. Trans R Soc Trop Med Hyg. 1992 Nov-Dec; 86(6):613-4. PMID: 1287914.
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    58. Calle JM, Nardin EH, Clavijo P, Boudin C, Stüber D, Takacs B, Nussenzweig RS, Cochrane AH. Recognition of different domains of the Plasmodium falciparum CS protein by the sera of naturally infected individuals compared with those of sporozoite-immunized volunteers. J Immunol. 1992 Oct 15; 149(8):2695-701. PMID: 1401909.
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    59. Rodrigues M, Nussenzweig RS, Romero P, Zavala F. The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules. J Exp Med. 1992 Apr 01; 175(4):895-905. PMID: 1372647; PMCID: PMC2119175.
    60. Nardin E, Munesinghe YD, Moreno A, Clavijo P, Calle MC, Edelman R, Davis J, Herrington D, Nussenzweig RS. T cell responses to repeat and non-repeat regions of the circumsporozoite protein detected in volunteers immunized with Plasmodium falciparum sporozoites. Mem Inst Oswaldo Cruz. 1992; 87 Suppl 3:223-7. PMID: 1364202.
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    61. Kremsner PG, Neifer S, Zotter GM, Bienzle U, Rocha RM, Maracic M, Clavijo P, Nussenzweig RS, Cochrane AH. Prevalence and level of antibodies to the circumsporozoite proteins of human malaria parasites, including a variant of Plasmodium vivax, in the population of two epidemiologically distinct areas in the state of Acre, Brazil. Trans R Soc Trop Med Hyg. 1992 Jan-Feb; 86(1):23-7. PMID: 1373529.
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    62. Munesinghe DY, Clavijo P, Calle MC, Nussenzweig RS, Nardin E. Immunogenicity of multiple antigen peptides (MAP) containing T and B cell epitopes of the repeat region of the P. falciparum circumsporozoite protein. Eur J Immunol. 1991 Dec; 21(12):3015-20. PMID: 1721025.
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    63. Millet P, Collins WE, Broderson JR, Bathurst I, Nardin EH, Nussenzweig RS. Inhibitory activity against Plasmodium vivax sporozoites induced by plasma from Saimiri monkeys immunized with circumsporozoite recombinant proteins or irradiated sporozoites. Am J Trop Med Hyg. 1991 Jul; 45(1):44-8. PMID: 1907809.
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    64. Rodrigues MM, Cordey AS, Arreaza G, Corradin G, Romero P, Maryanski JL, Nussenzweig RS, Zavala F. CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. Int Immunol. 1991 Jun; 3(6):579-85. PMID: 1716146.
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    65. Hoffman SL, Nussenzweig V, Sadoff JC, Nussenzweig RS. Progress toward malaria preerythrocytic vaccines. Science. 1991 Apr 26; 252(5005):520-1. PMID: 2020852.
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    66. Nardin E, Clavijo P, Mons B, van Belkum A, Ponnudurai T, Nussenzweig RS. T cell epitopes of the circumsporozoite protein of Plasmodium vivax. Recognition by lymphocytes of a sporozoite-immunized chimpanzee. J Immunol. 1991 Mar 01; 146(5):1674-8. PMID: 1704402.
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    67. Collins WE, Nussenzweig RS, Ruebush TK, Bathurst IC, Nardin EH, Gibson HL, Campbell GH, Barr PJ, Broderson JR, Skinner JC, et al. Further studies on the immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax. Am J Trop Med Hyg. 1990 Dec; 43(6):576-83. PMID: 1702586.
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    68. Yoshida N, Di Santi SM, Dutra AP, Nussenzweig RS, Nussenzweig V, Enea V. Plasmodium falciparum: restricted polymorphism of T cell epitopes of the circumsporozoite protein in Brazil. Exp Parasitol. 1990 Nov; 71(4):386-92. PMID: 1699781.
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    69. Tsuji M, Romero P, Nussenzweig RS, Zavala F. CD4+ cytolytic T cell clone confers protection against murine malaria. J Exp Med. 1990 Nov 01; 172(5):1353-7. PMID: 2146361; PMCID: PMC2188671.
    70. Nussenzweig RS. Recombinant proteins and synthetic peptides as malaria vaccine candidates. Can J Microbiol. 1990 Nov; 36(11):817-20. PMID: 2279239.
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    71. Cochrane AH, Nardin EH, de Arruda M, Maracic M, Clavijo P, Collins WE, Nussenzweig RS. Widespread reactivity of human sera with a variant repeat of the circumsporozoite protein of Plasmodium vivax. Am J Trop Med Hyg. 1990 Nov; 43(5):446-51. PMID: 2122747.
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    72. Nussenzweig V, Nussenzweig RS. Progress toward a malaria vaccine. Hosp Pract (Off Ed). 1990 Sep 15; 25(9):45-52, 55-7. PMID: 2118918.
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    73. Romero P, Maryanski JL, Cordey AS, Corradin G, Nussenzweig RS, Zavala F. Isolation and characterization of protective cytolytic T cells in a rodent malaria model system. Immunol Lett. 1990 Aug; 25(1-3):27-31. PMID: 1704348.
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    74. Nussenzweig RS, Yoshida N. Variation of T cell epitopes of the Plasmodium falciparum CS protein: its occurrence, extent and relevance. Immunol Lett. 1990 Aug; 25(1-3):21-2. PMID: 1704346.
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    75. Tam JP, Clavijo P, Lu YA, Nussenzweig V, Nussenzweig R, Zavala F. Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. J Exp Med. 1990 Jan 01; 171(1):299-306. PMID: 1688609; PMCID: PMC2187660.
    76. Nardin EH, Nussenzweig RS, Altszuler R, Herrington D, Levine M, Murphy J, Davis J, Bathurst I, Barr P, Romero P, et al. Cellular and humoral immune responses to a recombinant P. falciparum CS protein in sporozoite-immunized rodents and human volunteers. Bull World Health Organ. 1990; 68 Suppl:85-7. PMID: 2094595; PMCID: PMC2393052.
    77. Cochrane AH, Uni S, Maracic M, di Giovanni L, Aikawa M, Nussenzweig RS. Presence of a circumsporozoite-like protein in micronemes of blood-stage merozoites of malaria parasites. Bull World Health Organ. 1990; 68 Suppl:181-3. PMID: 2094585; PMCID: PMC2393026.
    78. Herrington DA, Clyde DF, Davis JR, Baqar S, Murphy JR, Cortese JF, Bank RS, Nardin E, DiJohn D, Nussenzweig RS, et al. Human studies with synthetic peptide sporozoite vaccine (NANP)3-TT and immunization with irradiated sporozoites. Bull World Health Organ. 1990; 68 Suppl:33-7. PMID: 2094588; PMCID: PMC2393031.
    79. Cochrane AH, Uni S, Maracic M, Di Giovanni L, Aikawa M, Nussenzweig RS. A circumsporozoite-like protein is present in micronemes of mature blood stages of malaria parasites. Exp Parasitol. 1989 Nov; 69(4):351-6. PMID: 2478385.
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    80. de Arruda M, Nardin EH, Nussenzweig RS, Cochrane AH. Sero-epidemiological studies of malaria in Indian tribes and monkeys of the Amazon Basin of Brazil. Am J Trop Med Hyg. 1989 Oct; 41(4):379-85. PMID: 2508499.
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    81. Romero P, Maryanski JL, Corradin G, Nussenzweig RS, Nussenzweig V, Zavala F. Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature. 1989 Sep 28; 341(6240):323-6. PMID: 2477703.
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    82. Collins WE, Nussenzweig RS, Ballou WR, Ruebush TK, Nardin EH, Chulay JD, Majarian WR, Young JF, Wasserman GF, Bathurst I, et al. Immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax. Am J Trop Med Hyg. 1989 May; 40(5):455-64. PMID: 2658634.
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    181. Spitalny GL, Rivera-Ortiz CI, Nussenzweig RS. Plasmodium berghei: the spleen in sporozoite-induced immunity to mouse malaria. Exp Parasitol. 1976 Oct; 40(2):179-88. PMID: 786705.
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    182. Chen DH, Nussenzweig RS, Collins WE. Specificity of the circum-sporozoite precipitation antigen(s) of human and simian malarias. J Parasitol. 1976 Aug; 62(4):636-7. PMID: 60482.
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    183. Cochrane AH, Aikawa M, Jeng M, Nussenzweig RS. Antibody-induced ultrastructural changes of malarial sporozoites. J Immunol. 1976 Mar; 116(3):859-67. PMID: 815435.
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    184. Rivera-Ortiz CI, Nussenzweig R. Trichinella spiralis: anaphylactic antibody formation and susceptibility in strains of inbred mice. Exp Parasitol. 1976 Feb; 39(1):7-17. PMID: 1253885.
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    185. Krettli AU, Nussenzweig V, Nussenzweig RS. Complement alterations in rodent malaria. Am J Trop Med Hyg. 1976 Jan; 25(1):34-41. PMID: 816212.
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    186. Shapiro M, Espinal-Tejada C, Nussenzweig RS. Evaluation of a method for in vitro ookinete development of the rodent malarial parasite, Plasmodium berghei. J Parasitol. 1975 Dec; 61(6):1105-6. PMID: 1104798.
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    187. Hargreaves J, Yoeli M, Nussenzweig RS. Immunological studies in rodent malaria. I: Protective immunity induced in mice by mild strains of Plasmodium berghei yoelii against a virulent and fatal line of this plasmodium. Ann Trop Med Parasitol. 1975 Sep; 69(3):289-99. PMID: 1098589.
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    188. Nussenzweig RS, Chen D. [Various characteristics of the immune response to sporozoites of simian and human malaria]. Bol Oficina Sanit Panam. 1974 Dec; 77(6):469-77. PMID: 4280915.
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    189. Krettli AU, Nussenzweig R. Depletion of T and B lymphocytes during malarial infections. Cell Immunol. 1974 Sep; 13(3):440-6. PMID: 4548861.
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    190. Nussenzweig RS, Chen D. Some characteristics of the immune response to sporozoites of simian and human malaria. Bull Pan Am Health Organ. 1974; 8(3):198-204. PMID: 4138052.
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    191. Nussenzweig RS, Chen D. The antibody response to sporozoites of simian and human malaria parasites: its stage and species specificity and strain cross-reactivity. Bull World Health Organ. 1974; 50(3-4):293-7. PMID: 4548393; PMCID: PMC2481184.
    192. Krettli A, Chen DH, Nussenzweig RS. Immunogenicity and infectivity of sporozoites of mammalian malaria isolated by density-gradient centrifugation. J Protozool. 1973 Nov; 20(5):662-5. PMID: 4202832.
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    193. Nussenzweig RS, Montuori W, Spitalny GL, Chen D. [Antibodies against sporozoites of human and simian malaria produced in rats]. Bol Oficina Sanit Panam. 1973 Aug; 75(2):114-8. PMID: 4269913.
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    194. Spitalny GL, Nussenzweig RS. Plasmodium berghei: relationship between protective immunity and anti-sporozoite (CSP) antibody in mice. Exp Parasitol. 1973 Feb; 33(1):168-78. PMID: 4570978.
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    195. Nussenzweig RS, Montuori W, Spitalny GL, Chen D. Antibodies against sporozoites of human and simian malaria produced in rats. J Immunol. 1973 Feb; 110(2):600-1. PMID: 4405323.
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    196. Nussenzweig RS, Vanderberg J, Spitalny GL, Rivera CI, Orton C, Most H. Sporozoite-induced immunity in mammalian malaria. A review. Am J Trop Med Hyg. 1972 Sep; 21(5):722-8. PMID: 4561520.
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    197. Aikawa M, Nussenzweig R. Fine structure of Haemobartonella sp. in the squirrel monkey. J Parasitol. 1972 Jun; 58(3):628-30. PMID: 4625325.
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    198. Nussenzweig RS, Vanderberg JP, Sanabria Y, Most H. Plasmodium berghei: accelerated clearance of sporozoites from blood as part of immune-mechanism in mice. Exp Parasitol. 1972 Feb; 31(1):88-97. PMID: 5010609.
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    199. Jahiel RI, Vilcek J, Nussenzweig RS. Exogenous interferon protects mice against Plasmodium berghei malaria. Nature. 1970 Sep 26; 227(5265):1350-1. PMID: 5455140.
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    200. Jahiel RI, Nussenzweig RS, Vilcek J, Vanderberg J. Protective effect of interferon inducers on Plasmodium berghei malaria. Am J Trop Med Hyg. 1969 Nov; 18(6):823-35. PMID: 5389768.
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    201. Vanderberg J, Nussenzweig R, Most H. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. V. In vitro effects of immune serum on sporozoites. Mil Med. 1969 Sep; 134(10):1183-90. PMID: 4987037.
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    202. Nussenzweig R, Vanderberg J, Most H. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. IV. Dose response, specificity and humoral immunity. Mil Med. 1969 Sep; 134(10):1176-82. PMID: 4987036.
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    203. Lucia HL, Nussenzweig RS. Plasmodium chabaudi and Plasmodium vinckei: phagocytic activity of mouse reticuloendothelial system. Exp Parasitol. 1969 Aug; 25(1):319-23. PMID: 5362592.
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    204. Nussenzweig RS, Vanderberg JP, Most H, Orton C. Specificity of protective immunity produced by x-irradiated Plasmodium berghei sporozoites. Nature. 1969 May 03; 222(5192):488-9. PMID: 5768632.
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    205. Vanderberg JP, Nussenzweig RS, Most H, Orton CG. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. II. Effects of radiation on sporozoites. J Parasitol. 1968 Dec; 54(6):1175-80. PMID: 5757691.
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    206. Jahiel RI, Nussenzweig RS, Vanderberg J, Vilcek J. Anti-malarial effect of interferon inducers at different stages of development of Plasmodium berghei in the mouse. Nature. 1968 Nov 16; 220(5168):710-1. PMID: 5688147.
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    207. Vanderberg JP, Nussenzweig RS, Most H. Further studies on the Plasmodium berghei-Anopheles stephensi--rodent system of mammalian malaria. J Parasitol. 1968 Oct; 54(5):1009-16. PMID: 4919047.
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    208. Jahiel RI, Vilcek J, Nussenzweig R, Vanderberg J. Interferon inducers protect mice against plasmodium berghei malaria. Science. 1968 Aug 23; 161(3843):802-4. PMID: 5663811.
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    209. Nussenzweig RS, Vanderberg J, Most H, Orton C. Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei. Nature. 1967 Oct 14; 216(5111):160-2. PMID: 6057225.
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    210. Nussenzweig RS. Increased nonspecific resstance to malaria produced by administration of killed Corynebacterium parvum. Exp Parasitol. 1967 Oct; 21(2):224-31. PMID: 6080011.
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    211. Nussenzweig RS, Yoeli M, Most H. Studies on the protective effect of Plasmodium chabaudi infection in mice upon a subsequent infection with another rodent malaria species, plasmodium vinckei. Mil Med. 1966 Sep; 131(9):Suppl:1237-42. PMID: 4957831.
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    212. Most H, Nussenzweig RS, Vanderberg J, Herman R, Yoeli M. Susceptibility of genetically standardized (JAX) mouse strains to sporozoite- and blood-induced Plasmodium berghei infections. Mil Med. 1966 Sep; 131(9):Suppl:915-8. PMID: 4957839.
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    213. Nussenzweig R, Herman R, Vanderberg J, Yoeli M, Most H. Studies on sporozoite-induced infections of rodent malaria. 3. The course of sporozoite-induced Plasmodium berghei in different hosts. Am J Trop Med Hyg. 1966 Sep; 15(5):684-9. PMID: 5917626.
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    214. NUSSENZWEIG RS, MERRYMAN C, BENACERRAF B. ELECTROPHORETIC SEPARATION AND PROPERTIES OF MOUSE ANTIHAPTEN ANTIBODIES INVOLVED IN PASSIVE CUTANEOUS ANAPHYLAXIS AND PASSIVE HEMOLYSIS. J Exp Med. 1964 Aug 01; 120:315-28. PMID: 14206442; PMCID: PMC2137726.
    215. ROCHE J, MICHEL R, NUSSENZWEIG RS, MELDOLESI MF. [On the metabolism of 3,5-diiodo-L-tyrosine in the rabbit]. C R Seances Soc Biol Fil. 1960; 154:1144-8. PMID: 13742449.
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    216. ROCHE J, MICHEL R, NUSSENZWEIG RS, VOLPERT E. [On the predominance of glucuronic acid conjugates in rabbit urine following injection of 3, 5, 3'-triiodothyroaetic acid and 3, 5, 3'-triiodo-L-thyronine]. C R Seances Soc Biol Fil. 1960; 154:77-80. PMID: 14438075.
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    217. NUSSENZWEIG RS, DEANE MP. [Studies on the transmission of Toxoplasma gondii. I. Experiences with triatomes]. Rev Bras Malariol Doencas Trop. 1958 Oct; 10:543-50. PMID: 14427943.
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    218. NUSSENZWEIG RS. [Toxoplasmosis; serological examination by the dye test in blood donors]. Gaz Med Port. 1958 Mar-Apr; 11(2):243-7. PMID: 13574372.
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    219. NUSSENZWEIG V, NUSSENZWEIG RS, DE FREITAS JL, AMATO NETO V, BIANCALANA A, KLOETZEL J. [Effects of physical and chemical agents of Trypanosoma cruzi in vitro]. Hospital (Rio J). 1954 May; 45(5):589-99. PMID: 13183561.
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