Loading...
Header Logo
Keywords
Last Name
Institution

Professor Robert Edward Sinden

Title[no position]
Institution[no institution name]
Address[no address]
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Phillips MA, Lotharius J, Marsh K, White J, Dayan A, White KL, Njoroge JW, El Mazouni F, Lao Y, Kokkonda S, Tomchick DR, Deng X, Laird T, Bhatia SN, March S, Ng CL, Fidock DA, Wittlin S, Lafuente-Monasterio M, Benito FJ, Alonso LM, Martinez MS, Jimenez-Diaz MB, Bazaga SF, Angulo-Barturen I, Haselden JN, Louttit J, Cui Y, Sridhar A, Zeeman AM, Kocken C, Sauerwein R, Dechering K, Avery VM, Duffy S, Delves M, Sinden R, Ruecker A, Wickham KS, Rochford R, Gahagen J, Iyer L, Riccio E, Mirsalis J, Bathhurst I, Rueckle T, Ding X, Campo B, Leroy D, Rogers MJ, Rathod PK, Burrows JN, Charman SA. A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci Transl Med. 2015 Jul 15; 7(296):296ra111. PMID: 26180101; PMCID: PMC4539048.
    2. Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A. A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature. 2015 06 18; 522(7556):315-20. PMID: 26085270; PMCID: PMC4700930.
    3. Kapulu MC, Da DF, Miura K, Li Y, Blagborough AM, Churcher TS, Nikolaeva D, Williams AR, Goodman AL, Sangare I, Turner AV, Cottingham MG, Nicosia A, Straschil U, Tsuboi T, Gilbert SC, Long CA, Sinden RE, Draper SJ, Hill AV, Cohuet A, Biswas S. Comparative assessment of transmission-blocking vaccine candidates against Plasmodium falciparum. Sci Rep. 2015 Jun 11; 5:11193. PMID: 26063320; PMCID: PMC4463016.
    4. Wu Y, Sinden RE, Churcher TS, Tsuboi T, Yusibov V. Development of malaria transmission-blocking vaccines: from concept to product. Adv Parasitol. 2015 Jun; 89:109-52. PMID: 26003037.
      View in: PubMed
    5. Miguel-Blanco C, Lelièvre J, Delves MJ, Bardera AI, Presa JL, López-Barragán MJ, Ruecker A, Marques S, Sinden RE, Herreros E. Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. Antimicrob Agents Chemother. 2015; 59(6):3298-305. PMID: 25801574; PMCID: PMC4432159.
    6. Sinden RE. The cell biology of malaria infection of mosquito: advances and opportunities. Cell Microbiol. 2015 Apr; 17(4):451-66. PMID: 25557077; PMCID: PMC4409862.
    7. Da DF, Churcher TS, Yerbanga RS, Yaméogo B, Sangaré I, Ouedraogo JB, Sinden RE, Blagborough AM, Cohuet A. Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions. Exp Parasitol. 2015 Feb; 149:74-83. PMID: 25541384.
      View in: PubMed
    8. Sala KA, Nishiura H, Upton LM, Zakutansky SE, Delves MJ, Iyori M, Mizutani M, Sinden RE, Yoshida S, Blagborough AM. The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro. Vaccine. 2015 Jan 09; 33(3):437-45. PMID: 25454088.
      View in: PubMed
    9. Malmquist NA, Sundriyal S, Caron J, Chen P, Witkowski B, Menard D, Suwanarusk R, Renia L, Nosten F, Jiménez-Díaz MB, Angulo-Barturen I, Santos Martínez M, Ferrer S, Sanz LM, Gamo FJ, Wittlin S, Duffy S, Avery VM, Ruecker A, Delves MJ, Sinden RE, Fuchter MJ, Scherf A. Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans. Antimicrob Agents Chemother. 2015 Feb; 59(2):950-9. PMID: 25421480; PMCID: PMC4335868.
    10. Upton LM, Brock PM, Churcher TS, Ghani AC, Gething PW, Delves MJ, Sala KA, Leroy D, Sinden RE, Blagborough AM. Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations. Antimicrob Agents Chemother. 2015 Jan; 59(1):490-7. PMID: 25385107; PMCID: PMC4291391.
    11. Hodgson SH, Ewer KJ, Bliss CM, Edwards NJ, Rampling T, Anagnostou NA, de Barra E, Havelock T, Bowyer G, Poulton ID, de Cassan S, Longley R, Illingworth JJ, Douglas AD, Mange PB, Collins KA, Roberts R, Gerry S, Berrie E, Moyle S, Colloca S, Cortese R, Sinden RE, Gilbert SC, Bejon P, Lawrie AM, Nicosia A, Faust SN, Hill AV. Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals. J Infect Dis. 2015 Apr 01; 211(7):1076-86. PMID: 25336730; PMCID: PMC4354983.
    12. Ruecker A, Mathias DK, Straschil U, Churcher TS, Dinglasan RR, Leroy D, Sinden RE, Delves MJ. A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs. Antimicrob Agents Chemother. 2014 Dec; 58(12):7292-302. PMID: 25267664; PMCID: PMC4249523.
    13. Marques SR, Ramakrishnan C, Carzaniga R, Blagborough AM, Delves MJ, Talman AM, Sinden RE. An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission. Cell Microbiol. 2015 Feb; 17(2):191-206. PMID: 25154861; PMCID: PMC4441282.
    14. Talman AM, Prieto JH, Marques S, Ubaida-Mohien C, Lawniczak M, Wass MN, Xu T, Frank R, Ecker A, Stanway RS, Krishna S, Sternberg MJ, Christophides GK, Graham DR, Dinglasan RR, Yates JR, Sinden RE. Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility. Malar J. 2014 Aug 13; 13:315. PMID: 25124718; PMCID: PMC4150949.
    15. Mizutani M, Iyori M, Blagborough AM, Fukumoto S, Funatsu T, Sinden RE, Yoshida S. Baculovirus-vectored multistage Plasmodium vivax vaccine induces both protective and transmission-blocking immunities against transgenic rodent malaria parasites. Infect Immun. 2014 Oct; 82(10):4348-57. PMID: 25092912; PMCID: PMC4187867.
    16. Kan A, Tan YH, Angrisano F, Hanssen E, Rogers KL, Whitehead L, Mollard VP, Cozijnsen A, Delves MJ, Crawford S, Sinden RE, McFadden GI, Leckie C, Bailey J, Baum J. Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility. Cell Microbiol. 2014 May; 16(5):734-50. PMID: 24612056; PMCID: PMC4286792.
    17. Williams AR, Zakutansky SE, Miura K, Dicks MD, Churcher TS, Jewell KE, Vaughan AM, Turner AV, Kapulu MC, Michel K, Long CA, Sinden RE, Hill AV, Draper SJ, Biswas S. Immunisation against a serine protease inhibitor reduces intensity of Plasmodium berghei infection in mosquitoes. Int J Parasitol. 2013 Oct; 43(11):869-74. PMID: 23872520; PMCID: PMC3775004.
    18. Delves MJ, Ruecker A, Straschil U, Lelièvre J, Marques S, López-Barragán MJ, Herreros E, Sinden RE. Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs. Antimicrob Agents Chemother. 2013 Jul; 57(7):3268-74. PMID: 23629698; PMCID: PMC3697345.
    19. Nilsen A, LaCrue AN, White KL, Forquer IP, Cross RM, Marfurt J, Mather MW, Delves MJ, Shackleford DM, Saenz FE, Morrisey JM, Steuten J, Mutka T, Li Y, Wirjanata G, Ryan E, Duffy S, Kelly JX, Sebayang BF, Zeeman AM, Noviyanti R, Sinden RE, Kocken CHM, Price RN, Avery VM, Angulo-Barturen I, Jiménez-Díaz MB, Ferrer S, Herreros E, Sanz LM, Gamo FJ, Bathurst I, Burrows JN, Siegl P, Guy RK, Winter RW, Vaidya AB, Charman SA, Kyle DE, Manetsch R, Riscoe MK. Quinolone-3-diarylethers: a new class of antimalarial drug. Sci Transl Med. 2013 Mar 20; 5(177):177ra37. PMID: 23515079; PMCID: PMC4227885.
    20. Blagborough AM, Churcher TS, Upton LM, Ghani AC, Gething PW, Sinden RE. Transmission-blocking interventions eliminate malaria from laboratory populations. Nat Commun. 2013; 4:1812. PMID: 23652000; PMCID: PMC3674233.
    21. Ramakrishnan C, Delves MJ, Lal K, Blagborough AM, Butcher G, Baker KW, Sinden RE. Laboratory maintenance of rodent malaria parasites. Methods Mol Biol. 2013; 923:51-72. PMID: 22990771.
      View in: PubMed
    22. Blagborough AM, Delves MJ, Ramakrishnan C, Lal K, Butcher G, Sinden RE. Assessing transmission blockade in Plasmodium spp. Methods Mol Biol. 2013; 923:577-600. PMID: 22990806.
      View in: PubMed
    23. Ewer KJ, O'Hara GA, Duncan CJ, Collins KA, Sheehy SH, Reyes-Sandoval A, Goodman AL, Edwards NJ, Elias SC, Halstead FD, Longley RJ, Rowland R, Poulton ID, Draper SJ, Blagborough AM, Berrie E, Moyle S, Williams N, Siani L, Folgori A, Colloca S, Sinden RE, Lawrie AM, Cortese R, Gilbert SC, Nicosia A, Hill AV. Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation. Nat Commun. 2013; 4:2836. PMID: 24284865; PMCID: PMC3868203.
    24. Oakes RD, Kurian D, Bromley E, Ward C, Lal K, Blake DP, Reid AJ, Pain A, Sinden RE, Wastling JM, Tomley FM. The rhoptry proteome of Eimeria tenella sporozoites. Int J Parasitol. 2013 Feb; 43(2):181-8. PMID: 23262303.
      View in: PubMed
    25. Sheehy SH, Duncan CJ, Elias SC, Choudhary P, Biswas S, Halstead FD, Collins KA, Edwards NJ, Douglas AD, Anagnostou NA, Ewer KJ, Havelock T, Mahungu T, Bliss CM, Miura K, Poulton ID, Lillie PJ, Antrobus RD, Berrie E, Moyle S, Gantlett K, Colloca S, Cortese R, Long CA, Sinden RE, Gilbert SC, Lawrie AM, Doherty T, Faust SN, Nicosia A, Hill AV, Draper SJ. ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. Mol Ther. 2012 Dec; 20(12):2355-68. PMID: 23089736; PMCID: PMC3519995.
    26. Churcher TS, Blagborough AM, Delves M, Ramakrishnan C, Kapulu MC, Williams AR, Biswas S, Da DF, Cohuet A, Sinden RE. Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding Assay. Int J Parasitol. 2012 Oct; 42(11):1037-44. PMID: 23023048.
      View in: PubMed
    27. Delves MJ, Ramakrishnan C, Blagborough AM, Leroy D, Wells TN, Sinden RE. A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines. Int J Parasitol. 2012 Oct; 42(11):999-1006. PMID: 23023046.
      View in: PubMed
    28. Guttery DS, Poulin B, Ferguson DJ, Szöor B, Wickstead B, Carroll PL, Ramakrishnan C, Brady D, Patzewitz EM, Straschil U, Solyakov L, Green JL, Sinden RE, Tobin AB, Holder AA, Tewari R. A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathog. 2012 Sep; 8(9):e1002948. PMID: 23028336; PMCID: PMC3447748.
    29. Sinden RE, Blagborough AM, Churcher T, Ramakrishnan C, Biswas S, Delves MJ. The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium. Trends Parasitol. 2012 Nov; 28(11):457-65. PMID: 22980759.
      View in: PubMed
    30. Biagini GA, Fisher N, Shone AE, Mubaraki MA, Srivastava A, Hill A, Antoine T, Warman AJ, Davies J, Pidathala C, Amewu RK, Leung SC, Sharma R, Gibbons P, Hong DW, Pacorel B, Lawrenson AS, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Stocks PA, Nixon GL, Chadwick J, Hemingway J, Delves MJ, Sinden RE, Zeeman AM, Kocken CH, Berry NG, O'Neill PM, Ward SA. Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8298-303. PMID: 22566611; PMCID: PMC3361392.
    31. Sinden RE, Carter R, Drakeley C, Leroy D. The biology of sexual development of Plasmodium: the design and implementation of transmission-blocking strategies. Malar J. 2012 Mar 16; 11:70. PMID: 22424474; PMCID: PMC3315749.
    32. Angrisano F, Riglar DT, Sturm A, Volz JC, Delves MJ, Zuccala ES, Turnbull L, Dekiwadia C, Olshina MA, Marapana DS, Wong W, Mollard V, Bradin CH, Tonkin CJ, Gunning PW, Ralph SA, Whitchurch CB, Sinden RE, Cowman AF, McFadden GI, Baum J. Spatial localisation of actin filaments across developmental stages of the malaria parasite. PLoS One. 2012; 7(2):e32188. PMID: 22389687; PMCID: PMC3289632.
    33. Delves M, Plouffe D, Scheurer C, Meister S, Wittlin S, Winzeler EA, Sinden RE, Leroy D. The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites. PLoS Med. 2012 Feb; 9(2):e1001169. PMID: 22363211; PMCID: PMC3283556.
    34. Wass MN, Stanway R, Blagborough AM, Lal K, Prieto JH, Raine D, Sternberg MJ, Talman AM, Tomley F, Yates J, Sinden RE. Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls. Parasitology. 2012 Aug; 139(9):1131-45. PMID: 22336136; PMCID: PMC3417538.
    35. Goodman AL, Blagborough AM, Biswas S, Wu Y, Hill AV, Sinden RE, Draper SJ. A viral vectored prime-boost immunization regime targeting the malaria Pfs25 antigen induces transmission-blocking activity. PLoS One. 2011; 6(12):e29428. PMID: 22216279; PMCID: PMC3247263.
    36. Angrisano F, Delves MJ, Sturm A, Mollard V, McFadden GI, Sinden RE, Baum J. A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle. Mol Biochem Parasitol. 2012 Mar-Apr; 182(1-2):93-6. PMID: 22138565.
      View in: PubMed
    37. Talman AM, Lacroix C, Marques SR, Blagborough AM, Carzaniga R, Ménard R, Sinden RE. PbGEST mediates malaria transmission to both mosquito and vertebrate host. Mol Microbiol. 2011 Oct; 82(2):462-74. PMID: 21958024.
      View in: PubMed
    38. Siden-Kiamos I, Ganter M, Kunze A, Hliscs M, Steinbüchel M, Mendoza J, Sinden RE, Louis C, Matuschewski K. Stage-specific depletion of myosin A supports an essential role in motility of malarial ookinetes. Cell Microbiol. 2011 Dec; 13(12):1996-2006. PMID: 21899701.
      View in: PubMed
    39. Ramakrishnan C, Dessens JT, Armson R, Pinto SB, Talman AM, Blagborough AM, Sinden RE. Vital functions of the malarial ookinete protein, CTRP, reside in the A domains. Int J Parasitol. 2011 Aug 15; 41(10):1029-39. PMID: 21729699; PMCID: PMC4068204.
    40. Porter DW, Thompson FM, Berthoud TK, Hutchings CL, Andrews L, Biswas S, Poulton I, Prieur E, Correa S, Rowland R, Lang T, Williams J, Gilbert SC, Sinden RE, Todryk S, Hill AV. A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine. Vaccine. 2011 Oct 06; 29(43):7514-22. PMID: 21501642; PMCID: PMC3195259.
    41. Slavic K, Delves MJ, Prudêncio M, Talman AM, Straschil U, Derbyshire ET, Xu Z, Sinden RE, Mota MM, Morin C, Tewari R, Krishna S, Staines HM. Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle. Antimicrob Agents Chemother. 2011 Jun; 55(6):2824-30. PMID: 21402842; PMCID: PMC3101457.
    42. Alonso PL, Brown G, Arevalo-Herrera M, Binka F, Chitnis C, Collins F, Doumbo OK, Greenwood B, Hall BF, Levine MM, Mendis K, Newman RD, Plowe CV, Rodríguez MH, Sinden R, Slutsker L, Tanner M. A research agenda to underpin malaria eradication. PLoS Med. 2011 Jan 25; 8(1):e1000406. PMID: 21311579; PMCID: PMC3026687.
    43. Farrance CE, Chichester JA, Musiychuk K, Shamloul M, Rhee A, Manceva SD, Jones RM, Mamedov T, Sharma S, Mett V, Streatfield SJ, Roeffen W, van de Vegte-Bolmer M, Sauerwein RW, Wu Y, Muratova O, Miller L, Duffy P, Sinden R, Yusibov V. Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity. Hum Vaccin. 2011 Jan-Feb; 7 Suppl:191-8. PMID: 21266847.
      View in: PubMed
    44. Churcher TS, Dawes EJ, Sinden RE, Christophides GK, Koella JC, Basáñez MG. Population biology of malaria within the mosquito: density-dependent processes and potential implications for transmission-blocking interventions. Malar J. 2010 Nov 04; 9:311. PMID: 21050427; PMCID: PMC2988043.
    45. Kambris Z, Blagborough AM, Pinto SB, Blagrove MS, Godfray HC, Sinden RE, Sinkins SP. Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae. PLoS Pathog. 2010 Oct 07; 6(10):e1001143. PMID: 20949079; PMCID: PMC2951381.
    46. Straschil U, Talman AM, Ferguson DJ, Bunting KA, Xu Z, Bailes E, Sinden RE, Holder AA, Smith EF, Coates JC. The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. PLoS One. 2010 Sep 23; 5(9):e12901. PMID: 20886115; PMCID: PMC2944832.
    47. Blagborough AM, Yoshida S, Sattabongkot J, Tsuboi T, Sinden RE. Intranasal and intramuscular immunization with Baculovirus Dual Expression System-based Pvs25 vaccine substantially blocks Plasmodium vivax transmission. Vaccine. 2010 Aug 23; 28(37):6014-20. PMID: 20637303.
      View in: PubMed
    48. Sinden RE, Talman A, Marques SR, Wass MN, Sternberg MJ. The flagellum in malarial parasites. Curr Opin Microbiol. 2010 Aug; 13(4):491-500. PMID: 20566299.
      View in: PubMed
    49. Talman AM, Blagborough AM, Sinden RE. A Plasmodium falciparum strain expressing GFP throughout the parasite's life-cycle. PLoS One. 2010 Feb 10; 5(2):e9156. PMID: 20161781; PMCID: PMC2819258.
    50. Delves MJ, Sinden RE. A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies. Malar J. 2010 Jan 29; 9:35. PMID: 20113492; PMCID: PMC2824803.
    51. Sinden RE. A biologist's perspective on malaria vaccine development. Hum Vaccin. 2010 Jan; 6(1):3-11. PMID: 19946205.
      View in: PubMed
    52. Dawes EJ, Churcher TS, Zhuang S, Sinden RE, Basáñez MG. Anopheles mortality is both age- and Plasmodium-density dependent: implications for malaria transmission. Malar J. 2009 Oct 12; 8:228. PMID: 19822012; PMCID: PMC2770541.
    53. Lal K, Bromley E, Oakes R, Prieto JH, Sanderson SJ, Kurian D, Hunt L, Yates JR, Wastling JM, Sinden RE, Tomley FM. Proteomic comparison of four Eimeria tenella life-cycle stages: unsporulated oocyst, sporulated oocyst, sporozoite and second-generation merozoite. Proteomics. 2009 Oct; 9(19):4566-76. PMID: 19795439; PMCID: PMC2947549.
    54. Bushell ES, Ecker A, Schlegelmilch T, Goulding D, Dougan G, Sinden RE, Christophides GK, Kafatos FC, Vlachou D. Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector. PLoS Pathog. 2009 Aug; 5(8):e1000539. PMID: 19662167; PMCID: PMC2715856.
    55. Sinden RE. Malaria, sexual development and transmission: retrospect and prospect. Parasitology. 2009 Oct; 136(12):1427-34. PMID: 19660156.
      View in: PubMed
    56. Blagborough AM, Sinden RE. Plasmodium berghei HAP2 induces strong malaria transmission-blocking immunity in vivo and in vitro. Vaccine. 2009 Aug 20; 27(38):5187-94. PMID: 19596419.
      View in: PubMed
    57. Dawes EJ, Zhuang S, Sinden RE, Basáñez MG. The temporal dynamics of Plasmodium density through the sporogonic cycle within Anopheles mosquitoes. Trans R Soc Trop Med Hyg. 2009 Dec; 103(12):1197-8. PMID: 19349054.
      View in: PubMed
    58. Lal K, Prieto JH, Bromley E, Sanderson SJ, Yates JR, Wastling JM, Tomley FM, Sinden RE. Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Proteomics. 2009 Mar; 9(5):1142-51. PMID: 19206106; PMCID: PMC2706521.
    59. Tufet-Bayona M, Janse CJ, Khan SM, Waters AP, Sinden RE, Franke-Fayard B. Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites. Mol Biochem Parasitol. 2009 Jul; 166(1):22-31. PMID: 19428669.
      View in: PubMed
    60. Sinden RE. Reality check for malaria proteomics. Genome Biol. 2009; 10(2):211. PMID: 19291264.
      View in: PubMed
    61. Lal K, Delves MJ, Bromley E, Wastling JM, Tomley FM, Sinden RE. Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. Int J Parasitol. 2009 Jun; 39(7):755-61. PMID: 19136003.
      View in: PubMed
    62. Bass C, Nikou D, Blagborough AM, Vontas J, Sinden RE, Williamson MS, Field LM. PCR-based detection of Plasmodium in Anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods. Malar J. 2008 Sep 15; 7:177. PMID: 18793416; PMCID: PMC2553798.
    63. Ecker A, Bushell ES, Tewari R, Sinden RE. Reverse genetics screen identifies six proteins important for malaria development in the mosquito. Mol Microbiol. 2008 Oct; 70(1):209-20. PMID: 18761621; PMCID: PMC2658712.
    64. Xia D, Sanderson SJ, Jones AR, Prieto JH, Yates JR, Bromley E, Tomley FM, Lal K, Sinden RE, Brunk BP, Roos DS, Wastling JM. The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation. Genome Biol. 2008; 9(7):R116. PMID: 18644147; PMCID: PMC2530874.
    65. Sanderson SJ, Xia D, Prieto H, Yates J, Heiges M, Kissinger JC, Bromley E, Lal K, Sinden RE, Tomley F, Wastling JM. Determining the protein repertoire of Cryptosporidium parvum sporozoites. Proteomics. 2008 Apr; 8(7):1398-414. PMID: 18306179; PMCID: PMC2770187.
    66. Liu Y, Tewari R, Ning J, Blagborough AM, Garbom S, Pei J, Grishin NV, Steele RE, Sinden RE, Snell WJ, Billker O. The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes. Genes Dev. 2008 Apr 15; 22(8):1051-68. PMID: 18367645; PMCID: PMC2335326.
    67. Thompson FM, Porter DW, Okitsu SL, Westerfeld N, Vogel D, Todryk S, Poulton I, Correa S, Hutchings C, Berthoud T, Dunachie S, Andrews L, Williams JL, Sinden R, Gilbert SC, Pluschke G, Zurbriggen R, Hill AV. Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial. PLoS One. 2008 Jan 30; 3(1):e1493. PMID: 18231580; PMCID: PMC2204057.
    68. Sinden RE, Dawes EJ, Alavi Y, Waldock J, Finney O, Mendoza J, Butcher GA, Andrews L, Hill AV, Gilbert SC, Basáñez MG. Progression of Plasmodium berghei through Anopheles stephensi is density-dependent. PLoS Pathog. 2007 Dec 28; 3(12):e195. PMID: 18166078; PMCID: PMC2156095.
    69. Yoshida S, Shimada Y, Kondoh D, Kouzuma Y, Ghosh AK, Jacobs-Lorena M, Sinden RE. Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development. PLoS Pathog. 2007 Dec; 3(12):e192. PMID: 18159942; PMCID: PMC2151087.
    70. Sinden RE. Malaria, mosquitoes and the legacy of Ronald Ross. Bull World Health Organ. 2007 Nov; 85(11):894-6. PMID: 18038083; PMCID: PMC2636258.
    71. Carter V, Nacer AM, Underhill A, Sinden RE, Hurd H. Minimum requirements for ookinete to oocyst transformation in Plasmodium. Int J Parasitol. 2007 Sep; 37(11):1221-32. PMID: 17482621; PMCID: PMC2474741.
    72. Raine JD, Ecker A, Mendoza J, Tewari R, Stanway RR, Sinden RE. Female inheritance of malarial lap genes is essential for mosquito transmission. PLoS Pathog. 2007 Mar; 3(3):e30. PMID: 17335349; PMCID: PMC1808070.
    73. Le Chat L, Sinden RE, Dessens JT. The role of metacaspase 1 in Plasmodium berghei development and apoptosis. Mol Biochem Parasitol. 2007 May; 153(1):41-7. PMID: 17335919; PMCID: PMC2075530.
    74. Ecker A, Pinto SB, Baker KW, Kafatos FC, Sinden RE. Plasmodium berghei: plasmodium perforin-like protein 5 is required for mosquito midgut invasion in Anopheles stephensi. Exp Parasitol. 2007 Aug; 116(4):504-8. PMID: 17367780; PMCID: PMC1916484.
    75. Walther M, Woodruff J, Edele F, Jeffries D, Tongren JE, King E, Andrews L, Bejon P, Gilbert SC, De Souza JB, Sinden R, Hill AV, Riley EM. Innate immune responses to human malaria: heterogeneous cytokine responses to blood-stage Plasmodium falciparum correlate with parasitological and clinical outcomes. J Immunol. 2006 Oct 15; 177(8):5736-45. PMID: 17015763.
      View in: PubMed
    76. Dunachie SJ, Walther M, Epstein JE, Keating S, Berthoud T, Andrews L, Andersen RF, Bejon P, Goonetilleke N, Poulton I, Webster DP, Butcher G, Watkins K, Sinden RE, Levine GL, Richie TL, Schneider J, Kaslow D, Gilbert SC, Carucci DJ, Hill AV. A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge. Infect Immun. 2006 Oct; 74(10):5933-42. PMID: 16988273; PMCID: PMC1594937.
    77. Ramjanee S, Robertson JS, Franke-Fayard B, Sinha R, Waters AP, Janse CJ, Wu Y, Blagborough AM, Saul A, Sinden RE. The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials. Vaccine. 2007 Jan 15; 25(5):886-94. PMID: 17049690.
      View in: PubMed
    78. Siden-Kiamos I, Ecker A, Nybäck S, Louis C, Sinden RE, Billker O. Plasmodium berghei calcium-dependent protein kinase 3 is required for ookinete gliding motility and mosquito midgut invasion. Mol Microbiol. 2006 Jun; 60(6):1355-63. PMID: 16796674; PMCID: PMC1513514.
    79. Walther M, Thompson FM, Dunachie S, Keating S, Todryk S, Berthoud T, Andrews L, Andersen RF, Moore A, Gilbert SC, Poulton I, Dubovsky F, Tierney E, Correa S, Huntcooke A, Butcher G, Williams J, Sinden RE, Hill AV. Safety, immunogenicity, and efficacy of prime-boost immunization with recombinant poxvirus FP9 and modified vaccinia virus Ankara encoding the full-length Plasmodium falciparum circumsporozoite protein. Infect Immun. 2006 May; 74(5):2706-16. PMID: 16622207; PMCID: PMC1459746.
    80. Dunachie SJ, Walther M, Vuola JM, Webster DP, Keating SM, Berthoud T, Andrews L, Bejon P, Poulton I, Butcher G, Watkins K, Sinden RE, Leach A, Moris P, Tornieporth N, Schneider J, Dubovsky F, Tierney E, Williams J, Heppner DG, Gilbert SC, Cohen J, Hill AV. A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS,S/AS02A and MVA-CS. Vaccine. 2006 Apr 05; 24(15):2850-9. PMID: 16434127.
      View in: PubMed
    81. Ecker A, Moon R, Sinden RE, Billker O. Generation of gene targeting constructs for Plasmodium berghei by a PCR-based method amenable to high throughput applications. Mol Biochem Parasitol. 2006 Feb; 145(2):265-8. PMID: 16290088.
      View in: PubMed
    82. Mahairaki V, Lycett G, Sidén-Kiamos I, Sinden RE, Louis C. Close association of invading Plasmodium berghei and beta integrin in the Anopheles gambiae midgut. Arch Insect Biochem Physiol. 2005 Sep; 60(1):13-9. PMID: 16116619.
      View in: PubMed
    83. Walther M, Tongren JE, Andrews L, Korbel D, King E, Fletcher H, Andersen RF, Bejon P, Thompson F, Dunachie SJ, Edele F, de Souza JB, Sinden RE, Gilbert SC, Riley EM, Hill AV. Upregulation of TGF-beta, FOXP3, and CD4+CD25+ regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity. 2005 Sep; 23(3):287-96. PMID: 16169501.
      View in: PubMed
    84. Kotsyfakis M, Ehret-Sabatier L, Siden-Kiamos I, Mendoza J, Sinden RE, Louis C. Plasmodium berghei ookinetes bind to Anopheles gambiae and Drosophila melanogaster annexins. Mol Microbiol. 2005 Jul; 57(1):171-9. PMID: 15948958.
      View in: PubMed
    85. Plebanski M, Hannan CM, Behboudi S, Flanagan KL, Apostolopoulos V, Sinden RE, Hill AV. Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8 T-cell responses. Immunol Cell Biol. 2005 Jun; 83(3):307-12. PMID: 15877610.
      View in: PubMed
    86. Xu X, Dong Y, Abraham EG, Kocan A, Srinivasan P, Ghosh AK, Sinden RE, Ribeiro JM, Jacobs-Lorena M, Kafatos FC, Dimopoulos G. Transcriptome analysis of Anopheles stephensi-Plasmodium berghei interactions. Mol Biochem Parasitol. 2005 Jul; 142(1):76-87. PMID: 15907562.
      View in: PubMed
    87. Webster DP, Dunachie S, Vuola JM, Berthoud T, Keating S, Laidlaw SM, McConkey SJ, Poulton I, Andrews L, Andersen RF, Bejon P, Butcher G, Sinden R, Skinner MA, Gilbert SC, Hill AV. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc Natl Acad Sci U S A. 2005 Mar 29; 102(13):4836-41. PMID: 15781866; PMCID: PMC555695.
    88. Korten S, Anderson RJ, Hannan CM, Sheu EG, Sinden R, Gadola S, Taniguchi M, Hill AV. Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice. Infect Immun. 2005 Feb; 73(2):849-58. PMID: 15664925; PMCID: PMC546932.
    89. Hall N, Karras M, Raine JD, Carlton JM, Kooij TW, Berriman M, Florens L, Janssen CS, Pain A, Christophides GK, James K, Rutherford K, Harris B, Harris D, Churcher C, Quail MA, Ormond D, Doggett J, Trueman HE, Mendoza J, Bidwell SL, Rajandream MA, Carucci DJ, Yates JR, Kafatos FC, Janse CJ, Barrell B, Turner CM, Waters AP, Sinden RE. A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science. 2005 Jan 07; 307(5706):82-6. PMID: 15637271.
      View in: PubMed
    90. Walther M, Dunachie S, Keating S, Vuola JM, Berthoud T, Schmidt A, Maier C, Andrews L, Andersen RF, Gilbert S, Poulton I, Webster D, Dubovsky F, Tierney E, Sarpotdar P, Correa S, Huntcooke A, Butcher G, Williams J, Sinden RE, Thornton GB, Hill AV. Safety, immunogenicity and efficacy of a pre-erythrocytic malaria candidate vaccine, ICC-1132 formulated in Seppic ISA 720. Vaccine. 2005 Jan 04; 23(7):857-64. PMID: 15603885.
      View in: PubMed
    91. Sinden RE. A proteomic analysis of malaria biology: integration of old literature and new technologies. Int J Parasitol. 2004 Dec; 34(13-14):1441-50. PMID: 15582521.
      View in: PubMed
    92. Khater EI, Sinden RE, Dessens JT. A malaria membrane skeletal protein is essential for normal morphogenesis, motility, and infectivity of sporozoites. J Cell Biol. 2004 Nov 08; 167(3):425-32. PMID: 15533999; PMCID: PMC2172497.
    93. Trueman HE, Raine JD, Florens L, Dessens JT, Mendoza J, Johnson J, Waller CC, Delrieu I, Holders AA, Langhorne J, Carucci DJ, Yates JR, Sinden RE. Functional characterization of an LCCL-lectin domain containing protein family in Plasmodium berghei. J Parasitol. 2004 Oct; 90(5):1062-71. PMID: 15562607.
      View in: PubMed
    94. Sam-Yellowe TY, Florens L, Wang T, Raine JD, Carucci DJ, Sinden R, Yates JR. Proteome analysis of rhoptry-enriched fractions isolated from Plasmodium merozoites. J Proteome Res. 2004 Sep-Oct; 3(5):995-1001. PMID: 15473688.
      View in: PubMed
    95. Franke-Fayard B, Trueman H, Ramesar J, Mendoza J, van der Keur M, van der Linden R, Sinden RE, Waters AP, Janse CJ. A Plasmodium berghei reference line that constitutively expresses GFP at a high level throughout the complete life cycle. Mol Biochem Parasitol. 2004 Sep; 137(1):23-33. PMID: 15279948.
      View in: PubMed
    96. Sinden RE, Alavi Y, Raine JD. Mosquito--malaria interactions: a reappraisal of the concepts of susceptibility and refractoriness. Insect Biochem Mol Biol. 2004 Jul; 34(7):625-9. PMID: 15242703.
      View in: PubMed
    97. Anderson RJ, Hannan CM, Gilbert SC, Laidlaw SM, Sheu EG, Korten S, Sinden R, Butcher GA, Skinner MA, Hill AV. Enhanced CD8+ T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus. J Immunol. 2004 Mar 01; 172(5):3094-100. PMID: 14978115.
      View in: PubMed
    98. Dessens JT, Sinden RE, Claudianos C. LCCL proteins of apicomplexan parasites. Trends Parasitol. 2004 Mar; 20(3):102-8. PMID: 16482225.
      View in: PubMed
    99. Arai M, Alavi YI, Mendoza J, Billker O, Sinden RE. Isonicotinic acid hydrazide: an anti-tuberculosis drug inhibits malarial transmission in the mosquito gut. Exp Parasitol. 2004 Jan-Feb; 106(1-2):30-6. PMID: 15013786.
      View in: PubMed
    100. Alavi Y, Arai M, Mendoza J, Tufet-Bayona M, Sinha R, Fowler K, Billker O, Franke-Fayard B, Janse CJ, Waters A, Sinden RE. The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti. Int J Parasitol. 2003 Aug; 33(9):933-43. PMID: 12906877.
      View in: PubMed
    101. Dessens JT, Sidén-Kiamos I, Mendoza J, Mahairaki V, Khater E, Vlachou D, Xu XJ, Kafatos FC, Louis C, Dimopoulos G, Sinden RE. SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development. Mol Microbiol. 2003 Jul; 49(2):319-29. PMID: 12828632.
      View in: PubMed
    102. McConkey SJ, Reece WH, Moorthy VS, Webster D, Dunachie S, Butcher G, Vuola JM, Blanchard TJ, Gothard P, Watkins K, Hannan CM, Everaere S, Brown K, Kester KE, Cummings J, Williams J, Heppner DG, Pathan A, Flanagan K, Arulanantham N, Roberts MT, Roy M, Smith GL, Schneider J, Peto T, Sinden RE, Gilbert SC, Hill AV. Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nat Med. 2003 Jun; 9(6):729-35. PMID: 12766765.
      View in: PubMed
    103. Butcher GA, Sinden RE. Persistence of atovaquone in human sera following treatment: inhibition of Plasmodium falciparum development in vivo and in vitro. Am J Trop Med Hyg. 2003 Jan; 68(1):111-4. PMID: 12556158.
      View in: PubMed
    104. Billker O, Shaw MK, Jones IW, Ley SV, Mordue AJ, Sinden RE. Azadirachtin disrupts formation of organised microtubule arrays during microgametogenesis of Plasmodium berghei. J Eukaryot Microbiol. 2002 Nov-Dec; 49(6):489-97. PMID: 12503686.
      View in: PubMed
    105. Sinden RE. Molecular interactions between Plasmodium and its insect vectors. Cell Microbiol. 2002 Nov; 4(11):713-24. PMID: 12427094.
      View in: PubMed
    106. Alphey L, Beard CB, Billingsley P, Coetzee M, Crisanti A, Curtis C, Eggleston P, Godfray C, Hemingway J, Jacobs-Lorena M, James AA, Kafatos FC, Mukwaya LG, Paton M, Powell JR, Schneider W, Scott TW, Sina B, Sinden R, Sinkins S, Spielman A, Touré Y, Collins FH. Malaria control with genetically manipulated insect vectors. Science. 2002 Oct 04; 298(5591):119-21. PMID: 12364786.
      View in: PubMed
    107. Carlton JM, Angiuoli SV, Suh BB, Kooij TW, Pertea M, Silva JC, Ermolaeva MD, Allen JE, Selengut JD, Koo HL, Peterson JD, Pop M, Kosack DS, Shumway MF, Bidwell SL, Shallom SJ, van Aken SE, Riedmuller SB, Feldblyum TV, Cho JK, Quackenbush J, Sedegah M, Shoaibi A, Cummings LM, Florens L, Yates JR, Raine JD, Sinden RE, Harris MA, Cunningham DA, Preiser PR, Bergman LW, Vaidya AB, van Lin LH, Janse CJ, Waters AP, Smith HO, White OR, Salzberg SL, Venter JC, Fraser CM, Hoffman SL, Gardner MJ, Carucci DJ. Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature. 2002 Oct 03; 419(6906):512-9. PMID: 12368865.
      View in: PubMed
    108. Florens L, Washburn MP, Raine JD, Anthony RM, Grainger M, Haynes JD, Moch JK, Muster N, Sacci JB, Tabb DL, Witney AA, Wolters D, Wu Y, Gardner MJ, Holder AA, Sinden RE, Yates JR, Carucci DJ. A proteomic view of the Plasmodium falciparum life cycle. Nature. 2002 Oct 03; 419(6906):520-6. PMID: 12368866.
      View in: PubMed
    109. Claudianos C, Dessens JT, Trueman HE, Arai M, Mendoza J, Butcher GA, Crompton T, Sinden RE. A malaria scavenger receptor-like protein essential for parasite development. Mol Microbiol. 2002 Sep; 45(6):1473-84. PMID: 12354219.
      View in: PubMed
    110. Rodríguez MC, Margos G, Compton H, Ku M, Lanz H, Rodríguez MH, Sinden RE. Plasmodium berghei: routine production of pure gametocytes, extracellular gametes, zygotes, and ookinetes. Exp Parasitol. 2002 May; 101(1):73-6. PMID: 12243741.
      View in: PubMed
    111. Al-Olayan EM, Beetsma AL, Butcher GA, Sinden RE, Hurd H. Complete development of mosquito phases of the malaria parasite in vitro. Science. 2002 Jan 25; 295(5555):677-9. PMID: 11809973.
      View in: PubMed
    112. Gilbert SC, Schneider J, Hannan CM, Hu JT, Plebanski M, Sinden R, Hill AV. Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. Vaccine. 2002 Jan 15; 20(7-8):1039-45. PMID: 11803063.
      View in: PubMed
    113. Dimopoulos G, Kafatos FC, Waters AP, Sinden RE. Malaria parasites and the anopheles mosquito. Chem Immunol. 2002; 80:27-49. PMID: 12058645.
      View in: PubMed
    114. Sinden RE, Butcher GA, Beetsma AL. Maintenance of the Plasmodium berghei life cycle. Methods Mol Med. 2002; 72:25-40. PMID: 12125122.
      View in: PubMed
    115. Tomas AM, Margos G, Dimopoulos G, van Lin LH, de Koning-Ward TF, Sinha R, Lupetti P, Beetsma AL, Rodriguez MC, Karras M, Hager A, Mendoza J, Butcher GA, Kafatos F, Janse CJ, Waters AP, Sinden RE. P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions. EMBO J. 2001 Aug 01; 20(15):3975-83. PMID: 11483501; PMCID: PMC149139.
    116. Margos G, Navarette S, Butcher G, Davies A, Willers C, Sinden RE, Lachmann PJ. Interaction between host complement and mosquito-midgut-stage Plasmodium berghei. Infect Immun. 2001 Aug; 69(8):5064-71. PMID: 11447187; PMCID: PMC98601.
    117. Arai M, Billker O, Morris HR, Panico M, Delcroix M, Dixon D, Ley SV, Sinden RE. Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito. Mol Biochem Parasitol. 2001 Aug; 116(1):17-24. PMID: 11463462.
      View in: PubMed
    118. Raibaud A, Lupetti P, Paul RE, Mercati D, Brey PT, Sinden RE, Heuser JE, Dallai R. Cryofracture electron microscopy of the ookinete pellicle of Plasmodium gallinaceum reveals the existence of novel pores in the alveolar membranes. J Struct Biol. 2001 Jul; 135(1):47-57. PMID: 11562165.
      View in: PubMed
    119. Dessens JT, Mendoza J, Claudianos C, Vinetz JM, Khater E, Hassard S, Ranawaka GR, Sinden RE. Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes. Infect Immun. 2001 Jun; 69(6):4041-7. PMID: 11349074; PMCID: PMC98467.
    120. Sinden RE, Billingsley PF. Plasmodium invasion of mosquito cells: hawk or dove? Trends Parasitol. 2001 May; 17(5):209-12. PMID: 11323288.
      View in: PubMed
    121. Vlachou D, Lycett G, Sidén-Kiamos I, Blass C, Sinden RE, Louis C. Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes. Mol Biochem Parasitol. 2001 Feb; 112(2):229-37. PMID: 11223130.
      View in: PubMed
    122. Martínez AP, Margos G, Barker G, Sinden RE. The roles of the glycosylphosphatidylinositol anchor on the production and immunogenicity of recombinant ookinete surface antigen Pbs21 of Plasmodium berghei when prepared in a baculovirus expression system. Parasite Immunol. 2000 Oct; 22(10):493-500. PMID: 11012975.
      View in: PubMed
    123. Sidén-Kiamos I, Vlachou D, Margos G, Beetsma A, Waters AP, Sinden RE, Louis C. Distinct roles for pbs21 and pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei. J Cell Sci. 2000 Oct; 113 Pt 19:3419-26. PMID: 10984433.
      View in: PubMed
    124. del Carmen Rodriguez M, Gerold P, Dessens J, Kurtenbach K, Schwartz RT, Sinden RE, Margos G. Characterisation and expression of pbs25, a sexual and sporogonic stage specific protein of Plasmodium berghei. Mol Biochem Parasitol. 2000 Sep; 110(1):147-59. PMID: 10989152.
      View in: PubMed
    125. Dessens JT, Margos G, Rodriguez MC, Sinden RE. Identification of differentially regulated genes of Plasmodium by suppression subtractive hybridization. Parasitol Today. 2000 Aug; 16(8):354-6. PMID: 10900485.
      View in: PubMed
    126. Butcher GA, Mendoza J, Sinden RE. Inhibition of the mosquito transmission of Plasmodium berghei by Malarone (atovaquone-proguanil). Ann Trop Med Parasitol. 2000 Jul; 94(5):429-36. PMID: 10983555.
      View in: PubMed
    127. Mendis C, Jacobsen JL, Gamage-Mendis A, Bule E, Dgedge M, Thompson R, Cuamba N, Barreto J, Begtrup K, Sinden RE, Høgh B. Anopheles arabiensis and An. funestus are equally important vectors of malaria in Matola coastal suburb of Maputo, southern Mozambique. Med Vet Entomol. 2000 Jun; 14(2):171-80. PMID: 10872861.
      View in: PubMed
    128. Billker O, Miller AJ, Sinden RE. Determination of mosquito bloodmeal pH in situ by ion-selective microelectrode measurement: implications for the regulation of malarial gametogenesis. Parasitology. 2000 Jun; 120 ( Pt 6):547-51. PMID: 10874717.
      View in: PubMed
    129. Butcher GA, Sinden RE, Curtis C. Malaria: new ideas, old problems, new technologies. Parasitol Today. 2000 Feb; 16(2):43-4. PMID: 10652483.
      View in: PubMed
    130. Cook JM, Martin J, Lewin A, Sinden RE, Tristem M. Systematic screening of Anopheles mosquito genomes yields evidence for a major clade of Pao-like retrotransposons. Insect Mol Biol. 2000 Feb; 9(1):109-17. PMID: 10672078.
      View in: PubMed
    131. Enosse S, Butcher GA, Margos G, Mendoza J, Sinden RE, Høgh B. The mosquito transmission of malaria: the effects of atovaquone-proguanil (Malarone) and chloroquine. Trans R Soc Trop Med Hyg. 2000 Jan-Feb; 94(1):77-82. PMID: 10748906.
      View in: PubMed
    132. Sinden RE. Gametogenesis in Plasmodium. Bull Soc Pathol Exot. 1999 Dec; 92(5 Pt 2):437. PMID: 11000960.
      View in: PubMed
    133. Yoshida S, Matsuoka H, Luo E, Iwai K, Arai M, Sinden RE, Ishii A. A single-chain antibody fragment specific for the Plasmodium berghei ookinete protein Pbs21 confers transmission blockade in the mosquito midgut. Mol Biochem Parasitol. 1999 Nov 30; 104(2):195-204. PMID: 10593175.
      View in: PubMed
    134. Dessens JT, Beetsma AL, Dimopoulos G, Wengelnik K, Crisanti A, Kafatos FC, Sinden RE. CTRP is essential for mosquito infection by malaria ookinetes. EMBO J. 1999 Nov 15; 18(22):6221-7. PMID: 10562534; PMCID: PMC1171685.
    135. Crampton JM, Stowell SL, Karras M, Sinden RE. Model systems to evaluate the use of transgenic haematophagous insects to deliver protective vaccines. Parassitologia. 1999 Sep; 41(1-3):473-7. PMID: 10697904.
      View in: PubMed
    136. Sinden RE. Plasmodium differentiation in the mosquito. Parassitologia. 1999 Sep; 41(1-3):139-48. PMID: 10697846.
      View in: PubMed
    137. Blanco AR, Paez A, Gerold P, Dearsly AL, Margos G, Schwarz RT, Barker G, Rodriguez MC, Sinden RE. The biosynthesis and post-translational modification of Pbs21 an ookinete-surface protein of Plasmodium berghei. Mol Biochem Parasitol. 1999 Jan 25; 98(2):163-73. PMID: 10080386.
      View in: PubMed
    138. Thompson J, van Spaendonk RM, Choudhuri R, Sinden RE, Janse CJ, Waters AP. Heterogeneous ribosome populations are present in Plasmodium berghei during development in its vector. Mol Microbiol. 1999 Jan; 31(1):253-60. PMID: 9987126.
      View in: PubMed
    139. Plebanski M, Gilbert SC, Schneider J, Hannan CM, Layton G, Blanchard T, Becker M, Smith G, Butcher G, Sinden RE, Hill AV. Protection from Plasmodium berghei infection by priming and boosting T cells to a single class I-restricted epitope with recombinant carriers suitable for human use. Eur J Immunol. 1998 Dec; 28(12):4345-55. PMID: 9862371.
      View in: PubMed
    140. Margos G, van Dijk MR, Ramesar J, Janse CJ, Waters AP, Sinden RE. Transgenic expression of a mosquito-stage malarial protein, Pbs21, in blood stages of transformed Plasmodium berghei and induction of an immune response upon infection. Infect Immun. 1998 Aug; 66(8):3884-91. PMID: 9673276; PMCID: PMC108443.
    141. Schneider J, Gilbert SC, Blanchard TJ, Hanke T, Robson KJ, Hannan CM, Becker M, Sinden R, Smith GL, Hill AV. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat Med. 1998 Apr; 4(4):397-402. PMID: 9546783.
      View in: PubMed
    142. Billker O, Lindo V, Panico M, Etienne AE, Paxton T, Dell A, Rogers M, Sinden RE, Morris HR. Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito. Nature. 1998 Mar 19; 392(6673):289-92. PMID: 9521324.
      View in: PubMed
    143. Sinden RE. Malaria transfection:a new tool to study molecular function. Parasitol Today. 1998 Mar; 14(3):88-90. PMID: 17040711.
      View in: PubMed
    144. Hogh B, Gamage-Mendis A, Butcher GA, Thompson R, Begtrup K, Mendis C, Enosse SM, Dgedge M, Barreto J, Eling W, Sinden RE. The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector. Am J Trop Med Hyg. 1998 Feb; 58(2):176-82. PMID: 9502601.
      View in: PubMed
    145. Thompson R, Begtrup K, Cuamba N, Dgedge M, Mendis C, Gamage-Mendis A, Enosse SM, Barreto J, Sinden RE, Hogh B. The Matola malaria project: a temporal and spatial study of malaria transmission and disease in a suburban area of Maputo, Mozambique. Am J Trop Med Hyg. 1997 Nov; 57(5):550-9. PMID: 9392594.
      View in: PubMed
    146. Billker O, Shaw MK, Margos G, Sinden RE. The roles of temperature, pH and mosquito factors as triggers of male and female gametogenesis of Plasmodium berghei in vitro. Parasitology. 1997 Jul; 115 ( Pt 1):1-7. PMID: 9280891.
      View in: PubMed
    147. Robson KJ, Naitza S, Barker G, Sinden RE, Crisanti A. Cloning and expression of the thrombospondin related adhesive protein gene of Plasmodium berghei. Mol Biochem Parasitol. 1997 Jan; 84(1):1-12. PMID: 9041516.
      View in: PubMed
    148. Spano F, Matsuoka H, Ozawa R, Chinzei Y, Sinden RE. Epitope mapping on the ookinete surface antigen Pbs21 of Plasmodium berghei: identification of the site of binding of transmission-blocking monoclonal antibody 13.1. Parassitologia. 1996 Dec; 38(3):559-63. PMID: 9257345.
      View in: PubMed
    149. Butcher GA, Sinden RE, Billker O. Plasmodium berghei: infectivity of mice to Anopheles stephensi mosquitoes. Exp Parasitol. 1996 Dec; 84(3):371-9. PMID: 8948326.
      View in: PubMed
    150. Shaw MK, Thompson J, Sinden RE. Localization of ribosomal RNA and Pbs21-mRNA in the sexual stages of Plasmodium berghei using electron microscope in situ hybridization. Eur J Cell Biol. 1996 Nov; 71(3):270-6. PMID: 8929565.
      View in: PubMed
    151. Jones IW, Thomsen LL, Knowles R, Gutteridge WE, Butcher GA, Sinden RE. Nitric oxide synthase activity in malaria-infected mice. Parasite Immunol. 1996 Oct; 18(10):535-8. PMID: 9226691.
      View in: PubMed
    152. Allsopp CE, Plebanski M, Gilbert S, Sinden RE, Harris S, Frankel G, Dougan G, Hioe C, Nixon D, Paoletti E, Layton G, Hill AV. Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization. Eur J Immunol. 1996 Aug; 26(8):1951-9. PMID: 8765044.
      View in: PubMed
    153. Fleck SL, Pudney M, Sinden RE. The effect of atovaquone (566C80) on the maturation and viability of Plasmodium falciparum gametocytes in vitro. Trans R Soc Trop Med Hyg. 1996 May-Jun; 90(3):309-12. PMID: 8758088.
      View in: PubMed
    154. Matsuoka H, Kobayashi J, Barker GC, Miura K, Chinzei Y, Miyajima S, Ishii A, Sinden RE. Induction of anti-malarial transmission blocking immunity with a recombinant ookinete surface antigen of Plasmodium berghei produced in silkworm larvae using the baculovirus expression vector system. Vaccine. 1996 Feb; 14(2):120-6. PMID: 8852407.
      View in: PubMed
    155. Sinden RE, Butcher GA, Billker O, Fleck SL. Regulation of infectivity of Plasmodium to the mosquito vector. Adv Parasitol. 1996; 38:53-117. PMID: 8701799.
      View in: PubMed
    156. Robson KJ, Frevert U, Reckmann I, Cowan G, Beier J, Scragg IG, Takehara K, Bishop DH, Pradel G, Sinden R, et al. Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes. EMBO J. 1995 Aug 15; 14(16):3883-94. PMID: 7664729; PMCID: PMC394467.
    157. Fowler RE, Sinden RE, Pudney M. Inhibitory activity of the anti-malarial atovaquone (566C80) against ookinetes, oocysts, and sporozoites of Plasmodium berghei. J Parasitol. 1995 Jun; 81(3):452-8. PMID: 7776134.
      View in: PubMed
    158. Margos G, Kurtenbach K, Posnett E, Barker GC, Matsuoka H, Paton MG, Sinden RE. Expression of the Plasmodium berghei ookinete protein Pbs21 in a baculovirus-insect cell system produces an efficient transmission blocking immunogen. Parasite Immunol. 1995 Apr; 17(4):167-76. PMID: 7624157.
      View in: PubMed
    159. Hogh B, Thompson R, Hetzel C, Fleck SL, Kruse NA, Jones I, Dgedge M, Barreto J, Sinden RE. Specific and nonspecific responses to Plasmodium falciparum blood-stage parasites and observations on the gametocytemia in schoolchildren living in a malaria-endemic area of Mozambique. Am J Trop Med Hyg. 1995 Jan; 52(1):50-9. PMID: 7856825.
      View in: PubMed
    160. Thompson J, Sinden RE. In situ detection of Pbs21 mRNA during sexual development of Plasmodium berghei. Mol Biochem Parasitol. 1994 Dec; 68(2):189-96. PMID: 7739665.
      View in: PubMed
    161. Ranawaka GR, Fleck SL, Blanco AR, Sinden RE. Characterization of the modes of action of anti-Pbs21 malaria transmission-blocking immunity: ookinete to oocyst differentiation in vivo. Parasitology. 1994 Nov; 109 ( Pt 4):403-11. PMID: 7800408.
      View in: PubMed
    162. Billingsley PF, Medley GF, Charlwood D, Sinden RE. Relationship between prevalence and intensity of Plasmodium falciparum infection in natural populations of Anopheles mosquitoes. Am J Trop Med Hyg. 1994 Sep; 51(3):260-70. PMID: 7943543.
      View in: PubMed
    163. Jones IW, Denholm AA, Ley SV, Lovell H, Wood A, Sinden RE. Sexual development of malaria parasites is inhibited in vitro by the neem extract azadirachtin, and its semi-synthetic analogues. FEMS Microbiol Lett. 1994 Jul 15; 120(3):267-73. PMID: 7980823.
      View in: PubMed
    164. Ranawaka GR, Alejo-Blanco AR, Sinden RE. Characterization of the effector mechanisms of a transmission-blocking antibody upon differentiation of Plasmodium berghei gametocytes into ookinetes in vitro. Parasitology. 1994 Jul; 109 ( Pt 1):11-7. PMID: 8058360.
      View in: PubMed
    165. Kumar S, van Pelt JF, O'Dowd CA, Hollingdale MR, Sinden RE. Effects of hormones and cysteine protease modulators on infection of HepG2 cells by Plasmodium berghei sporozoites in vitro determined by ELISA immunoassay. J Parasitol. 1994 Jun; 80(3):414-20. PMID: 8195943.
      View in: PubMed
    166. Fowler RE, Billingsley PF, Pudney M, Sinden RE. Inhibitory action of the anti-malarial compound atovaquone (566C80) against Plasmodium berghei ANKA in the mosquito, Anopheles stephensi. Parasitology. 1994 May; 108 ( Pt 4):383-8. PMID: 8008451.
      View in: PubMed
    167. Fleck SL, Butcher GA, Sinden RE. Plasmodium berghei: serum-mediated inhibition of infectivity of infected mice to Anopheles stephensi mosquitoes. Exp Parasitol. 1994 Feb; 78(1):20-7. PMID: 8299757.
      View in: PubMed
    168. Matsuoka H, Paton MG, Barker GC, Alejo Blanco AR, Sinden RE. Studies on the immunogenicity of a recombinant ookinete surface antigen Pbs21 from Plasmodium berghei expressed in Escherichia coli. Parasite Immunol. 1994 Jan; 16(1):27-34. PMID: 8152832.
      View in: PubMed
    169. Barker GC, Rodríguez MH, Sinden RE. Attempted isolation of the gene encoding the 21 Kd Plasmodium berghei ookinete transmission blocking antigen from Plasmodium yoelli and Plasmodium vivax. Mem Inst Oswaldo Cruz. 1994; 89 Suppl 2:37-41. PMID: 7565129.
      View in: PubMed
    170. Janse CJ, Ponzi M, Sinden RE, Waters AP. Chromosomes and sexual development of rodent malaria parasites. Mem Inst Oswaldo Cruz. 1994; 89 Suppl 2:43-6. PMID: 7565130.
      View in: PubMed
    171. Butcher GA, Couchman AF, Van Pelt JF, Fleck SL, Sinden RE. The SCID mouse as a laboratory model for development of the exoerythrocytic stages of human and rodent malaria. Exp Parasitol. 1993 Sep; 77(2):257-60. PMID: 8375494.
      View in: PubMed
    172. Simonetti AB, Billingsley PF, Winger LA, Sinden RE. Kinetics of expression of two major Plasmodium berghei antigens in the mosquito vector, Anopheles stephensi. J Eukaryot Microbiol. 1993 Sep-Oct; 40(5):569-76. PMID: 8401470.
      View in: PubMed
    173. Ranawaka G, Alejo-Blanco R, Sinden RE. The effect of transmission-blocking antibody ingested in primary and secondary bloodfeeds, upon the development of Plasmodium berghei in the mosquito vector. Parasitology. 1993 Sep; 107 ( Pt 3):225-31. PMID: 8233585.
      View in: PubMed
    174. Sinden RE, Barker GC, Paton MJ, Fleck SL, Butcher GA, Waters A, Janse CJ, Rodriguez MH. Factors regulating natural transmission of Plasmodium berghei to the mosquito vector, and the cloning of a transmission-blocking immunogen. Parassitologia. 1993 Jul; 35 Suppl:107-12. PMID: 7694225.
      View in: PubMed
    175. Müller HM, Crampton JM, della Torre A, Sinden R, Crisanti A. Members of a trypsin gene family in Anopheles gambiae are induced in the gut by blood meal. EMBO J. 1993 Jul; 12(7):2891-900. PMID: 8335004; PMCID: PMC413542.
    176. Paton MG, Barker GC, Matsuoka H, Ramesar J, Janse CJ, Waters AP, Sinden RE. Structure and expression of a post-transcriptionally regulated malaria gene encoding a surface protein from the sexual stages of Plasmodium berghei. Mol Biochem Parasitol. 1993 Jun; 59(2):263-75. PMID: 8341324.
      View in: PubMed
    177. Medley GF, Sinden RE, Fleck S, Billingsley PF, Tirawanchai N, Rodriguez MH. Heterogeneity in patterns of malarial oocyst infections in the mosquito vector. Parasitology. 1993 Jun; 106 ( Pt 5):441-9. PMID: 8341579.
      View in: PubMed
    178. Hollingdale MR, Sinden RE, van Pelt J. Sporozoite invasion. Nature. 1993 Mar 04; 362(6415):26. PMID: 8446167.
      View in: PubMed
    179. Suhrbier A, Sinden RE, Couchman A, Fleck SL, Kumar S, McMillan D. Immunological detection of cytoskeletal proteins in the exoerythrocytic stages of malaria by fluorescence and confocal laser scanning microscopy. J Eukaryot Microbiol. 1993 Jan-Feb; 40(1):18-23. PMID: 8457799.
      View in: PubMed
    180. Sinden RE. Antimalarial transmission-blocking vaccines. Sci Prog. 1993-1994; 77 ( Pt 1-2):1-14. PMID: 7801089.
      View in: PubMed
    181. Davies CS, Pudney M, Nicholas JC, Sinden RE. The novel hydroxynaphthoquinone 566C80 inhibits the development of liver stages of Plasmodium berghei cultured in vitro. Parasitology. 1993 Jan; 106 ( Pt 1):1-6. PMID: 8479795.
      View in: PubMed
    182. Kawamoto Y, Winger LA, Hong K, Matsuoka H, Chinzei Y, Kawamoto F, Kamimura K, Arakawa R, Sinden RE, Miyama A. Plasmodium berghei: sporozoites are sensitive to human serum but not susceptible host serum. Exp Parasitol. 1992 Nov; 75(3):361-8. PMID: 1426138.
      View in: PubMed
    183. Winger LA, Sinden RE. Immunoprotection in mice susceptible to waning memory against the pre-erythrocytic stages of malaria after validated immunisation with irradiated sporozoites of Plasmodium berghei. Parasitol Res. 1992; 78(5):427-32. PMID: 1495922.
      View in: PubMed
    184. Kawamoto F, Kido N, Hanaichi T, Djamgoz MB, Sinden RE. Gamete development in Plasmodium berghei regulated by ionic exchange mechanisms. Parasitol Res. 1992; 78(4):277-84. PMID: 1329079.
      View in: PubMed
    185. Sinden RE. Asexual blood stages of malaria modulate gametocyte infectivity to the mosquito vector--possible implications for control strategies. Parasitology. 1991 Oct; 103 Pt 2:191-6. PMID: 1684037.
      View in: PubMed
    186. Sinden RE, Couchman A, Suhrbier A, Marsh F, Winger L, Ranawaka G. The development of exo-erythrocytic schizonts of Plasmodium berghei in vitro from gamma-irradiated and non-irradiated sporozoites: a study using confocal laser scanning microscopy. Parasitology. 1991 Aug; 103 Pt 1:17-21. PMID: 1658716.
      View in: PubMed
    187. Billingsley PF, Hodivala KJ, Winger LA, Sinden RE. Detection of mature malaria infections in live mosquitoes. Trans R Soc Trop Med Hyg. 1991 Jul-Aug; 85(4):450-3. PMID: 1755048.
      View in: PubMed
    188. Sinden RE. Mitosis and meiosis in malarial parasites. Acta Leiden. 1991; 60(1):19-27. PMID: 1820709.
      View in: PubMed
    189. Kawamoto F, Alejo-Blanco R, Fleck SL, Sinden RE. Plasmodium berghei: ionic regulation and the induction of gametogenesis. Exp Parasitol. 1991 Jan; 72(1):33-42. PMID: 1993463.
      View in: PubMed
    190. Tirawanchai N, Winger LA, Nicholas J, Sinden RE. Analysis of immunity induced by the affinity-purified 21-kilodalton zygote-ookinete surface antigen of Plasmodium berghei. Infect Immun. 1991 Jan; 59(1):36-44. PMID: 1987051; PMCID: PMC257702.
    191. Suhrbier A, Raynes JG, Walby MI, McAdam KP, Sinden RE. C-reactive protein and the liver stage of Plasmodium vivax and P. berghei. Trans R Soc Trop Med Hyg. 1990 Nov-Dec; 84(6):781. PMID: 2096504.
      View in: PubMed
    192. Suhrbier A, Winger L, O'Dowd C, Hodivala K, Sinden RE. An antigen specific to the liver stage of rodent malaria recognized by a monoclonal antibody. Parasite Immunol. 1990 Sep; 12(5):473-81. PMID: 2255559.
      View in: PubMed
    193. Suhrbier A, Winger LA, Castellano E, Sinden RE. Survival and antigenic profile of irradiated malarial sporozoites in infected liver cells. Infect Immun. 1990 Sep; 58(9):2834-9. PMID: 1974886; PMCID: PMC313575.
    194. Kawamoto F, Alejo-Blanco R, Fleck SL, Kawamoto Y, Sinden RE. Possible roles of Ca2+ and cGMP as mediators of the exflagellation of Plasmodium berghei and Plasmodium falciparum. Mol Biochem Parasitol. 1990 Aug; 42(1):101-8. PMID: 2172816.
      View in: PubMed
    195. Tirawanchai N, Sinden RE. Three non-repeated transmission blocking epitopes recognized in the 21 kD surface antigen of zygotes-ookinetes of Plasmodium berghei. Parasite Immunol. 1990 Jul; 12(4):435-46. PMID: 1698275.
      View in: PubMed
    196. Dearsly AL, Sinden RE, Self IA. Sexual development in malarial parasites: gametocyte production, fertility and infectivity to the mosquito vector. Parasitology. 1990 Jun; 100 Pt 3:359-68. PMID: 2194152.
      View in: PubMed
    197. Lockyer MJ, Davies CS, Suhrbier A, Sinden RE. Nucleotide sequence of the Plasmodium berghei circumsporozoite protein gene from the ANKA clone 2.34L. Nucleic Acids Res. 1990 Jan 25; 18(2):376. PMID: 2183186; PMCID: PMC330291.
    198. Sinden RE, Suhrbier A, Davies CS, Fleck SL, Hodivala K, Nicholas JC. The development and routine application of high-density exoerythrocytic-stage cultures of Plasmodium berghei. Bull World Health Organ. 1990; 68 Suppl:115-25. PMID: 2094577; PMCID: PMC2393025.
    199. Mons B, Sinden RE. Laboratory models for research in vivo and in vitro on malaria parasites of mammals: Current status. Parasitol Today. 1990 Jan; 6(1):3-7. PMID: 15463241.
      View in: PubMed
    200. Winger L, Suhrbier A, O'Dowd CA, Hodivala KJ, Sinden RE. A liver-stage specific antigen of P. berghei identified by a monoclonal antibody. Bull World Health Organ. 1990; 68 Suppl:172-7. PMID: 2094583; PMCID: PMC2393036.
    201. Sinden RE, Bray RS, Hartley R, Suhrbier A, Jiang JB, Krotoski WA, Gwadz RW. An ultrastructural study of the exoerythrocytic schizonts of Plasmodium cynomolgi and P. knowlesi in Macaca mulatta. Acta Trop. 1990 Jan; 47(1):11-21. PMID: 1967505.
      View in: PubMed
    202. Suhrbier A, Wiser MF, Winger L, Harte P, Newton MF, Hodivala KJ, Nicholas J, Sinden RE. Contrasts in antigen expression in the erythrocytic and exoerythrocytic stages of rodent malaria. Parasitology. 1989 Oct; 99 Pt 2:165-70. PMID: 2687775.
      View in: PubMed
    203. Suhrbier A, Holder AA, Wiser MF, Nicholas J, Sinden RE. Expression of the precursor of the major merozoite surface antigens during the hepatic stage of malaria. Am J Trop Med Hyg. 1989 Apr; 40(4):351-5. PMID: 2469336.
      View in: PubMed
    204. Davies CS, Suhrbier AS, Winger LA, Sinden RE. Improved techniques for the culture of the liver stages of Plasmodium berghei and their relevance to the study of causal prophylactic drugs. Acta Leiden. 1989; 58(2):97-113. PMID: 2489396.
      View in: PubMed
    205. Sinden RE. Recent advances in the parasitology of malaria. Trans R Soc Trop Med Hyg. 1989; 83 Suppl:3-9. PMID: 2696157.
      View in: PubMed
    206. Davies CS, Pudney M, Matthews PJ, Sinden RE. The causal prophylactic activity of the novel hydroxynaphthoquinone 566C80 against Plasmodium berghei infections in rats. Acta Leiden. 1989; 58(2):115-28. PMID: 2489391.
      View in: PubMed
    207. Sinden RE. Variation and polymorphism in parasite phenotype--implications for the selection of potential intervention strategies. Parasitology. 1989; 99 Suppl:S147-51. PMID: 2682482.
      View in: PubMed
    208. Hamilton AJ, Davies CS, Sinden RE. Expression of circumsporozoite proteins revealed in situ in the mosquito stages of Plasmodium berghei by the Lowicryl-immunogold technique. Parasitology. 1988 Apr; 96 ( Pt 2):273-80. PMID: 3287283.
      View in: PubMed
    209. Suhrbier A, Hamilton AJ, Nicholas J, Sinden RE. The fate of the circumsporozoite antigens during the exoerythrocytic stage of Plasmodium berghei. Eur J Cell Biol. 1988 Apr; 46(1):25-30. PMID: 3294008.
      View in: PubMed
    210. Winger LA, Tirawanchai N, Nicholas J, Carter HE, Smith JE, Sinden RE. Ookinete antigens of Plasmodium berghei. Appearance on the zygote surface of an Mr 21 kD determinant identified by transmission-blocking monoclonal antibodies. Parasite Immunol. 1988 Mar; 10(2):193-207. PMID: 2453831.
      View in: PubMed
    211. Hamilton AJ, Suhrbier A, Nicholas J, Sinden RE. Immunoelectron microscopic localization of circumsporozoite antigen in the differentiating exoerythrocytic trophozoite of Plasmodium berghei. Cell Biol Int Rep. 1988 Feb; 12(2):123-9. PMID: 3293804.
      View in: PubMed
    212. Sinden RE. Progress in in-vitro culture of the malaria life cycle. Parasitol Today. 1987 Oct; 3(10):292. PMID: 15462870.
      View in: PubMed
    213. Dearsly AL, Nicholas J, Sinden RE. Sexual development in Plasmodium berghei: the use of mitomycin C to separate infective gametocytes in vivo and ookinetes in vitro. Int J Parasitol. 1987 Oct; 17(7):1307-12. PMID: 3123410.
      View in: PubMed
    214. Carter EH, Suhrbier A, Beckers PJ, Sinden RE. The in vitro cultivation of P. falciparum ookinetes, and their enrichment on Nycodenz density gradients. Parasitology. 1987 Aug; 95 ( Pt 1):25-30. PMID: 3313206.
      View in: PubMed
    215. Sinden RE, Winger L, Carter EH, Hartley RH, Tirawanchai N, Davies CS, Moore J, Sluiters JF. Ookinete antigens of Plasmodium berghei: a light and electron-microscope immunogold study of expression of the 21 kDa determinant recognized by a transmission-blocking antibody. Proc R Soc Lond B Biol Sci. 1987 May 22; 230(1261):443-58. PMID: 2440053.
      View in: PubMed
    216. Suhrbier A, Janse C, Mons B, Fleck SL, Nicholas J, Davies CS, Sinden RE. The complete development in vitro of the vertebrate phase of the mammalian malarial parasite Plasmodium berghei. Trans R Soc Trop Med Hyg. 1987; 81(6):907-9. PMID: 3332508.
      View in: PubMed
    217. Suhrbier A, Davies CS, Sinden RE. Intranuclear development of Plasmodium berghei in liver cells. Cell Biol Int Rep. 1986 Dec; 10(12):994. PMID: 3542241.
      View in: PubMed
    218. Krotoski WA, Garnham PC, Cogswell FB, Collins WE, Bray RS, Gwasz RW, Killick-Kendrick R, Wolf RH, Sinden R, Hollingdale M, et al. Observations on early and late post-sporozoite tissue stages in primate malaria. IV. Pre-erythrocytic schizonts and/or hypnozoites of Chesson and North Korean strains of Plasmodium vivax in the chimpanzee. Am J Trop Med Hyg. 1986 Mar; 35(2):263-74. PMID: 3513645.
      View in: PubMed
    219. Meis JF, Rijntjes PJ, Verhave JP, Ponnudurai T, Hollingdale MR, Smith JE, Sinden RE, Jap PH, Meuwissen JH, Yap SH. Fine structure of the malaria parasite Plasmodium falciparum in human hepatocytes in vitro. Cell Tissue Res. 1986; 244(2):345-50. PMID: 3521880.
      View in: PubMed
    220. Targett GA, Sinden RE. Transmission blocking vaccines. Parasitol Today. 1985 Dec; 1(6):155-8. PMID: 15275571.
      View in: PubMed
    221. Sinden RE, Hartley RH. Identification of the meiotic division of malarial parasites. J Protozool. 1985 Nov; 32(4):742-4. PMID: 3906103.
      View in: PubMed
    222. Sinden RE, Hartley RH, Winger L. The development of Plasmodium ookinetes in vitro: an ultrastructural study including a description of meiotic division. Parasitology. 1985 Oct; 91 ( Pt 2):227-44. PMID: 3906519.
      View in: PubMed
    223. Sinden RE, Hartley RH, King NJ. Gametogenesis in Plasmodium; the inhibitory effects of anticytoskeletal agents. Int J Parasitol. 1985 Apr; 15(2):211-7. PMID: 4039709.
      View in: PubMed
    224. Bray RS, Krotoski WA, Cogswell FB, Garnham PC, Rodriguez M, Guy MW, Gwadz RW, Sinden RE, Targett GA, Draper CC, et al. Observations on early and late post-sporozoite tissue stages in primate malaria. III. Further attempts to find early forms and to correlate hypnozoites with growing exo-erythrocytic schizonts and parasitaemic relapses in Plasmodium cynomolgi bastianellii infections. Trans R Soc Trop Med Hyg. 1985; 79(2):269-73. PMID: 4002302.
      View in: PubMed
    225. Sinden RE. Gametocytogenesis in Plasmodium spp., and observations on the meiotic division. Ann Soc Belg Med Trop. 1985; 65 Suppl 2:21-33. PMID: 4073978.
      View in: PubMed
    226. Sinden RE. A cell biologist's view of host cell recognition and invasion by malarial parasites. Trans R Soc Trop Med Hyg. 1985; 79(5):598-605. PMID: 3913067.
      View in: PubMed
    227. Sinden RE. The biology of Plasmodium in the mosquito. Experientia. 1984 Dec 15; 40(12):1330-43. PMID: 6150864.
      View in: PubMed
    228. Sinden RE, Ponnudurai T, Smits MA, Simm AM, Meuwissen JH. Gametocytogenesis of Plasmodium falciparum in vitro: a simple technique for the routine culture of pure capacitated gametocytes en masse. Parasitology. 1984 Apr; 88 ( Pt 2):239-47. PMID: 6371671.
      View in: PubMed
    229. Smith JE, Pirson P, Sinden RE. Studies on the kinetics of uptake and distribution of free and liposome-entrapped primaquine, and of sporozoites by isolated perfused rat liver. Ann Trop Med Parasitol. 1983 Aug; 77(4):379-86. PMID: 6639183.
      View in: PubMed
    230. Meis JF, Verhave JP, Jap PH, Sinden RE, Meuwissen JH. Ultrastructural observations on the infection of rat liver by Plasmodium berghei sporozoites in vivo. J Protozool. 1983 May; 30(2):361-6. PMID: 6355454.
      View in: PubMed
    231. Sinden RE. The cell biology of sexual development in plasmodium. Parasitology. 1983 Apr; 86 (Pt 4):7-28. PMID: 6191269.
      View in: PubMed
    232. Meis JF, Verhave JP, Jap PH, Sinden RE, Meuwissen JH. Malaria parasites--discovery of the early liver form. Nature. 1983 Mar 31-Apr 6; 302(5907):424-6. PMID: 6339945.
      View in: PubMed
    233. Sinden RE. Sexual development of malarial parasites. Adv Parasitol. 1983; 22:153-216. PMID: 6141715.
      View in: PubMed
    234. Krotoski WA, Collins WE, Bray RS, Garnham PC, Cogswell FB, Gwadz RW, Killick-Kendrick R, Wolf R, Sinden R, Koontz LC, Stanfill PS. Demonstration of hypnozoites in sporozoite-transmitted Plasmodium vivax infection. Am J Trop Med Hyg. 1982 Nov; 31(6):1291-3. PMID: 6816080.
      View in: PubMed
    235. Russell DG, Sinden RE. Three-dimensional study of the intact cytoskeleton of coccidian sporozoites. Int J Parasitol. 1982 Jun; 12(2-3):221-6. PMID: 7076393.
      View in: PubMed
    236. Bannister LH, Sinden RE. New knowledge of parasite morphology. Br Med Bull. 1982 May; 38(2):141-5. PMID: 7052194.
      View in: PubMed
    237. Sinden RE. Gametocytogenesis of Plasmodium falciparum in vitro: an electron microscopic study. Parasitology. 1982 Feb; 84(1):1-11. PMID: 7038594.
      View in: PubMed
    238. Sinden RE. Gametocytogenesis of Plasmodium falciparum in vitro: ultrastructural observations on the lethal action of chloroquine. Ann Trop Med Parasitol. 1982 Feb; 76(1):15-23. PMID: 7044323.
      View in: PubMed
    239. Smith JE, Sinden RE. Studies on the role of host serum in the retention of malarial sporozoites by isolated perfused rat liver. Trans R Soc Trop Med Hyg. 1982; 76(1):45-7. PMID: 7080155.
      View in: PubMed
    240. Knight A, Sinden RE. The purification of gametocytes of Plasmodium falciparum and P. yoelii nigeriensis by colloidal silica (Percoll) gradient centrifugation. Trans R Soc Trop Med Hyg. 1982; 76(4):503-9. PMID: 6763789.
      View in: PubMed
    241. Russell DG, Sinden RE. The role of the cytoskeleton in the motility of coccidian sporozoites. J Cell Sci. 1981 Aug; 50:345-59. PMID: 7033252.
      View in: PubMed
    242. Sinden RE. Sexual development of malarial parasites in their mosquito vectors. Trans R Soc Trop Med Hyg. 1981; 75(1):171-2. PMID: 6115489.
      View in: PubMed
    243. Sinden RE, Smith J. Culture of the liver stages (exoerythrocytic schizonts) of rodent malaria parasites from sporozoites in vitro. Trans R Soc Trop Med Hyg. 1980; 74(1):134-6. PMID: 7001683.
      View in: PubMed
    244. Sinden RE, Smalley ME. Gametocytogenesis of Plasmodium falciparum in vitro: the cell-cycle. Parasitology. 1979 Oct; 79(2):277-96. PMID: 395486.
      View in: PubMed
    245. Garnham PC, Duggan AJ, Sinden RE. A new species of Sarcocystis in the brain of two exotic birds. Ann Parasitol Hum Comp. 1979 Jul-Aug; 54(4):393-400. PMID: 119465.
      View in: PubMed
    246. Bray RS, Sinden RE. The sequestration of Plasmodium falciparum infected erythrocytes in the placenta. Trans R Soc Trop Med Hyg. 1979; 73(6):716-9. PMID: 395729.
      View in: PubMed
    247. Sinden RE, Canning EU, Bray RS, Smalley ME. Gametocyte and gamete development in Plasmodium falciparum. Proc R Soc Lond B Biol Sci. 1978 Jun 05; 201(1145):375-99. PMID: 27809.
      View in: PubMed
    248. Sinden RE, Strong K. An ultrastructural study of the sporogonic development of Plasmodium falciparum in Anopheles gambiae. Trans R Soc Trop Med Hyg. 1978; 72(5):477-91. PMID: 364785.
      View in: PubMed
    249. Toyé PJ, Sinden RE, Canning EU. The action of metabolic inhibitors on microgametogenesis in Plasmodium yoelii nigeriensis. Z Parasitenkd. 1977 Sep 21; 53(2):133-41. PMID: 919692.
      View in: PubMed
    250. Smalley ME, Sinden RE. Plasmodium falciparum gametocytes: their longevity and infectivity. Parasitology. 1977 Feb; 74(1):1-8. PMID: 320542.
      View in: PubMed
    251. Canning EU, Sinden RE, Landau I, Miltgen F. Ultrastructural observations on the merocyst and gametocytes of Hepatocystis spp. from Malaysian squirrels. Ann Parasitol Hum Comp. 1976 Nov-Dec; 51(6):607-23. PMID: 829210.
      View in: PubMed
    252. Sinden RE, Canning EU, Spain B. Gametogenesis and fertilization in Plasmodium yoelii nigeriensis: a transmission electron microscope study. Proc R Soc Lond B Biol Sci. 1976 Mar 30; 193(1110):55-76. PMID: 4810.
      View in: PubMed
    253. Sinden RE, Smalley ME. Gametocytes of Plasmodium falciparum: phagocytosis by leucocytes in vivo and in vitro. Trans R Soc Trop Med Hyg. 1976; 70(4):344-5. PMID: 795106.
      View in: PubMed
    254. Canning EU, Sinden RE. Nuclear organisation in gametocytes of Plasmodium and Hepatocystis: a cytochemical study. Z Parasitenkd. 1975 Jul 16; 46(4):297-9. PMID: 812282.
      View in: PubMed
    255. Sinden RE, Croll NA. Cytology and kinetics of microgametogenesis and fertilization in Plasmodium yoelii nigeriensis. Parasitology. 1975 Feb; 70(1):53-65. PMID: 1118188.
      View in: PubMed
    256. Killich-Kendrick R, Sinden RE, Leaney AJ. Proceedings: Scanning electron microscopy of Leishmania from midguts of experimentally infected sandflies. Trans R Soc Trop Med Hyg. 1975; 69(4):432. PMID: 1216308.
      View in: PubMed
    257. Southwood TR, Khalaf S, Sinden RE. The micro-organisms of tsetse flies. Acta Trop. 1975; 32(3):259-66. PMID: 1986.
      View in: PubMed
    258. Sinden RE. Excystment by sporozoites of malaria parasites. Nature. 1974 Nov 22; 252(5481):314. PMID: 4431453.
      View in: PubMed
    259. Moore J, Sinden RE. Fine structure of Plasmodium mexicanum. J Parasitol. 1974 Oct; 60(5):825-34. PMID: 4430950.
      View in: PubMed
    260. Sinden RE, Moore J. Fine structure of the sporozoite of Schellackia occidentalis. J Parasitol. 1974 Aug; 60(4):666-73. PMID: 4212016.
      View in: PubMed
    261. Canning EU, Sinden RE. The organization of the ookinete and observations on nuclear division in oocysts of Plasmodium berghei. Parasitology. 1973 Aug; 67(1):29-40. PMID: 4579580.
      View in: PubMed
    262. Sinden RE. The synthesis of the immobilization antigen in Paramecium aurelia: in vitro localization of antigen in ribosomal cell fractions. J Protozool. 1973 May; 20(2):307-15. PMID: 4122737.
      View in: PubMed
    263. Moore J, Sinden RE, Garnham PC. The fine structure of Plasmodium mexicanum. Trans R Soc Trop Med Hyg. 1973; 67(1):13-4. PMID: 4777396.
      View in: PubMed
    264. Sinden RE, Garnham PC. A comparative study on the ultrastructure of Plasmodium sporozoites within the oöcyst and salivary glands, with particular reference to the incidence of the micropore. Trans R Soc Trop Med Hyg. 1973; 67(5):631-7. PMID: 4591782.
      View in: PubMed
    265. Sinden RE, Canning EU. The ultrastructure of Plasmodium berghei oökinetes in the midgut wall of Anopheles stephensi. Trans R Soc Trop Med Hyg. 1972; 66(1):6. PMID: 5065468.
      View in: PubMed
    266. Sinden RE. The synthesis of the immobilization antigens in Paramecium aurelia: in situ localization of immobilization antigen using fluorescein- or ferritin-conjugated antibodies. J Microsc. 1971 Apr; 93(2):129-44. PMID: 4999940.
      View in: PubMed
    267. Sinden RE. Identification of specific antibodies prepared against purified immobilization antigens of Paramecium aurelia. J Protozool. 1970 Nov; 17(4):600-3. PMID: 4101136.
      View in: PubMed
    268. Sommerville J, Sinden R. Protein synthesis by free and bound Paramecium ribosomes in vivo and in vitro. J Protozool. 1968 Nov; 15(4):644-51. PMID: 5719061.
      View in: PubMed
    269. Caspary EA, Sinden RE, Field EJ. Some observations on the role of circulating antibody in protection against experimental allergic encephalomyelitis. Z Immunitatsforsch Allerg Klin Immunol. 1966 Jun; 130(5):454-60. PMID: 4228969.
      View in: PubMed
    270. SINDEN RE. Note on MacAdam's determination of chromaticity sensibilities. J Opt Soc Am. 1945 Nov; 35:737-42. PMID: 21004348.
      View in: PubMed
    Sinden's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description