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Professor Donald Harn

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tundup S, Srivastava L, Norberg T, Watford W, Harn D. A Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway. PLoS One. 2015; 10(9):e0137495. PMID: 26340260; PMCID: PMC4560409.
    2. Krishna S, Keralapurath MM, Lin Z, Wagner JJ, de La Serre CB, Harn DA, Filipov NM. Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice. Neuroscience. 2015 Jun 25; 297:170-81. PMID: 25849614.
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    3. Gordon CA, Acosta LP, Gobert GN, Jiz M, Olveda RM, Ross AG, Gray DJ, Williams GM, Harn D, Li Y, McManus DP. High prevalence of Schistosoma japonicum and Fasciola gigantica in bovines from Northern Samar, the Philippines. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003108. PMID: 25643317; PMCID: PMC4313937.
    4. Gordon CA, Acosta LP, Gobert GN, Olveda RM, Ross AG, Williams GM, Gray DJ, Harn D, Li Y, McManus DP. Real-time PCR demonstrates high prevalence of Schistosoma japonicum in the Philippines: implications for surveillance and control. PLoS Negl Trop Dis. 2015 Jan; 9(1):e0003483. PMID: 25606851; PMCID: PMC4301913.
    5. Grenfell RF, Shollenberger LM, Samli EF, Harn DA. Vaccine self-assembling immune matrix is a new delivery platform that enhances immune responses to recombinant HBsAg in mice. Clin Vaccine Immunol. 2015 Mar; 22(3):336-43. PMID: 25609075; PMCID: PMC4340892.
    6. Marrache S, Tundup S, Harn DA, Dhar S. Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells. Methods Mol Biol. 2015; 1265:113-22. PMID: 25634271.
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    7. Bui CT, Shollenberger LM, Paterson Y, Harn DA. Schistosoma mansoni soluble egg antigens enhance T cell responses to a newly identified HIV-1 Gag H-2b epitope. Clin Vaccine Immunol. 2015 Feb; 22(2):193-9. PMID: 25520148; PMCID: PMC4308864.
    8. Inobaya MT, Olveda RM, Tallo V, McManus DP, Williams GM, Harn DA, Li Y, Chau TN, Olveda DU, Ross AG. Schistosomiasis mass drug administration in the Philippines: lessons learnt and the global implications. Microbes Infect. 2015 Jan; 17(1):6-15. PMID: 25448635.
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    9. Olveda DU, Olveda RM, McManus DP, Cai P, Chau TN, Lam AK, Li Y, Harn DA, Vinluan ML, Ross AG. The chronic enteropathogenic disease schistosomiasis. Int J Infect Dis. 2014 Nov; 28:193-203. PMID: 25250908.
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    10. Ross AG, Olveda RM, Chy D, Olveda DU, Li Y, Harn DA, Gray DJ, McManus DP, Tallo V, Chau TN, Williams GM. Can mass drug administration lead to the sustainable control of schistosomiasis? J Infect Dis. 2015 Jan 15; 211(2):283-9. PMID: 25070942.
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    11. Bui CT, Shollenberger LM, Paterson Y, Harn DA. Schistosoma mansoni soluble egg antigens enhance Listeria monocytogenes vector HIV-1 vaccine induction of cytotoxic T cells. Clin Vaccine Immunol. 2014 Sep; 21(9):1232-9. PMID: 24990901; PMCID: PMC4178565.
    12. Gray DJ, Li YS, Williams GM, Zhao ZY, Harn DA, Li SM, Ren MY, Feng Z, Guo FY, Guo JG, Zhou J, Dong YL, Li Y, Ross AG, McManus DP. A multi-component integrated approach for the elimination of schistosomiasis in the People's Republic of China: design and baseline results of a 4-year cluster-randomised intervention trial. Int J Parasitol. 2014 Aug; 44(9):659-68. PMID: 24929133.
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    13. Tundup S, Srivastava L, Nagy T, Harn D. CD14 influences host immune responses and alternative activation of macrophages during Schistosoma mansoni infection. Infect Immun. 2014 Aug; 82(8):3240-51. PMID: 24866794; PMCID: PMC4136223.
    14. Pathak RK, Marrache S, Harn DA, Dhar S. Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate. ACS Chem Biol. 2014 May 16; 9(5):1178-87. PMID: 24617941; PMCID: PMC4033660.
    15. Srivastava L, Tundup S, Choi BS, Norberg T, Harn D. Immunomodulatory glycan lacto-N-fucopentaose III requires clathrin-mediated endocytosis to induce alternative activation of antigen-presenting cells. Infect Immun. 2014 May; 82(5):1891-903. PMID: 24566617; PMCID: PMC3993454.
    16. Grenfell RF, Coelho PM, Taboada D, de Mattos AC, Davis R, Harn DA. Newly established monoclonal antibody diagnostic assays for Schistosoma mansoni direct detection in areas of low endemicity. PLoS One. 2014; 9(1):e87777. PMID: 24498191; PMCID: PMC3909226.
    17. Li YS, McManus DP, Lin DD, Williams GM, Harn DA, Ross AG, Feng Z, Gray DJ. The Schistosoma japonicum self-cure phenomenon in water buffaloes: potential impact on the control and elimination of schistosomiasis in China. Int J Parasitol. 2014 Mar; 44(3-4):167-71. PMID: 24440417.
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    18. Olveda DU, Li Y, Olveda RM, Lam AK, McManus DP, Chau TN, Harn DA, Williams GM, Gray DJ, Ross AG. Bilharzia in the Philippines: past, present, and future. Int J Infect Dis. 2014 Jan; 18:52-6. PMID: 24211228.
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    19. Shollenberger LM, Bui CT, Paterson Y, Nyhoff L, Harn DA. HIV-1 vaccine-specific responses induced by Listeria vector vaccines are maintained in mice subsequently infected with a model helminth parasite, Schistosoma mansoni. Vaccine. 2013 Nov 19; 31(48):5651-8. PMID: 24120546.
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    20. Ross AG, Olveda RM, Acosta L, Harn DA, Chy D, Li Y, Gray DJ, Gordon CA, McManus DP, Williams GM. Road to the elimination of schistosomiasis from Asia: the journey is far from over. Microbes Infect. 2013 Nov; 15(13):858-65. PMID: 23973709; PMCID: PMC4433715.
    21. Marrache S, Tundup S, Harn DA, Dhar S. Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy. ACS Nano. 2013 Aug 27; 7(8):7392-402. PMID: 23899410.
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    22. Shollenberger LM, Bui C, Paterson Y, Allen K, Harn D. Successful vaccination of immune suppressed recipients using Listeria vector HIV-1 vaccines in helminth infected mice. Vaccine. 2013 Apr 12; 31(16):2050-6. PMID: 23470236.
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    23. Grenfell R, Harn DA, Tundup S, Da'dara A, Siqueira L, Coelho PM. New approaches with different types of circulating cathodic antigen for the diagnosis of patients with low Schistosoma mansoni load. PLoS Negl Trop Dis. 2013; 7(2):e2054. PMID: 23469295; PMCID: PMC3585039.
    24. Marrache S, Choi JH, Tundup S, Zaver D, Harn DA, Dhar S. Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer. Integr Biol (Camb). 2013 Jan; 5(1):215-23. PMID: 22832596; PMCID: PMC3524336.
    25. Bhargava P, Li C, Stanya KJ, Jacobi D, Dai L, Liu S, Gangl MR, Harn DA, Lee CH. Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways. Nat Med. 2012 Nov; 18(11):1665-72. PMID: 23104131; PMCID: PMC3493877.
    26. Tundup S, Srivastava L, Harn DA. Polarization of host immune responses by helminth-expressed glycans. Ann N Y Acad Sci. 2012 Apr; 1253:E1-E13. PMID: 22974465.
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    27. Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I. Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis. Clin Immunol. 2012 Mar; 142(3):351-61. PMID: 22264636; PMCID: PMC3288504.
    28. Dutta P, Hullett DA, Roenneburg DA, Torrealba JR, Sollinger HW, Harn DA, Burlingham WJ. Lacto-N-fucopentaose III, a pentasaccharide, prolongs heart transplant survival. Transplantation. 2010 Nov 27; 90(10):1071-8. PMID: 20885339.
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    29. Da'dara AA, Harn DA. Elimination of helminth infection restores HIV-1C vaccine-specific T cell responses independent of helminth-induced IL-10. Vaccine. 2010 Feb 03; 28(5):1310-7. PMID: 19941988; PMCID: PMC2831209.
    30. Wang Y, Da'Dara AA, Thomas PG, Harn DA. Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses. Immunology. 2010 Mar; 129(3):406-17. PMID: 19922421; PMCID: PMC2826685.
    31. Dai Y, Zhu Y, Harn DA, Wang X, Tang J, Zhao S, Lu F, Guan X. DNA vaccination by electroporation and boosting with recombinant proteins enhances the efficacy of DNA vaccines for Schistosomiasis japonica. Clin Vaccine Immunol. 2009 Dec; 16(12):1796-803. PMID: 19812258; PMCID: PMC2786390.
    32. Harn DA, McDonald J, Atochina O, Da'dara AA. Modulation of host immune responses by helminth glycans. Immunol Rev. 2009 Jul; 230(1):247-57. PMID: 19594641.
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    33. Reis EA, Mauadi Carmo TA, Athanazio R, Reis MG, Harn DA. Schistosoma mansoni triose phosphate isomerase peptide MAP4 is able to trigger naïve donor immune response towards a type-1 cytokine profile. Scand J Immunol. 2008 Aug; 68(2):169-76. PMID: 18565118.
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    34. Reis EA, Athanazio DA, Cavada BS, Teixeira EH, de Paulo Teixeira Pinto V, Carmo TM, Reis A, Trocolli G, Croda J, Harn D, Barral-Netto M, Reis MG. Potential immunomodulatory effects of plant lectins in Schistosoma mansoni infection. Acta Trop. 2008 Nov-Dec; 108(2-3):160-5. PMID: 18579103.
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    35. Da'dara AA, Li YS, Xiong T, Zhou J, Williams GM, McManus DP, Feng Z, Yu XL, Gray DJ, Harn DA. DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo. Vaccine. 2008 Jul 04; 26(29-30):3617-25. PMID: 18524429; PMCID: PMC2567122.
    36. Reis EA, Athanazio DA, McBride AJ, Azevedo TM, Magalhães-Santos IF, Harn D, Reis MG. Influence of the HLA-DQB1*0201 allele on the immune response in a Schistosoma mansoni infection. Acta Trop. 2008 Nov-Dec; 108(2-3):131-4. PMID: 18495081.
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    37. Atochina O, Da'dara AA, Walker M, Harn DA. The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivo. Immunology. 2008 Sep; 125(1):111-21. PMID: 18373667; PMCID: PMC2526265.
    38. Reis EA, Azevedo TM, McBride AJ, Harn DA, Reis MG. Naïve donor responses to Schistosoma mansoni soluble egg antigens. Scand J Immunol. 2007 Dec; 66(6):662-70. PMID: 18021364.
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    39. Suruki RY, Mueller N, Hayashi K, Harn D, DeGruttola V, Raker CA, Tsubouchi H, Stuver SO. Host immune status and incidence of hepatocellular carcinoma among subjects infected with hepatitis C virus: a nested case-control study in Japan. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2521-5. PMID: 17164379.
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    40. Yu XL, He YK, Xiong T, Zhao YQ, Shi MZ, Zhou J, Liu ZC, Luo XS, Fu X, He HB, Harn DA, Li YS. [Protective effects of co-immunization with SjCTPI-Hsp70 and interleukin-12 DNA vaccines against Schistosoma japonicum challenge infection in water buffalo]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2006 Dec; 24(6):433-6. PMID: 17366973.
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    41. Pashov AD, Plaxco J, Kaveri SV, Monzavi-Karbassi B, Harn D, Kieber-Emmons T. Multiple antigenic mimotopes of HIV carbohydrate antigens: relating structure and antigenicity. J Biol Chem. 2006 Oct 06; 281(40):29675-83. PMID: 16899462.
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    42. Atochina O, Harn D. Prevention of psoriasis-like lesions development in fsn/fsn mice by helminth glycans. Exp Dermatol. 2006 Jun; 15(6):461-8. PMID: 16689863.
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    43. Birmann BM, Mueller NE, Okayama A, Hsieh CC, Tsubouchi H, Harn D, Stuver SO. Patterns of serum type 1 and type 2 immune markers in healthy carriers of HTLV-I. J Med Virol. 2006 Jun; 78(6):847-52. PMID: 16628590.
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    44. Da'Dara AA, Lautsch N, Dudek T, Novitsky V, Lee TH, Essex M, Harn DA. Helminth infection suppresses T-cell immune response to HIV-DNA-based vaccine in mice. Vaccine. 2006 Jun 12; 24(24):5211-9. PMID: 16675073.
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    45. Zhu Y, Si J, Harn DA, Xu M, Ren J, Yu C, Liang Y, Yin X, He W, Cao G. Schistosoma japonicum triose-phosphate isomerase plasmid DNA vaccine protects pigs against challenge infection. Parasitology. 2006 Jan; 132(Pt 1):67-71. PMID: 16393355.
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    46. Atochina O, Harn D. LNFPIII/LeX-stimulated macrophages activate natural killer cells via CD40-CD40L interaction. Clin Diagn Lab Immunol. 2005 Sep; 12(9):1041-9. PMID: 16148169; PMCID: PMC1235802.
    47. Ganley-Leal LM, Guarner J, Todd CW, Da'Dara AA, Freeman GL, Boyer AE, Harn DA, Secor WE. Comparison of Schistosoma mansoni irradiated cercariae and Sm23 DNA vaccines. Parasite Immunol. 2005 Sep; 27(9):341-9. PMID: 16149992.
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    48. Thomas PG, Carter MR, Da'dara AA, DeSimone TM, Harn DA. A helminth glycan induces APC maturation via alternative NF-kappa B activation independent of I kappa B alpha degradation. J Immunol. 2005 Aug 15; 175(4):2082-90. PMID: 16081774.
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    49. Da'dara AA, Harn DA. DNA vaccines against tropical parasitic diseases. Expert Rev Vaccines. 2005 Aug; 4(4):575-89. PMID: 16117713.
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    50. Zhao S, Zhu YC, Harn DA, Si J, Ren JG, Yin XR, He W, Liang YS, Xu M, Xu YL. [Enhancement of the protective effect of SjC23 DNA vaccine against Schistosoma japonicum infection by immunostimulatory sequence]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2005 Feb 28; 23(1):1-5. PMID: 16042196.
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    51. Mello MA, Mascarenhas RE, Ferraro GA, Harn D, Galvão-Castro M, Bou-Habib DC. Inhibition of HIV-1 infection by monoclonal antibodies to carbohydrates of Schistosoma mansoni. Med Microbiol Immunol. 2005 Jan; 194(1-2):61-5. PMID: 14634805.
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    52. Zhu Y, Ren J, Da'dara A, Harn D, Xu M, Si J, Yu C, Liang Y, Ye P, Yin X, He W, Xu Y, Cao G, Hua W. The protective effect of a Schistosoma japonicum Chinese strain 23 kDa plasmid DNA vaccine in pigs is enhanced with IL-12. Vaccine. 2004 Nov 15; 23(1):78-83. PMID: 15519710.
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    53. Zhu Y, Si J, Harn DA, Yu C, Liang Y, Ren J, Yin X, He W, Hua W. The protective immunity of a DNA vaccine encoding Schistosoma japonicum Chinese strain triose-phosphate isomerase in infected BALB/C mice. Southeast Asian J Trop Med Public Health. 2004 Sep; 35(3):518-22. PMID: 15689059.
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    54. Birmann BM, Mueller N, Okayama A, Hsieh CC, Tachibana N, Tsubouchi H, Lennette ET, Harn D, Stuver S. Serologic assessment of type 1 and type 2 immunity in healthy Japanese adults. Cancer Epidemiol Biomarkers Prev. 2004 Aug; 13(8):1385-91. PMID: 15298962.
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    55. Thomas PG, Harn DA. Immune biasing by helminth glycans. Cell Microbiol. 2004 Jan; 6(1):13-22. PMID: 14678327.
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    56. Thomas PG, Carter MR, Atochina O, Da'Dara AA, Piskorska D, McGuire E, Harn DA. Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism. J Immunol. 2003 Dec 01; 171(11):5837-41. PMID: 14634093.
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    57. Zhu Y, Ren J, Harn DA, Si J, Yu C, Ming X, Liang Y. Protective immunity induced with 23 kDa membrane protein dna vaccine of Schistosoma japonicum Chinese strain in infected C57BL/6 mice. Southeast Asian J Trop Med Public Health. 2003 Dec; 34(4):697-701. PMID: 15115073.
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    58. Da'Dara AA, Skelly PJ, Walker CM, Harn DA. A DNA-prime/protein-boost vaccination regimen enhances Th2 immune responses but not protection following Schistosoma mansoni infection. Parasite Immunol. 2003 Aug-Sep; 25(8-9):429-37. PMID: 14651590.
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    59. Skelly PJ, Da'dara A, Harn DA. Suppression of cathepsin B expression in Schistosoma mansoni by RNA interference. Int J Parasitol. 2003 Apr; 33(4):363-9. PMID: 12705930.
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    60. Hattori H, Okano M, Yamamoto T, Yoshino T, Yamashita Y, Watanabe T, Satoskar AR, Harn DA, Nishizaki K. Intranasal application of purified protein derivative suppresses the initiation but not the exacerbation of allergic rhinitis in mice. Clin Exp Allergy. 2002 Jun; 32(6):951-9. PMID: 12047444.
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    61. Da'dara AA, Skelly PJ, Fatakdawala M, Visovatti S, Eriksson E, Harn DA. Comparative efficacy of the Schistosoma mansoni nucleic acid vaccine, Sm23, following microseeding or gene gun delivery. Parasite Immunol. 2002 Apr; 24(4):179-87. PMID: 12010483.
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    62. Da'dara AA, Skelly PJ, Wang MM, Harn DA. Immunization with plasmid DNA encoding the integral membrane protein, Sm23, elicits a protective immune response against schistosome infection in mice. Vaccine. 2001 Nov 12; 20(3-4):359-69. PMID: 11672898.
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    63. Terrazas LI, Walsh KL, Piskorska D, McGuire E, Harn DA. The schistosome oligosaccharide lacto-N-neotetraose expands Gr1(+) cells that secrete anti-inflammatory cytokines and inhibit proliferation of naive CD4(+) cells: a potential mechanism for immune polarization in helminth infections. J Immunol. 2001 Nov 01; 167(9):5294-303. PMID: 11673545.
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    64. Okano M, Azuma M, Yoshino T, Hattori H, Nakada M, Satoskar AR, Harn DA, Nakayama E, Akagi T, Nishizaki K. Differential role of CD80 and CD86 molecules in the induction and the effector phases of allergic rhinitis in mice. Am J Respir Crit Care Med. 2001 Oct 15; 164(8 Pt 1):1501-7. PMID: 11704603.
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    65. Atochina O, Daly-Engel T, Piskorska D, McGuire E, Harn DA. A schistosome-expressed immunomodulatory glycoconjugate expands peritoneal Gr1(+) macrophages that suppress naive CD4(+) T cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism. J Immunol. 2001 Oct 15; 167(8):4293-302. PMID: 11591752.
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    66. Santos IK, Costa CH, Krieger H, Feitosa MF, Zurakowski D, Fardin B, Gomes RB, Weiner DL, Harn DA, Ezekowitz RA, Epstein JE. Mannan-binding lectin enhances susceptibility to visceral leishmaniasis. Infect Immun. 2001 Aug; 69(8):5212-5. PMID: 11447210; PMCID: PMC98624.
    67. Da'dara A, Tsai MH, Tao LF, Marx KA, Shoemaker CB, Harn DA, Skelly PJ. Schistosoma mansoni: molecular characterization of a tegumental Ca-ATPase (SMA3). Exp Parasitol. 2001 Aug; 98(4):215-22. PMID: 11560414.
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    68. Okano M, Satoskar AR, Nishizaki K, Harn DA. Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response. J Immunol. 2001 Jul 01; 167(1):442-50. PMID: 11418681.
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    69. Yamatomo T, Okano M, Ono T, Nakayama E, Yoshino T, Satoskar AR, Harn DA, Nishizaki K. Sex-related differences in the initiation of allergic rhinitis in mice. Allergy. 2001 Jun; 56(6):525-31. PMID: 11421897.
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    70. Ren JG, Zhu YC, Harn DA, Yu CX, Yin XR, Si J, He W, Xu M, Hua WQ, Xu YL. [Protective immunity induced by 23 kDa membrane protein DNA vaccine of Schistosoma japonicum Chinese strain in mice]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001; 19(6):336-9. PMID: 12572063.
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    71. Okano M, Satoskar AR, Abe M, Harn DA, Okano M, Nishizaki K, Takeda Y, Yoshino T, Brombacher F, Satoskar AA. Interleukin-4-independent production of Th2 cytokines by nasal lymphocytes and nasal eosinophilia in murine allergic rhinitis. Allergy. 2000 Aug; 55(8):723-31. PMID: 10955698.
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    72. Ribeiro de Jesus A, Araújo I, Bacellar O, Magalhães A, Pearce E, Harn D, Strand M, Carvalho EM. Human immune responses to Schistosoma mansoni vaccine candidate antigens. Infect Immun. 2000 May; 68(5):2797-803. PMID: 10768975; PMCID: PMC97490.
    73. Velupillai P, dos Reis EA, dos Reis MG, Harn DA. Lewis(x)-containing oligosaccharide attenuates schistosome egg antigen-induced immune depression in human schistosomiasis. Hum Immunol. 2000 Mar; 61(3):225-32. PMID: 10689112.
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    74. Okano M, Satoskar AR, Nishizaki K, Abe M, Harn DA. Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigens. J Immunol. 1999 Dec 15; 163(12):6712-7. PMID: 10586068.
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    75. Okano M, Nishizaki K, Satoskar AR, Yoshino T, Masuda Y, Harn DA. Involvement of carbohydrate on phospholipase A2, a bee-venom allergen, in in vivo antigen-specific IgE synthesis in mice. Allergy. 1999 Aug; 54(8):811-8. PMID: 10485384.
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    76. Okano M, Nishizaki K, Abe M, Wang MM, Yoshino T, Satoskar AR, Masuda Y, Harn DA. Strain-dependent induction of allergic rhinitis without adjuvant in mice. Allergy. 1999 Jun; 54(6):593-601. PMID: 10435473.
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    77. She J, Ruzek MC, Velupillai P, de Aos I, Wang B, Harn DA, Sancho J, Biron CA, Terhorst C. Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3zeta. Int Immunol. 1999 May; 11(5):845-57. PMID: 10330289.
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    78. Hernandez HJ, Edson CM, Harn DA, Ianelli CJ, Stadecker MJ. Schistosoma mansoni: genetic restriction and cytokine profile of the CD4 + T helper cell response to dominant epitope peptide of major egg antigen Sm-p40. Exp Parasitol. 1998 Sep; 90(1):122-30. PMID: 9709038.
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    79. Maron R, Palanivel V, Weiner HL, Harn DA. Oral administration of schistosome egg antigens and insulin B-chain generates and enhances Th2-type responses in NOD mice. Clin Immunol Immunopathol. 1998 Apr; 87(1):85-92. PMID: 9576014.
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    80. Ferru I, Georges B, Bossus M, Estaquier J, Delacre M, Harn DA, Tartar A, Capron A, Grassmasse H, Auriault C. Analysis of the immune response elicited by a multiple antigen peptide (MAP) composed of two distinct protective antigens derived from the parasite Schistosoma mansoni. Parasite Immunol. 1997 Jan; 19(1):1-11. PMID: 9121835.
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    81. Velupillai P, Secor WE, Horauf AM, Harn DA. B-1 cell (CD5+B220+) outgrowth in murine schistosomiasis is genetically restricted and is largely due to activation by polylactosamine sugars. J Immunol. 1997 Jan 01; 158(1):338-44. PMID: 8977208.
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    82. Velupillai P, Sypek J, Harn DA. Interleukin-12 and -10 and gamma interferon regulate polyclonal and ligand-specific expansion of murine B-1 cells. Infect Immun. 1996 Nov; 64(11):4557-60. PMID: 8890206; PMCID: PMC174412.
    83. Secor WE, del Corral H, dos Reis MG, Ramos EA, Zimon AE, Matos EP, Reis EA, do Carmo TM, Hirayama K, David RA, David JR, Harn DA. Association of hepatosplenic schistosomiasis with HLA-DQB1*0201. J Infect Dis. 1996 Nov; 174(5):1131-5. PMID: 8896524.
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    84. Palanivel V, Posey C, Horauf AM, Solbach W, Piessens WF, Harn DA. B-cell outgrowth and ligand-specific production of IL-10 correlate with Th2 dominance in certain parasitic diseases. Exp Parasitol. 1996 Nov; 84(2):168-77. PMID: 8932766.
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    85. El Ridi R, Velupillai P, Harn DA. Regulation of schistosome egg granuloma formation: host-soluble L-selectin enters tissue-trapped eggs and binds to carbohydrate antigens on surface membranes of miracidia. Infect Immun. 1996 Nov; 64(11):4700-5. PMID: 8890228; PMCID: PMC174434.
    86. Richter D, Incani RN, Harn DA. Lacto-N-fucopentaose III (Lewis x), a target of the antibody response in mice vaccinated with irradiated cercariae of Schistosoma mansoni. Infect Immun. 1996 May; 64(5):1826-31. PMID: 8613397; PMCID: PMC173998.
    87. Richter D, Harn DA, Matuschka FR. The irradiated cercariae vaccine model: looking on the bright side of radiation. Parasitol Today. 1995 Aug; 11(8):288-93. PMID: 15275325.
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    88. Shoemaker CB, Reynolds SR, Wei G, Tielens AG, Harn DA. Schistosoma mansoni hexokinase: cDNA cloning and immunogenicity studies. Exp Parasitol. 1995 Feb; 80(1):36-45. PMID: 7821409.
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    89. Harn DA, Reynolds SR, Chikunguwo S, Furlong S, Dahl C. Synthetic peptide vaccines for schistosomiasis. Pharm Biotechnol. 1995; 6:891-905. PMID: 7551254.
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    90. Hirayama K, Abrams JS, Quinn JJ, Harn DA. Heterogeneity of antigen-specific CD4+ T cell clones from a patient with Schistosomiasis mansoni. Parasite Immunol. 1994 Nov; 16(11):561-9. PMID: 7862462.
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    91. Secor WE, dos Reis MG, Ramos EA, Matos EP, Reis EA, do Carmo TM, Harn DA. Soluble intercellular adhesion molecules in human schistosomiasis: correlations with disease severity and decreased responsiveness to egg antigens. Infect Immun. 1994 Jul; 62(7):2695-701. PMID: 7516309; PMCID: PMC302870.
    92. Skelly PJ, Secor WE, Reis MG, Ramos EA, Carmo TM, Peixoto EE, Harn DA. Failure of schistosomiasis to significantly decrease testosterone levels in Brazilian men. Am J Trop Med Hyg. 1994 Jul; 51(1):40-4. PMID: 8059914.
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    93. Velupillai P, Harn DA. Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: a mechanism for regulation of CD4+ T-cell subsets. Proc Natl Acad Sci U S A. 1994 Jan 04; 91(1):18-22. PMID: 7904066; PMCID: PMC42877.
    94. Reynolds SR, Dahl CE, Harn DA. T and B epitope determination and analysis of multiple antigenic peptides for the Schistosoma mansoni experimental vaccine triose-phosphate isomerase. J Immunol. 1994 Jan 01; 152(1):193-200. PMID: 7504709.
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    95. Zhu YC, Harn DA, Quinn JJ. Characterization of isoelectric point (pI) fractions of soluble egg antigen of Schistosoma japonicum. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1994; 12(1):13-9. PMID: 8044897.
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    96. Richter D, Incani RN, Harn DA. Isotype responses to candidate vaccine antigens in protective sera obtained from mice vaccinated with irradiated cercariae of Schistosoma mansoni. Infect Immun. 1993 Jul; 61(7):3003-11. PMID: 8514407; PMCID: PMC280952.
    97. Richter D, Reynolds SR, Harn DA. Candidate vaccine antigens that stimulate the cellular immune response of mice vaccinated with irradiated cercariae of Schistosoma mansoni. J Immunol. 1993 Jul 01; 151(1):256-65. PMID: 8326127.
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    98. Chikunguwo SM, Quinn JJ, Harn DA, Stadecker MJ. The cell-mediated response to schistosomal antigens at the clonal level. III. Identification of soluble egg antigens recognized by cloned specific granulomagenic murine CD4+ Th1-type lymphocytes. J Immunol. 1993 Feb 15; 150(4):1413-21. PMID: 8094407.
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    99. Richter D, Harn DA. Candidate vaccine antigens identified by antibodies from mice vaccinated with 15- or 50-kilorad-irradiated cercariae of Schistosoma mansoni. Infect Immun. 1993 Jan; 61(1):146-54. PMID: 8418037; PMCID: PMC302699.
    100. Reynolds SR, Shoemaker CB, Harn DA. T and B cell epitope mapping of SM23, an integral membrane protein of Schistosoma mansoni. J Immunol. 1992 Dec 15; 149(12):3995-4001. PMID: 1281197.
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    101. Chikunguwo SM, Harris TS, Brodeur PH, Harn DA, Stadecker MJ. The cell-mediated response to schistosomal antigens at the clonal level: development and characterization of a panel of egg antigen-specific murine T cell clones. Eur J Immunol. 1992 Apr; 22(4):917-22. PMID: 1348031.
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    102. Shoemaker C, Gross A, Gebremichael A, Harn D. cDNA cloning and functional expression of the Schistosoma mansoni protective antigen triose-phosphate isomerase. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1842-6. PMID: 1542681; PMCID: PMC48549.
    103. Harn DA, Gu W, Oligino LD, Mitsuyama M, Gebremichael A, Richter D. A protective monoclonal antibody specifically recognizes and alters the catalytic activity of schistosome triose-phosphate isomerase. J Immunol. 1992 Jan 15; 148(2):562-7. PMID: 1729373.
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    104. Xu AL, Zhou XY, Wang BF, Harn DA. [Generation and immunochemical characterization of an anti-egg monoclonal antibody specific to Schistosoma japonicum]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1992; 10(1):26-9. PMID: 1394890.
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    105. Reynolds SR, Harn DA. Comparison of irradiated-cercaria schistosome vaccine models that use 15- and 50-kilorad doses: the 15-kilorad dose gives greater protection, smaller liver sizes, and higher gamma interferon levels after challenge. Infect Immun. 1992 Jan; 60(1):90-4. PMID: 1729200; PMCID: PMC257507.
    106. Ko AI, Dräger UC, Harn DA. A Schistosoma mansoni epitope recognized by a protective monoclonal antibody is identical to the stage-specific embryonic antigen 1. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4159-63. PMID: 1971946; PMCID: PMC54067.
    107. Silberstein DS, David JR, Harn DA. The ability of mouse monoclonal antibodies to direct the cytotoxic function of cytokine-activated human eosinophils. Hybridoma. 1990 Jun; 9(3):237-42. PMID: 2194934.
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    108. Stein LD, Harn DA, David JR. A cloned ATP:guanidino kinase in the trematode Schistosoma mansoni has a novel duplicated structure. J Biol Chem. 1990 Apr 25; 265(12):6582-8. PMID: 2324092.
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    109. Harn DA, Danko K, Quinn JJ, Stadecker MJ. Schistosoma mansoni: the host immune response to egg antigens. I. Partial characterization of cellular and humoral responses to pI fractions of soluble egg antigens. J Immunol. 1989 Mar 15; 142(6):2061-6. PMID: 2493503.
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    110. Harn DA, Cianci CM, Caulfield JP. Schistosoma mansoni: immunization with cercarial glycocalyx preparation increases the adult worm burden. Exp Parasitol. 1989 Jan; 68(1):108-10. PMID: 2492946.
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    111. Omer Ali P, Smithers SR, Bickle Q, Phillips SM, Harn D, Simpson AJ. Analysis of the anti-Schistosoma mansoni surface antibody response during murine infection and its potential contribution to protective immunity. J Immunol. 1988 May 01; 140(9):3273-9. PMID: 3129516.
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    112. Percy AJ, Harn DA. Monoclonal anti-idiotypic and anti-anti-idiotypic antibodies from mice immunized with a protective monoclonal antibody against Schistosoma mansoni. J Immunol. 1988 Apr 15; 140(8):2760-2. PMID: 3128609.
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    113. Oligino LD, Percy AJ, Harn DA. Purification and immunochemical characterization of a 22 kilodalton surface antigen from Schistosoma mansoni. Mol Biochem Parasitol. 1988 Mar; 28(2):95-103. PMID: 2452982.
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    114. Harn DA, Quinn JJ, Cianci CM, Ko AI. Evidence that a protective membrane epitope is involved in early but not late phase immunity in Schistosoma mansoni. J Immunol. 1987 Mar 01; 138(5):1571-80. PMID: 2433351.
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    115. Ko AI, Harn DA. Characterization of protective and non-protective surface membrane carbohydrate epitopes of Schistosoma mansoni. Mem Inst Oswaldo Cruz. 1987; 82 Suppl 4:115-9. PMID: 2474123.
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    116. Harn DA, Mitsuyama M, Huguenel ED, David JR. Schistosoma mansoni: detection by monoclonal antibody of a 22,000-dalton surface membrane antigen which may be blocked by host molecules on lung stage parasites. J Immunol. 1985 Sep; 135(3):2115-20. PMID: 4020141.
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    117. Harn DA, Mitsuyama M, Huguenel ED, Oligino L, David JR. Identification by monoclonal antibody of a major (28 kDa) surface membrane antigen of Schistosoma mansoni. Mol Biochem Parasitol. 1985 Sep; 16(3):345-54. PMID: 4058486.
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    118. Harn DA, Mitsuyama M, David JR. Schistosoma mansoni. Anti-egg monoclonal antibodies protect against cercarial challenge in vivo. J Exp Med. 1984 May 01; 159(5):1371-87. PMID: 6538899; PMCID: PMC2187298.
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