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Professor Alain Dessein

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fleury A, Alaez C, Dessein A, Rosetti M, Saenz B, Hernández M, Bobes RJ, Ramírez-Aquino R, Sciutto E, Gorodezky C, Fragoso G. No association of IL2, IL4, IL6, TNF, and IFNG gene polymorphisms was found with Taenia solium human infection or neurocysticercosis severity in a family-based study. Hum Immunol. 2018 Jul; 79(7):578-582. PMID: 29684412.
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    2. Cabantous S, Hou X, Louis L, He H, Mariani O, Sastre X, Daujat-Chavanieu M, Li Y, Dessein A. Evidence for an important role of host microRNAs in regulating hepatic fibrosis in humans infected with Schistosoma japonicum. Int J Parasitol. 2017 11; 47(13):823-830. PMID: 28739251.
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    3. Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, Li J, Oyegue S, Arnaud V, Luo X, Daujat-Chavanieu M, Chavanieu M, Mariani O, Sastre X, Dombey AM, He H, Li Y, Dessein A. FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly. PLoS Negl Trop Dis. 2016 Jan; 10(1):e0004306. PMID: 26731721.
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    4. Masi B, Perles-Barbacaru TA, Laprie C, Dessein H, Bernard M, Dessein A, Viola A. Correction: In Vivo MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosmiasis. PLoS Negl Trop Dis. 2015 Oct; 9(10):e0004174. PMID: 26474175.
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    5. Castellano LR, Argiro L, Dessein H, Dessein A, da Silva MV, Correia D, Rodrigues V. Potential Use of Interleukin-10 Blockade as a Therapeutic Strategy in Human Cutaneous Leishmaniasis. J Immunol Res. 2015; 2015:152741. PMID: 26495321.
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    6. Masi B, Perles-Barbacaru TA, Laprie C, Dessein H, Bernard M, Dessein A, Viola A. In Vivo MRI Assessment of Hepatic and Splenic Disease in a Murine Model of Schistosomiasis [corrected]. PLoS Negl Trop Dis. 2015 Sep; 9(9):e0004036. PMID: 26394390.
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    7. Souza MA, Almeida TM, Castro MC, Oliveira-Mendes AP, Almeida AF, Oliveira BC, Rocha LF, Medeiros AC, Brito ME, Dessein AJ, Pereira VR. American tegumentary leishmaniasis: mRNA expression for Th1 and Treg mediators are predominant in patients with recent active disease. Immunobiology. 2016 Feb; 221(2):253-9. PMID: 26572279.
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    8. Sertorio M, Carmo RF, Cabantous S, Vasconcelos L, Pereira LB, Moura P, Dessein A. Reply: To PMID 25476703. Hepatology. 2015 Dec; 62(6):1920. PMID: 25907639.
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    9. Cabantous S, Ranque S, Poudiougou B, Traore A, Berbache S, Vitte J, Bongrand P, Doumbo O, Dessein AJ, Abel L, Marquet S. Genotype combinations of two IL4 polymorphisms influencing IL-4 plasma levels are associated with different risks of severe malaria in the Malian population. Immunogenetics. 2015 Jun; 67(5-6):283-8. PMID: 25935236.
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    10. Sertorio M, Hou X, Carmo RF, Dessein H, Cabantous S, Abdelwahed M, Romano A, Albuquerque F, Vasconcelos L, Carmo T, Li J, Varoquaux A, Arnaud V, Oliveira P, Hamdoun A, He H, Adbelmaboud S, Mergani A, Zhou J, Monis A, Pereira LB, Halfon P, Bourlière M, Parana R, Dos Reis M, Gonnelli D, Moura P, Elwali NE, Argiro L, Li Y, Dessein A. IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections. Hepatology. 2015 Apr; 61(4):1321-31. PMID: 25476703.
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    11. Oliveira PR, Dessein H, Romano A, Cabantous S, de Brito ME, Santoro F, Pitta MG, Pereira V, Pontes-de-Carvalho LC, Rodrigues V, Rafati S, Argiro L, Dessein AJ. IL2RA genetic variants reduce IL-2-dependent responses and aggravate human cutaneous leishmaniasis. J Immunol. 2015 Mar 15; 194(6):2664-72. PMID: 25672756.
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    12. Dessein A, Arnaud V, He H, Li J, Dessein H, Hou X, Luo X, Li Y. Genetic analysis of human predisposition to hepatosplenic disease caused by schistosomes reveals the crucial role of connective tissue growth factor in rapid progression to severe hepatic fibrosis. Pathol Biol (Paris). 2013 Jan; 61(1):3-10. PMID: 23414795.
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    13. Rougeron V, De Meeûs T, Hide M, Le Falher G, Bucheton B, Dereure J, El-Safi SH, Dessein A, Bañuls AL. Multifaceted population structure and reproductive strategy in Leishmania donovani complex in one Sudanese village. PLoS Negl Trop Dis. 2011 Dec; 5(12):e1448. PMID: 22206035.
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    14. Halfon P, Bourliere M, Ouzan D, Maor Y, Renou C, Wartelle C, Pénaranda G, Tran A, Botta D, Oules V, Castellani P, Portal I, Argiro L, Dessein A. A single IL28B genotype SNP rs12979860 determination predicts treatment response in patients with chronic hepatitis C Genotype 1 virus. Eur J Gastroenterol Hepatol. 2011 Oct; 23(10):931-5. PMID: 21900787.
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    15. Castellano LR, Gave TC, Lira MA, Dessein H, Dessein A, Correia D, Rodrigues V. Evaluation of electro-eluted antigens in the serological diagnosis of cutaneous leishmaniasis. Ann Trop Med Parasitol. 2010 Jun; 104(4):347-50. PMID: 20659396.
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    16. Rahoud SA, Mergani A, Khamis AH, Saeed OK, Mohamed-Ali Q, Dessein AJ, Elwali NE. Factors controlling the effect of praziquantel on liver fibrosis in Schistosoma mansoni-infected patients. FEMS Immunol Med Microbiol. 2010 Feb; 58(1):106-12. PMID: 20030714.
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    17. Cabantous S, Poudiougou B, Oumar AA, Traore A, Barry A, Vitte J, Bongrand P, Marquet S, Doumbo O, Dessein AJ. Genetic evidence for the aggravation of Plasmodium falciparum malaria by interleukin 4. J Infect Dis. 2009 Nov 15; 200(10):1530-9. PMID: 19835477.
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    18. Dessein A, Chevillard C, Arnaud V, Hou X, Hamdoun AA, Dessein H, He H, Abdelmaboud SA, Luo X, Li J, Varoquaux A, Mergani A, Abdelwahed M, Zhou J, Monis A, Pitta MG, Gasmelseed N, Cabantous S, Zhao Y, Prata A, Brandt C, Elwali NE, Argiro L, Li Y. Variants of CTGF are associated with hepatic fibrosis in Chinese, Sudanese, and Brazilians infected with schistosomes. J Exp Med. 2009 Oct 26; 206(11):2321-8. PMID: 19822645.
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    19. Pitta MG, Romano A, Cabantous S, Henri S, Hammad A, Kouriba B, Argiro L, el Kheir M, Bucheton B, Mary C, El-Safi SH, Dessein A. IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani. J Clin Invest. 2009 Aug; 119(8):2379-87. PMID: 19620772.
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    20. Castellano LR, Filho DC, Argiro L, Dessein H, Prata A, Dessein A, Rodrigues V. Th1/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-gamma production. Hum Immunol. 2009 Jun; 70(6):383-90. PMID: 19480861.
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    21. Arnaud V, Li J, Wang Y, Fu X, Mengzhi S, Luo X, Hou X, Dessein H, Jie Z, Xin-Ling Y, He H, McManus DP, Li Y, Dessein A. Regulatory role of interleukin-10 and interferon-gamma in severe hepatic central and peripheral fibrosis in humans infected with Schistosoma japonicum. J Infect Dis. 2008 Aug 01; 198(3):418-26. PMID: 18582197.
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    22. Salhi A, Rodrigues V, Santoro F, Dessein H, Romano A, Castellano LR, Sertorio M, Rafati S, Chevillard C, Prata A, Alcaïs A, Argiro L, Dessein A. Immunological and genetic evidence for a crucial role of IL-10 in cutaneous lesions in humans infected with Leishmania braziliensis. J Immunol. 2008 May 01; 180(9):6139-48. PMID: 18424735.
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    23. Marquet S, Doumbo O, Cabantous S, Poudiougou B, Argiro L, Safeukui I, Konate S, Sissoko S, Chevereau E, Traore A, Keita MM, Chevillard C, Abel L, Dessein AJ. A functional promoter variant in IL12B predisposes to cerebral malaria. Hum Mol Genet. 2008 Jul 15; 17(14):2190-5. PMID: 18413324.
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    24. He H, Isnard A, Kouriba B, Cabantous S, Dessein A, Doumbo O, Chevillard C. A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis. Genes Immun. 2008 Apr; 9(3):195-206. PMID: 18273035.
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    25. Ranque S, Poudiougou B, Traoré A, Keita M, Oumar AA, Safeukui I, Marquet S, Cabantous S, Diakité M, Mintha D, Cissé MB, Keita MM, Dessein AJ, Doumbo OK. Life-threatening malaria in African children: a prospective study in a mesoendemic urban setting. Pediatr Infect Dis J. 2008 Feb; 27(2):130-5. PMID: 18174865.
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    26. Granel B, Chevillard C, Dessein A. [Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis]. Rev Med Interne. 2007 Sep; 28(9):613-22. PMID: 17543424.
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    27. Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ. Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis. Genes Immun. 2007 Jan; 8(1):79-83. PMID: 17108990.
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    28. Campino S, Kwiatkowski D, Dessein A. Mendelian and complex genetics of susceptibility and resistance to parasitic infections. Semin Immunol. 2006 Dec; 18(6):411-22. PMID: 17023176.
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    29. Cabantous S, Doumbo O, Ranque S, Poudiougou B, Traore A, Hou X, Keita MM, Cisse MB, Dessein AJ, Marquet S. Alleles 308A and 238A in the tumor necrosis factor alpha gene promoter do not increase the risk of severe malaria in children with Plasmodium falciparum infection in Mali. Infect Immun. 2006 Dec; 74(12):7040-2. PMID: 16982833.
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    30. Granel B, Allanore Y, Chevillard C, Arnaud V, Marquet S, Weiller PJ, Durand JM, Harlé JR, Grange C, Frances Y, Berbis P, Gaudart J, de Micco P, Kahan A, Dessein A. IL13RA2 gene polymorphisms are associated with systemic sclerosis. J Rheumatol. 2006 Oct; 33(10):2015-9. PMID: 16981293.
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    31. El-Safi S, Kheir MM, Bucheton B, Argiro L, Abel L, Dereure J, Dedet JP, Dessein A. Genes and environment in susceptibility to visceral leishmaniasis. C R Biol. 2006 Nov; 329(11):863-70. PMID: 17067929.
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    32. Granel B, Chevillard C, Allanore Y, Arnaud V, Cabantous S, Marquet S, Weiller PJ, Durand JM, Harlé JR, Grange C, Frances Y, Berbis P, Gaudart J, de Micco P, Kahan A, Dessein A. Evaluation of interleukin 13 polymorphisms in systemic sclerosis. Immunogenetics. 2006 Aug; 58(8):693-9. PMID: 16832637.
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    33. Courtin D, Argiro L, Jamonneau V, N'dri L, N'guessan P, Abel L, Dessein A, Cot M, Laveissiere C, Garcia A. Interest of tumor necrosis factor-alpha -308 G/A and interleukin-10 -592 C/A polymorphisms in human African trypanosomiasis. Infect Genet Evol. 2006 Mar; 6(2):123-9. PMID: 15894515.
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    34. Fleury A, Morales J, Bobes RJ, Dumas M, Yánez O, Piña J, Carrillo-Mezo R, Martínez JJ, Fragoso G, Dessein A, Larralde C, Sciutto E. An epidemiological study of familial neurocysticercosis in an endemic Mexican community. Trans R Soc Trop Med Hyg. 2006 Jun; 100(6):551-8. PMID: 16316671.
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    35. Kouriba B, Traore HA, Dabo A, Sangare L, Guindo H, Keita AS, Reimert CM, van Dam GJ, Deelder AM, Doumbo O, Dessein AJ. Urinary disease in 2 Dogon populations with different exposure to Schistosoma haematobium infection: progression of bladder and kidney diseases in children and adults. J Infect Dis. 2005 Dec 15; 192(12):2152-9. PMID: 16288382.
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    36. Cabantous S, Poudiougou B, Traore A, Keita M, Cisse MB, Doumbo O, Dessein AJ, Marquet S. Evidence that interferon-gamma plays a protective role during cerebral malaria. J Infect Dis. 2005 Sep 01; 192(5):854-60. PMID: 16088835.
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    37. Kouriba B, Chevillard C, Bream JH, Argiro L, Dessein H, Arnaud V, Sangare L, Dabo A, Beavogui AH, Arama C, Traoré HA, Doumbo O, Dessein A. Analysis of the 5q31-q33 locus shows an association between IL13-1055C/T IL-13-591A/G polymorphisms and Schistosoma haematobium infections. J Immunol. 2005 May 15; 174(10):6274-81. PMID: 15879126.
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    38. Granel B, Chevillard C, Dessein A. [Genetic factors predisposing to fibrosis in systemic sclerosis]. Rev Med Interne. 2005 Apr; 26(4):294-303. PMID: 15820565.
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    39. Ranque S, Safeukui I, Poudiougou B, Traoré A, Keita M, Traoré D, Diakité M, Cissé MB, Keita MM, Doumbo OK, Dessein AJ. Familial aggregation of cerebral malaria and severe malarial anemia. J Infect Dis. 2005 Mar 01; 191(5):799-804. PMID: 15688298.
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    40. Dessein A, Kouriba B, Eboumbou C, Dessein H, Argiro L, Marquet S, Elwali NE, Rodrigues V, Li Y, Doumbo O, Chevillard C. Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human schistosomiasis. Immunol Rev. 2004 Oct; 201:180-90. PMID: 15361241.
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    41. Fleury A, Dessein A, Preux PM, Dumas M, Tapia G, Larralde C, Sciutto E. Symptomatic human neurocysticercosis--age, sex and exposure factors relating with disease heterogeneity. J Neurol. 2004 Jul; 251(7):830-7. PMID: 15258785.
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    42. Safeukui-Noubissi I, Ranque S, Poudiougou B, Keita M, Traoré A, Traoré D, Diakité M, Cissé MB, Keita MM, Dessein A, Doumbo OK. Risk factors for severe malaria in Bamako, Mali: a matched case-control study. Microbes Infect. 2004 May; 6(6):572-8. PMID: 15158191.
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    43. Martin F, Penet MF, Malergue F, Lepidi H, Dessein A, Galland F, de Reggi M, Naquet P, Gharib B. Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores. J Clin Invest. 2004 Feb; 113(4):591-7. PMID: 14966568.
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    44. Chevillard C, Moukoko CE, Elwali NE, Bream JH, Kouriba B, Argiro L, Rahoud S, Mergani A, Henri S, Gaudart J, Mohamed-Ali Q, Young HA, Dessein AJ. IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni). J Immunol. 2003 Nov 15; 171(10):5596-601. PMID: 14607968.
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    45. Bucheton B, Abel L, El-Safi S, Kheir MM, Pavek S, Lemainque A, Dessein AJ. A major susceptibility locus on chromosome 22q12 plays a critical role in the control of kala-azar. Am J Hum Genet. 2003 Nov; 73(5):1052-60. PMID: 14557985.
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    46. Dereure J, El-Safi SH, Bucheton B, Boni M, Kheir MM, Davoust B, Pratlong F, Feugier E, Lambert M, Dessein A, Dedet JP. Visceral leishmaniasis in eastern Sudan: parasite identification in humans and dogs; host-parasite relationships. Microbes Infect. 2003 Oct; 5(12):1103-8. PMID: 14554251.
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    47. Chavarría A, Roger B, Fragoso G, Tapia G, Fleury A, Dumas M, Dessein A, Larralde C, Sciutto E. TH2 profile in asymptomatic Taenia solium human neurocysticercosis. Microbes Infect. 2003 Oct; 5(12):1109-15. PMID: 14554252.
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    48. Moukoko CE, El Wali N, Saeed OK, Mohamed-Ali Q, Gaudart J, Dessein AJ, Chevillard C. No evidence for a major effect of tumor necrosis factor alpha gene polymorphisms in periportal fibrosis caused by Schistosoma mansoni infection. Infect Immun. 2003 Oct; 71(10):5456-60. PMID: 14500462.
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    49. Mduluza T, Ndhlovu PD, Midzi N, Scott JT, Mutapi F, Mary C, Couissinier-Paris P, Turner CM, Chandiwana SK, Woolhouse ME, Dessein AJ, Hagan P. Contrasting cellular responses in Schistosoma haematobium infected and exposed individuals from areas of high and low transmission in Zimbabwe. Immunol Lett. 2003 Sep 08; 88(3):249-56. PMID: 12941484.
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    50. Buchetont B, El-Safi SH, Hammad A, Kheir MM, Eudes N, Mirgani A, Dessein AJ, Mary C. Antileishmanial antibodies in an outbreak of visceral leishmaniasis in eastern Sudan: high antibody responses occur in resistant subjects and are not predictive of disease. Trans R Soc Trop Med Hyg. 2003 Jul-Aug; 97(4):463-8. PMID: 15259483.
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    51. Bucheton B, Abel L, Kheir MM, Mirgani A, El-Safi SH, Chevillard C, Dessein A. Genetic control of visceral leishmaniasis in a Sudanese population: candidate gene testing indicates a linkage to the NRAMP1 region. Genes Immun. 2003 Mar; 4(2):104-9. PMID: 12618857.
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    52. Fleury A, Gomez T, Alvarez I, Meza D, Huerta M, Chavarria A, Carrillo Mezo RA, Lloyd C, Dessein A, Preux PM, Dumas M, Larralde C, Sciutto E, Fragoso G. High prevalence of calcified silent neurocysticercosis in a rural village of Mexico. Neuroepidemiology. 2003 Mar-Apr; 22(2):139-45. PMID: 12629280.
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    53. Bucheton B, Kheir MM, El-Safi SH, Hammad A, Mergani A, Mary C, Abel L, Dessein A. The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan. Microbes Infect. 2002 Nov; 4(14):1449-57. PMID: 12475635.
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    54. EL-Safi SH, Bucheton B, Kheir MM, Musa HA, EL-Obaid M, Hammad A, Dessein A. Epidemiology of visceral leishmaniasis in Atbara River area, eastern Sudan: the outbreak of Barbar El Fugara village (1996-1997). Microbes Infect. 2002 Nov; 4(14):1439-47. PMID: 12475634.
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    55. Lambert M, Dereure J, El-Safi SH, Bucheton B, Dessein A, Boni M, Feugier E, Dedet JP. The sandfly fauna in the visceral-leishmaniasis focus of Gedaref, in the Atbara-River area of eastern Sudan. Ann Trop Med Parasitol. 2002 Sep; 96(6):631-6. PMID: 12396326.
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    56. Henri S, Chevillard C, Mergani A, Paris P, Gaudart J, Camilla C, Dessein H, Montero F, Elwali NE, Saeed OK, Magzoub M, Dessein AJ. Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-gamma is associated with protection against fibrosis and TNF-alpha with aggravation of disease. J Immunol. 2002 Jul 15; 169(2):929-36. PMID: 12097398.
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    57. Li YS, Sleigh AC, Li Y, Tanner M, Dessein A, Williams GM, McManus DP. Five-year impact of repeated praziquantel treatment on subclinical morbidity due to Schistosoma japonicum in China. Trans R Soc Trop Med Hyg. 2002 Jul-Aug; 96(4):438-43. PMID: 12497984.
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    58. Henri S, Stefani F, Parzy D, Eboumbou C, Dessein A, Chevillard C. Description of three new polymorphisms in the intronic and 3'UTR regions of the human interferon gamma gene. Genes Immun. 2002 Feb; 3(1):1-4. PMID: 11857052.
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    59. Chevillard C, Henri S, Stefani F, Parzy D, Dessein A. Two new polymorphisms in the human interferon gamma (IFN-gamma) promoter. Eur J Immunogenet. 2002 Feb; 29(1):53-6. PMID: 11841489.
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    60. Zinn-Justin A, Marquet S, Hillaire D, Dessein A, Abel L. Genome search for additional human loci controlling infection levels by Schistosoma mansoni. Am J Trop Med Hyg. 2001 Dec; 65(6):754-8. PMID: 11791970.
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    61. Ranque S, Dessein A. [Schistosoma mansoni schistosomiasis]. Rev Prat. 2001 Dec 01; 51(19):2099-103. PMID: 11842728.
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    62. Pratlong F, Dereure J, Bucheton B, El-Saf S, Dessein A, Lanotte G, Dedet JP. Sudan: the possible original focus of visceral leishmaniasis. Parasitology. 2001 Jun; 122(Pt 6):599-605. PMID: 11444612.
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    63. Dessein AJ, Chevillard C, Marquet S, Henri S, Hillaire D, Dessein H. Genetics of parasitic infections. Drug Metab Dispos. 2001 Apr; 29(4 Pt 2):484-8. PMID: 11259337.
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    64. Mduluza T, Ndhlovu PD, Midzi N, Mary C, Paris CP, Turner CM, Chandiwana SK, Woolhouse ME, Dessein AJ, Hagan P. T cell clones from Schistosoma haematobium infected and exposed individuals lacking distinct cytokine profiles for Th1/Th2 polarisation. Mem Inst Oswaldo Cruz. 2001; 96 Suppl:89-101. PMID: 11586432.
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    65. Argiro LL, Kohlstädt SS, Henri SS, Dessein HH, Matabiau VV, Paris PP, Bourgois AA, Dessein AJ. Identification of a candidate vaccine peptide on the 37 kDa Schistosoma mansoni GAPDH. Vaccine. 2000 Apr 03; 18(19):2039-48. PMID: 10706967.
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    66. Argiro L, Henri S, Dessein H, Kouriba B, Dessein AJ, Bourgois A. Induction of a protection against S. mansoni with a MAP containing epitopes of Sm37-GAPDH and Sm10-DLC. Effect of coadsorption with GM-CSF on alum. Vaccine. 2000 Apr 03; 18(19):2033-8. PMID: 10706966.
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    67. Dereure J, Boni M, Pratlong F, el Hadi Osman M, Bucheton B, el-Safi S, Feugier E, Musa MK, Davoust B, Dessein A, Dedet JP. Visceral leishmaniasis in Sudan: first identifications of Leishmania from dogs. Trans R Soc Trop Med Hyg. 2000 Mar-Apr; 94(2):154-5. PMID: 10897352.
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    68. Abel L, Marquet S, Chevillard C, elWali NE, Hillaire D, Dessein A. [Genetic predisposition to bilharziasis in humans: research methods and application to the study of Schistosoma mansoni infection]. J Soc Biol. 2000; 194(1):15-8. PMID: 11107544.
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    69. Mary C, Auriault V, Faugère B, Dessein AJ. Control of Leishmania infantum infection is associated with CD8(+) and gamma interferon- and interleukin-5-producing CD4(+) antigen-specific T cells. Infect Immun. 1999 Nov; 67(11):5559-66. PMID: 10531200.
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    70. Mohamed-Ali Q, Elwali NE, Abdelhameed AA, Mergani A, Rahoud S, Elagib KE, Saeed OK, Abel L, Magzoub MM, Dessein AJ. Susceptibility to periportal (Symmers) fibrosis in human schistosoma mansoni infections: evidence that intensity and duration of infection, gender, and inherited factors are critical in disease progression. J Infect Dis. 1999 Oct; 180(4):1298-306. PMID: 10479161.
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    71. Dessein AJ, Hillaire D, Elwali NE, Marquet S, Mohamed-Ali Q, Mirghani A, Henri S, Abdelhameed AA, Saeed OK, Magzoub MM, Abel L. Severe hepatic fibrosis in Schistosoma mansoni infection is controlled by a major locus that is closely linked to the interferon-gamma receptor gene. Am J Hum Genet. 1999 Sep; 65(3):709-21. PMID: 10441577.
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    72. Rodrigues V, Piper K, Couissinier-Paris P, Bacelar O, Dessein H, Dessein AJ. Genetic control of schistosome infections by the SM1 locus of the 5q31-q33 region is linked to differentiation of type 2 helper T lymphocytes. Infect Immun. 1999 Sep; 67(9):4689-92. PMID: 10456917.
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    73. Dessein AJ, Marquet S, Henri S, El Wali NE, Hillaire D, Rodrigues V, Prata A, Ali QM, Gharib B, de Reggi M, Magzoub MM, Saeed OK, Abdelhameed AA, Abel L. Infection and disease in human schistosomiasis mansoni are under distinct major gene control. Microbes Infect. 1999 Jun; 1(7):561-7. PMID: 10603573.
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    74. Marquet S, Abel L, Hillaire D, Dessein A. Full results of the genome-wide scan which localises a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Eur J Hum Genet. 1999 Jan; 7(1):88-97. PMID: 10094195.
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    75. Argiro L, Henri S, Dessein H, Dessein AJ, Bourgois A. Induction of a protective immunity against Schistosoma mansoni with ovalbumin-coupled Sm37-5 coadsorbed with granulocyte-macrophage colony stimulating factor (GM-CSF) or IL-12 on alum. Vaccine. 1999 Jan; 17(1):13-8. PMID: 10078602.
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    76. Gallian P, Rodrigues V, Cantaloube JF, Dessein H, de Micco P, Dessein AJ, de Lamballerie X. High prevalence of GB-C/hepatitis G virus in a Brazilian population with helminth infection. J Med Virol. 1998 Dec; 56(4):310-5. PMID: 9829634.
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    77. Abel L, Dessein AJ. Genetic epidemiology of infectious diseases in humans: design of population-based studies. Emerg Infect Dis. 1998 Oct-Dec; 4(4):593-603. PMID: 9866735.
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    78. Garcia A, Marquet S, Bucheton B, Hillaire D, Cot M, Fievet N, Dessein AJ, Abel L. Linkage analysis of blood Plasmodium falciparum levels: interest of the 5q31-q33 chromosome region. Am J Trop Med Hyg. 1998 Jun; 58(6):705-9. PMID: 9660449.
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    79. Chiarella JM, Goldberg AC, Abel L, Carvalho EM, Kalil J, Dessein A. Absence of linkage between MHC and a gene involved in susceptibility to human schistosomiasis. Braz J Med Biol Res. 1998 May; 31(5):665-70. PMID: 9698772.
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    80. Granel B, Disdier P, Schleinitz N, Chevillard C, Harle JR, Dessein A, Weiller PJ. [Genetic control of hypereosinophilias]. Med Trop (Mars). 1998; 58(4 Suppl):508-11. PMID: 10410376.
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    81. Granel B, Serratrice J, Schleinitz N, Veit V, Swiader L, Disdier P, Harle JR, Dessein A, Weiller PJ. [Diagnostic approach to hypereosinophilia]. Med Trop (Mars). 1998; 58(4 Suppl):489-92. PMID: 10410372.
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    82. Abel L, Dessein AJ. The impact of host genetics on susceptibility to human infectious diseases. Curr Opin Immunol. 1997 Aug; 9(4):509-16. PMID: 9287190.
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    83. Kohlstädt S, Couissinier-Paris P, Bourgois A, Bouchon B, Piper K, Kolbe H, Dessein AJ. Characterization of a schistosome T cell-stimulating antigen (Sm10) associated with protective immunity in humans. Mol Biochem Parasitol. 1997 Feb; 84(2):155-65. PMID: 9084036.
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    84. Dessein A. [Genetic predisposition to infectious diseases]. Med Trop (Mars). 1997; 57(3 Suppl):10-2. PMID: 9513172.
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    85. Morton SM, Bocaccio I, Depetris D, Mattei M, Dessein A. Assignment of IL12RB2 to human chromosome 1p31.3-->p31.2 between D1S230 and D1S198. Cytogenet Cell Genet. 1997; 79(3-4):282-3. PMID: 9605872.
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    86. Marquet S, Abel L, Hillaire D, Dessein H, Kalil J, Feingold J, Weissenbach J, Dessein AJ. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet. 1996 Oct; 14(2):181-4. PMID: 8841190.
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    87. Rodrigues V, Abel L, Piper K, Dessein AJ. Segregation analysis indicates a major gene in the control of interleukine-5 production in humans infected with Schistosoma mansoni. Am J Hum Genet. 1996 Aug; 59(2):453-61. PMID: 8755934.
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    88. Couissinier-Paris P, Dessein AJ. Schistosoma-specific helper T cell clones from subjects resistant to infection by Schistosoma mansoni are Th0/2. Eur J Immunol. 1995 Aug; 25(8):2295-302. PMID: 7545117.
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    89. Couissinier-Paris P, Bourgois A, Dessein H, Bacellar O, Rodrigues V, Kohlstädt S, Buonavista N, Pène J, Dessein AJ. Identification of a major T cell immunogen in the anti-schistosome response of adult residents in an area endemic for Schistosoma mansoni. Eur J Immunol. 1995 Apr; 25(4):903-10. PMID: 7737292.
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    90. Hagan P, Chandiwana S, Ndhlovu P, Woolhouse M, Dessein A. The epidemiology, immunology and morbidity of Schistosoma haematobium infections in diverse communities in Zimbabwe. I. The study design. Trop Geogr Med. 1994; 46(4 Spec No):227-32. PMID: 7825225.
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    91. Demeure CE, Rihet P, Abel L, Ouattara M, Bourgois A, Dessein AJ. Resistance to Schistosoma mansoni in humans: influence of the IgE/IgG4 balance and IgG2 in immunity to reinfection after chemotherapy. J Infect Dis. 1993 Oct; 168(4):1000-8. PMID: 7690821.
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    92. de Jesus AM, Almeida RP, Bacellar O, Araujo MI, Demeure C, Bina JC, Dessein AJ, Carvalho EM. Correlation between cell-mediated immunity and degree of infection in subjects living in an endemic area of schistosomiasis. Eur J Immunol. 1993 Jan; 23(1):152-8. PMID: 8419165.
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    93. Rihet P, Demeure CE, Dessein AJ, Bourgois A. Strong serum inhibition of specific IgE correlated to competing IgG4, revealed by a new methodology in subjects from a S. mansoni endemic area. Eur J Immunol. 1992 Aug; 22(8):2063-70. PMID: 1639104.
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    94. Dessein AJ, Couissinier P, Demeure C, Rihet P, Kohlstaedt S, Carneiro-Carvalho D, Ouattara M, Goudot-Crozel V, Dessein H, Bourgois A, et al. Environmental, genetic and immunological factors in human resistance to Schistosoma mansoni. Immunol Invest. 1992 Aug; 21(5):423-53. PMID: 1428019.
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    95. Rihet P, Demeure CE, Bourgois A, Prata A, Dessein AJ. Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels. Eur J Immunol. 1991 Nov; 21(11):2679-86. PMID: 1936116.
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    96. Abel L, Demenais F, Prata A, Souza AE, Dessein A. Evidence for the segregation of a major gene in human susceptibility/resistance to infection by Schistosoma mansoni. Am J Hum Genet. 1991 May; 48(5):959-70. PMID: 1902058.
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    97. Abel L, Dessein A. Genetic predisposition to high infections in an endemic area of Schistosoma mansoni. Rev Soc Bras Med Trop. 1991 Jan-Mar; 24(1):1-3. PMID: 1815281.
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    98. Elsas MI, Dessein AJ, Elsas PX. Selection of U937 histiocytic lymphoma cells highly responsive to phorbol ester-induced differentiation using monoclonal antibody to the eosinophil cytotoxicity-enhancing factor. Blood. 1990 Jun 15; 75(12):2427-33. PMID: 2190641.
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    99. Elsas PX, Elsas MI, Dessein AJ. Eosinophil cytotoxicity enhancing factor: purification, characterization and immunocytochemical localization on the monocyte surface. Eur J Immunol. 1990 May; 20(5):1143-51. PMID: 2192904.
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    100. Goudot-Crozel V, Caillol D, Djabali M, Dessein AJ. The major parasite surface antigen associated with human resistance to schistosomiasis is a 37-kD glyceraldehyde-3P-dehydrogenase. J Exp Med. 1989 Dec 01; 170(6):2065-80. PMID: 2584935.
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    101. Dessein AJ, Begley M, Demeure C, Caillol D, Fueri J, dos Reis MG, Andrade ZA, Prata A, Bina JC. Human resistance to Schistosoma mansoni is associated with IgG reactivity to a 37-kDa larval surface antigen. J Immunol. 1988 Apr 15; 140(8):2727-36. PMID: 3128605.
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    102. Roubin R, Elsas PP, Fiers W, Dessein AJ. Recombinant human tumour necrosis factor (rTNF)2 enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187. Clin Exp Immunol. 1987 Nov; 70(2):484-90. PMID: 2827923.
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    103. Silberstein DS, Dessein AJ, Elsas PP, Fontaine B, David JR. Characterization of a factor from the U937 cell line that enhances the toxicity of human eosinophils to Schistosoma mansoni larvae. J Immunol. 1987 May 01; 138(9):3042-50. PMID: 3494778.
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    104. Elsas P, Lee TH, Lenzi HL, Dessein AJ. Monocytes activate eosinophils for enhanced helminthotoxicity and increased generation of leukotriene C4. Ann Inst Pasteur Immunol. 1987 Jan-Feb; 138(1):97-116. PMID: 3107591.
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    105. Kigoni EP, Elsas PP, Lenzi HL, Dessein AJ. IgE antibody and resistance to infection. II. Effect of IgE suppression on the early and late skin reaction and resistance of rats to Schistosoma mansoni infection. Eur J Immunol. 1986 Jun; 16(6):589-95. PMID: 3087755.
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    106. Dessein AJ, Lee TH, Elsas P, Ravalese J, Silberstein D, David JR, Austen KF, Lewis RA. Enhancement by monokines of leukotriene generation by human eosinophils and neutrophils stimulated with calcium ionophore A23187. J Immunol. 1986 May 15; 136(10):3829-38. PMID: 3009610.
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    107. Lenzi HL, Mednis AD, Dessein AJ. Activation of human eosinophils by monokines and lymphokines: source and biochemical characteristics of the eosinophil cytotoxicity-enhancing activity produced by blood mononuclear cells. Cell Immunol. 1985 Sep; 94(2):333-46. PMID: 3875417.
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    108. Caulfield JP, Lenzi HL, Elsas P, Dessein AJ. Ultrastructure of the attack of eosinophils stimulated by blood mononuclear cell products on schistosomula of Schistosoma mansoni. Am J Pathol. 1985 Sep; 120(3):380-90. PMID: 4037065.
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    109. Pincus SH, Dessein A, Lenzi H, Vadas MA, David J. Eosinophil-mediated killing of schistosomula of Schistosoma mansoni: oxidative requirement for enhancement by eosinophil colony stimulating factor (CSF-alpha) and supernatants with eosinophil cytotoxicity enhancing activity (E-CEA). Cell Immunol. 1984 Sep; 87(2):424-33. PMID: 6088087.
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    110. Dessein AJ, Lenzi HL, Bina JC, Carvalho EM, Weiser WY, Andrade ZA, David JR. Modulation of eosinophil cytotoxicity by blood mononuclear cells from healthy subjects and patients with chronic schistosomiasis mansoni. Cell Immunol. 1984 Apr 15; 85(1):100-13. PMID: 6713539.
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    111. Vadas MA, Varigos G, Nicola N, Pincus S, Dessein A, Metcalf D, Battye FL. Eosinophil activation by colony-stimulating factor in man: metabolic effects and analysis by flow cytometry. Blood. 1983 Jun; 61(6):1232-41. PMID: 6301584.
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    112. Dessein A, Butterworth AE, Vadas MA, David JR. Maturation in vivo of Schistosoma mansoni schistosomula after culture in vitro with granulocytes and antibody. Infect Immun. 1983 Jan; 39(1):225-32. PMID: 6822415.
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    113. Dessein AJ, Lenzi HL, David JR. Modulation of the cytotoxicity of human blood eosinophils by factors secreted by monocytes and T lymphocytes. Monogr Allergy. 1983; 18:45-51. PMID: 6358869.
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    114. Dessein AJ, Vadas MA, Nicola NA, Metcalf D, David JR. Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s). J Exp Med. 1982 Jul 01; 156(1):90-103. PMID: 6979609.
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    115. Butterworth AE, Taylor DW, Veith MC, Vadas MA, Dessein A, Sturrock RF, Wells E. Studies on the mechanisms of immunity in human schistosomiasis. Immunol Rev. 1982; 61:5-39. PMID: 6460684.
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    116. Vadas MA, Dessein A, Nicola N, David JR. In vitro enhancement of the helminthotoxic capacity of human blood eosinophils. Aust J Exp Biol Med Sci. 1981 Dec; 59(Pt 6):739-41. PMID: 6153062.
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    117. Dessein A, Samuelson JC, Butterworth AE, Hogan M, Sherry BA, Vadas MA, David JR. Immune evasion by Schistosoma mansoni: loss of susceptibility to antibody or complement-dependent eosinophil attack by schistosomula cultured in medium free of macromolecules. Parasitology. 1981 Jun; 82(Pt 3):357-74. PMID: 7243345.
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    118. Dessein AJ, Parker WL, James SL, David JR. IgE antibody and resistance to infection. I. Selective suppression of the IgE antibody response in rats diminishes the resistance and the eosinophil response to Trichinella spiralis infection. J Exp Med. 1981 Feb 01; 153(2):423-36. PMID: 6787166.
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    119. Vadas MA, Butterworth AE, Sherry B, Dessein A, Hogan M, Bout D, David JR. Interactions between human eosinophils and schistosomula of Schistosoma mansoni. I. Stable and irreversible antibody-dependent adherence. J Immunol. 1980 Mar; 124(3):1441-8. PMID: 6153682.
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    120. Dessein A, Ju ST, Dorf ME, Benacerraf B, Germain RN. IgE response to synthetic polypeptide antigens. II. Idiotypic analysis of the IgE response to L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). J Immunol. 1980 Jan; 124(1):71-6. PMID: 6153108.
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    121. Butterworth AE, Vadas MA, Wassom DL, Dessein A, Hogan M, Sherry B, Gleich GJ, David JR. Interactions between human eosinophils and schistosomula of Schistosoma mansoni. II. The mechanism of irreversible eosinophil adherence. J Exp Med. 1979 Dec 01; 150(6):1456-71. PMID: 390086.
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    122. Dessein A, Germain RN, Dorf ME, Benacerraf B. IgE responses to synthetic polypeptide antigens. I. Simultaneous Ir gene and isotype-specific regulation of IgE responses to L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). J Immunol. 1979 Jul; 123(1):463-70. PMID: 109538.
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    123. Waltenbaugh C, Dessein A, Benacerraf B. Characterization of the primary IgM response to GAT and GT: conditions required for the detection of IgM antibodies. J Immunol. 1979 Jan; 122(1):27-33. PMID: 84020.
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