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Professor Stefan Kaufmann

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kaufmann SHE. Indole Propionic Acid: a Small Molecule Links between Gut Microbiota and Tuberculosis. Antimicrob Agents Chemother. 2018 May; 62(5). PMID: 29700005.
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    2. Bénard A, Sakwa I, Schierloh P, Colom A, Mercier I, Tailleux L, Jouneau L, Boudinot P, Al-Saati T, Lang R, Rehwinkel J, Loxton AG, Kaufmann SHE, Anton-Leberre V, O'Garra A, Sasiain MDC, Gicquel B, Fillatreau S, Neyrolles O, Hudrisier D. B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis. Am J Respir Crit Care Med. 2018 Mar 15; 197(6):801-813. PMID: 29161093.
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    3. Ahsan F, Maertzdorf J, Guhlich-Bornhof U, Kaufmann SHE, Moura-Alves P. IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis. Sci Rep. 2018 Jan 24; 8(1):1520. PMID: 29367626.
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    4. Dong Z, Shi J, Dorhoi A, Zhang J, Soodeen-Lalloo AK, Tan W, Yin H, Sha W, Li W, Zheng R, Liu Z, Yang H, Qin L, Wang J, Huang X, Wu C, Kaufmann SHE, Feng Y. Hemostasis and Lipoprotein Indices Signify Exacerbated Lung Injury in TB With Diabetes Comorbidity. Chest. 2017 Dec 07. PMID: 29224833.
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    5. Domaszewska T, Scheuermann L, Hahnke K, Mollenkopf H, Dorhoi A, Kaufmann SHE, Weiner J. Concordant and discordant gene expression patterns in mouse strains identify best-fit animal model for human tuberculosis. Sci Rep. 2017 Sep 21; 7(1):12094. PMID: 28935874.
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    6. Gengenbacher M, Duque-Correa MA, Kaiser P, Schuerer S, Lazar D, Zedler U, Reece ST, Nayyar A, Cole ST, Makarov V, Barry Iii CE, Dartois V, Kaufmann SHE. NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans. Sci Rep. 2017 Aug 18; 7(1):8853. PMID: 28821804.
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    7. Perdomo C, Zedler U, Kühl AA, Lozza L, Saikali P, Sander LE, Vogelzang A, Kaufmann SH, Kupz A. Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis. MBio. 2016 11 22; 7(6). PMID: 27879332.
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    8. Vogelzang A, Lozza L, Reece ST, Perdomo C, Zedler U, Hahnke K, Oberbeck-Mueller D, Dorhoi A, Kaufmann SH. Neonatal Fc Receptor Regulation of Lung Immunoglobulin and CD103+ Dendritic Cells Confers Transient Susceptibility to Tuberculosis. Infect Immun. 2016 10; 84(10):2914-21. PMID: 27481246.
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    9. Kaufmann SH, Fortune S, Pepponi I, Ruhwald M, Schrager LK, Ottenhoff TH. TB biomarkers, TB correlates and human challenge models: New tools for improving assessment of new TB vaccines. Tuberculosis (Edinb). 2016 08; 99 Suppl 1:S8-S11. PMID: 27402312.
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    10. Gengenbacher M, Nieuwenhuizen N, Vogelzang A, Liu H, Kaiser P, Schuerer S, Lazar D, Wagner I, Mollenkopf HJ, Kaufmann SH. Deletion of nuoG from the Vaccine Candidate Mycobacterium bovis BCG ?ureC::hly Improves Protection against Tuberculosis. MBio. 2016 05 24; 7(3). PMID: 27222470.
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    11. Kaufmann SH. EFIS lecture. Immune response to tuberculosis: How to control the most successful pathogen on earth. Immunol Lett. 2016 07; 175:50-7. PMID: 27181094.
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    12. Gengenbacher M, Kaiser P, Schuerer S, Lazar D, Kaufmann SH. Post-exposure vaccination with the vaccine candidate Bacillus Calmette-Guérin ?ureC::hly induces superior protection in a mouse model of subclinical tuberculosis. Microbes Infect. 2016 05; 18(5):364-8. PMID: 26994939.
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    13. Kaufmann SHE, Dorhoi A. Molecular Determinants in Phagocyte-Bacteria Interactions. Immunity. 2016 Mar 15; 44(3):476-491. PMID: 26982355.
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    14. Kaufmann SH. Immunopathology of mycobacterial diseases. Semin Immunopathol. 2016 Mar; 38(2):135-8. PMID: 26837757.
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    15. Maertzdorf J, McEwen G, Weiner J, Tian S, Lader E, Schriek U, Mayanja-Kizza H, Ota M, Kenneth J, Kaufmann SH. Concise gene signature for point-of-care classification of tuberculosis. EMBO Mol Med. 2016 Feb 01; 8(2):86-95. PMID: 26682570.
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    16. Dorhoi A, Kaufmann SH. Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis. Semin Immunopathol. 2016 Mar; 38(2):153-66. PMID: 26438324.
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    17. Esterhuyse MM, Weiner J, Caron E, Loxton AG, Iannaccone M, Wagman C, Saikali P, Stanley K, Wolski WE, Mollenkopf HJ, Schick M, Aebersold R, Linhart H, Walzl G, Kaufmann SH. Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers. MBio. 2015 Sep 15; 6(5):e01187-15. PMID: 26374119.
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    18. Weiner J, Kaufmann SH, Maertzdorf J. High-throughput data analysis and data integration for vaccine trials. Vaccine. 2015 Sep 29; 33(40):5249-55. PMID: 25976544.
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    19. Kaufmann SH, Fletcher HA, Guzmán CA, Ottenhoff TH. Big Data in Vaccinology: Introduction and section summaries. Vaccine. 2015 Sep 29; 33(40):5237-40. PMID: 25939278.
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    20. Kaufmann SH. Aeras-sponsored meeting reports: Aerosol TB vaccines, whole mycobacteria cell TB vaccines, and prevention of sustained Mycobacterium tuberculosis infection. Vaccine. 2015 Jun 12; 33(26):3035-7. PMID: 25863114.
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    21. Maertzdorf J, Kaufmann SH, Weiner J. Molecular signatures for vaccine development. Vaccine. 2015 Sep 29; 33(40):5256-61. PMID: 25858856.
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    22. Kaufmann SH, Evans TG, Hanekom WA. Tuberculosis vaccines: time for a global strategy. Sci Transl Med. 2015 Feb 25; 7(276):276fs8. PMID: 25717094.
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    23. Rienksma RA, Suarez-Diez M, Mollenkopf HJ, Dolganov GM, Dorhoi A, Schoolnik GK, Martins Dos Santos VA, Kaufmann SH, Schaap PJ, Gengenbacher M. Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing. BMC Genomics. 2015 Feb 05; 16:34. PMID: 25649146.
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    24. Dorhoi A, Kaufmann SH. Perspectives on host adaptation in response to Mycobacterium tuberculosis: modulation of inflammation. Semin Immunol. 2014 Dec; 26(6):533-42. PMID: 25453228.
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    25. Kaufmann SH. Introduction. Semin Immunol. 2014 Dec; 26(6):429-30. PMID: 25459522.
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    26. Duque-Correa MA, Kühl AA, Rodriguez PC, Zedler U, Schommer-Leitner S, Rao M, Weiner J, Hurwitz R, Qualls JE, Kosmiadi GA, Murray PJ, Kaufmann SH, Reece ST. Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):E4024-32. PMID: 25201986.
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    27. Dutruel C, Thole J, Geels M, Mollenkopf HJ, Ottenhoff T, Guzman CA, Fletcher HA, Leroy O, Kaufmann SH. TRANSVAC workshop on standardisation and harmonisation of analytical platforms for HIV, TB and malaria vaccines: 'how can big data help?'. Vaccine. 2014 Jul 31; 32(35):4365-8. PMID: 24950356.
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    28. Gengenbacher M, Vogelzang A, Schuerer S, Lazar D, Kaiser P, Kaufmann SH. Dietary pyridoxine controls efficacy of vitamin B6-auxotrophic tuberculosis vaccine bacillus Calmette-Guérin ?ureC::hly ?pdx1 in mice. MBio. 2014 Jun 03; 5(3):e01262-14. PMID: 24895310.
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    29. Dorhoi A, Kaufmann SH. Tumor necrosis factor alpha in mycobacterial infection. Semin Immunol. 2014 Jun; 26(3):203-9. PMID: 24819298.
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    30. Iannaccone M, Dorhoi A, Kaufmann SH. Host-directed therapy of tuberculosis: what is in it for microRNA? Expert Opin Ther Targets. 2014 May; 18(5):491-4. PMID: 24641181.
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    31. Kaufmann SH, McElrath MJ, Lewis DJ, Del Giudice G. Challenges and responses in human vaccine development. Curr Opin Immunol. 2014 Jun; 28:18-26. PMID: 24561742.
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    32. Kaufmann SH, Dorhoi A. Inflammation in tuberculosis: interactions, imbalances and interventions. Curr Opin Immunol. 2013 Aug; 25(4):441-9. PMID: 23725875.
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    33. Kaufmann SH. Tuberculosis vaccines: time to think about the next generation. Semin Immunol. 2013 Apr; 25(2):172-81. PMID: 23706597.
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    34. Kaufmann SH, Gengenbacher M. Recombinant live vaccine candidates against tuberculosis. Curr Opin Biotechnol. 2012 Dec; 23(6):900-7. PMID: 22483201.
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    35. Desel C, Dorhoi A, Bandermann S, Grode L, Eisele B, Kaufmann SH. Recombinant BCG ?ureC hly+ induces superior protection over parental BCG by stimulating a balanced combination of type 1 and type 17 cytokine responses. J Infect Dis. 2011 Nov 15; 204(10):1573-84. PMID: 21933877.
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    36. Kaufmann SH. Intracellular pathogens: living in an extreme environment. Immunol Rev. 2011 Mar; 240(1):5-10. PMID: 21349082.
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    37. Kaufmann SH. Future vaccination strategies against tuberculosis: thinking outside the box. Immunity. 2010 Oct 29; 33(4):567-77. PMID: 21029966.
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    38. Kaufmann SH, Hussey G, Lambert PH. New vaccines for tuberculosis. Lancet. 2010 Jun 12; 375(9731):2110-9. PMID: 20488515.
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    39. Kaufmann SH. Novel tuberculosis vaccination strategies based on understanding the immune response. J Intern Med. 2010 Apr; 267(4):337-53. PMID: 20433580.
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    40. Kaufmann SH, Meinke AL, von Gabain A. [Novel vaccination concepts on the basis of modern insights into immunology]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 Nov; 52(11):1069-82. PMID: 19838650.
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    41. Kaufmann SH. Elie Metchnikoff's and Paul Ehrlich's impact on infection biology. Microbes Infect. 2008 Nov-Dec; 10(14-15):1417-9. PMID: 18824243.
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    42. Kaufmann SH. Rational design of novel antibacterial vaccines with an emphasis on tuberculosis. Scand J Infect Dis. 2008; 40(8):595-600. PMID: 18979596.
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    43. Kaufmann SH. The contribution of immunology to the rational design of novel antibacterial vaccines. Nat Rev Microbiol. 2007 Jul; 5(7):491-504. PMID: 17558425.
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    44. Kaufmann SH, Parida SK. Changing funding patterns in tuberculosis. Nat Med. 2007 Mar; 13(3):299-303. PMID: 17342144.
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    45. Kaufmann SH, Baumann S, Nasser Eddine A. Exploiting immunology and molecular genetics for rational vaccine design against tuberculosis. Int J Tuberc Lung Dis. 2006 Oct; 10(10):1068-79. PMID: 17044198.
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    46. Kaufmann SH. Envisioning future strategies for vaccination against tuberculosis. Nat Rev Immunol. 2006 09; 6(9):699-704. PMID: 16917508.
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    47. Kaufmann SH, Winau F. From bacteriology to immunology: the dualism of specificity. Nat Immunol. 2005 Nov; 6(11):1063-6. PMID: 16239917.
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    48. Kaufmann SH. Recent findings in immunology give tuberculosis vaccines a new boost. Trends Immunol. 2005 Dec; 26(12):660-7. PMID: 16246622.
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    49. Kaufmann SH, Schaible UE. 100th anniversary of Robert Koch's Nobel Prize for the discovery of the tubercle bacillus. Trends Microbiol. 2005 Oct; 13(10):469-75. PMID: 16112578.
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    50. Kaufmann SH, McMichael AJ. Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis. Nat Med. 2005 Apr; 11(4 Suppl):S33-44. PMID: 15812488.
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    51. Kaufmann SH, Schaible UE. Antigen presentation and recognition in bacterial infections. Curr Opin Immunol. 2005 Feb; 17(1):79-87. PMID: 15653315.
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    52. Kaufmann SH. New issues in tuberculosis. Ann Rheum Dis. 2004 Nov; 63 Suppl 2:ii50-ii56. PMID: 15479872.
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    53. Kaufmann SH, Mittrücker HW. Vaccination against tuberculosis: current status and future promise. Semin Respir Crit Care Med. 2004 Jun; 25(3):345-52. PMID: 16088475.
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    54. Kaufmann SH, Schaible UE. A dangerous liaison between two major killers: Mycobacterium tuberculosis and HIV target dendritic cells through DC-SIGN. J Exp Med. 2003 Jan 06; 197(1):1-5. PMID: 12515808.
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    55. Kaufmann SH. Immune response to tuberculosis: experimental animal models. Tuberculosis (Edinb). 2003; 83(1-3):107-11. PMID: 12758198.
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    56. Kaufmann SH. Protection against tuberculosis: cytokines, T cells, and macrophages. Ann Rheum Dis. 2002 Nov; 61 Suppl 2:ii54-8. PMID: 12379623.
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    57. Kaufmann SH, Raupach B, Finlay BB. Introduction: microbiology and immunology: lessons learned from Salmonella. Microbes Infect. 2001 Nov-Dec; 3(14-15):1177-81. PMID: 11755405.
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    58. Kaufmann SH. How can immunology contribute to the control of tuberculosis? Nat Rev Immunol. 2001 Oct; 1(1):20-30. PMID: 11905811.
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    59. Kaufmann SH, Hess J. Immune response against Mycobacterium tuberculosis: implications for vaccine development. J Biotechnol. 2000 Sep 29; 83(1-2):13-7. PMID: 11000454.
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    60. Kaufmann SH. Is the development of a new tuberculosis vaccine possible? Nat Med. 2000 Sep; 6(9):955-60. PMID: 10973302.
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    61. Kaufmann SH, Fensterle J, Hess J. The need for a novel generation of vaccines. Immunobiology. 1999 Dec; 201(2):272-82. PMID: 10631576.
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    62. Kaufmann SH. Cell-mediated immunity: dealing a direct blow to pathogens. Curr Biol. 1999 Feb 11; 9(3):R97-9. PMID: 10021381.
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    63. Kaufmann SH. Killing vs suicide in antibacterial defence. Trends Microbiol. 1999 Feb; 7(2):59-61. PMID: 10081080.
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    64. Kaufmann SH, Hess J. Impact of intracellular location of and antigen display by intracellular bacteria: implications for vaccine development. Immunol Lett. 1999 Jan; 65(1-2):81-4. PMID: 10065631.
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    65. Kaufmann SH. [Immunologic foundations of new vaccination strategies]. Naturwissenschaften. 1998 Feb; 85(2):62-72. PMID: 9530641.
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    66. Kaufmann SH, Doherty PC. Immunity to infection. Curr Opin Immunol. 1997 Aug; 9(4):453-5. PMID: 9287182.
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