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Dr Maria Adelaida Gomez

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Barrera MC, Rojas LJ, Weiss A, Fernandez O, McMahon-Pratt D, Saravia NG, Gomez MA. Profiling gene expression of antimony response genes in Leishmania (Viannia) panamensis and infected macrophages and its relationship with drug susceptibility. Acta Trop. 2017 Aug 24; 176:355-363. PMID: 28843396.
      View in: PubMed
    2. Dohmen LC, Navas A, Vargas DA, Gregory DJ, Kip A, Dorlo TP, Gomez MA. Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS. J Biol Chem. 2016 Apr 29; 291(18):9638-47. PMID: 26903515; PMCID: PMC4850301 [Available on 04/29/17].
    3. Rosales-Chilama M, Gongora RE, Valderrama L, Jojoa J, Alexander N, Rubiano LC, Cossio A, Adams ER, Saravia NG, Gomez MA. Parasitological Confirmation and Analysis of Leishmania Diversity in Asymptomatic and Subclinical Infection following Resolution of Cutaneous Leishmaniasis. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004273. PMID: 26659114; PMCID: PMC4684356.
    4. Kip AE, Rosing H, Hillebrand MJ, Castro MM, Gomez MA, Schellens JH, Beijnen JH, Dorlo TP. Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 15; 998-999:57-62. PMID: 26160472; PMCID: PMC4654404.
    5. Moreno M, Ferro C, Rosales-Chilama M, Rubiano L, Delgado M, Cossio A, Gómez MA, Ocampo C, Saravia NG. First report of Warileya rotundipennis (Psychodidae: Phlebotominae) naturally infected with Leishmania (Viannia) in a focus of cutaneous leishmaniasis in Colombia. Acta Trop. 2015 Aug; 148:191-6. PMID: 25917717; PMCID: PMC4654406.
    6. Adams ER, Gomez MA, Scheske L, Rios R, Marquez R, Cossio A, Albertini A, Schallig H, Saravia NG. Sensitive diagnosis of cutaneous leishmaniasis by lesion swab sampling coupled to qPCR. Parasitology. 2014 Dec; 141(14):1891-7. PMID: 25111885; PMCID: PMC4654403.
    7. Fernández OL, Diaz-Toro Y, Ovalle C, Valderrama L, Muvdi S, Rodríguez I, Gomez MA, Saravia NG. Miltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in Colombia. PLoS Negl Trop Dis. 2014 May; 8(5):e2871. PMID: 24853871; PMCID: PMC4031164.
    8. Navas A, Vargas DA, Freudzon M, McMahon-Pratt D, Saravia NG, Gómez MA. Chronicity of dermal leishmaniasis caused by Leishmania panamensis is associated with parasite-mediated induction of chemokine gene expression. Infect Immun. 2014 Jul; 82(7):2872-80. PMID: 24752514; PMCID: PMC4097649.
    9. Obonaga R, Fernández OL, Valderrama L, Rubiano LC, Castro Mdel M, Barrera MC, Gomez MA, Gore Saravia N. Treatment failure and miltefosine susceptibility in dermal leishmaniasis caused by Leishmania subgenus Viannia species. Antimicrob Agents Chemother. 2014; 58(1):144-52. PMID: 24145529; PMCID: PMC3910710.
    10. Gómez MA, Navas A, Márquez R, Rojas LJ, Vargas DA, Blanco VM, Koren R, Zilberstein D, Saravia NG. Leishmania panamensis infection and antimonial drugs modulate expression of macrophage drug transporters and metabolizing enzymes: impact on intracellular parasite survival. J Antimicrob Chemother. 2014 Jan; 69(1):139-49. PMID: 23975742; PMCID: PMC3861331.
    11. Walker J, Gongora R, Vasquez JJ, Drummelsmith J, Burchmore R, Roy G, Ouellette M, Gomez MA, Saravia NG. Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis. Mol Biochem Parasitol. 2012 Jun; 183(2):166-76. PMID: 22449941.
      View in: PubMed
    12. Shio MT, Hassani K, Isnard A, Ralph B, Contreras I, Gomez MA, Abu-Dayyeh I, Olivier M. Host cell signalling and leishmania mechanisms of evasion. J Trop Med. 2012; 2012:819512. PMID: 22131998; PMCID: PMC3216306.
    13. Santaella J, Ocampo CB, Saravia NG, Méndez F, Góngora R, Gomez MA, Munstermann LE, Quinnell RJ. Leishmania (Viannia) infection in the domestic dog in Chaparral, Colombia. Am J Trop Med Hyg. 2011 May; 84(5):674-80. PMID: 21540374; PMCID: PMC3083732.
    14. Gallego C, Golenbock D, Gomez MA, Saravia NG. Toll-like receptors participate in macrophage activation and intracellular control of Leishmania (Viannia) panamensis. Infect Immun. 2011 Jul; 79(7):2871-9. PMID: 21518783; PMCID: PMC3191987.
    15. Jaramillo M, Gomez MA, Larsson O, Shio MT, Topisirovic I, Contreras I, Luxenburg R, Rosenfeld A, Colina R, McMaster RW, Olivier M, Costa-Mattioli M, Sonenberg N. Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. Cell Host Microbe. 2011 Apr 21; 9(4):331-41. PMID: 21501832.
      View in: PubMed
    16. Gómez MA, Olivier M. Proteases and phosphatases during Leishmania-macrophage interaction: paving the road for pathogenesis. Virulence. 2010 Jul-Aug; 1(4):314-8. PMID: 21178462.
      View in: PubMed
    17. Gomez MA, Alisaraie L, Shio MT, Berghuis AM, Lebrun C, Gautier-Luneau I, Olivier M. Protein tyrosine phosphatases are regulated by mononuclear iron dicitrate. J Biol Chem. 2010 Aug 06; 285(32):24620-8. PMID: 20519508; PMCID: PMC2915698.
    18. Gomez MA, Contreras I, Hallé M, Tremblay ML, McMaster RW, Olivier M. Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases. Sci Signal. 2009 Sep 29; 2(90):ra58. PMID: 19797268.
      View in: PubMed
    19. Hallé M, Gomez MA, Stuible M, Shimizu H, McMaster WR, Olivier M, Tremblay ML. The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation. J Biol Chem. 2009 Mar 13; 284(11):6893-908. PMID: 19064994; PMCID: PMC2652307.
    20. Gomez MA, Li S, Tremblay ML, Olivier M. NRAMP-1 expression modulates protein-tyrosine phosphatase activity in macrophages: impact on host cell signaling and functions. J Biol Chem. 2007 Dec 14; 282(50):36190-8. PMID: 17942403.
      View in: PubMed
    21. Fotie J, Bohle DS, Olivier M, Adelaida Gomez M, Nzimiro S. Trypanocidal and antileishmanial dihydrochelerythrine derivatives from Garcinia lucida. J Nat Prod. 2007 Oct; 70(10):1650-3. PMID: 17880175.
      View in: PubMed
    22. Walker J, Vasquez JJ, Gomez MA, Drummelsmith J, Burchmore R, Girard I, Ouellette M. Identification of developmentally-regulated proteins in Leishmania panamensis by proteome profiling of promastigotes and axenic amastigotes. Mol Biochem Parasitol. 2006 May; 147(1):64-73. PMID: 16530278.
      View in: PubMed
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