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Dr Thomas Rea

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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Teles RMB, Kelly-Scumpia KM, Sarno EN, Rea TH, Ochoa MT, Cheng G, Modlin RL. IL-27 Suppresses Antimicrobial Activity in Human Leprosy. J Invest Dermatol. 2015 Oct; 135(10):2410-2417. PMID: 26030183.
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    2. Kamath S, Vaccaro SA, Rea TH, Ochoa MT. Recognizing and managing the immunologic reactions in leprosy. J Am Acad Dermatol. 2014 Oct; 71(4):795-803. PMID: 24767732.
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    3. Phelps R, Dumas F, Maynard C, Silver J, Rea T. Cerebral Performance Category and long-term prognosis following out-of-hospital cardiac arrest. Crit Care Med. 2013 May; 41(5):1252-7. PMID: 23388519.
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    4. Roosta N, Black DS, Rea TH. A comparison of stigma among patients with leprosy in rural Tanzania and urban United States: a role for public health in dermatology. Int J Dermatol. 2013 Apr; 52(4):432-40. PMID: 23451850.
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    5. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22; 339(6126):1448-53. PMID: 23449998.
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    6. Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ. Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis. 2013 Mar 15; 207(6):947-56. PMID: 23255567.
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    7. Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med. 2012 Mar 25; 18(4):555-63. PMID: 22447076.
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    8. Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL. MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nat Med. 2012 Jan 29; 18(2):267-73. PMID: 22286305.
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    9. Ochoa MT, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ. A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy. Immunology. 2010 Nov; 131(3):405-14. PMID: 20561085.
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    10. Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL. Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis. 2010 Feb 15; 201(4):558-69. PMID: 20070238.
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    11. Rea TH. Latapi's lepromatosis (Lucio's leprosy) without Lucio's phenomenon in a pubertal boy. Lepr Rev. 2009 Dec; 80(4):445-7. PMID: 20306644.
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    12. Monot M, Honoré N, Garnier T, Zidane N, Sherafi D, Paniz-Mondolfi A, Matsuoka M, Taylor GM, Donoghue HD, Bouwman A, Mays S, Watson C, Lockwood D, Khamesipour A, Khamispour A, Dowlati Y, Jianping S, Rea TH, Vera-Cabrera L, Stefani MM, Banu S, Macdonald M, Sapkota BR, Spencer JS, Thomas J, Harshman K, Singh P, Busso P, Gattiker A, Rougemont J, Brennan PJ, Cole ST. Comparative genomic and phylogeographic analysis of Mycobacterium leprae. Nat Genet. 2009 Dec; 41(12):1282-9. PMID: 19881526.
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    13. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe. 2009 Oct 22; 6(4):343-53. PMID: 19837374.
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    14. Tanaka M, Krutzik SR, Sieling PA, Lee DJ, Rea TH, Modlin RL. Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. J Immunol. 2009 Aug 15; 183(4):2349-55. PMID: 19635920.
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    15. Cruz D, Watson AD, Miller CS, Montoya D, Ochoa MT, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner J, Modlin RL. Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest. 2008 Aug; 118(8):2917-28. PMID: 18636118.
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    16. Sieling PA, Hill PJ, Dobos KM, Brookman K, Kuhlman AM, Fabri M, Krutzik SR, Rea TH, Heaslip DG, Belisle JT, Modlin RL. Conserved mycobacterial lipoglycoproteins activate TLR2 but also require glycosylation for MHC class II-restricted T cell activation. J Immunol. 2008 May 01; 180(9):5833-42. PMID: 18424702.
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    17. Lee DJ, Sieling PA, Ochoa MT, Krutzik SR, Guo B, Hernandez M, Rea TH, Cheng G, Colonna M, Modlin RL. LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells. J Immunol. 2007 Dec 15; 179(12):8128-36. PMID: 18056355.
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    18. Bhandarkar SS, Cohen C, Kuruvila M, Rea TH, Mackelfresh JB, Lee DJ, Modlin RL, Arbiser JL. Angiogenesis in cutaneous lesions of leprosy: implications for treatment. Arch Dermatol. 2007 Dec; 143(12):1527-9. PMID: 18087002.
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    19. Martiniuk F, Rao SD, Rea TH, Glickman MS, Giovinazzo J, Rom WN, Cabrera A, Levis WR. Leprosy as immune reconstitution inflammatory syndrome in HIV-positive persons. Emerg Infect Dis. 2007 Sep; 13(9):1438-40. PMID: 18252138.
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    20. Niazi KR, Ochoa MT, Sieling PA, Rooke NE, Peter AK, Mollahan P, Dickey M, Rabizadeh S, Rea TH, Modlin RL. Activation of human CD4+ T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences. Immunology. 2007 Dec; 122(4):522-31. PMID: 17635609.
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    21. Sieling PA, Legaspi A, Ochoa MT, Rea TH, Modlin RL. Regulation of human T-cell homing receptor expression in cutaneous bacterial infection. Immunology. 2007 Apr; 120(4):518-25. PMID: 17343614.
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    22. Sabet S, Ochoa MT, Sieling PA, Rea TH, Modlin RL. Functional characterization of a T-cell receptor BV6+ T-cell clone derived from a leprosy lesion. Immunology. 2007 Mar; 120(3):354-61. PMID: 17140401.
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    23. Rea TH, Jerskey RS. Clinical and histologic variations among thirty patients with Lucio's phenomenon and pure and primitive diffuse lepromatosis (Latapi's lepromatosis). Int J Lepr Other Mycobact Dis. 2005 Sep; 73(3):169-88. PMID: 16830639.
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    24. Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med. 2005 Jun; 11(6):653-60. PMID: 15880118.
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    25. Sieling PA, Torrelles JB, Stenger S, Chung W, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Porcelli SA, Modlin RL. The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens. J Immunol. 2005 Mar 01; 174(5):2637-44. PMID: 15728470.
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    26. Hunger RE, Sieling PA, Ochoa MT, Sugaya M, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Blauvelt A, Porcelli SA, Modlin RL. Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. J Clin Invest. 2004 Mar; 113(5):701-8. PMID: 14991068.
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    27. Rea TH. Reversal reaction occurring 16 years after beginning antibacterial treatment. Lepr Rev. 2004 Mar; 75(1):86-90. PMID: 15072130.
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    28. Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, Modlin RL. Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science. 2003 Sep 12; 301(5639):1527-30. PMID: 12970564.
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    29. Krutzik SR, Ochoa MT, Sieling PA, Uematsu S, Ng YW, Legaspi A, Liu PT, Cole ST, Godowski PJ, Maeda Y, Sarno EN, Norgard MV, Brennan PJ, Akira S, Rea TH, Modlin RL. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med. 2003 May; 9(5):525-32. PMID: 12692544.
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    30. Oliveira RB, Ochoa MT, Sieling PA, Rea TH, Rambukkana A, Sarno EN, Modlin RL. Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy. Infect Immun. 2003 Mar; 71(3):1427-33. PMID: 12595460.
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    31. Rea TH. Elevated platelet counts and thrombocytosis in erythema nodosum leprosum. Int J Lepr Other Mycobact Dis. 2002 Sep; 70(3):167-73. PMID: 12483964.
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    32. Sieling PA, Jullien D, Dahlem M, Tedder TF, Rea TH, Modlin RL, Porcelli SA. CD1 expression by dendritic cells in human leprosy lesions: correlation with effective host immunity. J Immunol. 1999 Feb 01; 162(3):1851-8. PMID: 9973451.
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    33. Rea TH. The anatomic site of vascular injury in mouse skin exposed to ultraviolet light. J Invest Dermatol. 1968 Aug; 51(2):100-7. PMID: 5734567.
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