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Professor Jaime Alfredo Costales

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ramírez JC, Cura CI, da Cruz Moreira O, Lages-Silva E, Juiz N, Velázquez E, Ramírez JD, Alberti A, Pavia P, Flores-Chávez MD, Muñoz-Calderón A, Pérez-Morales D, Santalla J, Marcos da Matta Guedes P, Peneau J, Marcet P, Padilla C, Cruz-Robles D, Valencia E, Crisante GE, Greif G, Zulantay I, Costales JA, Alvarez-Martínez M, Martínez NE, Villarroel R, Villarroel S, Sánchez Z, Bisio M, Parrado R, Maria da Cunha Galvão L, Jácome da Câmara AC, Espinoza B, Alarcón de Noya B, Puerta C, Riarte A, Diosque P, Sosa-Estani S, Guhl F, Ribeiro I, Aznar C, Britto C, Yadón ZE, Schijman AG. Analytical Validation of Quantitative Real-Time PCR Methods for Quantification of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients. J Mol Diagn. 2015 Sep; 17(5):605-15. PMID: 26320872.
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    2. Costales JA, Kotton CN, Zurita-Leal AC, Garcia-Perez J, Llewellyn MS, Messenger LA, Bhattacharyya T, Burleigh BA. Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM). Parasit Vectors. 2015 Aug 25; 8:435. PMID: 26303927.
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    3. Costales JA, Jara-Palacios MA, Llewellyn MS, Messenger LA, Ocaña-Mayorga S, Villacís AG, Tibayrenc M, Grijalva MJ. Trypanosoma cruzi population dynamics in the Central Ecuadorian Coast. Acta Trop. 2015 Nov; 151:88-93. PMID: 26200787.
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    4. Costales JA, Sánchez-Gómez A, Silva-Aycaguer LC, Cevallos W, Tamayo S, Yumiseva CA, Jacobson JO, Martini L, Carrera CA, Grijalva MJ. A national survey to determine prevalence of Trypanosoma cruzi infection among pregnant women in Ecuador. Am J Trop Med Hyg. 2015 Apr; 92(4):807-10. PMID: 25667052.
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    5. Bhattacharyya T, Falconar AK, Luquetti AO, Costales JA, Grijalva MJ, Lewis MD, Messenger LA, Tran TT, Ramirez JD, Guhl F, Carrasco HJ, Diosque P, Garcia L, Litvinov SV, Miles MA. Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition. PLoS Negl Trop Dis. 2014 May; 8(5):e2892. PMID: 24852444.
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    6. Sánchez-Gómez A, Grijalva MJ, Silva-Aycaguer LC, Tamayo S, Yumiseva CA, Costales JA, Jacobson JO, Chiriboga M, Champutiz E, Mosquera C, Larrea M, Cevallos W. HIV and syphilis infection in pregnant women in Ecuador: prevalence and characteristics of antenatal care. Sex Transm Infect. 2014 Feb; 90(1):70-5. PMID: 24282329.
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    7. Mott GA, Costales JA, Burleigh BA. A soluble factor from Trypanosoma cruzi inhibits transforming growth factor-ß-induced MAP kinase activation and gene expression in dermal fibroblasts. PLoS One. 2011; 6(9):e23482. PMID: 21931601.
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    8. Ocaña-Mayorga S, Llewellyn MS, Costales JA, Miles MA, Grijalva MJ. Sex, subdivision, and domestic dispersal of Trypanosoma cruzi lineage I in southern Ecuador. PLoS Negl Trop Dis. 2010 Dec 14; 4(12):e915. PMID: 21179502.
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    9. Black CL, Ocaña-Mayorga S, Riner DK, Costales JA, Lascano MS, Arcos-Terán L, Preisser JS, Seed JR, Grijalva MJ. Seroprevalence of Trypanosoma cruzi in rural Ecuador and clustering of seropositivity within households. Am J Trop Med Hyg. 2009 Dec; 81(6):1035-40. PMID: 19996434.
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    10. Costales JA, Daily JP, Burleigh BA. Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling. BMC Genomics. 2009 May 29; 10:252. PMID: 19480704.
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    11. Mott A, Lenormand G, Costales J, Fredberg JJ, Burleigh BA. Modulation of host cell mechanics by Trypanosoma cruzi. J Cell Physiol. 2009 Feb; 218(2):315-22. PMID: 18853412.
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    12. Costales J, Rowland EC. A role for protease activity and host-cell permeability during the process of Trypanosoma cruzi egress from infected cells. J Parasitol. 2007 Dec; 93(6):1350-9. PMID: 18314679.
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    13. Black CL, Ocaña S, Riner D, Costales JA, Lascano MS, Davila S, Arcos-Teran L, Seed JR, Grijalva MJ. Household risk factors for Trypanosoma cruzi seropositivity in two geographic regions of Ecuador. J Parasitol. 2007 Feb; 93(1):12-6. PMID: 17436937.
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    14. Costales J, Rowland EC. Human chagasic serum contains antibodies capable of inhibiting Trypanosoma cruzi egress from tissue culture cells. J Parasitol. 2005 Aug; 91(4):950-3. PMID: 17089772.
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    15. Grijalva MJ, Palomeque-Rodríguez FS, Costales JA, Davila S, Arcos-Teran L. High household infestation rates by synanthropic vectors of Chagas disease in southern Ecuador. J Med Entomol. 2005 Jan; 42(1):68-74. PMID: 15691011.
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    16. Grijalva MJ, Escalante L, Paredes RA, Costales JA, Padilla A, Rowland EC, Aguilar HM, Racines J. Seroprevalence and risk factors for Trypanosoma cruzi infection in the Amazon region of Ecuador. Am J Trop Med Hyg. 2003 Oct; 69(4):380-5. PMID: 14640497.
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