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Dr Mitchell Allen Avery

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Avery MA, Choudhry SC, Dhingra OP, Gray BD, Kang MC, Kuo SC, Vedananda TR, White JD, Whittle AJ. Total synthesis of macrodiolide ionophores aplasmomycin A and boromycin via double ring contraction. Org Biomol Chem. 2014 Dec 07; 12(45):9116-32. PMID: 25096282.
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    2. Yang J, Liang Q, Wang M, Jeffries C, Smithson D, Tu Y, Boulos N, Jacob MR, Shelat AA, Wu Y, Ravu RR, Gilbertson R, Avery MA, Khan IA, Walker LA, Guy RK, Li XC. UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries. J Nat Prod. 2014 Apr 25; 77(4):902-9. PMID: 24617915.
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    3. Weldon DJ, Shah F, Chittiboyina AG, Sheri A, Chada RR, Gut J, Rosenthal PJ, Shivakumar D, Sherman W, Desai P, Jung JC, Avery MA. Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of a-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum. Bioorg Med Chem Lett. 2014 Mar 01; 24(5):1274-9. PMID: 24507921.
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    4. Porta EO, Carvalho PB, Avery MA, Tekwani BL, Labadie GR. Click chemistry decoration of amino sterols as promising strategy to developed new leishmanicidal drugs. Steroids. 2014 Jan; 79:28-36. PMID: 24200958.
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    5. Chittiboyina AG, Peddikotla P, Avery MA, Khan IA. Directed hydrogenation of acyclic homoallylic alcohols: enantioselective syntheses of (+)- and (-)-laurenditerpenol. J Org Chem. 2013 Sep 20; 78(18):9223-32. PMID: 23985032.
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    6. Pulcini S, Staines HM, Pittman JK, Slavic K, Doerig C, Halbert J, Tewari R, Shah F, Avery MA, Haynes RK, Krishna S. Expression in yeast links field polymorphisms in PfATP6 to in vitro artemisinin resistance and identifies new inhibitor classes. J Infect Dis. 2013 Aug 01; 208(3):468-78. PMID: 23599312.
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    7. Wu Y, Rodenburg DL, Ibrahim MA, McChesney JD, Avery MA. Stevioside methanol tetra-solvate. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 01; 69(Pt 3):o410-1. PMID: 23476589.
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    8. Helal MA, Avery MA. Combined receptor-based and ligand-based approach to delineate the mode of binding of guaianolide-endoperoxides to PfATP6. Bioorg Med Chem Lett. 2012 Sep 01; 22(17):5410-4. PMID: 22877631.
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    9. Shah F, Gut J, Legac J, Shivakumar D, Sherman W, Rosenthal PJ, Avery MA. Computer-aided drug design of falcipain inhibitors: virtual screening, structure-activity relationships, hydration site thermodynamics, and reactivity analysis. J Chem Inf Model. 2012 Mar 26; 52(3):696-710. PMID: 22332946.
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    10. Pabbisetty D, Illendula A, Muraleedharan KM, Chittiboyina AG, Williamson JS, Avery MA, Avery BA. Determination of antimalarial compound, ARB-89 (7ß-hydroxy-artemisinin carbamate) in rat serum by UPLC/MS/MS and its application in pharmacokinetics. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Mar 15; 889-890:123-9. PMID: 22365535.
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    11. Mukherjee P, Shah F, Desai P, Avery M. Inhibitors of SARS-3CLpro: virtual screening, biological evaluation, and molecular dynamics simulation studies. J Chem Inf Model. 2011 Jun 27; 51(6):1376-92. PMID: 21604711.
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    12. Shah F, Mukherjee P, Gut J, Legac J, Rosenthal PJ, Tekwani BL, Avery MA. Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library. J Chem Inf Model. 2011 Apr 25; 51(4):852-64. PMID: 21428453.
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    13. Helal MA, Chittiboyina AG, Avery MA. New insights into the binding mode of melanin concentrating hormone receptor-1 antagonists: homology modeling and explicit membrane molecular dynamics simulation study. J Chem Inf Model. 2011 Mar 28; 51(3):635-46. PMID: 21370821.
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    14. Ahmed R, Ali Z, Wu Y, Kulkarni S, Avery MA, Choudhary MI, Khan IA. Chemical characterization of a commercial Commiphora wightii resin sample and chemical profiling to assess for authenticity. Planta Med. 2011 Jun; 77(9):945-50. PMID: 21240842.
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    15. Sun L, Shah F, Helal MA, Wu Y, Pedduri Y, Chittiboyina AG, Gut J, Rosenthal PJ, Avery MA. Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents. J Med Chem. 2010 Nov 11; 53(21):7864-8. PMID: 20945914.
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    16. Na BK, Bae YA, Zo YG, Choe Y, Kim SH, Desai PV, Avery MA, Craik CS, Kim TS, Rosenthal PJ, Kong Y. Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4. PLoS Negl Trop Dis. 2010 Oct 12; 4(10):e849. PMID: 20967286.
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    17. Battu SK, Repka MA, Maddineni S, Chittiboyina AG, Avery MA, Majumdar S. Physicochemical characterization of berberine chloride: a perspective in the development of a solution dosage form for oral delivery. AAPS PharmSciTech. 2010 Sep; 11(3):1466-75. PMID: 20842541.
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    18. Mukherjee P, Desai P, Zhou YD, Avery M. Targeting the BH3 domain mediated protein-protein interaction of Bcl-xL through virtual screening. J Chem Inf Model. 2010 May 24; 50(5):906-23. PMID: 20392095.
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    19. Kulkarni SJ, Pedduri Y, Chittiboyina AG, Avery MA. Asymmetric total synthesis of the caspase-1 inhibitor (-)-berkeleyamide A. J Org Chem. 2010 May 07; 75(9):3113-6. PMID: 20356061.
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    20. Upadhye SB, Kulkarni SJ, Majumdar S, Avery MA, Gul W, ElSohly MA, Repka MA. Preparation and characterization of inclusion complexes of a hemisuccinate ester prodrug of delta9-tetrahydrocannabinol with modified beta-cyclodextrins. AAPS PharmSciTech. 2010 Jun; 11(2):509-17. PMID: 20333489.
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    21. Zeng F, Wang W, Wu Y, Dey M, Ye M, Avery MA, Khan IA, Guo DA. Two prenylated and C-methylated flavonoids from Tripterygium wilfordii. Planta Med. 2010 Oct; 76(14):1596-9. PMID: 20309799.
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    22. Shah F, Mukherjee P, Desai P, Avery M. Computational approaches for the discovery of cysteine protease inhibitors against malaria and SARS. Curr Comput Aided Drug Des. 2010 Mar; 6(1):1-23. PMID: 20370692.
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    23. Mizuno CS, Chittiboyina AG, Shah FH, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan VT, Carvalho PB, Avery MA. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. J Med Chem. 2010 Feb 11; 53(3):1076-85. PMID: 20073471.
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    24. Pradhan A, Tripathi AK, Desai PV, Mukherjee PK, Avery MA, Walker LA, Tekwani BL. Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket. Biochimie. 2009 Nov-Dec; 91(11-12):1509-17. PMID: 19772885.
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    25. Jain S, Abraham I, Carvalho P, Kuang YH, Shaala LA, Youssef DT, Avery MA, Chen ZS, El Sayed KA. Sipholane triterpenoids: chemistry, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling. J Nat Prod. 2009 Jul; 72(7):1291-8. PMID: 19534474.
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    26. Muraleedharan KM, Avery MA. Progress in the development of peroxide-based anti-parasitic agents. Drug Discov Today. 2009 Aug; 14(15-16):793-803. PMID: 19477287.
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    27. Shah F, Zhang SQ, Kandhari SP, Mukherjee P, Chittiboyina A, Avery MA, Avery BA. In vitro erythrocytic uptake studies of artemisinin and selected derivatives using LC-MS and 2D-QSAR analysis of uptake in parasitized erythrocytes. Bioorg Med Chem. 2009 Jul 15; 17(14):5325-31. PMID: 19497754.
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    28. Hammond N, Carvalho P, Wu Y, Avery MA. 3,3',5,5'-Tetra-nitro-biphen-yl. Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 18; 65(Pt 5):o1052-3. PMID: 21583870.
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    29. Zhang SQ, Vinnakota H, Jung JC, Carvalho P, Chittiboyina AG, Avery MA, Avery BA. Determination of a novel epothilone D analog (AV-EPO-106) in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry. Biomed Chromatogr. 2009 Mar; 23(3):302-7. PMID: 18800336.
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    30. Carvalho P, Kutrzeba LM, Zjawiony JK, Avery MA. (2S,4aR,6aR,7R,9S,10aS,10bR)-7-Carb-oxy-2-(3-fur-yl)-6a,10b-dimethyl-4,10-dioxoperhydro-benzo[f]isochromen-9-yl acetate. Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 06; 65(Pt 3):o471-2. PMID: 21582142.
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    31. Pradhan A, Mukherjee P, Tripathi AK, Avery MA, Walker LA, Tekwani BL. Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants. Mol Cell Biochem. 2009 May; 325(1-2):141-8. PMID: 19184366.
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    32. Gul W, Carvalho P, Galal A, Avery MA, El Sohly MA. 5-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethyl-perhydro-3,12-ep-oxy-1,2-dioxepino[4,3-i]isochromen-10-yl]oxymeth-yl}benzene-1,3-diol. Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 23; 65(Pt 2):o358-9. PMID: 21581957.
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    33. Fu X, Li XC, Smillie TJ, Carvalho P, Mabusela W, Syce J, Johnson Q, Folk W, Avery MA, Khan IA. Cycloartane glycosides from Sutherlandia frutescens. J Nat Prod. 2008 Oct; 71(10):1749-53. PMID: 18808182.
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    34. Li Z, Watkins EB, Liu H, Chittiboyina AG, Carvalho PB, Avery MA. 1,3-Diaxially substituted trans-decalins: potential nonsteroidal human progesterone receptor inhibitors. J Org Chem. 2008 Oct 03; 73(19):7764-7. PMID: 18771323.
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    35. Gul W, Carvalho P, Berberich DW, Avery MA, Elsohly MA. (6aR,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetra-hydro-6H-benzo[c]-chromen-1-yl 4-methyl-benzene-sulfonate. Acta Crystallogr Sect E Struct Rep Online. 2008 Aug 06; 64(Pt 9):o1686. PMID: 21201675.
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    36. Carvalho P, Bikbulatov R, Zjawiony JK, Avery MA. Unusual hemiacetal structure derived from Salvinorin A. Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 28; 64(Pt 7):o1370-1. PMID: 21202988.
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    37. Donia MS, Wang B, Dunbar DC, Desai PV, Patny A, Avery M, Hamann MT. Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle. J Nat Prod. 2008 Jun; 71(6):941-5. PMID: 18543965.
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    38. Rando DG, Avery MA, Tekwani BL, Khan SI, Ferreira EI. Antileishmanial activity screening of 5-nitro-2-heterocyclic benzylidene hydrazides. Bioorg Med Chem. 2008 Jul 15; 16(14):6724-31. PMID: 18571927.
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    39. Ali Z, Ferreira D, Carvalho P, Avery MA, Khan IA. Nigellidine-4-O-sulfite, the first sulfated indazole-type alkaloid from the seeds of Nigella sativa. J Nat Prod. 2008 Jun; 71(6):1111-2. PMID: 18471018.
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    40. Taranto AG, Carvalho P, Avery MA. QM/QM studies for Michael reaction in coronavirus main protease (3CL Pro). J Mol Graph Model. 2008 Oct; 27(3):275-85. PMID: 18567519.
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    41. Mukherjee P, Desai PV, Srivastava A, Tekwani BL, Avery MA. Probing the structures of leishmanial farnesyl pyrophosphate synthases: homology modeling and docking studies. J Chem Inf Model. 2008 May; 48(5):1026-40. PMID: 18419114.
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    42. Mukherjee P, Pradhan A, Shah F, Tekwani BL, Avery MA. Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. Bioorg Med Chem. 2008 May 01; 16(9):5254-65. PMID: 18362073.
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    43. Li L, Pabbisetty D, Zhu S, Avery MA, Avery BA. Urinary excretion study of coenzyme Q10 in rats by ultra-performance liquid chromatography-mass spectrometry. J Chromatogr Sci. 2008 Mar; 46(3):215-9. PMID: 18334087.
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    44. Srivastava A, Mukherjee P, Desai PV, Avery MA, Tekwani BL. Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target. Infect Disord Drug Targets. 2008 Mar; 8(1):16-30. PMID: 18473904.
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    45. Li L, Pabbisetty D, Carvalho P, Avery MA, Williamson JS, Avery BA. Ultra-performance liquid chromatography-tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 May 01; 867(1):131-7. PMID: 18353736.
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    46. Mizuno CS, Ma G, Khan S, Patny A, Avery MA, Rimando AM. Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARalpha. Bioorg Med Chem. 2008 Apr 01; 16(7):3800-8. PMID: 18272370.
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    47. Sayed KA, Khalil AA, Yousaf M, Labadie G, Kumar GM, Franzblau SG, Mayer AM, Avery MA, Hamann MT. Semisynthetic studies on the manzamine alkaloids. J Nat Prod. 2008 Mar; 71(3):300-8. PMID: 18198837.
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    48. Mukherjee P, Desai P, Ross L, White EL, Avery MA. Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits. Bioorg Med Chem. 2008 Apr 01; 16(7):4138-49. PMID: 18343121.
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    49. Carvalho PB, Liu B, Wu Y, Williamson JS, Avery MA. 7ß-Hydroxy-artemisinin. Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 09; 64(Pt 2):o395-6. PMID: 21201424.
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    50. Choi SR, Mukherjee P, Avery MA. The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008; 15(2):161-71. PMID: 18220771.
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    51. Mizuno CS, Chittiboyina AG, Kurtz TW, Pershadsingh HA, Avery MA. Type 2 diabetes and oral antihyperglycemic drugs. Curr Med Chem. 2008; 15(1):61-74. PMID: 18220763.
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    52. Chittiboyina AG, Kumar GM, Carvalho PB, Liu Y, Zhou YD, Nagle DG, Avery MA. Total synthesis and absolute configuration of laurenditerpenol: a hypoxia inducible factor-1 activation inhibitor. J Med Chem. 2007 Dec 13; 50(25):6299-302. PMID: 18004798.
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    53. Li L, Pabbisetty D, Carvalho P, Avery MA, Avery BA. Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration. J Pharm Biomed Anal. 2008 Jan 07; 46(1):137-42. PMID: 18054195.
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    54. Singh N, Avery MA, McCurdy CR. Toward Mycobacterium tuberculosis DXR inhibitor design: homology modeling and molecular dynamics simulations. J Comput Aided Mol Des. 2007 Sep; 21(9):511-22. PMID: 17874041.
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    55. Choi SR, Pradhan A, Hammond NL, Chittiboyina AG, Tekwani BL, Avery MA. Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors. J Med Chem. 2007 Aug 09; 50(16):3841-50. PMID: 17636950.
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    56. Kim TJ, Lim Y, Kim DW, Kwon JS, Son JH, Jin YR, Son DJ, Jung JC, Avery MA, Hong JT, Yun YP. Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins. Vascul Pharmacol. 2007 Oct; 47(4):229-37. PMID: 17706465.
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    57. Oh S, Moon HI, Son IH, Jung JC, Avery MA. Synthesis of sulfonamides and evaluation of their histone deacetylase (HDAC) activity. Molecules. 2007 May 24; 12(5):1125-35. PMID: 17873846.
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    58. Choi SR, Beeler AB, Pradhan A, Watkins EB, Rimoldi JM, Tekwani B, Avery MA. Generation of oxamic acid libraries: antimalarials and inhibitors of Plasmodium falciparum lactate dehydrogenase. J Comb Chem. 2007 Mar-Apr; 9(2):292-300. PMID: 17316052.
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    59. Lim Y, Kim TJ, Jin YR, Kim DW, Kwon JS, Son JH, Jung JC, Avery MA, Son DJ, Hong JT, Yun YP. Epothilone B inhibits neointimal formation after rat carotid injury through the regulation of cell cycle-related proteins. J Pharmacol Exp Ther. 2007 May; 321(2):648-55. PMID: 17289837.
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    60. Singh N, Chevé G, Avery MA, McCurdy CR. Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme. Curr Pharm Des. 2007; 13(11):1161-77. PMID: 17430177.
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    61. Patny A, Desai PV, Avery MA. Ligand-supported homology modeling of the human angiotensin II type 1 (AT(1)) receptor: insights into the molecular determinants of telmisartan binding. Proteins. 2006 Dec 01; 65(4):824-42. PMID: 17034041.
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    62. Menon RB, Kannoth MM, Tekwani BL, Gut J, Rosenthal PJ, Avery MA. A new library of C-16 modified artemisinin analogs and evaluation of their anti-parasitic activities. Comb Chem High Throughput Screen. 2006 Dec; 9(10):729-41. PMID: 17168678.
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    63. Chittiboyina AG, Venkatraman MS, Mizuno CS, Desai PV, Patny A, Benson SC, Ho CI, Kurtz TW, Pershadsingh HA, Avery MA. Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARgamma agonists. J Med Chem. 2006 Jul 13; 49(14):4072-84. PMID: 16821769.
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    64. Singh N, Chevé G, Avery MA, McCurdy CR. Comparative protein modeling of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme from Plasmodium falciparum: a potential target for antimalarial drug discovery. J Chem Inf Model. 2006 May-Jun; 46(3):1360-70. PMID: 16711755.
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    65. Mora FD, Jones DK, Desai PV, Patny A, Avery MA, Feller DR, Smillie T, Zhou YD, Nagle DG. Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells. J Nat Prod. 2006 Apr; 69(4):547-52. PMID: 16643023.
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    66. Desai PV, Patny A, Gut J, Rosenthal PJ, Tekwani B, Srivastava A, Avery M. Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory. J Med Chem. 2006 Mar 09; 49(5):1576-84. PMID: 16509575.
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    67. Patny A, Desai PV, Avery MA. Homology modeling of G-protein-coupled receptors and implications in drug design. Curr Med Chem. 2006; 13(14):1667-91. PMID: 16787212.
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    68. Parshikov IA, Miriyala B, Muraleedharan KM, Avery MA, Williamson JS. Microbial transformation of artemisinin to 5-hydroxyartemisinin by Eurotium amstelodami and Aspergillus niger. J Ind Microbiol Biotechnol. 2006 May; 33(5):349-52. PMID: 16389544.
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    69. Bhagavathula N, Nerusu KC, Reddy M, Ellis CN, Chittiboyina A, Avery M, Pershadsingh HA, Kurtz TW, Varani J. BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. J Pharmacol Exp Ther. 2005 Dec; 315(3):996-1004. PMID: 16109743.
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    70. Burk O, Arnold KA, Nussler AK, Schaeffeler E, Efimova E, Avery BA, Avery MA, Fromm MF, Eichelbaum M. Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor. Mol Pharmacol. 2005 Jun; 67(6):1954-65. PMID: 15761118.
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    71. Watkins EB, Chittiboyina AG, Jung JC, Avery MA. The epothilones and related analogues-a review of their syntheses and anti-cancer activities. Curr Pharm Des. 2005; 11(13):1615-53. PMID: 15892666.
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    72. Jung JC, Kache R, Vines KK, Zheng YS, Bijoy P, Valluri M, Avery MA. Total syntheses of epothilones B and d. J Org Chem. 2004 Dec 24; 69(26):9269-84. PMID: 15609966.
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    73. Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M. Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. J Med Chem. 2004 Dec 16; 47(26):6609-15. PMID: 15588096.
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    74. Sawant SS, Sylvester PW, Avery MA, Desai P, Youssef DT, El Sayed KA. Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine. J Nat Prod. 2004 Dec; 67(12):2017-23. PMID: 15620244.
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    75. McLuskey K, Gibellini F, Carvalho P, Avery MA, Hunter WN. Inhibition of Leishmania major pteridine reductase by 2,4,6-triaminoquinazoline: structure of the NADPH ternary complex. Acta Crystallogr D Biol Crystallogr. 2004 Oct; 60(Pt 10):1780-5. PMID: 15388924.
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    76. Tripathi AK, Desai PV, Pradhan A, Khan SI, Avery MA, Walker LA, Tekwani BL. An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme. Eur J Biochem. 2004 Sep; 271(17):3488-502. PMID: 15317584.
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    77. Parshikov IA, Muraleedharan KM, Miriyala B, Avery MA, Williamson JS. Hydroxylation of 10-deoxoartemisinin by Cunninghamella elegans. J Nat Prod. 2004 Sep; 67(9):1595-7. PMID: 15387669.
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    78. Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz TW, Benson SC. Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Arch Dermatol Res. 2004 Aug; 296(3):97-104. PMID: 15221328.
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    79. Desai PV, Avery MA. Structural characterization of vivapain-2 and vivapain-3, cysteine proteases from Plasmodium vivax: comparative protein modeling and docking studies. J Biomol Struct Dyn. 2004 Jun; 21(6):781-90. PMID: 15107000.
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    80. Parshikov IA, Miriyala B, Avery MA, Williamson JS. Hydroxylation of 10-deoxoartemisinin to 15-hydroxy-10-deoxoartemisinin by Aspergillus niger. Biotechnol Lett. 2004 Apr; 26(7):607-10. PMID: 15168863.
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    81. Benson SC, Pershadsingh HA, Ho CI, Chittiboyina A, Desai P, Pravenec M, Qi N, Wang J, Avery MA, Kurtz TW. Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension. 2004 May; 43(5):993-1002. PMID: 15007034.
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    82. Labadie GR, Choi SR, Avery MA. Diamine derivatives with antiparasitic activities. Bioorg Med Chem Lett. 2004 Feb 09; 14(3):615-9. PMID: 14741254.
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    83. Parshikov IA, Muraleedharan KM, Avery MA, Williamson JS. Transformation of artemisinin by Cunninghamella elegans. Appl Microbiol Biotechnol. 2004 Jun; 64(6):782-6. PMID: 14735322.
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    84. Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, Ho CI, Benson SC, Pershadsingh HA, Kurtz TW, Varani J. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. J Invest Dermatol. 2004 Jan; 122(1):130-9. PMID: 14962101.
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    85. Peng J, Avery MA, Hamann MT. Cyanthiwigin AC and AD, two novel diterpene skeletons from the Jamaican sponge Myrmekioderma styx. Org Lett. 2003 Nov 27; 5(24):4575-8. PMID: 14627387.
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    86. Peng J, Hu JF, Kazi AB, Li Z, Avery M, Peraud O, Hill RT, Franzblau SG, Zhang F, Schinazi RF, Wirtz SS, Tharnish P, Kelly M, Wahyuono S, Hamann MT. Manadomanzamines A and B: a novel alkaloid ring system with potent activity against mycobacteria and HIV-1. J Am Chem Soc. 2003 Nov 05; 125(44):13382-6. PMID: 14583033.
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    87. Avery MA, Muraleedharan KM, Desai PV, Bandyopadhyaya AK, Furtado MM, Tekwani BL. Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria. J Med Chem. 2003 Sep 25; 46(20):4244-58. PMID: 13678403.
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    88. Batra S, Sabnis YA, Rosenthal PJ, Avery MA. Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines. Bioorg Med Chem. 2003 May 15; 11(10):2293-9. PMID: 12713840.
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    89. Illapakurthy AC, Sabnis YA, Avery BA, Avery MA, Wyandt CM. Interaction of artemisinin and its related compounds with hydroxypropyl-beta-cyclodextrin in solution state: experimental and molecular-modeling studies. J Pharm Sci. 2003 Mar; 92(3):649-55. PMID: 12587126.
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    90. Sabnis YA, Desai PV, Rosenthal PJ, Avery MA. Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies. Protein Sci. 2003 Mar; 12(3):501-9. PMID: 12592020.
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    91. Minenoa T, Avery MA. Giardiasis: recent progress in chemotherapy and drug development. Curr Pharm Des. 2003; 9(11):841-55. PMID: 12678869.
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    92. El Sayed KA, Yousaf M, Hamann MT, Avery MA, Kelly M, Wipf P. Microbial and chemical transformation studies of the bioactive marine sesquiterpenes (S)-(+)-curcuphenol and -curcudiol isolated from a deep reef collection of the Jamaican sponge Didiscus oxeata. J Nat Prod. 2002 Nov; 65(11):1547-53. PMID: 12444675.
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    93. Lima PC, Avery MA, Tekwani BL, de Alves HM, Barreiro EJ, Fraga CA. Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues. Farmaco. 2002 Oct; 57(10):825-32. PMID: 12420878.
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    94. Avery MA, Alvim-Gaston M, Vroman JA, Wu B, Ager A, Peters W, Robinson BL, Charman W. Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates. J Med Chem. 2002 Sep 12; 45(19):4321-35. PMID: 12213073.
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    95. Mineno T, Stanford KM, Walker LA, Avery MA. Solution-phase parallel synthesis of an isoflavone library for the discovery of novel antigiardial agents. Comb Chem High Throughput Screen. 2002 Sep; 5(6):481-7. PMID: 12470277.
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    96. Jaradat MS, Noonan DJ, Wu B, Avery MA, Feller DR, Jardat MS. Pseudolaric acid analogs as a new class of peroxisome proliferator-activated receptor agonists. Planta Med. 2002 Aug; 68(8):667-71. PMID: 12221584.
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    97. Sabnis Y, Rosenthal PJ, Desai P, Avery MA. Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors. J Biomol Struct Dyn. 2002 Apr; 19(5):765-74. PMID: 11922834.
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    98. Avery MA, Alvim-Gaston M, Rodrigues CR, Barreiro EJ, Cohen FE, Sabnis YA, Woolfrey JR. Structure-activity relationships of the antimalarial agent artemisinin. 6. The development of predictive in vitro potency models using CoMFA and HQSAR methodologies. J Med Chem. 2002 Jan 17; 45(2):292-303. PMID: 11784134.
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    99. Vyas N, Avery BA, Avery MA, Wyandt CM. Carrier-mediated partitioning of artemisinin into Plasmodium falciparum-infected erythrocytes. Antimicrob Agents Chemother. 2002 Jan; 46(1):105-9. PMID: 11751119.
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    100. Valluri M, Hindupur RM, Bijoy P, Labadie G, Jung JC, Avery MA. Total synthesis of epothilone B. Org Lett. 2001 Nov 15; 3(23):3607-9. PMID: 11700093.
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    101. Khan IA, Avery MA, Burandt CL, Goins DK, Mikell JR, Nash TE, Azadegan A, Walker LA. Antigiardial activity of isoflavones from Dalbergia frutescens bark. J Nat Prod. 2000 Oct; 63(10):1414-6. PMID: 11076565.
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    102. Avery BA, Venkatesh KK, Avery MA. Rapid determination of artemisinin and related analogues using high-performance liquid chromatography and an evaporative light scattering detector. J Chromatogr B Biomed Sci Appl. 1999 Jun 25; 730(1):71-80. PMID: 10437674.
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    103. Vroman JA, Alvim-Gaston M, Avery MA. Current progress in the chemistry, medicinal chemistry and drug design of artemisinin based antimalarials. Curr Pharm Des. 1999 Feb; 5(2):101-38. PMID: 10066886.
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    104. Johnson T, Khan IA, Avery MA, Grant J, Meshnick SR. Quantitative structure-activity relationship studies of a series of sulfa drugs as inhibitors of Pneumocystis carinii dihydropteroate synthetase. Antimicrob Agents Chemother. 1998 Jun; 42(6):1454-8. PMID: 9624493.
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    105. Woolfrey JR, Avery MA, Doweyko AM. Comparison of 3D quantitative structure-activity relationship methods: analysis of the in vitro antimalarial activity of 154 artemisinin analogues by hypothetical active-site lattice and comparative molecular field analysis. J Comput Aided Mol Des. 1998 Mar; 12(2):165-81. PMID: 9690175.
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    106. Avery MA, Mehrotra S, Johnson TL, Bonk JD, Vroman JA, Miller R. Structure-activity relationships of the antimalarial agent artemisinin. 5. Analogs of 10-deoxoartemisinin substituted at C-3 and C-9. J Med Chem. 1996 Oct 11; 39(21):4149-55. PMID: 8863791.
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    107. Avery MA, Mehrotra S, Bonk JD, Vroman JA, Goins DK, Miller R. Structure-activity relationships of the antimalarial agent artemisinin. 4. Effect of substitution at C-3. J Med Chem. 1996 Jul 19; 39(15):2900-6. PMID: 8709124.
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    108. Avery MA, Fan P, Karle JM, Bonk JD, Miller R, Goins DK. Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures. J Med Chem. 1996 Apr 26; 39(9):1885-97. PMID: 8627612.
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    109. Meshnick SR, Jefford CW, Posner GH, Avery MA, Peters W. Second-generation antimalarial endoperoxides. Parasitol Today. 1996 Feb; 12(2):79-82. PMID: 15275260.
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    110. Avery MA, Bonk JD, Chong WK, Mehrotra S, Miller R, Milhous W, Goins DK, Venkatesan S, Wyandt C, Khan I, et al. Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins. J Med Chem. 1995 Dec 22; 38(26):5038-44. PMID: 8544180.
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    111. Kamchonwongpaisan S, Chandra-ngam G, Avery MA, Yuthavong Y. Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes. J Clin Invest. 1994 Feb; 93(2):467-73. PMID: 8113385.
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    112. Avery MA, Gao F, Chong WK, Mehrotra S, Milhous WK. Structure-activity relationships of the antimalarial agent artemisinin. 1. Synthesis and comparative molecular field analysis of C-9 analogs of artemisinin and 10-deoxoartemisinin. J Med Chem. 1993 Dec 24; 36(26):4264-75. PMID: 8277509.
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    113. Avery MA, Detre G, Yasuda D, Chao WR, Tanabe M, Crowe D, Peters R, Chong WK. Synthesis and antiinflammatory activity of novel 12 beta-substituted analogues of betamethasone. J Med Chem. 1990 Jul; 33(7):1852-8. PMID: 2362263.
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    114. Avery MA, Tanabe M, Crowe DF, Detre G, Peters RH, Chong WK. Synthesis and testing of 17a beta-hydroxy-7 alpha-methyl-D-homoestra-4,16-dien-3-one: a highly potent orally active androgen. Steroids. 1990 Feb; 55(2):59-64. PMID: 2326828.
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    115. Peters RH, Crowe DF, Avery MA, Chong WK, Tanabe M. 11 beta-nitrate estrane analogues: potent estrogens. J Med Chem. 1989 Oct; 32(10):2306-10. PMID: 2795603.
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    116. Peters RH, Crowe DF, Avery MA, Chong WK, Tanabe M. 17-Desoxy estrogen analogues. J Med Chem. 1989 Jul; 32(7):1642-52. PMID: 2738897.
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    117. Peters RH, Crowe DF, Avery MA, Chong WK, Tanabe M. Analogues of [(triethylsilyl)ethynyl]estradiol as potential antifertility agents. J Med Chem. 1988 Mar; 31(3):572-6. PMID: 3346872.
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    118. Peters RH, Crowe DF, Tanabe M, Avery MA, Chong WK. Steroidal silicon side-chain analogues as potential antifertility agents. J Med Chem. 1987 Apr; 30(4):646-52. PMID: 3560158.
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    119. Reitz AB, Avery MA, Rosenkranz RP, Verlander MS, Melmon KL, Hoffman BB, Akita Y, Castagnoli N, Goodman M. Conjugates of catecholamines. 6. Synthesis and beta-adrenergic activity of N-(hydroxyalkyl)catecholamine derivatives. J Med Chem. 1985 May; 28(5):642-7. PMID: 2859373.
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