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Professor Andrew Nunn

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Nunn A, Anywaine Z, Seeley J, Munderi P, Levin J, Kasirye R, Kamali A, Abaasa A, Grosskurth H. Exit interviews administered to patients participating in the COSTOP placebo controlled randomised trial in Uganda. Contemp Clin Trials Commun. 2016 Aug 15; 3:142-146. PMID: 27536738.
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    2. Kasirye R, Grosskurth H, Munderi P, Levin J, Anywaine Z, Nunn A, Kamali A, Baisley K. Longitudinal effect of CD4 by cotrimoxazole use on malaria incidence among HIV-infected Ugandan adults on antiretroviral therapy: a randomized controlled study. Malar J. 2016 Jul 15; 15:361. PMID: 27417903; PMCID: PMC4946223.
    3. Furin J, Alirol E, Allen E, Fielding K, Merle C, Abubakar I, Andersen J, Davies G, Dheda K, Diacon A, Dooley KE, Dravnice G, Eisenach K, Everitt D, Ferstenberg D, Goolam-Mahomed A, Grobusch MP, Gupta R, Harausz E, Harrington M, Horsburgh CR, Lienhardt C, McNeeley D, Mitnick CD, Nachman S, Nahid P, Nunn AJ, Phillips P, Rodriguez C, Shah S, Wells C, Thomas-Nyang'wa B, du Cros P. Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults. Int J Tuberc Lung Dis. 2016 Mar; 20(3):290-4. PMID: 27046707; PMCID: PMC4843774.
    4. Phillips PP, Mendel CM, Burger DA, Crook AM, Nunn AJ, Dawson R, Diacon AH, Gillespie SH. Erratum to: Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials. BMC Med. 2016 Feb 23; 14:36. PMID: 26905218; PMCID: PMC4765164.
    5. Kasirye RP, Baisley K, Munderi P, Levin J, Anywaine Z, Nunn A, Kamali A, Grosskurth H. Incidence of malaria by cotrimoxazole use in HIV-infected Ugandan adults on antiretroviral therapy: a randomised, placebo-controlled study. AIDS. 2016 Feb 20; 30(4):635-44. PMID: 26558729; PMCID: PMC4732005.
    6. Phillips PP, Mendel CM, Burger DA, Crook AM, Crook A, Nunn AJ, Dawson R, Diacon AH, Gillespie SH. Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials. BMC Med. 2016 Feb 04; 14:19. PMID: 26847437; PMCID: PMC4743210.
    7. Nunn AJ, Phillips PP, Abubakar I. Reducing relapse in tuberculosis treatment. Int J Tuberc Lung Dis. 2015 Oct; 19(10):1263-4. PMID: 26459549.
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    8. Anywaine Z, Abaasa A, Levin J, Kasirye R, Kamali A, Grosskurth H, Munderi P, Nunn A. Safety of discontinuing cotrimoxazole prophylaxis among HIV infected adults on anti-retroviral therapy in Uganda (COSTOP trial): Design. Contemp Clin Trials. 2015 Jul; 43:100-4. PMID: 26009024; PMCID: PMC4542218.
    9. Jindani A, Harrison TS, Nunn AJ, Phillips PP, Churchyard GJ, Charalambous S, Hatherill M, Geldenhuys H, McIlleron HM, Zvada SP, Mungofa S, Shah NA, Zizhou S, Magweta L, Shepherd J, Nyirenda S, van Dijk JH, Clouting HE, Coleman D, Bateson AL, McHugh TD, Butcher PD, Mitchison DA. High-dose rifapentine with moxifloxacin for pulmonary tuberculosis. N Engl J Med. 2014 Oct 23; 371(17):1599-608. PMID: 25337749; PMCID: PMC4233406.
    10. Nunn AJ, Cook SV, Burgos M, Rigouts L, Yorke-Edwards V, Anyo G, Kim SJ, Enarson DA, Jindani A, Lienhardt C. Results at 30 months of a randomised trial of FDCs and separate drugs for the treatment of tuberculosis. Int J Tuberc Lung Dis. 2014 Oct; 18(10):1252-4. PMID: 25216842.
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    11. Gillespie SH, Crook AM, McHugh TD, Mendel CM, Meredith SK, Murray SR, Pappas F, Phillips PP, Nunn AJ. Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis. N Engl J Med. 2014 Oct 23; 371(17):1577-87. PMID: 25196020; PMCID: PMC4277680.
    12. Crook AM, Ford D, Gafos M, Hayes R, Kamali A, Kapiga S, Nunn A, Chisembele M, Ramjee G, Rees H, McCormack S. Injectable and oral contraceptives and risk of HIV acquisition in women: an analysis of data from the MDP301 trial. Hum Reprod. 2014 Aug; 29(8):1810-7. PMID: 24838704; PMCID: PMC4093991.
    13. Zumla AI, Gillespie SH, Hoelscher M, Philips PP, Cole ST, Abubakar I, McHugh TD, Schito M, Maeurer M, Nunn AJ. New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects. Lancet Infect Dis. 2014 Apr; 14(4):327-40. PMID: 24670627.
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    14. Phillips PP, Nunn AJ, Paton NI. Is a 4-month regimen adequate to cure patients with non-cavitary tuberculosis and negative cultures at 2 months? Int J Tuberc Lung Dis. 2013 Jun; 17(6):807-9. PMID: 23676166.
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    15. Phillips PP, Fielding K, Nunn AJ. An evaluation of culture results during treatment for tuberculosis as surrogate endpoints for treatment failure and relapse. PLoS One. 2013; 8(5):e63840. PMID: 23667677; PMCID: PMC3648512.
    16. Abaasa A, Crook A, Gafos M, Anywaine Z, Levin J, Wandiembe S, Nanoo A, Nunn A, McCormack S, Hayes R, Kamali A. Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda. Trials. 2013 Feb 01; 14:33. PMID: 23374729; PMCID: PMC3564905.
    17. Nunn A. Challenging trials. Int J Tuberc Lung Dis. 2012 Dec; 16(12):1563. PMID: 23131250.
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    18. Phillips PP, Gillespie SH, Boeree M, Heinrich N, Aarnoutse R, McHugh T, Pletschette M, Lienhardt C, Hafner R, Mgone C, Zumla A, Nunn AJ, Hoelscher M. Innovative trial designs are practical solutions for improving the treatment of tuberculosis. J Infect Dis. 2012 May 15; 205 Suppl 2:S250-7. PMID: 22448027.
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    19. Zumla A, Hafner R, Lienhardt C, Hoelscher M, Nunn A. Advancing the development of tuberculosis therapy. Nat Rev Drug Discov. 2012 03 01; 11(3):171-2. PMID: 22378254.
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    20. Nunn AJ, Jindani A, Enarson DA. Results at 30 months of a randomised trial of two 8-month regimens for the treatment of tuberculosis. Int J Tuberc Lung Dis. 2011 Jun; 15(6):741-5. PMID: 21575292.
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    21. Lienhardt C, Cook SV, Burgos M, Yorke-Edwards V, Rigouts L, Anyo G, Kim SJ, Jindani A, Enarson DA, Nunn AJ. Efficacy and safety of a 4-drug fixed-dose combination regimen compared with separate drugs for treatment of pulmonary tuberculosis: the Study C randomized controlled trial. JAMA. 2011 Apr 13; 305(14):1415-23. PMID: 21486974.
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    22. Bratton DJ, Nunn AJ. Alternative approaches to tuberculosis treatment evaluation: the role of pragmatic trials. Int J Tuberc Lung Dis. 2011 Apr; 15(4):440-6. PMID: 21396200.
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    23. Nunn AJ, Mwaba PB, Chintu C, Crook AM, Darbyshire JH, Ahmed Y, Zumla AI. Randomised, placebo-controlled trial to evaluate co-trimoxazole to reduce mortality and morbidity in HIV-infected post-natal women in Zambia (TOPAZ). Trop Med Int Health. 2011 Apr; 16(4):518-26. PMID: 21281407.
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    24. Perrin FM, Woodward N, Phillips PP, McHugh TD, Nunn AJ, Lipman MC, Gillespie SH. Radiological cavitation, sputum mycobacterial load and treatment response in pulmonary tuberculosis. Int J Tuberc Lung Dis. 2010 Dec; 14(12):1596-602. PMID: 21144246.
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    25. Nunn A. What is the role of clinical trials for the treatment of tuberculosis and what are the alternatives? Int J Tuberc Lung Dis. 2010 Apr; 14(4):380-1. PMID: 20202292.
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    26. Nunn AJ, Phillips PP, Mitchison DA. Timing of relapse in short-course chemotherapy trials for tuberculosis. Int J Tuberc Lung Dis. 2010 Feb; 14(2):241-2. PMID: 20074418.
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    27. Nunn AJ, Phillips PP, Gillespie SH. Design issues in pivotal drug trials for drug sensitive tuberculosis (TB). Tuberculosis (Edinb). 2008 Aug; 88 Suppl 1:S85-92. PMID: 18762156.
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    28. Nunn AJ, Mwaba P, Chintu C, Mwinga A, Darbyshire JH, Zumla A. Role of co-trimoxazole prophylaxis in reducing mortality in HIV infected adults being treated for tuberculosis: randomised clinical trial. BMJ. 2008 Jul 10; 337:a257. PMID: 18617486; PMCID: PMC2656923.
    29. Walker AS, Ford D, Mulenga V, Thomason MJ, Nunn A, Chintu C, Gibb DM, Bangsberg DR. Adherence to both cotrimoxazole and placebo is associated with improved survival among HIV-infected Zambian children. AIDS Behav. 2009 Feb; 13(1):33-41. PMID: 18401699.
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    30. Nunn AJ, Meredith SK, Spigelman MK, Ginsberg AM, Gillespie SH. The ethics of non-inferiority trials. Lancet. 2008 Mar 15; 371(9616):895; author reply 896-7. PMID: 18342678.
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    31. Ciglenecki I, Glynn JR, Mwinga A, Ngwira B, Zumla A, Fine PE, Nunn A. Population differences in death rates in HIV-positive patients with tuberculosis. Int J Tuberc Lung Dis. 2007 Oct; 11(10):1121-8. PMID: 17945070.
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    32. Thomas KS, Cox NH, Savelyich BS, Shipley D, Meredith S, Nunn A, Reynolds N, Williams HC. Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg. Trials. 2007 Jan 26; 8:3. PMID: 17257411; PMCID: PMC1797057.
    33. Mulenga V, Ford D, Walker AS, Mwenya D, Mwansa J, Sinyinza F, Lishimpi K, Nunn A, Gillespie S, Zumla A, Chintu C, Gibb DM. Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children. AIDS. 2007 Jan 02; 21(1):77-84. PMID: 17148971.
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    34. Walker AS, Mulenga V, Sinyinza F, Lishimpi K, Nunn A, Chintu C, Gibb DM. Determinants of survival without antiretroviral therapy after infancy in HIV-1-infected Zambian children in the CHAP Trial. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):637-45. PMID: 16868501.
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    35. Bakobaki JM, Lacey CJ, Bukenya MI, Nunn AJ, McCormack S, Byaruhanga RN, Okong P, Namukwaya SW, Grosskurth H, Whitworth JA. A randomized controlled safety and acceptability trial of dextrin sulphate vaginal microbicide gel in sexually active women in Uganda. AIDS. 2005 Dec 02; 19(18):2149-56. PMID: 16284465.
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    36. Johnson JL, Nunn AJ, Fourie PB, Ormerod LP, Mugerwa RD, Mwinga A, Chintu C, Ngwira B, Onyebujoh P, Zumla A. Effect of Mycobacterium vaccae (SRL172) immunotherapy on radiographic healing in tuberculosis. Int J Tuberc Lung Dis. 2004 Nov; 8(11):1348-54. PMID: 15581204.
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    37. Chintu C, Bhat GJ, Walker AS, Mulenga V, Sinyinza F, Lishimpi K, Farrelly L, Kaganson N, Zumla A, Gillespie SH, Nunn AJ, Gibb DM. Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): a double-blind randomised placebo-controlled trial. Lancet. 2004 Nov 20-26; 364(9448):1865-71. PMID: 15555666.
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    38. Jindani A, Nunn AJ, Enarson DA. Two 8-month regimens of chemotherapy for treatment of newly diagnosed pulmonary tuberculosis: international multicentre randomised trial. Lancet. 2004 Oct 2-8; 364(9441):1244-51. PMID: 15464185.
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    39. Mwaba P, Cassol S, Nunn A, Pilon R, Chintu C, Janes M, Zumla A. Whole blood versus plasma spots for measurement of HIV-1 viral load in HIV-infected African patients. Lancet. 2003 Dec 20; 362(9401):2067-8. PMID: 14697808.
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    40. Mwaba P, Cassol S, Pilon R, Chintu C, Janes M, Nunn A, Zumla A. Use of dried whole blood spots to measure CD4+ lymphocyte counts in HIV-1-infected patients. Lancet. 2003 Nov 01; 362(9394):1459-60. PMID: 14602443.
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    41. Balasegaram S, Watson JM, Rose AM, Charlett A, Nunn AJ, Rushdy A, Leese J, Ormerod LP. A decade of change: tuberculosis in England and Wales 1988-98. Arch Dis Child. 2003 Sep; 88(9):772-7. PMID: 12937094; PMCID: PMC1719643.
    42. Kamali A, Kinsman J, Nalweyiso N, Mitchell K, Kanyesigye E, Kengeya-Kayondo JF, Carpenter LM, Nunn A, Whitworth JA. A community randomized controlled trial to investigate impact of improved STD management and behavioural interventions on HIV incidence in rural Masaka, Uganda: trial design, methods and baseline findings. Trop Med Int Health. 2002 Dec; 7(12):1053-63. PMID: 12460397.
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    43. Mwinga A, Nunn A, Ngwira B, Chintu C, Warndorff D, Fine P, Darbyshire J, Zumla A. Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial. Lancet. 2002 Oct 05; 360(9339):1050-5. PMID: 12383985.
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    44. Chintu C, Mudenda V, Lucas S, Nunn A, Lishimpi K, Maswahu D, Kasolo F, Mwaba P, Bhat G, Terunuma H, Zumla A. Lung diseases at necropsy in African children dying from respiratory illnesses: a descriptive necropsy study. Lancet. 2002 Sep 28; 360(9338):985-90. PMID: 12383668.
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    45. Lishimpi K, Kasolo F, Chintu C, Mwaba P, Mudenda V, Maswahu D, Terunuma H, Fletcher H, Nunn A, Lucas S, Zumla A. Identification of Pneumocystis carinii DNA in oropharyngeal mouth washes from AIDS children dying of respiratory illnesses. AIDS. 2002 Apr 12; 16(6):932-4. PMID: 11919499.
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    46. Kasolo F, Lishimpi K, Chintu C, Mwaba P, Mudenda V, Maswahu D, Terunuma H, Fletcher H, Nunn A, Lucas S, Zumla A. Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. J Pediatr. 2002 Mar; 140(3):367-9. PMID: 11953737.
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    47. Lishimpi K, Chintu C, Lucas S, Mudenda V, Kaluwaji J, Story A, Maswahu D, Bhat G, Nunn AJ, Zumla A. Necropsies in African children: consent dilemmas for parents and guardians. Arch Dis Child. 2001 Jun; 84(6):463-7. PMID: 11369557; PMCID: PMC1718810.
    48. Rose AM, Watson JM, Graham C, Nunn AJ, Drobniewski F, Ormerod LP, Darbyshire JH, Leese J. Tuberculosis at the end of the 20th century in England and Wales: results of a national survey in 1998. Thorax. 2001 Mar; 56(3):173-9. PMID: 11182007; PMCID: PMC1758771.
    49. Aaby P, Babiker A, Darbyshire J, Nunn A, Barreto S, Alonso P, Badaro R, Barros F, Victoria C, Binka F, Biryahwaho B, Byabamazima C, Sempala S, Tugume B, Kalebu P, Kengeya-Kayondo J, Whitworth J, Paxton L, Convit J, Corrah T, McAdam K, Datta M, Dowlati Y, Fine P, Tanner M, et al. Ethics of HIV trials. Lancet. 1997 Nov 22; 350(9090):1546. PMID: 9388413.
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    50. Nunn AJ, Mulder DW, Kamali A, Ruberantwari A, Kengeya-Kayondo JF, Whitworth J. Mortality associated with HIV-1 infection over five years in a rural Ugandan population: cohort study. BMJ. 1997 Sep 27; 315(7111):767-71. PMID: 9345167; PMCID: PMC2127535.
    51. Kamali A, Seeley JA, Nunn AJ, Kengeya-Kayondo JF, Ruberantwari A, Mulder DW. The orphan problem: experience of a sub-Saharan Africa rural population in the AIDS epidemic. AIDS Care. 1996 Oct; 8(5):509-15. PMID: 8893902.
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    52. Kengeya-Kayondo JF, Kamali A, Nunn AJ, Ruberantwari A, Wagner HU, Mulder DW. Incidence of HIV-1 infection in adults and socio-demographic characteristics of seroconverters in a rural population in Uganda: 1990-1994. Int J Epidemiol. 1996 Oct; 25(5):1077-82. PMID: 8921497.
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    53. Nunn AJ, Mulder DW, Kamali A, Kengeya-Kayondo JF, Whitworth JA. HIV-1 incidence in sub-Saharan Africa. Lancet. 1996 Sep 21; 348(9030):833-4. PMID: 8814018.
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    54. Ormerod LP, Nunn AJ, Byfield SP, Darbyshire JH. Patterns of tuberculosis in Indian and Pakistani/Bangladeshi patients: effects of age, date of first entry and ethnic group. Respir Med. 1991 Jul; 85(4):275-80. PMID: 1947363.
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    55. Berkani M, Chaulet P, Darbyshire JH, Nunn A, Fox W. [Results of a therapeutic trial comparing a 6-month regimen to a 12-month regimen in the treatment of pulmonary tuberculosis in the Algerian Sahara. Final report: results 3 years after the onset of treatment]. Rev Mal Respir. 1986; 3(2):73-85. PMID: 3726263.
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    56. Humphries MJ, Byfield SP, Darbyshire JH, Davies PD, Nunn AJ, Citron KM, Fox W. Deaths occurring in newly notified patients with pulmonary tuberculosis in England and Wales. Br J Dis Chest. 1984 Apr; 78(2):149-58. PMID: 6722018.
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    57. Heffernan JF, Nunn AJ, Peto J, Fox W. Pulmonary tuberculosis in Scotland: a national sample survey and follow-up (1968-70). 1. The characteristics of the cases notified in 1968. Tubercle. 1975 Dec; 56(4):253-67. PMID: 820025.
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    58. Miller AB, Nunn AJ, Robinson DK, Fox W, Somasundaram PR, Tall R. A second international cooperative investigation into tioacetazone side effects. Bull World Health Organ. 1972; 47(2):211-27. PMID: 4118761; PMCID: PMC2480900.
    59. Kent PW, Fox W, Miller AB, Nunn AJ, Tall R, Mitchison DA. The therapy of pulmonary tuberculosis in Kenya: a comparison of the results achieved in controlled clinical trials with those achieved by the routine treatment services. Tubercle. 1970 Mar; 51(1):24-38. PMID: 4099826.
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