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Dr Karen Patricia Day

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rorick MM, Rask TS, Baskerville EB, Day KP, Pascual M. Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population. BMC Microbiol. 2013 Nov 06; 13:244. PMID: 24192078; PMCID: PMC3827005.
    2. Rougeron V, Woods CM, Tiedje KE, Bodeau-Livinec F, Migot-Nabias F, Deloron P, Luty AJ, Fowkes FJ, Day KP. Epistatic Interactions between apolipoprotein E and hemoglobin S Genes in regulation of malaria parasitemia. PLoS One. 2013; 8(10):e76924. PMID: 24116184; PMCID: PMC3792892.
    3. Zilversmit MM, Chase EK, Chen DS, Awadalla P, Day KP, McVean G. Hypervariable antigen genes in malaria have ancient roots. BMC Evol Biol. 2013 May 31; 13:110. PMID: 23725540; PMCID: PMC3680017.
    4. Artzy-Randrup Y, Rorick MM, Day K, Chen D, Dobson AP, Pascual M. Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum. Elife. 2012 Dec 18; 1:e00093. PMID: 23251784; PMCID: PMC3524794.
    5. Imrie HJ, Fowkes FJ, Migot-Nabias F, Luty AJ, Deloron P, Hajduk SL, Day KP. Individual variation in levels of haptoglobin-related protein in children from Gabon. PLoS One. 2012; 7(11):e49816. PMID: 23185445; PMCID: PMC3502254.
    6. Bodeau-Livinec F, Briand V, Berger J, Xiong X, Massougbodji A, Day KP, Cot M. Maternal anemia in Benin: prevalence, risk factors, and association with low birth weight. Am J Trop Med Hyg. 2011 Sep; 85(3):414-20. PMID: 21896797; PMCID: PMC3163859.
    7. Day KP, Fowkes FJ. Microbiology. Quantifying malaria dynamics within the host. Science. 2011 Aug 19; 333(6045):943-4. PMID: 21852478.
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    8. Barry AE, Trieu A, Fowkes FJ, Pablo J, Kalantari-Dehaghi M, Jasinskas A, Tan X, Kayala MA, Tavul L, Siba PM, Day KP, Baldi P, Felgner PL, Doolan DL. The stability and complexity of antibody responses to the major surface antigen of Plasmodium falciparum are associated with age in a malaria endemic area. Mol Cell Proteomics. 2011 Nov; 10(11):M111.008326. PMID: 21825279; PMCID: PMC3226400.
    9. Chen DS, Barry AE, Leliwa-Sytek A, Smith TA, Peterson I, Brown SM, Migot-Nabias F, Deloron P, Kortok MM, Marsh K, Daily JP, Ndiaye D, Sarr O, Mboup S, Day KP. A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa. PLoS One. 2011 Feb 09; 6(2):e16629. PMID: 21347415; PMCID: PMC3036650.
    10. O'Donnell A, Fowkes FJ, Allen SJ, Imrie H, Alpers MP, Weatherall DJ, Day KP. The acute phase response in children with mild and severe malaria in Papua New Guinea. Trans R Soc Trop Med Hyg. 2009 Jul; 103(7):679-86. PMID: 19409589.
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    11. Orengo JM, Leliwa-Sytek A, Evans JE, Evans B, van de Hoef D, Nyako M, Day K, Rodriguez A. Uric acid is a mediator of the Plasmodium falciparum-induced inflammatory response. PLoS One. 2009; 4(4):e5194. PMID: 19381275; PMCID: PMC2667251.
    12. Fowkes FJ, Day KP. Alpha+ -thalassaemia and malaria in Melanesia: epidemiological perspectives. P N G Med J. 2008 Sep-Dec; 51(3-4):131-7. PMID: 21061944.
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    13. Fowkes FJ, Allen SJ, Allen A, Alpers MP, Weatherall DJ, Day KP. Increased microerythrocyte count in homozygous alpha(+)-thalassaemia contributes to protection against severe malarial anaemia. PLoS Med. 2008 Mar 18; 5(3):e56. PMID: 18351796; PMCID: PMC2267813.
    14. Orengo JM, Evans JE, Bettiol E, Leliwa-Sytek A, Day K, Rodriguez A. Plasmodium-induced inflammation by uric acid. PLoS Pathog. 2008 Mar 07; 4(3):e1000013. PMID: 18369465; PMCID: PMC2267007.
    15. Cosgrove CL, Wood MJ, Day KP, Sheldon BC. Seasonal variation in Plasmodium prevalence in a population of blue tits Cyanistes caeruleus. J Anim Ecol. 2008 May; 77(3):540-8. PMID: 18312339.
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    16. Fowkes FJ, Michon P, Pilling L, Ripley RM, Tavul L, Imrie HJ, Woods CM, Mgone CS, Luty AJ, Day KP. Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea. Malar J. 2008 Jan 03; 7:1. PMID: 18173836; PMCID: PMC2235880.
    17. Hume JC, Tunnicliff M, Ranford-Cartwright LC, Day KP. Susceptibility of Anopheles gambiae and Anopheles stephensi to tropical isolates of Plasmodium falciparum. Malar J. 2007 Oct 24; 6:139. PMID: 17958900; PMCID: PMC2148056.
    18. Wood MJ, Cosgrove CL, Wilkin TA, Knowles SC, Day KP, Sheldon BC. Within-population variation in prevalence and lineage distribution of avian malaria in blue tits, Cyanistes caeruleus. Mol Ecol. 2007 Aug; 16(15):3263-73. PMID: 17651202.
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    19. Barry AE, Leliwa-Sytek A, Tavul L, Imrie H, Migot-Nabias F, Brown SM, McVean GA, Day KP. Population genomics of the immune evasion (var) genes of Plasmodium falciparum. PLoS Pathog. 2007 Mar; 3(3):e34. PMID: 17367208; PMCID: PMC1828697.
    20. Imrie H, Fowkes FJ, Michon P, Tavul L, Reeder JC, Day KP. Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea. Am J Trop Med Hyg. 2007 Feb; 76(2):280-4. PMID: 17297036.
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    21. Cosgrove CL, Day KP, Sheldon BC. Coamplification of Leucocytozoon by PCR diagnostic tests for avian malaria: a cautionary note. J Parasitol. 2006 Dec; 92(6):1362-5. PMID: 17304822.
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    22. Cosgrove CL, Knowles SC, Day KP, Sheldon BC. No evidence for avian malaria infection during the nestling phase in a passerine bird. J Parasitol. 2006 Dec; 92(6):1302-4. PMID: 17304811.
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    23. Volkman SK, Lozovsky E, Barry AE, Bedford T, Bethke L, Myrick A, Day KP, Hartl DL, Wirth DF, Sawyer SA. Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum. Gene. 2007 Jan 31; 387(1-2):1-6. PMID: 17005334; PMCID: PMC2593462.
    24. Imrie H, Fowkes FJ, Michon P, Tavul L, Hume JC, Piper KP, Reeder JC, Day KP. Haptoglobin levels are associated with haptoglobin genotype and alpha+ -Thalassemia in a malaria-endemic area. Am J Trop Med Hyg. 2006 Jun; 74(6):965-71. PMID: 16760505.
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    25. Barry AE, Leliwa-Sytek A, Man K, Kasper JM, Hartl DL, Day KP. Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum. Gene. 2006 Jul 19; 376(2):163-73. PMID: 16784823.
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    26. Fowkes FJ, Imrie H, Migot-Nabias F, Michon P, Justice A, Deloron P, Luty AJ, Day KP. Association of haptoglobin levels with age, parasite density, and haptoglobin genotype in a malaria-endemic area of Gabon. Am J Trop Med Hyg. 2006 Jan; 74(1):26-30. PMID: 16407342.
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    27. Mharakurwa S, Mutambu SL, Mudyiradima R, Chimbadzwa T, Chandiwana SK, Day KP. Association of house spraying with suppressed levels of drug resistance in Zimbabwe. Malar J. 2004 Oct 18; 3:35. PMID: 15491495; PMCID: PMC535889.
    28. Imrie H, Ferguson DJ, Carter M, Drain J, Schiflett A, Hajduk SL, Day KP. Light and electron microscopical observations of the effects of high-density lipoprotein on growth of Plasmodium falciparum in vitro. Parasitology. 2004 Jun; 128(Pt 6):577-84. PMID: 15206459.
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    29. Imrie H, Ferguson DJ, Day KP. Human serum haptoglobin is toxic to Plasmodium falciparum in vitro. Mol Biochem Parasitol. 2004 Jan; 133(1):93-8. PMID: 14668016.
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    30. Barry AE, Leliwa A, Choi M, Nielsen KM, Hartl DL, Day KP. DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum. Mol Biochem Parasitol. 2003 Aug 31; 130(2):143-7. PMID: 12946852.
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    31. Bruce MC, Day KP. Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea. Trends Parasitol. 2003 Jun; 19(6):271-7. PMID: 12798085.
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    32. Dyer M, Day KP. Regulation of the rate of asexual growth and commitment to sexual development by diffusible factors from in vitro cultures of Plasmodium falciparum. Am J Trop Med Hyg. 2003 Apr; 68(4):403-9. PMID: 12875287.
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    33. Hume JC, Lyons EJ, Day KP. Human migration, mosquitoes and the evolution of Plasmodium falciparum. Trends Parasitol. 2003 Mar; 19(3):144-9. PMID: 12643998.
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    34. Bruce MC, Day KP. Cross-species regulation of malaria parasitaemia in the human host. Curr Opin Microbiol. 2002 Aug; 5(4):431-7. PMID: 12160865.
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    35. Hartl DL, Volkman SK, Nielsen KM, Barry AE, Day KP, Wirth DF, Winzeler EA. The paradoxical population genetics of Plasmodium falciparum. Trends Parasitol. 2002 Jun; 18(6):266-72. PMID: 12036741.
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    36. Hayward RE, Day KP. Epitopes for modified band 3 monoclonal antibody 1C4 are not exposed on the malaria-infected red blood cell surface. Mol Biochem Parasitol. 2001 Oct; 117(2):235-9. PMID: 11606235.
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    37. Volkman SK, Barry AE, Lyons EJ, Nielsen KM, Thomas SM, Choi M, Thakore SS, Day KP, Wirth DF, Hartl DL. Recent origin of Plasmodium falciparum from a single progenitor. Science. 2001 Jul 20; 293(5529):482-4. PMID: 11463913.
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    38. Färnert A, Arez AP, Babiker HA, Beck HP, Benito A, Björkman A, Bruce MC, Conway DJ, Day KP, Henning L, Mercereau-Puijalon O, Ranford-Cartwright LC, Rubio JM, Snounou G, Walliker D, Zwetyenga J, do Rosario VE. Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study. Trans R Soc Trop Med Hyg. 2001 Mar-Apr; 95(2):225-32. PMID: 11355566.
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    39. Hayward RE, Sullivan DJ, Day KP. Plasmodium falciparum: histidine-rich protein II is expressed during gametocyte development. Exp Parasitol. 2000 Nov; 96(3):139-46. PMID: 11162364.
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    40. Anderson TJ, Su XZ, Roddam A, Day KP. Complex mutations in a high proportion of microsatellite loci from the protozoan parasite Plasmodium falciparum. Mol Ecol. 2000 Oct; 9(10):1599-608. PMID: 11050555.
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    41. Anderson TJ, Haubold B, Williams JT, Estrada-Franco JG, Richardson L, Mollinedo R, Bockarie M, Mokili J, Mharakurwa S, French N, Whitworth J, Velez ID, Brockman AH, Nosten F, Ferreira MU, Day KP. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol. 2000 Oct; 17(10):1467-82. PMID: 11018154.
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    42. Dyer M, Day K. Expression of Plasmodium falciparum trimeric G proteins and their involvement in switching to sexual development. Mol Biochem Parasitol. 2000 Oct; 110(2):437-48. PMID: 11071298.
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    43. Bruce MC, Donnelly CA, Packer M, Lagog M, Gibson N, Narara A, Walliker D, Alpers MP, Day KP. Age- and species-specific duration of infection in asymptomatic malaria infections in Papua New Guinea. Parasitology. 2000 Sep; 121 ( Pt 3):247-56. PMID: 11085245.
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    44. Bruce MC, Galinski MR, Barnwell JW, Donnelly CA, Walmsley M, Alpers MP, Walliker D, Day KP. Genetic diversity and dynamics of plasmodium falciparum and P. vivax populations in multiply infected children with asymptomatic malaria infections in Papua New Guinea. Parasitology. 2000 Sep; 121 ( Pt 3):257-72. PMID: 11085246.
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    45. Anderson TJ, Paul RE, Donnelly CA, Day KP. Do malaria parasites mate non-randomly in the mosquito midgut? Genet Res. 2000 Jun; 75(3):285-96. PMID: 10893865.
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    46. Dyer M, Day K. Expression of Plasmodium falciparum trimeric G proteins and their involvement in switching to sexual development. Mol Biochem Parasitol. 2000 Apr 30; 108(1):67-78. PMID: 10802319.
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    47. Anderson TJ, Day KP. Geographical structure and sequence evolution as inferred from the Plasmodium falciparum S-antigen locus. Mol Biochem Parasitol. 2000 Mar 05; 106(2):321-6. PMID: 10699263.
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    48. Dyer M, Day KP. Commitment to gametocytogenesis in Plasmodium falciparum. Parasitol Today. 2000 Mar; 16(3):102-7. PMID: 10689328.
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    49. Bruce MC, Donnelly CA, Alpers MP, Galinski MR, Barnwell JW, Walliker D, Day KP. Cross-species interactions between malaria parasites in humans. Science. 2000 Feb 04; 287(5454):845-8. PMID: 10657296.
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    50. Piper KP, Hayward RE, Cox MJ, Day KP. Malaria transmission and naturally acquired immunity to PfEMP-1. Infect Immun. 1999 Dec; 67(12):6369-74. PMID: 10569752; PMCID: PMC97044.
    51. Paul RE, Brockman A, Price RN, Luxemburger C, White NJ, Looareesuwan S, Nosten F, Day KP. Genetic analysis of Plasmodium falciparum infections on the north-western border of Thailand. Trans R Soc Trop Med Hyg. 1999 Nov-Dec; 93(6):587-93. PMID: 10717738.
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    52. Bruce MC, Galinski MR, Barnwell JW, Snounou G, Day KP. Polymorphism at the merozoite surface protein-3alpha locus of Plasmodium vivax: global and local diversity. Am J Trop Med Hyg. 1999 Oct; 61(4):518-25. PMID: 10548283.
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    53. Anderson TJ, Su XZ, Bockarie M, Lagog M, Day KP. Twelve microsatellite markers for characterization of Plasmodium falciparum from finger-prick blood samples. Parasitology. 1999 Aug; 119 ( Pt 2):113-25. PMID: 10466118.
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    54. Lord CC, Barnard B, Day K, Hargrove JW, McNamara JJ, Paul RE, Trenholme K, Woolhouse ME. Aggregation and distribution of strains in microparasites. Philos Trans R Soc Lond B Biol Sci. 1999 Apr 29; 354(1384):799-807. PMID: 10365405; PMCID: PMC1692560.
    55. Hayward RE, Tiwari B, Piper KP, Baruch DI, Day KP. Virulence and transmission success of the malarial parasite Plasmodium falciparum. Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8):4563-8. PMID: 10200302; PMCID: PMC16372.
    56. Piper KP, Roberts DJ, Day KP. Plasmodium falciparum: analysis of the antibody specificity to the surface of the trophozoite-infected erythrocyte. Exp Parasitol. 1999 Feb; 91(2):161-9. PMID: 9990344.
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    57. Brockman A, Paul RE, Anderson TJ, Hackford I, Phaiphun L, Looareesuwan S, Nosten F, Day KP. Application of genetic markers to the identification of recrudescent Plasmodium falciparum infections on the northwestern border of Thailand. Am J Trop Med Hyg. 1999 Jan; 60(1):14-21. PMID: 9988316.
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    58. Day KP, Hayward RE, Smith D, Culvenor JG. CD36-dependent adhesion and knob expression of the transmission stages of Plasmodium falciparum is stage specific. Mol Biochem Parasitol. 1998 Jun 01; 93(2):167-77. PMID: 9662702.
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    59. Paul RE, Hackford I, Brockman A, Muller-Graf C, Price R, Luxemburger C, White NJ, Nosten F, Day KP. Transmission intensity and Plasmodium falciparum diversity on the northwestern border of Thailand. Am J Trop Med Hyg. 1998 Feb; 58(2):195-203. PMID: 9502604.
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    60. Day KP, Hayward RE, Dyer M. The biology of Plasmodium falciparum transmission stages. Parasitology. 1998; 116 Suppl:S95-109. PMID: 9695114.
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    61. Maitland K, Williams TN, Peto TE, Day KP, Clegg JB, Weatherall DJ, Bowden DK. Absence of malaria-specific mortality in children in an area of hyperendemic malaria. Trans R Soc Trop Med Hyg. 1997 Sep-Oct; 91(5):562-6. PMID: 9463668.
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    62. Paul RE, Packer MJ, Walmsley M, Lagog M, Ranford-Cartwright LC, Paru R, Day KP. Mating patterns in malaria parasite populations of Papua New Guinea. Science. 1995 Sep 22; 269(5231):1709-11. PMID: 7569897.
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    63. Gupta S, Day KP. A strain theory of malaria transmission. Parasitol Today. 1994 Dec; 10(12):476-81. PMID: 15275516.
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    64. Mahanty S, Day KP, Alpers MP, Kazura JW. Antifilarial IgG4 antibodies in children from filaria-endemic areas correlate with duration of infection and are dissociated from antifilarial IgE antibodies. J Infect Dis. 1994 Nov; 170(5):1339-43. PMID: 7963742.
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    65. Gupta S, Day KP. A theoretical framework for the immunoepidemiology of Plasmodium falciparum malaria. Parasite Immunol. 1994 Jul; 16(7):361-70. PMID: 7970875.
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    66. Barnes DA, Thompson J, Triglia T, Day K, Kemp DJ. Mapping the genetic locus implicated in cytoadherence of Plasmodium falciparum to melanoma cells. Mol Biochem Parasitol. 1994 Jul; 66(1):21-9. PMID: 7984186.
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    67. Gupta S, Hill AV, Kwiatkowski D, Greenwood AM, Greenwood BM, Day KP. Parasite virulence and disease patterns in Plasmodium falciparum malaria. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3715-9. PMID: 8170975; PMCID: PMC43652.
    68. Cox MJ, Kum DE, Tavul L, Narara A, Raiko A, Baisor M, Alpers MP, Medley GF, Day KP. Dynamics of malaria parasitaemia associated with febrile illness in children from a rural area of Madang, Papua New Guinea. Trans R Soc Trop Med Hyg. 1994 Mar-Apr; 88(2):191-7. PMID: 8036670.
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    69. Gupta S, Trenholme K, Anderson RM, Day KP. Antigenic diversity and the transmission dynamics of Plasmodium falciparum. Science. 1994 Feb 18; 263(5149):961-3. PMID: 8310293.
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    70. Kazura J, Greenberg J, Perry R, Weil G, Day K, Alpers M. Comparison of single-dose diethylcarbamazine and ivermectin for treatment of bancroftian filariasis in Papua New Guinea. Am J Trop Med Hyg. 1993 Dec; 49(6):804-11. PMID: 8279647.
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    71. Bickle Q, Anders RF, Day K, Coppel RL. The S-antigen of Plasmodium falciparum: repertoire and origin of diversity. Mol Biochem Parasitol. 1993 Oct; 61(2):189-96. PMID: 8264723.
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    72. Day KP, Karamalis F, Thompson J, Barnes DA, Peterson C, Brown H, Brown GV, Kemp DJ. Genes necessary for expression of a virulence determinant and for transmission of Plasmodium falciparum are located on a 0.3-megabase region of chromosome 9. Proc Natl Acad Sci U S A. 1993 Sep 01; 90(17):8292-6. PMID: 8367496; PMCID: PMC47335.
    73. Kazura JW, Hazlett FE, Pearlman E, Day K, el-Zeiny A, Nilsen TW, Alpers MP. Antigenicity of a protective recombinant filarial protein in human bancroftian filariasis. J Infect Dis. 1992 Dec; 166(6):1453-7. PMID: 1431265.
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    74. Read AF, Narara A, Nee S, Keymer AE, Day KP. Gametocyte sex ratios as indirect measures of outcrossing rates in malaria. Parasitology. 1992 Jun; 104 ( Pt 3):387-95. PMID: 1641238.
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    75. Kemp DJ, Thompson J, Barnes DA, Triglia T, Karamalis F, Petersen C, Brown GV, Day KP. A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence. Mem Inst Oswaldo Cruz. 1992; 87 Suppl 3:85-9. PMID: 1343730.
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    76. Day KP, Koella JC, Nee S, Gupta S, Read AF. Population genetics and dynamics of Plasmodium falciparum: an ecological view. Parasitology. 1992; 104 Suppl:S35-52. PMID: 1589299.
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    77. Day KP, Gregory WF, Maizels RM. Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol. 1991 May; 13(3):277-90. PMID: 1852475.
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    78. Day KP, Spark R, Garner P, Raiko A, Wenger JD, Weiss N, Mitchell GF, Alpers MP, Kazura JW. Serological evaluation of the macrofilaricidal effects of diethylcarbamazine treatment in bancroftian filariasis. Am J Trop Med Hyg. 1991 May; 44(5):528-35. PMID: 2063956.
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    79. Day KP, Grenfell B, Spark R, Kazura JW, Alpers MP. Age specific patterns of change in the dynamics of Wuchereria bancrofti infection in Papua New Guinea. Am J Trop Med Hyg. 1991 May; 44(5):518-27. PMID: 2063955.
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    80. Day KP, Marsh K. Naturally acquired immunity to Plasmodium falciparum. Immunol Today. 1991 Mar; 12(3):A68-71. PMID: 2069680.
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    81. Culvenor JG, Day KP, Anders RF. Plasmodium falciparum ring-infected erythrocyte surface antigen is released from merozoite dense granules after erythrocyte invasion. Infect Immun. 1991 Mar; 59(3):1183-7. PMID: 1997422; PMCID: PMC258387.
    82. Smythe JA, Coppel RL, Day KP, Martin RK, Oduola AM, Kemp DJ, Anders RF. Structural diversity in the Plasmodium falciparum merozoite surface antigen 2. Proc Natl Acad Sci U S A. 1991 Mar 01; 88(5):1751-5. PMID: 2000383; PMCID: PMC51102.
    83. Howard RJ, Day KP. Plasmodium berghei: modification of sialic acid on red cells from infected mouse blood. Exp Parasitol. 1981 Feb; 51(1):95-103. PMID: 6257538.
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