Loading...
Header Logo
Keywords
Last Name
Institution

Professor Dyann Fergus Wirth

Title[no position]
Institution[no institution name]
Address[no address]
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wirth DF, Casamitjana N, Tanner M, Reich MR. Global action for training in malaria elimination. Malar J. 2018 Jan 25; 17(1):51. PMID: 29370810.
      View in: PubMed
    2. Daniels R, Hamilton EJ, Durfee K, Ndiaye D, Wirth DF, Hartl DL, Volkman SK. Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria. J Vis Exp. 2015 Nov 10; (105):e52839. PMID: 26575471.
      View in: PubMed
    3. Neafsey DE, Juraska M, Bedford T, Benkeser D, Valim C, Griggs A, Lievens M, Abdulla S, Adjei S, Agbenyega T, Agnandji ST, Aide P, Anderson S, Ansong D, Aponte JJ, Asante KP, Bejon P, Birkett AJ, Bruls M, Connolly KM, D'Alessandro U, Dobaño C, Gesase S, Greenwood B, Grimsby J, Tinto H, Hamel MJ, Hoffman I, Kamthunzi P, Kariuki S, Kremsner PG, Leach A, Lell B, Lennon NJ, Lusingu J, Marsh K, Martinson F, Molel JT, Moss EL, Njuguna P, Ockenhouse CF, Ogutu BR, Otieno W, Otieno L, Otieno K, Owusu-Agyei S, Park DJ, Pellé K, Robbins D, Russ C, Ryan EM, Sacarlal J, Sogoloff B, Sorgho H, Tanner M, Theander T, Valea I, Volkman SK, Yu Q, Lapierre D, Birren BW, Gilbert PB, Wirth DF. Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine. N Engl J Med. 2015 Nov 19; 373(21):2025-2037. PMID: 26488565.
      View in: PubMed
    4. Papa Mze N, Ndiaye YD, Diedhiou CK, Rahamatou S, Dieye B, Daniels RF, Hamilton EJ, Diallo M, Bei AK, Wirth DF, Mboup S, Volkman SK, Ahouidi AD, Ndiaye D. RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands. Malar J. 2015 Sep 29; 14:373. PMID: 26415927.
      View in: PubMed
    5. Pelleau S, Moss EL, Dhingra SK, Volney B, Casteras J, Gabryszewski SJ, Volkman SK, Wirth DF, Legrand E, Fidock DA, Neafsey DE, Musset L. Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt. Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37):11672-7. PMID: 26261345.
      View in: PubMed
    6. Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A. Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype. Eur J Med Chem. 2015 Sep 18; 102:320-33. PMID: 26295174.
      View in: PubMed
    7. Broadbent KM, Broadbent JC, Ribacke U, Wirth D, Rinn JL, Sabeti PC. Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA. BMC Genomics. 2015 Jun 13; 16:454. PMID: 26070627.
      View in: PubMed
    8. Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20; 7(288):288ra77. PMID: 25995223.
      View in: PubMed
    9. Daniels RF, Schaffner SF, Wenger EA, Proctor JL, Chang HH, Wong W, Baro N, Ndiaye D, Fall FB, Ndiop M, Ba M, Milner DA, Taylor TE, Neafsey DE, Volkman SK, Eckhoff PA, Hartl DL, Wirth DF. Modeling malaria genomics reveals transmission decline and rebound in Senegal. Proc Natl Acad Sci U S A. 2015 Jun 02; 112(22):7067-72. PMID: 25941365.
      View in: PubMed
    10. Hameed P S, Solapure S, Patil V, Henrich PP, Magistrado PA, Bharath S, Murugan K, Viswanath P, Puttur J, Srivastava A, Bellale E, Panduga V, Shanbag G, Awasthy D, Landge S, Morayya S, Koushik K, Saralaya R, Raichurkar A, Rautela N, Roy Choudhury N, Ambady A, Nandishaiah R, Reddy J, Prabhakar KR, Menasinakai S, Rudrapatna S, Chatterji M, Jiménez-Díaz MB, Martínez MS, Sanz LM, Coburn-Flynn O, Fidock DA, Lukens AK, Wirth DF, Bandodkar B, Mukherjee K, McLaughlin RE, Waterson D, Rosenbrier-Ribeiro L, Hickling K, Balasubramanian V, Warner P, Hosagrahara V, Dudley A, Iyer PS, Narayanan S, Kavanagh S, Sambandamurthy VK. Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate. Nat Commun. 2015 Mar 31; 6:6715. PMID: 25823686.
      View in: PubMed
    11. Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, Hamilton E, Ferreira MU, Karunaweera ND, Serre D, Zimmerman PA, Sá JM, Wellems TE, Musset L, Legrand E, Melnikov A, Neafsey DE, Volkman SK, Wirth DF, Sabeti PC. Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003539. PMID: 25781890.
      View in: PubMed
    12. Mejia P, Treviño-Villarreal JH, Hine C, Harputlugil E, Lang S, Calay E, Rogers R, Wirth D, Duraisingh MT, Mitchell JR. Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression. Nat Commun. 2015 Jan 30; 6:6050. PMID: 25636003.
      View in: PubMed
    13. Galinsky K, Valim C, Salmier A, de Thoisy B, Musset L, Legrand E, Faust A, Baniecki ML, Ndiaye D, Daniels RF, Hartl DL, Sabeti PC, Wirth DF, Volkman SK, Neafsey DE. COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data. Malar J. 2015 Jan 19; 14:4. PMID: 25599890.
      View in: PubMed
    14. Van Tyne D, Tan Y, Daily JP, Kamiza S, Seydel K, Taylor T, Mesirov JP, Wirth DF, Milner DA. Plasmodium falciparum gene expression measured directly from tissue during human infection. Genome Med. 2014; 6(11):110. PMID: 25520756.
      View in: PubMed
    15. Bei AK, Diouf A, Miura K, Larremore DB, Ribacke U, Tullo G, Moss EL, Neafsey DE, Daniels RF, Zeituni AE, Nosamiefan I, Volkman SK, Ahouidi AD, Ndiaye D, Dieye T, Mboup S, Buckee CO, Long CA, Wirth DF. Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission. Infect Immun. 2015 Jan; 83(1):276-85. PMID: 25368109.
      View in: PubMed
    16. Obaldia N, Baro NK, Calzada JE, Santamaria AM, Daniels R, Wong W, Chang HH, Hamilton EJ, Arevalo-Herrera M, Herrera S, Wirth DF, Hartl DL, Marti M, Volkman SK. Clonal outbreak of Plasmodium falciparum infection in eastern Panama. J Infect Dis. 2015 Apr 01; 211(7):1087-96. PMID: 25336725.
      View in: PubMed
    17. Lukens AK, Heidebrecht RW, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M, Schreiber SL, Wiegand RC, Wirth DF. Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors. J Infect Dis. 2015 Apr 01; 211(7):1097-103. PMID: 25336726.
      View in: PubMed
    18. Kumar AA, Lim C, Moreno Y, Mace CR, Syed A, Van Tyne D, Wirth DF, Duraisingh MT, Whitesides GM. Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers. Am J Hematol. 2015 Jan; 90(1):31-6. PMID: 25263455.
      View in: PubMed
    19. Comer E, Beaudoin JA, Kato N, Fitzgerald ME, Heidebrecht RW, Lee Md, Masi D, Mercier M, Mulrooney C, Muncipinto G, Rowley A, Crespo-Llado K, Serrano AE, Lukens AK, Wiegand RC, Wirth DF, Palmer MA, Foley MA, Munoz B, Scherer CA, Duvall JR, Schreiber SL. Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. J Med Chem. 2014 Oct 23; 57(20):8496-502. PMID: 25211597.
      View in: PubMed
    20. Hameed P S, Chinnapattu M, Shanbag G, Manjrekar P, Koushik K, Raichurkar A, Patil V, Jatheendranath S, Rudrapatna SS, Barde SP, Rautela N, Awasthy D, Morayya S, Narayan C, Kavanagh S, Saralaya R, Bharath S, Viswanath P, Mukherjee K, Bandodkar B, Srivastava A, Panduga V, Reddy J, Prabhakar KR, Sinha A, Jiménez-Díaz MB, Martínez MS, Angulo-Barturen I, Ferrer S, Sanz LM, Gamo FJ, Duffy S, Avery VM, Magistrado PA, Lukens AK, Wirth DF, Waterson D, Balasubramanian V, Iyer PS, Narayanan S, Hosagrahara V, Sambandamurthy VK, Ramachandran S. Aminoazabenzimidazoles, a novel class of orally active antimalarial agents. J Med Chem. 2014 Jul 10; 57(13):5702-13. PMID: 24914738.
      View in: PubMed
    21. Ross LS, Gamo FJ, Lafuente-Monasterio MJ, Singh OM, Rowland P, Wiegand RC, Wirth DF. In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth. J Biol Chem. 2014 Jun 27; 289(26):17980-95. PMID: 24782313.
      View in: PubMed
    22. Mharakurwa S, Daniels R, Scott A, Wirth DF, Thuma P, Volkman SK. Pre-amplification methods for tracking low-grade Plasmodium falciparum populations during scaled-up interventions in Southern Zambia. Malar J. 2014 Mar 12; 13:89. PMID: 24618119.
      View in: PubMed
    23. Bei AK, Patel SD, Volkman SK, Ahouidi AD, Ndiaye D, Mboup S, Wirth DF. An adjustable gas-mixing device to increase feasibility of in vitro culture of Plasmodium falciparum parasites in the field. PLoS One. 2014; 9(3):e90928. PMID: 24603696.
      View in: PubMed
    24. Karunaweera ND, Galappaththy GN, Wirth DF. On the road to eliminate malaria in Sri Lanka: lessons from history, challenges, gaps in knowledge and research needs. Malar J. 2014 Feb 18; 13:59. PMID: 24548783.
      View in: PubMed
    25. Gunawardena S, Ferreira MU, Kapilananda GM, Wirth DF, Karunaweera ND. The Sri Lankan paradox: high genetic diversity in Plasmodium vivax populations despite decreasing levels of malaria transmission. Parasitology. 2014 Jun; 141(7):880-90. PMID: 24533989.
      View in: PubMed
    26. Deme AB, Park DJ, Bei AK, Sarr O, Badiane AS, Gueye Pel H, Ahouidi A, Ndir O, Mboup S, Wirth DF, Ndiaye D, Volkman SK. Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests. Malar J. 2014 Jan 29; 13:34. PMID: 24472178.
      View in: PubMed
    27. Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF. A genomic and evolutionary approach reveals non-genetic drug resistance in malaria. Genome Biol. 2014; 15(11):511. PMID: 25395010.
      View in: PubMed
    28. Lukens AK, Ross LS, Heidebrecht R, Javier Gamo F, Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, Wirth DF. Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):799-804. PMID: 24381157.
      View in: PubMed
    29. Joice R, Narasimhan V, Montgomery J, Sidhu AB, Oh K, Meyer E, Pierre-Louis W, Seydel K, Milner D, Williamson K, Wiegand R, Ndiaye D, Daily J, Wirth D, Taylor T, Huttenhower C, Marti M. Inferring developmental stage composition from gene expression in human malaria. PLoS Comput Biol. 2013; 9(12):e1003392. PMID: 24348235.
      View in: PubMed
    30. Van Tyne D, Dieye B, Valim C, Daniels RF, Sène PD, Lukens AK, Ndiaye M, Bei AK, Ndiaye YD, Hamilton EJ, Ndir O, Mboup S, Volkman SK, Wirth DF, Ndiaye D. Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal. Malar J. 2013 Dec 06; 12:441. PMID: 24314037.
      View in: PubMed
    31. Chang HH, Moss EL, Park DJ, Ndiaye D, Mboup S, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, Hartl DL. Malaria life cycle intensifies both natural selection and random genetic drift. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20129-34. PMID: 24259712.
      View in: PubMed
    32. Ndiaye D, Dieye B, Ndiaye YD, Van Tyne D, Daniels R, Bei AK, Mbaye A, Valim C, Lukens A, Mboup S, Ndir O, Wirth DF, Volkman S. Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal. Int J Parasitol Drugs Drug Resist. 2013 Dec; 3:135-42. PMID: 24533303.
      View in: PubMed
    33. Hanson KK, Ressurreição AS, Buchholz K, Prudêncio M, Herman-Ornelas JD, Rebelo M, Beatty WL, Wirth DF, Hänscheid T, Moreira R, Marti M, Mota MM. Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins. Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30):E2838-47. PMID: 23836641.
      View in: PubMed
    34. Van Tyne D, Uboldi AD, Healer J, Cowman AF, Wirth DF. Modulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugs. Antimicrob Agents Chemother. 2013 Jul; 57(7):2937-41. PMID: 23587962.
      View in: PubMed
    35. Daniels R, Chang HH, Séne PD, Park DC, Neafsey DE, Schaffner SF, Hamilton EJ, Lukens AK, Van Tyne D, Mboup S, Sabeti PC, Ndiaye D, Wirth DF, Hartl DL, Volkman SK. Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal. PLoS One. 2013; 8(4):e60780. PMID: 23593309.
      View in: PubMed
    36. Coleman BI, Ribacke U, Manary M, Bei AK, Winzeler EA, Wirth DF, Duraisingh MT. Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene. Cell Host Microbe. 2012 Dec 13; 12(6):739-50. PMID: 23245319.
      View in: PubMed
    37. Badiane AS, Sarr O, Deme AB, Ahouidi AD, Gueye PE, Ndiaye M, Seck MC, Diallo M, Bei AK, Duraisingh MT, Wirth D, Ndiaye D, Ndir O, Mboup S. Distribution of erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in a hypoendemic area in Senegal. J Infect Dev Ctries. 2012 Oct 19; 6(10):727-33. PMID: 23103895.
      View in: PubMed
    38. Park DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C, Ribacke U, Van Tyne D, Galinsky K, Galligan M, Becker JS, Ndiaye D, Mboup S, Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, Volkman SK. Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):13052-7. PMID: 22826220.
      View in: PubMed
    39. Milner DA, Pochet N, Krupka M, Williams C, Seydel K, Taylor TE, Van de Peer Y, Regev A, Wirth D, Daily JP, Mesirov JP. Transcriptional profiling of Plasmodium falciparum parasites from patients with severe malaria identifies distinct low vs. high parasitemic clusters. PLoS One. 2012; 7(7):e40739. PMID: 22815802.
      View in: PubMed
    40. Chang HH, Park DJ, Galinsky KJ, Schaffner SF, Ndiaye D, Ndir O, Mboup S, Wiegand RC, Volkman SK, Sabeti PC, Wirth DF, Neafsey DE, Hartl DL. Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population. Mol Biol Evol. 2012 Nov; 29(11):3427-39. PMID: 22734050.
      View in: PubMed
    41. Ly O, Gueye PE, Deme AB, Dieng T, Badiane AS, Ahouidi AD, Diallo M, Bei AK, Wirth DF, Mboup S, Sarr O. Evolution of the pfcrt T76 and pfmdr1 Y86 markers and chloroquine susceptibility 8 years after cessation of chloroquine use in Pikine, Senegal. Parasitol Res. 2012 Oct; 111(4):1541-6. PMID: 22706959.
      View in: PubMed
    42. Amambua-Ngwa A, Park DJ, Volkman SK, Barnes KG, Bei AK, Lukens AK, Sene P, Van Tyne D, Ndiaye D, Wirth DF, Conway DJ, Neafsey DE, Schaffner SF. SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites. Mol Biol Evol. 2012 Nov; 29(11):3249-53. PMID: 22688945.
      View in: PubMed
    43. Bustamante C, Folarin OA, Gbotosho GO, Batista CN, Mesquita EA, Brindeiro RM, Tanuri A, Struchiner CJ, Sowunmi A, Oduola A, Wirth DF, Zalis MG, Happi CT. In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes. J Infect Dis. 2012 Aug 01; 206(3):324-32. PMID: 22615315.
      View in: PubMed
    44. Volkman SK, Neafsey DE, Schaffner SF, Park DJ, Wirth DF. Harnessing genomics and genome biology to understand malaria biology. Nat Rev Genet. 2012 Apr 12; 13(5):315-28. PMID: 22495435.
      View in: PubMed
    45. Daniels R, Ndiaye D, Wall M, McKinney J, Séne PD, Sabeti PC, Volkman SK, Mboup S, Wirth DF. Rapid, field-deployable method for genotyping and discovery of single-nucleotide polymorphisms associated with drug resistance in Plasmodium falciparum. Antimicrob Agents Chemother. 2012 Jun; 56(6):2976-86. PMID: 22430961.
      View in: PubMed
    46. Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M. Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nat Chem Biol. 2012 Feb 12; 8(3):311-7. PMID: 22327401.
      View in: PubMed
    47. Milner DA, Vareta J, Valim C, Montgomery J, Daniels RF, Volkman SK, Neafsey DE, Park DJ, Schaffner SF, Mahesh NC, Barnes KG, Rosen DM, Lukens AK, Van Tyne D, Wiegand RC, Sabeti PC, Seydel KB, Glover SJ, Kamiza S, Molyneux ME, Taylor TE, Wirth DF. Human cerebral malaria and Plasmodium falciparum genotypes in Malawi. Malar J. 2012 Feb 07; 11:35. PMID: 22314206.
      View in: PubMed
    48. Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chem Biol. 2011 Dec 23; 18(12):1602-10. PMID: 22195562.
      View in: PubMed
    49. Volkman SK, Ndiaye D, Diakite M, Koita OA, Nwakanma D, Daniels RF, Park DJ, Neafsey DE, Muskavitch MA, Krogstad DJ, Sabeti PC, Hartl DL, Wirth DF. Application of genomics to field investigations of malaria by the international centers of excellence for malaria research. Acta Trop. 2012 Mar; 121(3):324-32. PMID: 22182668.
      View in: PubMed
    50. Doumbia SO, Ndiaye D, Koita OA, Diakité M, Nwakanma D, Coulibaly M, Traoré SF, Keating J, Milner DA, Ndiaye JL, Sene PD, Ahouidi A, Dieye TN, Gaye O, Okebe J, Ceesay SJ, Ngwa A, Oriero EC, Konaté L, Sy N, Jawara M, Faye O, Kéita M, Cissé M, Sogoba N, Poudiougou B, Diawara S, Sangaré L, Coulibaly T, Seck I, Abubakar I, Gomis J, Mather FJ, Sissako A, Diarra A, Kandeh B, Whalen C, Moyer B, Nnedu O, Thiero O, Bei AK, Daniels R, Miura K, Long CA, Fairhurst RM, Duraisingh M, Muskavitch MA, D'Alessandro U, Conway DJ, Volkman SK, Valim C, Wirth DF, Krogstad DJ. Improving malaria control in West Africa: interruption of transmission as a paradigm shift. Acta Trop. 2012 Mar; 121(3):175-83. PMID: 22142790.
      View in: PubMed
    51. Ceesay SJ, Bojang KA, Nwakanma D, Conway DJ, Koita OA, Doumbia SO, Ndiaye D, Coulibaly TF, Diakité M, Traoré SF, Coulibaly M, Ndiaye JL, Sarr O, Gaye O, Konaté L, Sy N, Faye B, Faye O, Sogoba N, Jawara M, Dao A, Poudiougou B, Diawara S, Okebe J, Sangaré L, Abubakar I, Sissako A, Diarra A, Kéita M, Kandeh B, Long CA, Fairhurst RM, Duraisingh M, Perry R, Muskavitch MA, Valim C, Volkman SK, Wirth DF, Krogstad DJ. Sahel, savana, riverine and urban malaria in West Africa: Similar control policies with different outcomes. Acta Trop. 2012 Mar; 121(3):166-74. PMID: 22119584.
      View in: PubMed
    52. Zhang JJ, Senaratne TN, Daniels R, Valim C, Alifrangis M, Amerasinghe P, Konradsen F, Rajakaruna R, Wirth DF, Karunaweera ND. Distribution pattern of Plasmodium falciparum chloroquine transporter (pfcrt) gene haplotypes in Sri Lanka 1996-2006. Am J Trop Med Hyg. 2011 Nov; 85(5):811-4. PMID: 22049031.
      View in: PubMed
    53. Melnikov A, Galinsky K, Rogov P, Fennell T, Van Tyne D, Russ C, Daniels R, Barnes KG, Bochicchio J, Ndiaye D, Sene PD, Wirth DF, Nusbaum C, Volkman SK, Birren BW, Gnirke A, Neafsey DE. Hybrid selection for sequencing pathogen genomes from clinical samples. Genome Biol. 2011 Aug 11; 12(8):R73. PMID: 21835008.
      View in: PubMed
    54. Broadbent KM, Park D, Wolf AR, Van Tyne D, Sims JS, Ribacke U, Volkman S, Duraisingh M, Wirth D, Sabeti PC, Rinn JL. A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs. Genome Biol. 2011 Jun 20; 12(6):R56. PMID: 21689454.
      View in: PubMed
    55. Buchholz K, Burke TA, Williamson KC, Wiegand RC, Wirth DF, Marti M. A high-throughput screen targeting malaria transmission stages opens new avenues for drug development. J Infect Dis. 2011 May 15; 203(10):1445-53. PMID: 21502082.
      View in: PubMed
    56. Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr; 7(4):e1001383. PMID: 21533027.
      View in: PubMed
    57. Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jiménez-Díaz MB, Magán N, Gomez V, Ferrer S, Martínez MS, Wittlin S, Papastogiannidis P, O'Shea T, Klinger JD, Bree M, Lee E, Levine M, Wiegand RC, Munoz B, Wirth DF, Clardy J, Bathurst I, Sybertz E. Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum. Antimicrob Agents Chemother. 2011 Jun; 55(6):2612-22. PMID: 21422215.
      View in: PubMed
    58. Neafsey DE, Lawniczak MKN, Park DJ, Redmond SN, Coulibaly MB, Traoré SF, Sagnon N, Costantini C, Johnson C, Wiegand RC, Collins FH, Lander ES, Wirth DF, Kafatos FC, Besansky NJ, Christophides GK, Muskavitch MAT. SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes. Science. 2010 Oct 22; 330(6003):514-517. PMID: 20966254.
      View in: PubMed
    59. Sandhu U, Cebula M, Behme S, Riemer P, Wodarczyk C, Metzger D, Reimann J, Schirmbeck R, Hauser H, Wirth D. Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells. Nucleic Acids Res. 2011 Jan; 39(1):e1. PMID: 20935052.
      View in: PubMed
    60. Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R. A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity. Org Lett. 2010 Sep 17; 12(18):3998-4001. PMID: 20718474.
      View in: PubMed
    61. Booker ML, Bastos CM, Kramer ML, Barker RH, Skerlj R, Sidhu AB, Deng X, Celatka C, Cortese JF, Guerrero Bravo JE, Crespo Llado KN, Serrano AE, Angulo-Barturen I, Jiménez-Díaz MB, Viera S, Garuti H, Wittlin S, Papastogiannidis P, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman B, Goldsmith EJ, Phillips MA, Munoz B, Wirth DF, Klinger JD, Wiegand R, Sybertz E. Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J Biol Chem. 2010 Oct 22; 285(43):33054-64. PMID: 20702404.
      View in: PubMed
    62. Orjuela-Sánchez P, Karunaweera ND, da Silva-Nunes M, da Silva NS, Scopel KK, Gonçalves RM, Amaratunga C, Sá JM, Socheat D, Fairhust RM, Gunawardena S, Thavakodirasah T, Galapaththy GL, Abeysinghe R, Kawamoto F, Wirth DF, Ferreira MU. Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies. BMC Genet. 2010 Jul 13; 11:65. PMID: 20626846.
      View in: PubMed
    63. Zilversmit MM, Volkman SK, DePristo MA, Wirth DF, Awadalla P, Hartl DL. Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome. Mol Biol Evol. 2010 Sep; 27(9):2198-209. PMID: 20427419.
      View in: PubMed
    64. Ndiaye D, Patel V, Demas A, LeRoux M, Ndir O, Mboup S, Clardy J, Lakshmanan V, Daily JP, Wirth DF. A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal. Am J Trop Med Hyg. 2010 Feb; 82(2):228-30. PMID: 20133997.
      View in: PubMed
    65. Gunawardena S, Karunaweera ND, Ferreira MU, Phone-Kyaw M, Pollack RJ, Alifrangis M, Rajakaruna RS, Konradsen F, Amerasinghe PH, Schousboe ML, Galappaththy GN, Abeyasinghe RR, Hartl DL, Wirth DF. Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia. Am J Trop Med Hyg. 2010 Feb; 82(2):235-42. PMID: 20133999.
      View in: PubMed
    66. Wirth D, Daily J, Winzeler E, Mesirov JP, Regev A. In vivo profiles in malaria are consistent with a novel physiological state. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):E70; author reply E71-2. PMID: 19570993.
      View in: PubMed
    67. Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum. J Med Chem. 2009 Apr 23; 52(8):2185-7. PMID: 19317450.
      View in: PubMed
    68. Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF. Colorimetric high-throughput screen for detection of heme crystallization inhibitors. Antimicrob Agents Chemother. 2009 Jun; 53(6):2564-8. PMID: 19307367.
      View in: PubMed
    69. Dharia NV, Sidhu AB, Cassera MB, Westenberger SJ, Bopp SE, Eastman RT, Plouffe D, Batalov S, Park DJ, Volkman SK, Wirth DF, Zhou Y, Fidock DA, Winzeler EA. Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum. Genome Biol. 2009 Feb 13; 10(2):R21. PMID: 19216790.
      View in: PubMed
    70. Sims JS, Militello KT, Sims PA, Patel VP, Kasper JM, Wirth DF. Patterns of gene-specific and total transcriptional activity during the Plasmodium falciparum intraerythrocytic developmental cycle. Eukaryot Cell. 2009 Mar; 8(3):327-38. PMID: 19151330.
      View in: PubMed
    71. Lantos PM, Ahouidi AD, Bei AK, Jennings CV, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT. Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum. Parasitology. 2009 Jan; 136(1):1-9. PMID: 19126266.
      View in: PubMed
    72. Neafsey DE, Schaffner SF, Volkman SK, Park D, Montgomery P, Milner DA, Lukens A, Rosen D, Daniels R, Houde N, Cortese JF, Tyndall E, Gates C, Stange-Thomann N, Sarr O, Ndiaye D, Ndir O, Mboup S, Ferreira MU, Moraes Sdo L, Dash AP, Chitnis CE, Wiegand RC, Hartl DL, Birren BW, Lander ES, Sabeti PC, Wirth DF. Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence. Genome Biol. 2008; 9(12):R171. PMID: 19077304.
      View in: PubMed
    73. Happi CT, Gbotosho GO, Folarin OA, Sowunmi A, Hudson T, O'Neil M, Milhous W, Wirth DF, Oduola AM. Selection of Plasmodium falciparum multidrug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria. Antimicrob Agents Chemother. 2009 Mar; 53(3):888-95. PMID: 19075074.
      View in: PubMed
    74. Dong CK, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF. Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. Bioorg Med Chem Lett. 2009 Feb 01; 19(3):972-5. PMID: 19097788.
      View in: PubMed
    75. Nunes JK, Starnbach MN, Wirth DF. Secreted antibody is required for immunity to Plasmodium berghei. Infect Immun. 2009 Jan; 77(1):414-8. PMID: 19001073.
      View in: PubMed
    76. Daniels R, Volkman SK, Milner DA, Mahesh N, Neafsey DE, Park DJ, Rosen D, Angelino E, Sabeti PC, Wirth DF, Wiegand RC. A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking. Malar J. 2008 Oct 29; 7:223. PMID: 18959790.
      View in: PubMed
    77. Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J Biol Chem. 2008 Dec 12; 283(50):35078-85. PMID: 18842591.
      View in: PubMed
    78. Sarr O, Ahouidi AD, Ly O, Daily JP, Ndiaye D, Ndir O, Mboup S, Wirth DF. Mutations in PFCRT K76T do not correlate with sulfadoxine-pyrimethamine-amodiaquine failure in Pikine, Senegal. Parasitol Res. 2008 Sep; 103(4):765-9. PMID: 18523801.
      View in: PubMed
    79. Mazitschek R, Patel V, Wirth DF, Clardy J. Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. Bioorg Med Chem Lett. 2008 May 01; 18(9):2809-12. PMID: 18430569.
      View in: PubMed
    80. Karunaweera ND, Ferreira MU, Munasinghe A, Barnwell JW, Collins WE, King CL, Kawamoto F, Hartl DL, Wirth DF. Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene. 2008 Feb 29; 410(1):105-12. PMID: 18226474.
      View in: PubMed
    81. Daily JP, Scanfeld D, Pochet N, Le Roch K, Plouffe D, Kamal M, Sarr O, Mboup S, Ndir O, Wypij D, Levasseur K, Thomas E, Tamayo P, Dong C, Zhou Y, Lander ES, Ndiaye D, Wirth D, Winzeler EA, Mesirov JP, Regev A. Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature. 2007 Dec 13; 450(7172):1091-5. PMID: 18046333.
      View in: PubMed
    82. Bethke L, Thomas S, Walker K, Lakhia R, Rangarajan R, Wirth D. The role of DNA mismatch repair in generating genetic diversity and drug resistance in malaria parasites. Mol Biochem Parasitol. 2007 Sep; 155(1):18-25. PMID: 17583362.
      View in: PubMed
    83. Jennings CV, Ahouidi AD, Zilversmit M, Bei AK, Rayner J, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT. Molecular analysis of erythrocyte invasion in Plasmodium falciparum isolates from Senegal. Infect Immun. 2007 Jul; 75(7):3531-8. PMID: 17470537.
      View in: PubMed
    84. Gunasekera AM, Myrick A, Le Roch K, Winzeler E, Wirth DF. Plasmodium falciparum: genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment. Exp Parasitol. 2007 Sep; 117(1):87-92. PMID: 17475254.
      View in: PubMed
    85. Ferreira MU, Karunaweera ND, da Silva-Nunes M, da Silva NS, Wirth DF, Hartl DL. Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia. J Infect Dis. 2007 Apr 15; 195(8):1218-26. PMID: 17357061.
      View in: PubMed
    86. Gunasekera AM, Wickramarachchi T, Neafsey DE, Ganguli I, Perera L, Premaratne PH, Hartl D, Handunnetti SM, Udagama-Randeniya PV, Wirth DF. Genetic diversity and selection at the Plasmodium vivax apical membrane antigen-1 (PvAMA-1) locus in a Sri Lankan population. Mol Biol Evol. 2007 Apr; 24(4):939-47. PMID: 17244598.
      View in: PubMed
    87. Gunasekera AM, Myrick A, Militello KT, Sims JS, Dong CK, Gierahn T, Le Roch K, Winzeler E, Wirth DF. Regulatory motifs uncovered among gene expression clusters in Plasmodium falciparum. Mol Biochem Parasitol. 2007 May; 153(1):19-30. PMID: 17307259.
      View in: PubMed
    88. Volkman SK, Sabeti PC, DeCaprio D, Neafsey DE, Schaffner SF, Milner DA, Daily JP, Sarr O, Ndiaye D, Ndir O, Mboup S, Duraisingh MT, Lukens A, Derr A, Stange-Thomann N, Waggoner S, Onofrio R, Ziaugra L, Mauceli E, Gnerre S, Jaffe DB, Zainoun J, Wiegand RC, Birren BW, Hartl DL, Galagan JE, Lander ES, Wirth DF. A genome-wide map of diversity in Plasmodium falciparum. Nat Genet. 2007 Jan; 39(1):113-9. PMID: 17159979.
      View in: PubMed
    89. Baniecki ML, Wirth DF, Clardy J. High-throughput Plasmodium falciparum growth assay for malaria drug discovery. Antimicrob Agents Chemother. 2007 Feb; 51(2):716-23. PMID: 17116676.
      View in: PubMed
    90. Happi CT, Gbotosho GO, Folarin OA, Milner D, Sarr O, Sowunmi A, Kyle DE, Milhous WK, Wirth DF, Oduola AM. Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa. Malar J. 2006 Oct 04; 5:82. PMID: 17020611.
      View in: PubMed
    91. Volkman SK, Lozovsky E, Barry AE, Bedford T, Bethke L, Myrick A, Day KP, Hartl DL, Wirth DF, Sawyer SA. Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum. Gene. 2007 Jan 31; 387(1-2):1-6. PMID: 17005334.
      View in: PubMed
    92. Ndiaye D, Daily JP, Sarr O, Ndir O, Gaye O, Mboup S, Roper C, Wirth DF. Defining the origin of Plasmodium falciparum resistant dhfr isolates in Senegal. Acta Trop. 2006 Aug; 99(1):106-11. PMID: 16905111.
      View in: PubMed
    93. Happi CT, Gbotosho GO, Folarin OA, Sowunmi A, Bolaji OM, Fateye BA, Kyle DE, Milhous W, Wirth DF, Oduola AM. Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria. Parasitol Res. 2006 Dec; 100(1):141-8. PMID: 16874478.
      View in: PubMed
    94. Bethke LL, Zilversmit M, Nielsen K, Daily J, Volkman SK, Ndiaye D, Lozovsky ER, Hartl DL, Wirth DF. Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum. Mol Biochem Parasitol. 2006 Nov; 150(1):10-24. PMID: 16860410.
      View in: PubMed
    95. Happi CT, Gbotosho GO, Folarin OA, Bolaji OM, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. Am J Trop Med Hyg. 2006 Jul; 75(1):155-61. PMID: 16837724.
      View in: PubMed
    96. Kidgell C, Volkman SK, Daily J, Borevitz JO, Plouffe D, Zhou Y, Johnson JR, Le Roch K, Sarr O, Ndir O, Mboup S, Batalov S, Wirth DF, Winzeler EA. A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog. 2006 Jun; 2(6):e57. PMID: 16789840.
      View in: PubMed
    97. Dieng T, Bah IB, Ndiaye PM, Diallo I, Diop BM, Brasseur P, Mboup S, Wirth D, Ndir O. [In vitro evaluation of the sensitivity of Plasmodium falciparum to chloroquine using the deli-microtest in region of Dakar, Senegal]. Med Trop (Mars). 2005 Nov; 65(6):580-3. PMID: 16555520.
      View in: PubMed
    98. Ndiaye D, Daily JP, Sarr O, Ndir O, Gaye O, Mboup S, Wirth DF. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Senegal. Trop Med Int Health. 2005 Nov; 10(11):1176-9. PMID: 16262743.
      View in: PubMed
    99. Jethwaney D, Lepore T, Hassan S, Mello K, Rangarajan R, Jahnen-Dechent W, Wirth D, Sultan AA. Fetuin-A, a hepatocyte-specific protein that binds Plasmodium berghei thrombospondin-related adhesive protein: a potential role in infectivity. Infect Immun. 2005 Sep; 73(9):5883-91. PMID: 16113307.
      View in: PubMed
    100. Happi CT, Gbotosho GO, Folarin OA, Akinboye DO, Yusuf BO, Ebong OO, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria. Acta Trop. 2005 Sep; 95(3):183-93. PMID: 16023986.
      View in: PubMed
    101. Sarr O, Myrick A, Daily J, Diop BM, Dieng T, Ndir O, Sow PS, Mboup S, Wirth DF. In vivo and in vitro analysis of chloroquine resistance in Plasmodium falciparum isolates from Senegal. Parasitol Res. 2005 Sep; 97(2):136-40. PMID: 15986248.
      View in: PubMed
    102. Daily JP, Le Roch KG, Sarr O, Ndiaye D, Lukens A, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF. In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins. J Infect Dis. 2005 Apr 01; 191(7):1196-203. PMID: 15747257.
      View in: PubMed
    103. Militello KT, Patel V, Chessler AD, Fisher JK, Kasper JM, Gunasekera A, Wirth DF. RNA polymerase II synthesizes antisense RNA in Plasmodium falciparum. RNA. 2005 Apr; 11(4):365-70. PMID: 15703443.
      View in: PubMed
    104. Myrick A, Sarr O, Dieng T, Ndir O, Mboup S, Wirth DF. Analysis of the genetic diversity of the Plasmodium falciparum multidrug resistance gene 5' upstream region. Am J Trop Med Hyg. 2005 Feb; 72(2):182-8. PMID: 15741555.
      View in: PubMed
    105. Emerson LR, Skillman BC, Wolfger H, Kuchler K, Wirth DF. The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs. Ann Trop Med Parasitol. 2004 Sep; 98(6):643-9. PMID: 15324472.
      View in: PubMed
    106. Daily JP, Le Roch KG, Sarr O, Fang X, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF. In vivo transcriptional profiling of Plasmodium falciparum. Malar J. 2004 Aug 05; 3:30. PMID: 15296511.
      View in: PubMed
    107. Gunasekera AM, Patankar S, Schug J, Eisen G, Kissinger J, Roos D, Wirth DF. Widespread distribution of antisense transcripts in the Plasmodium falciparum genome. Mol Biochem Parasitol. 2004 Jul; 136(1):35-42. PMID: 15138065.
      View in: PubMed
    108. Dodge MA, Waller RF, Chow LM, Zaman MM, Cotton LM, McConville MJ, Wirth DF. Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites. Mol Microbiol. 2004 Mar; 51(6):1563-75. PMID: 15009885.
      View in: PubMed
    109. Militello KT, Dodge M, Bethke L, Wirth DF. Identification of regulatory elements in the Plasmodium falciparum genome. Mol Biochem Parasitol. 2004 Mar; 134(1):75-88. PMID: 14747145.
      View in: PubMed
    110. Happi CT, Gbotosho GO, Sowunmi A, Falade CO, Akinboye DO, Gerena L, Kyle DE, Milhous W, Wirth DF, Oduola AM. Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria. Am J Trop Med Hyg. 2004 Jan; 70(1):20-6. PMID: 14971693.
      View in: PubMed
    111. Gunasekera AM, Patankar S, Schug J, Eisen G, Wirth DF. Drug-induced alterations in gene expression of the asexual blood forms of Plasmodium falciparum. Mol Microbiol. 2003 Nov; 50(4):1229-39. PMID: 14622411.
      View in: PubMed
    112. Myrick A, Munasinghe A, Patankar S, Wirth DF. Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites. Mol Microbiol. 2003 Aug; 49(3):671-83. PMID: 12864851.
      View in: PubMed
    113. Hamoir J, Nemmar A, Halloy D, Wirth D, Vincke G, Vanderplasschen A, Nemery B, Gustin P. Effect of polystyrene particles on lung microvascular permeability in isolated perfused rabbit lungs: role of size and surface properties. Toxicol Appl Pharmacol. 2003 Aug 01; 190(3):278-85. PMID: 12902199.
      View in: PubMed
    114. Chow CS, Wirth DF. Linker scanning mutagenesis of the Plasmodium gallinaceum sexual stage specific gene pgs28 reveals a novel downstream cis-control element. Mol Biochem Parasitol. 2003 Jul; 129(2):199-208. PMID: 12850264.
      View in: PubMed
    115. Happi TC, Thomas SM, Gbotosho GO, Falade CO, Akinboye DO, Gerena L, Hudson T, Sowunmi A, Kyle DE, Milhous W, Wirth DF, Oduola AM. Point mutations in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine, among malaria patients from Nigeria. Ann Trop Med Parasitol. 2003 Jul; 97(5):439-51. PMID: 12930607.
      View in: PubMed
    116. Daily JP, Roberts C, Thomas SM, Ndir O, Dieng T, Mboup S, Wirth DF. Prevalence of Plasmodium falciparum pfcrt polymorphisms and in vitro chloroquine sensitivity in Senegal. Parasitology. 2003 May; 126(Pt 5):401-5. PMID: 12793643.
      View in: PubMed
    117. Nielsen KM, Kasper J, Choi M, Bedford T, Kristiansen K, Wirth DF, Volkman SK, Lozovsky ER, Hartl DL. Gene conversion as a source of nucleotide diversity in Plasmodium falciparum. Mol Biol Evol. 2003 May; 20(5):726-34. PMID: 12679555.
      View in: PubMed
    118. Volkman SK, Hartl DL, Wirth DF, Nielsen KM, Choi M, Batalov S, Zhou Y, Plouffe D, Le Roch KG, Abagyan R, Winzeler EA. Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum. Science. 2002 Oct 04; 298(5591):216-8. PMID: 12364807.
      View in: PubMed
    119. Wirth DF. Biological revelations. Nature. 2002 Oct 03; 419(6906):495-6. PMID: 12368862.
      View in: PubMed
    120. Militello KT, Wirth DF. A new reporter gene for transient transfection of Plasmodium falciparum. Parasitol Res. 2003 Jan; 89(2):154-7. PMID: 12489017.
      View in: PubMed
    121. Hartl DL, Volkman SK, Nielsen KM, Barry AE, Day KP, Wirth DF, Winzeler EA. The paradoxical population genetics of Plasmodium falciparum. Trends Parasitol. 2002 Jun; 18(6):266-72. PMID: 12036741.
      View in: PubMed
    122. Thomas SM, Ndir O, Dieng T, Mboup S, Wypij D, Maguire JH, Wirth DF. In vitro chloroquine susceptibility and PCR analysis of pfcrt and pfmdr1 polymorphisms in Plasmodium falciparum isolates from Senegal. Am J Trop Med Hyg. 2002 May; 66(5):474-80. PMID: 12201579.
      View in: PubMed
    123. Emerson LR, Nau ME, Martin RK, Kyle DE, Vahey M, Wirth DF. Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Antimicrob Agents Chemother. 2002 Mar; 46(3):787-96. PMID: 11850263.
      View in: PubMed
    124. Hirschmann F, Verhoeyen E, Wirth D, Bauwens S, Hauser H, Rudert M. Vital marking of articular chondrocytes by retroviral infection using green fluorescence protein. Osteoarthritis Cartilage. 2002 Feb; 10(2):109-18. PMID: 11869070.
      View in: PubMed
    125. Trouiller P, Torreele E, Olliaro P, White N, Foster S, Wirth D, Pécoul B. Drugs for neglected diseases: a failure of the market and a public health failure? Trop Med Int Health. 2001 Nov; 6(11):945-51. PMID: 11703850.
      View in: PubMed
    126. Patankar S, Munasinghe A, Shoaibi A, Cummings LM, Wirth DF. Serial analysis of gene expression in Plasmodium falciparum reveals the global expression profile of erythrocytic stages and the presence of anti-sense transcripts in the malarial parasite. Mol Biol Cell. 2001 Oct; 12(10):3114-25. PMID: 11598196.
      View in: PubMed
    127. Volkman SK, Barry AE, Lyons EJ, Nielsen KM, Thomas SM, Choi M, Thakore SS, Day KP, Wirth DF, Hartl DL. Recent origin of Plasmodium falciparum from a single progenitor. Science. 2001 Jul 20; 293(5529):482-4. PMID: 11463913.
      View in: PubMed
    128. Verhoeyen E, Hauser H, Wirth D. Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement. Hum Gene Ther. 2001 May 20; 12(8):933-44. PMID: 11387058.
      View in: PubMed
    129. Munasinghe A, Patankar S, Cook BP, Madden SL, Martin RK, Kyle DE, Shoaibi A, Cummings LM, Wirth DF. Serial analysis of gene expression (SAGE) in Plasmodium falciparum: application of the technique to A-T rich genomes. Mol Biochem Parasitol. 2001 Mar; 113(1):23-34. PMID: 11254951.
      View in: PubMed
    130. Mbacham WF, Chow CS, Daily J, Golightly LM, Wirth DF. Deletion analysis of the 5' flanking sequence of the Plasmodium gallinaceum sexual stage specific gene pgs28 suggests a bipartite arrangement of cis-control elements. Mol Biochem Parasitol. 2001 Mar; 113(1):183-7. PMID: 11254967.
      View in: PubMed
    131. Patankar S, Fujioka H, Wirth DF. The signal sequence and C-terminal hydrophobic domain are required for localization of the sexual stage antigen pgs28 to the surface of P. gallinaceum ookinetes. Mol Biochem Parasitol. 2000 Dec; 111(2):425-35. PMID: 11163448.
      View in: PubMed
    132. Vasconcelos KF, Plowe CV, Fontes CJ, Kyle D, Wirth DF, Pereira da Silva LH, Zalis MG. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase of isolates from the Amazon region of Brazil. Mem Inst Oswaldo Cruz. 2000 Sep-Oct; 95(5):721-8. PMID: 10998224.
      View in: PubMed
    133. Nau ME, Emerson LR, Martin RK, Kyle DE, Wirth DF, Vahey M. Technical assessment of the affymetrix yeast expression GeneChip YE6100 platform in a heterologous model of genes that confer resistance to antimalarial drugs in yeast. J Clin Microbiol. 2000 May; 38(5):1901-8. PMID: 10790119.
      View in: PubMed
    134. Acuna-Soto R, Maguire JH, Wirth DF. Gender distribution in asymptomatic and invasive amebiasis. Am J Gastroenterol. 2000 May; 95(5):1277-83. PMID: 10811339.
      View in: PubMed
    135. Golightly LM, Mbacham W, Daily J, Wirth DF. 3' UTR elements enhance expression of Pgs28, an ookinete protein of Plasmodium gallinaceum. Mol Biochem Parasitol. 2000 Jan 05; 105(1):61-70. PMID: 10613699.
      View in: PubMed
    136. Laserson KF, Petralanda I, Almera R, Barker RH, Spielman A, Maguire JH, Wirth DF. Genetic characterization of an epidemic of Plasmodium falciparum malaria among Yanomami Amerindians. J Infect Dis. 1999 Dec; 180(6):2081-5. PMID: 10558976.
      View in: PubMed
    137. Saiz M, Ro YT, Wirth DF, Patterson JL. Host cell proteins bind specifically to the capsid-cleaved 5' end of Leishmaniavirus RNA. J Biochem. 1999 Sep; 126(3):538-44. PMID: 10467169.
      View in: PubMed
    138. Herbst A, Koester M, Wirth D, Hauser H, Welte K. G-CSF receptor mutations in patients with severe congenital neutropenia do not abrogate Jak2 activation and stat1/stat3 translocation. Ann N Y Acad Sci. 1999 Apr 30; 872:320-5; discussion 325-7. PMID: 10372134.
      View in: PubMed
    139. Dechering KJ, Kaan AM, Mbacham W, Wirth DF, Eling W, Konings RN, Stunnenberg HG. Isolation and functional characterization of two distinct sexual-stage-specific promoters of the human malaria parasite Plasmodium falciparum. Mol Cell Biol. 1999 Feb; 19(2):967-78. PMID: 9891033.
      View in: PubMed
    140. Wirth D. Malaria: a 21st century solution for an ancient disease. Nat Med. 1998 Dec; 4(12):1360-2. PMID: 9846567.
      View in: PubMed
    141. Zalis MG, Pang L, Silveira MS, Milhous WK, Wirth DF. Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. Am J Trop Med Hyg. 1998 May; 58(5):630-7. PMID: 9598453.
      View in: PubMed
    142. Saiz M, Llanos-Cuentas A, Echevarria J, Roncal N, Cruz M, Muniz MT, Lucas C, Wirth DF, Scheffter S, Magill AJ, Patterson JL. Short report: detection of Leishmaniavirus in human biopsy samples of leishmaniasis from Peru. Am J Trop Med Hyg. 1998 Feb; 58(2):192-4. PMID: 9502603.
      View in: PubMed
    143. Volkman S, Wirth D. Functional analysis of pfmdr1 gene of Plasmodium falciparum. Methods Enzymol. 1998; 292:174-81. PMID: 9711553.
      View in: PubMed
    144. Perkins ME, Volkman S, Wirth DF, Le Blancq SM. Characterization of an ATP-binding cassette transporter in Cryptosporidium parvum. Mol Biochem Parasitol. 1997 Jul; 87(1):117-22. PMID: 9233681.
      View in: PubMed
    145. Olliaro P, Cattani J, Wirth D. Malaria, the submerged disease. JAMA. 1996 Jan 17; 275(3):230-3. PMID: 8604177.
      View in: PubMed
    146. Gueiros-Filho FJ, Viola JP, Gomes FC, Farina M, Lins U, Bertho AL, Wirth DF, Lopes UG. Leishmania amazonensis: multidrug resistance in vinblastine-resistant promastigotes is associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr1 gene. Exp Parasitol. 1995 Dec; 81(4):480-90. PMID: 8542989.
      View in: PubMed
    147. Volkman SK, Cowman AF, Wirth DF. Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8921-5. PMID: 7568044.
      View in: PubMed
    148. Stark K, Schreier E, Müller R, Wirth D, Driesel G, Bienzle U. Prevalence and determinants of anti-HCV seropositivity and of HCV genotype among intravenous drug users in Berlin. Scand J Infect Dis. 1995; 27(4):331-7. PMID: 8658065.
      View in: PubMed
    149. Wong AK, Curotto de Lafaille MA, Wirth DF. Identification of a cis-acting gene regulatory element from the lemdr1 locus of Leishmania enriettii. J Biol Chem. 1994 Oct 21; 269(42):26497-502. PMID: 7929372.
      View in: PubMed
    150. Sánchez MA, Peattie DA, Wirth D, Orozco E. Cloning, genomic organization and transcription of the Entamoeba histolytica alpha-tubulin-encoding gene. Gene. 1994 Sep 02; 146(2):239-44. PMID: 8076825.
      View in: PubMed
    151. Barker RH, Banchongaksorn T, Courval JM, Suwonkerd W, Rimwungtragoon K, Wirth DF. Plasmodium falciparum and P. vivax: factors affecting sensitivity and specificity of PCR-based diagnosis of malaria. Exp Parasitol. 1994 Aug; 79(1):41-9. PMID: 8050524.
      View in: PubMed
    152. Coutaux AF, Mooney JJ, Wirth DF. Neuronal monoamine reuptake inhibitors enhance in vitro susceptibility to chloroquine in resistant Plasmodium falciparum. Antimicrob Agents Chemother. 1994 Jun; 38(6):1419-21. PMID: 8092848.
      View in: PubMed
    153. Wong AK, Chow LM, Wirth DF. A homologous recombination strategy to analyze the vinblastine resistance property of the V-circle in Leishmania. Mol Biochem Parasitol. 1994 Mar; 64(1):75-86. PMID: 8078525.
      View in: PubMed
    154. Barker RH, Banchongaksorn T, Courval JM, Suwonkerd W, Rimwungtragoon K, Srittong N, Wirth DF. DNA probes as epidemiological tools for surveillance of Plasmodium falciparum malaria in Thailand. Int J Epidemiol. 1994 Feb; 23(1):161-8. PMID: 8194913.
      View in: PubMed
    155. Zalis MG, Wilson CM, Zhang Y, Wirth DF. Characterization of the pfmdr2 gene for Plasmodium falciparum. Mol Biochem Parasitol. 1994 Feb; 63(2):311. PMID: 7911976.
      View in: PubMed
    156. Driesel G, Wirth D, Stark K, Baumgarten R, Sucker U, Schreier E. Hepatitis C virus (HCV) genotype distribution in German isolates: studies on the sequence variability in the E2 and NS5 region. Arch Virol. 1994; 139(3-4):379-88. PMID: 7832643.
      View in: PubMed
    157. Tobin JF, Wirth DF. Mutational analysis of a signal sequence required for protein secretion in Leishmania major. Mol Biochem Parasitol. 1993 Dec; 62(2):243-9. PMID: 8139617.
      View in: PubMed
    158. Zalis MG, Wilson CM, Zhang Y, Wirth DF. Characterization of the pfmdr2 gene for Plasmodium falciparum. Mol Biochem Parasitol. 1993 Nov; 62(1):83-92. PMID: 8114829.
      View in: PubMed
    159. Chow LM, Wong AK, Ullman B, Wirth DF. Cloning and functional analysis of an extrachromosomally amplified multidrug resistance-like gene in Leishmania enriettii. Mol Biochem Parasitol. 1993 Aug; 60(2):195-208. PMID: 8232412.
      View in: PubMed
    160. Hendrickson N, Sifri CD, Henderson DM, Allen T, Wirth DF, Ullman B. Molecular characterization of the ldmdr1 multidrug resistance gene from Leishmania donovani. Mol Biochem Parasitol. 1993 Jul; 60(1):53-64. PMID: 8103567.
      View in: PubMed
    161. Iralu JV, Sritharan VK, Pieciak WS, Wirth DF, Maguire JH, Barker RH. Diagnosis of Mycobacterium avium bacteremia by polymerase chain reaction. J Clin Microbiol. 1993 Jul; 31(7):1811-4. PMID: 8349758.
      View in: PubMed
    162. Goonewardene R, Daily J, Kaslow D, Sullivan TJ, Duffy P, Carter R, Mendis K, Wirth D. Transfection of the malaria parasite and expression of firefly luciferase. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5234-6. PMID: 8506371.
      View in: PubMed
    163. Tobin JF, Reiner SL, Hatam F, Zheng S, Leptak CL, Wirth DF, Locksley RM. Transfected Leishmania expressing biologically active IFN-gamma. J Immunol. 1993 Jun 01; 150(11):5059-69. PMID: 8098724.
      View in: PubMed
    164. Volkman SK, Wilson CM, Wirth DF. Stage-specific transcripts of the Plasmodium falciparum pfmdr 1 gene. Mol Biochem Parasitol. 1993 Feb; 57(2):203-11. PMID: 8094538.
      View in: PubMed
    165. Acuna-Soto R, Samuelson J, De Girolami P, Zarate L, Millan-Velasco F, Schoolnick G, Wirth D. Application of the polymerase chain reaction to the epidemiology of pathogenic and nonpathogenic Entamoeba histolytica. Am J Trop Med Hyg. 1993 Jan; 48(1):58-70. PMID: 8427389.
      View in: PubMed
    166. Fontanet AL, Johnston DB, Walker AM, Rooney W, Thimasarn K, Sturchler D, Macdonald M, Hours M, Wirth DF. High prevalence of mefloquine-resistant falciparum malaria in eastern Thailand. Bull World Health Organ. 1993; 71(3-4):377-83. PMID: 8324857.
      View in: PubMed
    167. Wilson CM, Volkman SK, Thaithong S, Martin RK, Kyle DE, Milhous WK, Wirth DF. Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol Biochem Parasitol. 1993 Jan; 57(1):151-60. PMID: 8426608.
      View in: PubMed
    168. Curotto de Lafaille MA, Wirth DF. Creation of Null/+ mutants of the alpha-tubulin gene in Leishmania enriettii by gene cluster deletion. J Biol Chem. 1992 Nov 25; 267(33):23839-46. PMID: 1429722.
      View in: PubMed
    169. Henderson DM, Sifri CD, Rodgers M, Wirth DF, Hendrickson N, Ullman B. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene. Mol Cell Biol. 1992 Jun; 12(6):2855-65. PMID: 1350325.
      View in: PubMed
    170. Barker RH, Banchongaksorn T, Courval JM, Suwonkerd W, Rimwungtragoon K, Wirth DF. A simple method to detect Plasmodium falciparum directly from blood samples using the polymerase chain reaction. Am J Trop Med Hyg. 1992 Apr; 46(4):416-26. PMID: 1575288.
      View in: PubMed
    171. Curotto de Lafaille MA, Laban A, Wirth DF. Gene expression in Leishmania: analysis of essential 5' DNA sequences. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2703-7. PMID: 1557376.
      View in: PubMed
    172. Tobin JF, Wirth DF. A sequence insertion targeting vector for Leishmania enriettii. J Biol Chem. 1992 Mar 05; 267(7):4752-8. PMID: 1537857.
      View in: PubMed
    173. Fries JW, Patel RJ, Piessens WF, Wirth DF. Detection of untreated mycobacteria by using polymerase chain reaction and specific DNA probes. J Clin Microbiol. 1991 Aug; 29(8):1744-7. PMID: 1761699.
      View in: PubMed
    174. Tobin JF, Laban A, Wirth DF. Homologous recombination in Leishmania enriettii. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):864-8. PMID: 1992478.
      View in: PubMed
    175. Laskay T, Kiessling R, Rinke deWit TF, Wirth DF. Generation of species-specific DNA probes for Leishmania aethiopica. Mol Biochem Parasitol. 1991 Feb; 44(2):279-86. PMID: 2052028.
      View in: PubMed
    176. Rodgers MR, Popper SJ, Wirth DF. Amplification of kinetoplast DNA as a tool in the detection and diagnosis of Leishmania. Exp Parasitol. 1990 Oct; 71(3):267-75. PMID: 2170165.
      View in: PubMed
    177. Ayala P, Samuelson J, Wirth D, Orozco E. Entamoeba histolytica: physiology of multidrug resistance. Exp Parasitol. 1990 Aug; 71(2):169-75. PMID: 2373187.
      View in: PubMed
    178. Fries JW, Patel RJ, Piessens WF, Wirth DF. Genus- and species-specific DNA probes to identify mycobacteria using the polymerase chain reaction. Mol Cell Probes. 1990 Apr; 4(2):87-105. PMID: 2366764.
      View in: PubMed
    179. Laban A, Tobin JF, Curotto de Lafaille MA, Wirth DF. Stable expression of the bacterial neor gene in Leishmania enriettii. Nature. 1990 Feb 08; 343(6258):572-4. PMID: 2300209.
      View in: PubMed
    180. Samuelson J, Ayala P, Orozco E, Wirth D. Emetine-resistant mutants of Entamoeba histolytica overexpress mRNAs for multidrug resistance. Mol Biochem Parasitol. 1990 Jan 15; 38(2):281-90. PMID: 1970121.
      View in: PubMed
    181. Ayala P, Samuelson J, Wirth D, Orozco E. [Multidrug resistance in Entamoeba histolytica]. Arch Invest Med (Mex). 1990; 21 Suppl 1:103-7. PMID: 2136471.
      View in: PubMed
    182. Laban A, Wirth DF. Transfection of Leishmania enriettii and expression of chloramphenicol acetyltransferase gene. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9119-23. PMID: 2594753.
      View in: PubMed
    183. Barker RH, Brandling-Bennett AD, Koech DK, Mugambi M, Khan B, David R, David JR, Wirth DF. Plasmodium falciparum: DNA probe diagnosis of malaria in Kenya. Exp Parasitol. 1989 Oct; 69(3):226-33. PMID: 2676577.
      View in: PubMed
    184. Barker RH, Suebsaeng L, Rooney W, Wirth DF. Detection of Plasmodium falciparum infection in human patients: a comparison of the DNA probe method to microscopic diagnosis. Am J Trop Med Hyg. 1989 Sep; 41(3):266-72. PMID: 2679157.
      View in: PubMed
    185. Joseph JT, Aldritt SM, Unnasch T, Puijalon O, Wirth DF. Characterization of a conserved extrachromosomal element isolated from the avian malarial parasite Plasmodium gallinaceum. Mol Cell Biol. 1989 Sep; 9(9):3621-9. PMID: 2779561.
      View in: PubMed
    186. Aldritt SM, Joseph JT, Wirth DF. Sequence identification of cytochrome b in Plasmodium gallinaceum. Mol Cell Biol. 1989 Sep; 9(9):3614-20. PMID: 2779560.
      View in: PubMed
    187. Widmer G, Comeau AM, Furlong DB, Wirth DF, Patterson JL. Characterization of a RNA virus from the parasite Leishmania. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5979-82. PMID: 2762308.
      View in: PubMed
    188. Meredith SE, Unnasch TR, Karam M, Piessens WF, Wirth DF. Cloning and characterization of an Onchocerca volvulus specific DNA sequence. Mol Biochem Parasitol. 1989 Aug; 36(1):1-10. PMID: 2811941.
      View in: PubMed
    189. Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science. 1989 Jun 09; 244(4909):1184-6. PMID: 2658061.
      View in: PubMed
    190. Samuelson J, Acuna-Soto R, Reed S, Biagi F, Wirth D. DNA hybridization probe for clinical diagnosis of Entamoeba histolytica. J Clin Microbiol. 1989 Apr; 27(4):671-6. PMID: 2542361.
      View in: PubMed
    191. Patel RJ, Piessens WF, David JR, Wirth DF. A cloned DNA fragment for identification of Mycobacterium tuberculosis. Rev Infect Dis. 1989 Mar-Apr; 11 Suppl 2:S411-9. PMID: 2496456.
      View in: PubMed
    192. Waters AP, Unnasch TR, Wirth DF, McCutchan TF. Sequence of a small ribosomal RNA gene from Plasmodium lophurae. Nucleic Acids Res. 1989 Feb 25; 17(4):1763. PMID: 2922293.
      View in: PubMed
    193. Wirth DF, Rogers WO, Barker R, Dourado H, Suesbang L, Albuquerque B. Leishmaniasis and malaria: DNA probes for diagnosis and epidemiologic analysis. Ann N Y Acad Sci. 1989; 569:183-92. PMID: 2698086.
      View in: PubMed
    194. Lanar DE, McLaughlin GL, Wirth DF, Barker RJ, Zolg JW, Chulay JD. Comparison of thick films, in vitro culture and DNA hybridization probes for detecting Plasmodium falciparum malaria. Am J Trop Med Hyg. 1989 Jan; 40(1):3-6. PMID: 2644856.
      View in: PubMed
    195. Rogers WO, Burnheim PF, Wirth DF. Detection of Leishmania within sand flies by kinetoplast DNA hybridization. Am J Trop Med Hyg. 1988 Nov; 39(5):434-9. PMID: 2848422.
      View in: PubMed
    196. Rogers WO, Wirth DF. Generation of sequence diversity in the kinetoplast DNA minicircles of Leishmania mexicana amazonensis. Mol Biochem Parasitol. 1988 Jul; 30(1):1-8. PMID: 3398889.
      View in: PubMed
    197. Miller SI, Wirth DF. trans splicing in Leishmania enriettii and identification of ribonucleoprotein complexes containing the spliced leader and U2 equivalent RNAs. Mol Cell Biol. 1988 Jun; 8(6):2597-603. PMID: 3405214.
      View in: PubMed
    198. Shah JS, Karam M, Piessens WF, Wirth DF. Characterization of an Onchocerca-specific DNA clone from Onchocerca volvulus. Am J Trop Med Hyg. 1987 Sep; 37(2):376-84. PMID: 3661830.
      View in: PubMed
    199. Wirth DF, Barker RH. Response: malaria diagnosis. Science. 1987 Apr 03; 236(4797):12. PMID: 17759192.
      View in: PubMed
    200. Rogers WO, Wirth DF. Kinetoplast DNA minicircles: regions of extensive sequence divergence. Proc Natl Acad Sci U S A. 1987 Jan; 84(2):565-9. PMID: 3025880.
      View in: PubMed
    201. Sim BK, Shah J, Wirth DF, Piessens WF. Characterization of the filarial genome. Ciba Found Symp. 1987; 127:107-24. PMID: 2885158.
      View in: PubMed
    202. Landfear SM, Miller SI, Wirth DF. Transcriptional mapping of Leishmania enrietti tubulin mRNAs. Mol Biochem Parasitol. 1986 Dec; 21(3):235-45. PMID: 3807944.
      View in: PubMed
    203. Wirth DF, Rogers WO, Barker R, Dourado H, Suesebang L, Albuquerque B. Leishmaniasis and malaria: new tools for epidemiologic analysis. Science. 1986 Nov 21; 234(4779):975-9. PMID: 3535070.
      View in: PubMed
    204. Comeau AM, Miller SI, Wirth DF. Chromosome location of four genes in Leishmania. Mol Biochem Parasitol. 1986 Nov; 21(2):161-9. PMID: 3785294.
      View in: PubMed
    205. Miller SI, Landfear SM, Wirth DF. Cloning and characterization of a Leishmania gene encoding a RNA spliced leader sequence. Nucleic Acids Res. 1986 Sep 25; 14(18):7341-60. PMID: 2429261.
      View in: PubMed
    206. Lopes UG, Wirth DF. Identification of visceral Leishmania species with cloned sequences of kinetoplast DNA. Mol Biochem Parasitol. 1986 Jul; 20(1):77-84. PMID: 3016536.
      View in: PubMed
    207. Sim BK, Mak JW, Cheong WH, Sutanto I, Kurniawan L, Marwoto HA, Franke E, Campell JR, Wirth DF, Piessens WF, et al. Identification of Brugia malayi in vectors with a species-specific DNA probe. Am J Trop Med Hyg. 1986 May; 35(3):559-64. PMID: 3518507.
      View in: PubMed
    208. Sim BK, Piessens WF, Wirth DF. A DNA probe cloned in Escherichia coli for the identification of Brugia malayi. Mol Biochem Parasitol. 1986 May; 19(2):117-23. PMID: 2425257.
      View in: PubMed
    209. Shah JS, Lamontagne L, Unnasch TR, Wirth DF, Piessens WF. Characterization of a ribosomal DNA clone of Brugia malayi. Mol Biochem Parasitol. 1986 Apr; 19(1):67-75. PMID: 3012333.
      View in: PubMed
    210. Barker RH, Suebsaeng L, Rooney W, Alecrim GC, Dourado HV, Wirth DF. Specific DNA probe for the diagnosis of Plasmodium falciparum malaria. Science. 1986 Mar 21; 231(4744):1434-6. PMID: 3513309.
      View in: PubMed
    211. Unnasch TR, McLafferty M, Wirth DF. The primary structure of the rRNA insertions of Plasmodium lophurae. Mol Biochem Parasitol. 1985 Aug; 16(2):149-61. PMID: 2993883.
      View in: PubMed
    212. Landfear SM, Wirth DF. Structure of mRNA encoded by tubulin genes in Leishmania enriettii. Mol Biochem Parasitol. 1985 Apr; 15(1):61-82. PMID: 3990710.
      View in: PubMed
    213. Carter R, Miller LH, Rener J, Kaushal DC, Kumar N, Graves PM, Grotendorst CA, Gwadz RW, French C, Wirth D. Target antigens in malaria transmission blocking immunity. Philos Trans R Soc Lond B Biol Sci. 1984 Nov 13; 307(1131):201-13. PMID: 6151684.
      View in: PubMed
    214. Unnasch TR, Wirth DF. The cloned rRNA genes of P. lophurae: a novel rDNA structure. Nucleic Acids Res. 1983 Dec 10; 11(23):8461-72. PMID: 6324085.
      View in: PubMed
    215. Unnasch TR, Wirth DF. The avian malaria Plasmodium lophurae has a small number of heterogeneous ribosomal RNA genes. Nucleic Acids Res. 1983 Dec 10; 11(23):8443-59. PMID: 6324084.
      View in: PubMed
    216. Wirth DF, Slater C. Isolation and characterization of an alpha-tubulin gene from Leishmania enriettii. Mol Biochem Parasitol. 1983 Sep; 9(1):83-92. PMID: 6321982.
      View in: PubMed
    217. Landfear SM, McMahon-Pratt D, Wirth DF. Tandem arrangement of tubulin genes in the protozoan parasite Leishmania enriettii. Mol Cell Biol. 1983 Jun; 3(6):1070-6. PMID: 6877238.
      View in: PubMed
    218. Lodish HF, Wirth D, Porter M. Synthesis and assembly of viral membrane proteins. Ann N Y Acad Sci. 1980; 343:319-37. PMID: 6249165.
      View in: PubMed
    Wirth's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description