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Dr Helmi Mardassi

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Meftahi N, Namouchi A, Mhenni B, Brandis G, Hughes D, Mardassi H. Evidence for the critical role of a secondary site rpoB mutation in the compensatory evolution and successful transmission of an MDR tuberculosis outbreak strain. J Antimicrob Chemother. 2016 Feb; 71(2):324-32. PMID: 26538504.
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    2. Thabet S, Namouchi A, Mardassi H. Evolutionary Trends of the Transposase-Encoding Open Reading Frames A and B (orfA and orfB) of the Mycobacterial IS6110 Insertion Sequence. PLoS One. 2015; 10(6):e0130161. PMID: 26087177.
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    3. Ben Abdeljelil N, Khabouchi N, Kassar S, Miled K, Boubaker S, Ghram A, Mardassi H. Simultaneous alteration of residues 279 and 284 of the VP2 major capsid protein of a very virulent Infectious Bursal Disease Virus (vvIBDV) strain did not lead to attenuation in chickens. Virol J. 2014 Nov 25; 11:199. PMID: 25420540.
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    4. Thabet S, Karboul A, Dekhil N, Mardassi H. IS6110-5'3'FP: an automated typing approach for Mycobacterium tuberculosis complex strains simultaneously targeting and resolving IS6110 5' and 3' polymorphisms. Int J Infect Dis. 2014 Dec; 29:211-8. PMID: 25447727.
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    5. Namouchi A, Karboul A, Fabre M, Gutierrez MC, Mardassi H. Evolution of smooth tubercle Bacilli PE and PE_PGRS genes: evidence for a prominent role of recombination and imprint of positive selection. PLoS One. 2013; 8(5):e64718. PMID: 23705005.
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    6. Namouchi A, Haltiti R, Hawari D, Mardassi H. Re-emergence of the progenitors of a multidrug-resistant outbreak strain of Mycobacterium tuberculosis among the post-outbreak case patients. J Infect Dis. 2010 Feb 01; 201(3):390-8. PMID: 20021247.
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    7. Karboul A, Mazza A, Gey van Pittius NC, Ho JL, Brousseau R, Mardassi H. Frequent homologous recombination events in Mycobacterium tuberculosis PE/PPE multigene families: potential role in antigenic variability. J Bacteriol. 2008 Dec; 190(23):7838-46. PMID: 18820012.
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    8. Namouchi A, Karboul A, Mhenni B, Khabouchi N, Haltiti R, Ben Hassine R, Louzir B, Chabbou A, Mardassi H. Genetic profiling of Mycobacterium tuberculosis in Tunisia: predominance and evidence for the establishment of a few genotypes. J Med Microbiol. 2008 Jul; 57(Pt 7):864-72. PMID: 18566145.
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    9. Ben Abdeljelil N, Delmas B, Mardassi H. Replication and packaging of an infectious bursal disease virus segment A-derived minigenome. Virus Res. 2008 Sep; 136(1-2):146-51. PMID: 18562033.
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    10. Ben Abdeljelil N, Khabouchi N, Mardassi H. Efficient rescue of infectious bursal disease virus using a simplified RNA polymerase II-based reverse genetics strategy. Arch Virol. 2008; 153(6):1131-7. PMID: 18392769.
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    11. Gibson AL, Huard RC, Gey van Pittius NC, Lazzarini LC, Driscoll J, Kurepina N, Zozio T, Sola C, Spindola SM, Kritski AL, Fitzgerald D, Kremer K, Mardassi H, Chitale P, Brinkworth J, Garcia de Viedma D, Gicquel B, Pape JW, van Soolingen D, Kreiswirth BN, Warren RM, van Helden PD, Rastogi N, Suffys PN, Lapa e Silva J, Ho JL. Application of sensitive and specific molecular methods to uncover global dissemination of the major RDRio Sublineage of the Latin American-Mediterranean Mycobacterium tuberculosis spoligotype family. J Clin Microbiol. 2008 Apr; 46(4):1259-67. PMID: 18234868.
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    12. Karboul A, Gey van Pittius NC, Namouchi A, Vincent V, Sola C, Rastogi N, Suffys P, Fabre M, Cataldi A, Huard RC, Kurepina N, Kreiswirth B, Ho JL, Gutierrez MC, Mardassi H. Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair. BMC Evol Biol. 2006 Dec 12; 6:107. PMID: 17163995.
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    13. Namouchi A, Mardassi H. A genomic library-based amplification approach (GL-PCR) for the mapping of multiple IS6110 insertion sites and strain differentiation of Mycobacterium tuberculosis. J Microbiol Methods. 2006 Nov; 67(2):202-11. PMID: 16725220.
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    14. Mardassi H, Namouchi A, Haltiti R, Zarrouk M, Mhenni B, Karboul A, Khabouchi N, Gey van Pittius NC, Streicher EM, Rauzier J, Gicquel B, Dellagi K. Tuberculosis due to resistant Haarlem strain, Tunisia. Emerg Infect Dis. 2005 Jun; 11(6):957-61. PMID: 15963297.
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    15. Mardassi H, Namouchi A, Karbouli A, Khabouchi N, Haltiti R, Zarrouk M, Mhennii B, Kaabi S. Usefulness of ligation-mediated PCR genotyping in tracking outbreak-associated Mycobacterium tuberculosis strains. Arch Inst Pasteur Tunis. 2005; 82(1-4):23-9. PMID: 16929751.
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    16. Mardassi H, Khabouchi N, Ghram A, Namouchi A, Karboul A. A very virulent genotype of infectious bursal disease virus predominantly associated with recurrent infectious bursal disease outbreaks in Tunisian vaccinated flocks. Avian Dis. 2004 Dec; 48(4):829-40. PMID: 15666864.
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    17. Dea S, Gagnon CA, Mardassi H, Pirzadeh B, Rogan D. Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates. Arch Virol. 2000; 145(4):659-88. PMID: 10893147.
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    18. Mardassi H, Arfaoui A, Gribaa L, Ghram A. [Production of avian infectious bursitis virus by in vivo DNA genomic transcription]. Arch Inst Pasteur Tunis. 2000; 77(1-4):59-65. PMID: 14658230.
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    19. Mardassi H, Gonin P, Gagnon CA, Massie B, Dea S. A subset of porcine reproductive and respiratory syndrome virus GP3 glycoprotein is released into the culture medium of cells as a non-virion-associated and membrane-free (soluble) form. J Virol. 1998 Aug; 72(8):6298-306. PMID: 9658068.
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    20. Gonin P, Mardassi H, Gagnon CA, Massie B, Dea S. A nonstructural and antigenic glycoprotein is encoded by ORF3 of the IAF-Klop strain of porcine reproductive and respiratory syndrome virus. Arch Virol. 1998; 143(10):1927-40. PMID: 9856081.
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    21. Mardassi H, Massie B, Dea S. Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus. Virology. 1996 Jul 01; 221(1):98-112. PMID: 8661418.
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    22. Dea S, Gagnon CA, Mardassi H, Milane G. Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein. J Clin Microbiol. 1996 Jun; 34(6):1488-93. PMID: 8735103.
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    23. Loemba HD, Mounir S, Mardassi H, Archambault D, Dea S. Kinetics of humoral immune response to the major structural proteins of the porcine reproductive and respiratory syndrome virus. Arch Virol. 1996; 141(3-4):751-61. PMID: 8645111.
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    24. Larochelle R, Mardassi H, Dea S, Magar R. Detection of porcine reproductive and respiratory syndrome virus in cell cultures and formalin-fixed tissues by in situ hybridization using a digoxigenin-labeled probe. J Vet Diagn Invest. 1996 Jan; 8(1):3-10. PMID: 9026078.
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    25. Mardassi H, Mounir S, Dea S. Molecular analysis of the ORFs 3 to 7 of porcine reproductive and respiratory syndrome virus, Québec reference strain. Arch Virol. 1995; 140(8):1405-18. PMID: 7661693.
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    26. Mounir S, Mardassi H, Dea S. Identification and characterization of the porcine reproductive and respiratory virus ORFs 7, 5 and 4 products. Adv Exp Med Biol. 1995; 380:317-20. PMID: 8830500.
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    27. Mardassi H, Mounir S, Dea S. Structural gene analysis of a Quebec reference strain or porcine reproductive and respiratory syndrome virus (PRRSV). Adv Exp Med Biol. 1995; 380:277-81. PMID: 8830492.
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    28. Mardassi H, Wilson L, Mounir S, Dea S. Detection of porcine reproductive and respiratory syndrome virus and efficient differentiation between Canadian and European strains by reverse transcription and PCR amplification. J Clin Microbiol. 1994 Sep; 32(9):2197-203. PMID: 7814546.
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    29. Mardassi H, Mounir S, Dea S. Identification of major differences in the nucleocapsid protein genes of a Québec strain and European strains of porcine reproductive and respiratory syndrome virus. J Gen Virol. 1994 Mar; 75 ( Pt 3):681-5. PMID: 8126467.
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    30. Mardassi H, Athanassious R, Mounir S, Dea S. Porcine reproductive and respiratory syndrome virus: morphological, biochemical and serological characteristics of Quebec isolates associated with acute and chronic outbreaks of porcine reproductive and respiratory syndrome. Can J Vet Res. 1994 Jan; 58(1):55-64. PMID: 8143254.
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