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Dr Pawan Malhotra

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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kaderi Kibria KM, Rawat K, Klinger CM, Datta G, Panchal M, Singh S, Iyer GR, Kaur I, Sharma V, Dacks JB, Mohmmed A, Malhotra P. A role for adaptor protein complex 1 in protein targeting to rhoptry organelles in Plasmodium falciparum. Biochim Biophys Acta. 2015 Mar; 1853(3):699-710. PMID: 25573429.
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    2. Chugh M, Scheurer C, Sax S, Bilsland E, van Schalkwyk DA, Wicht KJ, Hofmann N, Sharma A, Bashyam S, Singh S, Oliver SG, Egan TJ, Malhotra P, Sutherland CJ, Beck HP, Wittlin S, Spangenberg T, Ding XC. Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. Antimicrob Agents Chemother. 2015 Feb; 59(2):1110-8. PMID: 25487796; PMCID: PMC4335906.
    3. Kanodia S, Kumar G, Rizzi L, Pedretti A, Hodder AN, Romeo S, Malhotra P. Synthetic peptides derived from the C-terminal 6kDa region of Plasmodium falciparum SERA5 inhibit the enzyme activity and malaria parasite development. Biochim Biophys Acta. 2014 Sep; 1840(9):2765-75. PMID: 24769454.
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    4. Sharma S, Jadli M, Singh A, Arora K, Malhotra P. A secretory multifunctional serine protease, DegP of Plasmodium falciparum, plays an important role in thermo-oxidative stress, parasite growth and development. FEBS J. 2014 Mar; 281(6):1679-99. PMID: 24494818.
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    5. Naz F, Asad M, Malhotra P, Islam A, Ahmad F, Hassan MI. Cloning, expression, purification and refolding of microtubule affinity-regulating kinase 4 expressed in Escherichia coli. Appl Biochem Biotechnol. 2014 Mar; 172(6):2838-48. PMID: 24446173.
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    6. Sachdev B, Zarin M, Khan Z, Malhotra P, Seth RK, Bhatnagar RK. Effect of gamma radiation on Phenoloxidase pathway, antioxidant defense mechanism in Helicoverpa armigera (Lepidoptera: Noctuidae) and its implication in inherited sterility towards pest suppression. Int J Radiat Biol. 2014 Jan; 90(1):7-19. PMID: 23952301.
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    7. Chugh M, Sundararaman V, Kumar S, Reddy VS, Siddiqui WA, Stuart KD, Malhotra P. Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5392-7. PMID: 23471987; PMCID: PMC3619337.
    8. Singh PK, Kanodia S, Dandin CJ, Vijayraghavan U, Malhotra P. Plasmodium falciparum Prp16 homologue and its role in splicing. Biochim Biophys Acta. 2012 Nov-Dec; 1819(11-12):1186-99. PMID: 22982196.
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    9. Patakottu BR, Singh PK, Malhotra P, Chauhan VS, Patankar S. In vivo analysis of translation initiation sites in Plasmodium falciparum. Mol Biol Rep. 2012 Mar; 39(3):2225-32. PMID: 21643747.
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    10. Rizzi L, Sundararaman S, Cendic K, Vaiana N, Korde R, Sinha D, Mohmmed A, Malhotra P, Romeo S. Design and synthesis of protein-protein interaction mimics as Plasmodium falciparum cysteine protease, falcipain-2 inhibitors. Eur J Med Chem. 2011 Jun; 46(6):2083-90. PMID: 21429631.
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    11. Ranjan R, Chugh M, Kumar S, Singh S, Kanodia S, Hossain MJ, Korde R, Grover A, Dhawan S, Chauhan VS, Reddy VS, Mohmmed A, Malhotra P. Proteome analysis reveals a large merozoite surface protein-1 associated complex on the Plasmodium falciparum merozoite surface. J Proteome Res. 2011 Feb 04; 10(2):680-91. PMID: 21175202.
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    12. Dixit A, Singh PK, Sharma GP, Malhotra P, Sharma P. PfSRPK1, a novel splicing-related kinase from Plasmodium falciparum. J Biol Chem. 2010 Dec 03; 285(49):38315-23. PMID: 20870716; PMCID: PMC2992265.
    13. Hossain MJ, Korde R, Singh PK, Kanodia S, Ranjan R, Ram G, Kalsey GS, Singh R, Malhotra P. Plasmodium falciparum Tudor Staphylococcal Nuclease interacting proteins suggest its role in nuclear as well as splicing processes. Gene. 2010 Nov 15; 468(1-2):48-57. PMID: 20713134.
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    14. Singh M, Mukherjee P, Narayanasamy K, Arora R, Sen SD, Gupta S, Natarajan K, Malhotra P. Proteome analysis of Plasmodium falciparum extracellular secretory antigens at asexual blood stages reveals a cohort of proteins with possible roles in immune modulation and signaling. Mol Cell Proteomics. 2009 Sep; 8(9):2102-18. PMID: 19494339; PMCID: PMC2742448.
    15. Gupta S, Salam N, Srivastava V, Singla R, Behera D, Khayyam KU, Korde R, Malhotra P, Saxena R, Natarajan K. Voltage gated calcium channels negatively regulate protective immunity to Mycobacterium tuberculosis. PLoS One. 2009; 4(4):e5305. PMID: 19390594; PMCID: PMC2669286.
    16. Reed ZH, Kieny MP, Engers H, Friede M, Chang S, Longacre S, Malhotra P, Pan W, Long C. Comparison of immunogenicity of five MSP1-based malaria vaccine candidate antigens in rabbits. Vaccine. 2009 Mar 04; 27(10):1651-60. PMID: 19038302.
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    17. Sunil S, Hossain MJ, Ramasamy G, Malhotra P. Transient silencing of Plasmodium falciparum Tudor Staphylococcal Nuclease suggests an essential role for the protein. Biochem Biophys Res Commun. 2008 Jul 25; 372(2):373-8. PMID: 18486605.
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    18. Sunil S, Chauhan VS, Malhotra P. Distinct and stage specific nuclear factors regulate the expression of falcipains, Plasmodium falciparum cysteine proteases. BMC Mol Biol. 2008 May 14; 9:47. PMID: 18477411; PMCID: PMC2409366.
    19. Korde R, Bhardwaj A, Singh R, Srivastava A, Chauhan VS, Bhatnagar RK, Malhotra P. A prodomain peptide of Plasmodium falciparum cysteine protease (falcipain-2) inhibits malaria parasite development. J Med Chem. 2008 Jun 12; 51(11):3116-23. PMID: 18461922.
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    20. Akhouri RR, Sharma A, Malhotra P, Sharma A. Role of Plasmodium falciparum thrombospondin-related anonymous protein in host-cell interactions. Malar J. 2008 Apr 22; 7:63. PMID: 18426606; PMCID: PMC2373790.
    21. Varshney AK, Chaudhry R, Kabra SK, Malhotra P. Cloning, expression, and immunological characterization of the P30 protein of Mycoplasma pneumoniae. Clin Vaccine Immunol. 2008 Feb; 15(2):215-20. PMID: 18032594; PMCID: PMC2238052.
    22. Hossain MJ, Korde R, Singh S, Mohmmed A, Dasaradhi PV, Chauhan VS, Malhotra P. Tudor domain proteins in protozoan parasites and characterization of Plasmodium falciparum tudor staphylococcal nuclease. Int J Parasitol. 2008 Apr; 38(5):513-26. PMID: 18035357.
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    23. Mamillapalli A, Sunil S, Diwan SS, Sharma SK, Tyagi PK, Adak T, Joshi H, Malhotra P. Polymorphism and epitope sharing between the alleles of merozoite surface protein-1 of Plasmodium falciparum among Indian isolates. Malar J. 2007 Jul 20; 6:95. PMID: 17659072; PMCID: PMC1950510.
    24. Dasaradhi PV, Korde R, Thompson JK, Tanwar C, Nag TC, Chauhan VS, Cowman AF, Mohmmed A, Malhotra P. Food vacuole targeting and trafficking of falcipain-2, an important cysteine protease of human malaria parasite Plasmodium falciparum. Mol Biochem Parasitol. 2007 Nov; 156(1):12-23. PMID: 17698213.
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    25. Rodrigues J, Agrawal N, Sharma A, Malhotra P, Adak T, Chauhan VS, Bhatnagar RK. Transcriptional analysis of an immune-responsive serine protease from Indian malarial vector, Anopheles culicifacies. BMC Mol Biol. 2007 May 15; 8:33. PMID: 17502004; PMCID: PMC1876469.
    26. Kumar A, Kumar K, Korde R, Puri SK, Malhotra P, Singh Chauhan V. Falcipain-1, a Plasmodium falciparum cysteine protease with vaccine potential. Infect Immun. 2007 Apr; 75(4):2026-34. PMID: 17242063; PMCID: PMC1865716.
    27. Ogunbanwo JA, Pendyala PR, Malhotra P, Chauhan VS. Expression, Purification and Characterization of a Recombinant Plasmodium Vivax Thrombospondin Related Adhesive Protein (PvTRAP). Int J Biomed Sci. 2006 Sep; 2(3):251-9. PMID: 23674988; PMCID: PMC3614606.
    28. Sachdeva S, Mohmmed A, Dasaradhi PV, Crabb BS, Katyal A, Malhotra P, Chauhan VS. Immunogenicity and protective efficacy of Escherichia coli expressed Plasmodium falciparum merozoite surface protein-1(42) using human compatible adjuvants. Vaccine. 2006 Mar 15; 24(12):2007-16. PMID: 16377036.
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    29. Dasaradhi PV, Mohmmed A, Kumar A, Hossain MJ, Bhatnagar RK, Chauhan VS, Malhotra P. A role of falcipain-2, principal cysteine proteases of Plasmodium falciparum in merozoite egression. Biochem Biophys Res Commun. 2005 Nov 04; 336(4):1062-8. PMID: 16165088.
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    30. Mohmmed A, Kishore S, Patra KP, Dasaradhi PV, Malhotra P, Chauhan VS. Identification of karyopherin beta as an immunogenic antigen of the malaria parasite using immune mice and human sera. Parasite Immunol. 2005 May; 27(5):197-203. PMID: 15987343.
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    31. Sachdeva S, Ahmad G, Malhotra P, Mukherjee P, Chauhan VS. Comparison of immunogenicities of recombinant Plasmodium vivax merozoite surface protein 1 19- and 42-kiloDalton fragments expressed in Escherichia coli. Infect Immun. 2004 Oct; 72(10):5775-82. PMID: 15385477; PMCID: PMC517592.
    32. Agrawal N, Malhotra P, Bhatnagar RK. siRNA-directed silencing of transgene expressed in cultured insect cells. Biochem Biophys Res Commun. 2004 Jul 23; 320(2):428-34. PMID: 15219846.
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    33. Akhouri RR, Bhattacharyya A, Pattnaik P, Malhotra P, Sharma A. Structural and functional dissection of the adhesive domains of Plasmodium falciparum thrombospondin-related anonymous protein (TRAP). Biochem J. 2004 May 01; 379(Pt 3):815-22. PMID: 14741048; PMCID: PMC1224115.
    34. Kumar A, Dasaradhi PV, Chauhan VS, Malhotra P. Exploring the role of putative active site amino acids and pro-region motif of recombinant falcipain-2: a principal hemoglobinase of Plasmodium falciparum. Biochem Biophys Res Commun. 2004 Apr 23; 317(1):38-45. PMID: 15047145.
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    35. Maestre A, Sunil S, Ahmad G, Mohmmed A, Echeverri M, Corredor M, Blair S, Chauhan VS, Malhotra P. Inter-allelic recombination in the Plasmodium vivax merozoite surface protein 1 gene among Indian and Colombian isolates. Malar J. 2004 Mar 05; 3:4. PMID: 15003129; PMCID: PMC385245.
    36. Agrawal N, Dasaradhi PV, Mohmmed A, Malhotra P, Bhatnagar RK, Mukherjee SK. RNA interference: biology, mechanism, and applications. Microbiol Mol Biol Rev. 2003 Dec; 67(4):657-85. PMID: 14665679; PMCID: PMC309050.
    37. Mohmmed A, Dasaradhi PV, Bhatnagar RK, Chauhan VS, Malhotra P. In vivo gene silencing in Plasmodium berghei--a mouse malaria model. Biochem Biophys Res Commun. 2003 Sep 26; 309(3):506-11. PMID: 12963018.
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    38. Engers H, Kieny MP, Malhotra P, Pink JR. Third meeting on Novel Adjuvants Currently in or Close to Clinical Testing World Health Organization--Organisation Mondiale de la Santé, Fondation Mérieux, Annecy, France, 7-9 January 2002. Vaccine. 2003 Sep 08; 21(25-26):3503-24. PMID: 14518430.
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    39. Chaudhry R, Nisar N, Malhotra P, Kumar A, Chauhan VS. Polymerase chain reaction confirmed Mycoplasma pneumoniae arthritis: a case report. Indian J Pathol Microbiol. 2003 Jul; 46(3):433-6. PMID: 15025294.
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    40. El Tahir A, Malhotra P, Chauhan VS. Uptake of proteins and degradation of human serum albumin by Plasmodium falciparum-infected human erythrocytes. Malar J. 2003 May 07; 2:11. PMID: 12801422; PMCID: PMC161787.
    41. Mohmmed A, Kishore S, Dasaradhi PV, Patra K, Malhotra P, Chauhan VS. Cloning and characterization of Plasmodium falciparum homologs of nuclear import factors, karyopherin alpha and karyopherin beta. Mol Biochem Parasitol. 2003 Apr 03; 127(2):199-203. PMID: 12672529.
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    42. Tuteja R, Malhotra P, Song P, Tuteja N, Chauhan VS. Isolation and characterization of an eIF-4A homologue from Plasmodium cynomolgi. Mol Biochem Parasitol. 2002 Sep-Oct; 124(1-2):79-83. PMID: 12387853.
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    43. Agrawal N, Malhotra P, Bhatnagar RK. Interaction of gene-cloned and insect cell-expressed aminopeptidase N of Spodoptera litura with insecticidal crystal protein Cry1C. Appl Environ Microbiol. 2002 Sep; 68(9):4583-92. PMID: 12200317; PMCID: PMC124070.
    44. Malhotra P, Dasaradhi PV, Kumar A, Mohmmed A, Agrawal N, Bhatnagar RK, Chauhan VS. Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum. Mol Microbiol. 2002 Sep; 45(5):1245-54. PMID: 12207693.
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    45. Kushwaha A, Rao PP, Duttu VS, Malhotra P, Chauhan VS. Expression and characterisation of Plasmodium falciparum acidic basic repeat antigen expressed in Escherichia coli. Mol Biochem Parasitol. 2000 Mar 05; 106(2):213-24. PMID: 10699251.
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    46. Sharma P, Kumar A, Singh B, Bharadwaj A, Sailaja VN, Adak T, Kushwaha A, Malhotra P, Chauhan VS. Characterization of protective epitopes in a highly conserved Plasmodium falciparum antigenic protein containing repeats of acidic and basic residues. Infect Immun. 1998 Jun; 66(6):2895-904. PMID: 9596765; PMCID: PMC108287.
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