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Dr Andrea Mara Macedo

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. de Oliveira MT, de Assis GF, Oliveira e Silva JC, Machado EM, da Silva GN, Veloso VM, Macedo AM, Martins HR, de Lana M. Trypanosoma cruzi Discret Typing Units (TcII and TcVI) in samples of patients from two municipalities of the Jequitinhonha Valley, MG, Brazil, using two molecular typing strategies. Parasit Vectors. 2015 Oct 31; 8:568. PMID: 26520576.
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    2. Reis-Cunha JL, Rodrigues-Luiz GF, Valdivia HO, Baptista RP, Mendes TA, de Morais GL, Guedes R, Macedo AM, Bern C, Gilman RH, Lopez CT, Andersson B, Vasconcelos AT, Bartholomeu DC. Chromosomal copy number variation reveals differential levels of genomic plasticity in distinct Trypanosoma cruzi strains. BMC Genomics. 2015 Jul 04; 16:499. PMID: 26141959.
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    3. Dias SR, Boroni M, Rocha EA, Dias TL, de Laet Souza D, Oliveira FM, Bitar M, Macedo AM, Machado CR, Caliari MV, Franco GR. Evaluation of the Schistosoma mansoni Y-box-binding protein (SMYB1) potential as a vaccine candidate against schistosomiasis. Front Genet. 2014; 5:174. PMID: 24966869.
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    4. Vieira HG, Grynberg P, Bitar M, Pires Sda F, Hilário HO, Macedo AM, Machado CR, de Andrade HM, Franco GR. Proteomic analysis of Trypanosoma cruzi response to ionizing radiation stress. PLoS One. 2014; 9(5):e97526. PMID: 24842666.
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    5. Ferreira KA, Fajardo EF, Baptista RP, Macedo AM, Lages-Silva E, Ramírez LE, Pedrosa AL. Species-specific markers for the differential diagnosis of Trypanosoma cruzi and Trypanosoma rangeli and polymorphisms detection in Trypanosoma rangeli. Parasitol Res. 2014 Jun; 113(6):2199-207. PMID: 24728520.
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    6. Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi. Environ Mol Mutagen. 2014 May; 55(4):309-21. PMID: 24347026.
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    7. Baptista Rde P, D'Ávila DA, Segatto M, do Valle ÍF, Franco GR, Valadares HM, Gontijo ED, Galvão LM, Pena SD, Chiari E, Machado CR, Macedo AM. Evidence of substantial recombination among Trypanosoma cruzi II strains from Minas Gerais. Infect Genet Evol. 2014 Mar; 22:183-91. PMID: 24296011.
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    8. Aguiar PH, Furtado C, Repolês BM, Ribeiro GA, Mendes IC, Peloso EF, Gadelha FR, Macedo AM, Franco GR, Pena SD, Teixeira SM, Vieira LQ, Guarneri AA, Andrade LO, Machado CR. Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability. PLoS Negl Trop Dis. 2013; 7(6):e2279. PMID: 23785540.
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    9. Furtado C, Kunrath-Lima M, Rajão MA, Mendes IC, de Moura MB, Campos PC, Macedo AM, Franco GR, Pena SD, Teixeira SM, Van Houten B, Machado CR. Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi. PLoS One. 2012; 7(8):e42484. PMID: 22876325.
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    10. Schamber-Reis BL, Nardelli S, Régis-Silva CG, Campos PC, Cerqueira PG, Lima SA, Franco GR, Macedo AM, Pena SD, Cazaux C, Hoffmann JS, Motta MC, Schenkman S, Teixeira SM, Machado CR. DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Mol Biochem Parasitol. 2012 Jun; 183(2):122-31. PMID: 22369885.
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    11. Grynberg P, Passos-Silva DG, Mourão Mde M, Hirata R, Macedo AM, Machado CR, Bartholomeu DC, Franco GR. Trypanosoma cruzi gene expression in response to gamma radiation. PLoS One. 2012; 7(1):e29596. PMID: 22247781.
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    12. Zingales B, Miles MA, Campbell DA, Tibayrenc M, Macedo AM, Teixeira MM, Schijman AG, Llewellyn MS, Lages-Silva E, Machado CR, Andrade SG, Sturm NR. The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infect Genet Evol. 2012 Mar; 12(2):240-53. PMID: 22226704.
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    13. Moreno M, D'ávila DA, Silva MN, Galvão LM, Macedo AM, Chiari E, Gontijo ED, Zingales B. Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease. Mem Inst Oswaldo Cruz. 2010 Nov; 105(7):918-24. PMID: 21120364.
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    14. Andrade LO, Galvão LM, Meirelles Mde N, Chiari E, Pena SD, Macedo AM. Differential tissue tropism of Trypanosoma cruzi strains: an in vitro study. Mem Inst Oswaldo Cruz. 2010 Sep; 105(6):834-7. PMID: 20945002.
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    15. Albertti LA, Macedo AM, Chiari E, Andrews NW, Andrade LO. Role of host lysosomal associated membrane protein (LAMP) in Trypanosoma cruzi invasion and intracellular development. Microbes Infect. 2010 Sep; 12(10):784-9. PMID: 20561595.
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    16. Mantilla JC, Zafra GA, Macedo AM, González CI. Mixed infection of Trypanosoma cruzi I and II in a Colombian cardiomyopathic patient. Hum Pathol. 2010 Apr; 41(4):610-3. PMID: 20153511.
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    17. Carranza JC, Valadares HM, D'Avila DA, Baptista RP, Moreno M, Galvão LM, Chiari E, Sturm NR, Gontijo ED, Macedo AM, Zingales B. Trypanosoma cruzi maxicircle heterogeneity in Chagas disease patients from Brazil. Int J Parasitol. 2009 Jul 15; 39(9):963-73. PMID: 19504756.
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    18. Freitas JM, Andrade LO, Pires SF, Lima R, Chiari E, Santos RR, Soares M, Machado CR, Franco GR, Pena SD, Macedo AM. The MHC gene region of murine hosts influences the differential tissue tropism of infecting Trypanosoma cruzi strains. PLoS One. 2009; 4(4):e5113. PMID: 19337367.
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    19. Zafra G, Mantilla JC, Valadares HM, Macedo AM, González CI. Evidence of Trypanosoma cruzi II infection in Colombian chagasic patients. Parasitol Res. 2008 Aug; 103(3):731-4. PMID: 18523803.
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    20. Burgos JM, Begher S, Silva HM, Bisio M, Duffy T, Levin MJ, Macedo AM, Schijman AG. Molecular identification of Trypanosoma cruzi I tropism for central nervous system in Chagas reactivation due to AIDS. Am J Trop Med Hyg. 2008 Feb; 78(2):294-7. PMID: 18256432.
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    21. Burgos JM, Altcheh J, Bisio M, Duffy T, Valadares HM, Seidenstein ME, Piccinali R, Freitas JM, Levin MJ, Macchi L, Macedo AM, Freilij H, Schijman AG. Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease. Int J Parasitol. 2007 Oct; 37(12):1319-27. PMID: 17570369.
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    22. Lages-Silva E, Ramírez LE, Pedrosa AL, Crema E, da Cunha Galvão LM, Pena SD, Macedo AM, Chiari E. Variability of kinetoplast DNA gene signatures of Trypanosoma cruzi II strains from patients with different clinical forms of Chagas' disease in Brazil. J Clin Microbiol. 2006 Jun; 44(6):2167-71. PMID: 16757616.
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    23. Burgos JM, Begher SB, Freitas JM, Bisio M, Duffy T, Altcheh J, Teijeiro R, Lopez Alcoba H, Deccarlini F, Freilij H, Levin MJ, Levalle J, Macedo AM, Schijman AG. Molecular diagnosis and typing of Trypanosoma cruzi populations and lineages in cerebral Chagas disease in a patient with AIDS. Am J Trop Med Hyg. 2005 Dec; 73(6):1016-8. PMID: 16354804.
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    24. Macedo AM, Machado CR, Oliveira RP, Pena SD. Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of chagas disease. Mem Inst Oswaldo Cruz. 2004 Feb; 99(1):1-12. PMID: 15057339.
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    25. DaRocha WD, Silva RA, Bartholomeu DC, Pires SF, Freitas JM, Macedo AM, Vazquez MP, Levin MJ, Teixeira SM. Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols. Parasitol Res. 2004 Jan; 92(2):113-20. PMID: 14634799.
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    26. Macedo AM, Oliveira RP, Pena SD. Chagas disease: role of parasite genetic variation in pathogenesis. Expert Rev Mol Med. 2002 Mar 05; 4(5):1-16. PMID: 14987389.
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    27. Lages-Silva E, Crema E, Ramirez LE, Macedo AM, Pena SD, Chiari E. Relationship between Trypanosoma cruzi and human chagasic megaesophagus: blood and tissue parasitism. Am J Trop Med Hyg. 2001 Nov; 65(5):435-41. PMID: 11716095.
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    28. Macedo AM, Pimenta JR, Aguiar RS, Melo AI, Chiari E, Zingales B, Pena SD, Oliveira RP. Usefulness of microsatellite typing in population genetic studies of Trypanosoma cruzi. Mem Inst Oswaldo Cruz. 2001 Apr; 96(3):407-13. PMID: 11313654.
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    29. Vago AR, Andrade LO, Leite AA, d'Avila Reis D, Macedo AM, Adad SJ, Tostes S, Moreira MC, Filho GB, Pena SD. Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic Chagas disease: differential distribution of genetic types into diverse organs. Am J Pathol. 2000 May; 156(5):1805-9. PMID: 10793092.
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    30. Zingales B, Pereira ME, Oliveira RP, Almeida KA, Umezawa ES, Souto RP, Vargas N, Cano MI, da Silveira JF, Nehme NS, Morel CM, Brener Z, Macedo A. Trypanosoma cruzi genome project: biological characteristics and molecular typing of clone CL Brener. Acta Trop. 1997 Nov; 68(2):159-73. PMID: 9386791.
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