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Dr Pauline Ngina Mutie Mwinzi

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ezeamama AE, He CL, Shen Y, Yin XP, Binder SC, Campbell CH, Rathbun S, Whalen CC, N'Goran EK, Utzinger J, Olsen A, Magnussen P, Kinung'hi S, Fenwick A, Phillips A, Ferro J, Karanja DM, Mwinzi PN, Montgomery S, Secor WE, Hamidou A, Garba A, King CH, Colley DG. Gaining and sustaining schistosomiasis control: study protocol and baseline data prior to different treatment strategies in five African countries. BMC Infect Dis. 2016 05 26; 16:229. PMID: 27230666.
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    2. Mwinzi PN, Muchiri G, Wiegand RE, Omedo M, Abudho B, Karanja DM, Montgomery SP, Secor WE. Predictive Value of School-Aged Children's Schistosomiasis Prevalence and Egg Intensity for Other Age Groups in Western Kenya. Am J Trop Med Hyg. 2015 Dec; 93(6):1311-7. PMID: 26416108.
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    3. Kepha S, Nuwaha F, Nikolay B, Gichuki P, Mwandawiro CS, Mwinzi PN, Odiere MR, Edwards T, Allen E, Brooker SJ. Effect of Repeated Anthelminthic Treatment on Malaria in School Children in Kenya: A Randomized, Open-Label, Equivalence Trial. J Infect Dis. 2016 Jan 15; 213(2):266-75. PMID: 26170395.
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    4. Lai YS, Biedermann P, Ekpo UF, Garba A, Mathieu E, Midzi N, Mwinzi P, N'Goran EK, Raso G, Assaré RK, Sacko M, Schur N, Talla I, Tchuenté LA, Touré S, Winkler MS, Utzinger J, Vounatsou P. Spatial distribution of schistosomiasis and treatment needs in sub-Saharan Africa: a systematic review and geostatistical analysis. Lancet Infect Dis. 2015 Aug; 15(8):927-40. PMID: 26004859.
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    5. Corstjens PL, Nyakundi RK, de Dood CJ, Kariuki TM, Ochola EA, Karanja DM, Mwinzi PN, van Dam GJ. Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes. Parasit Vectors. 2015 Apr 22; 8:241. PMID: 25896512.
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    6. Worrell CM, Bartoces M, Karanja DM, Ochola EA, Matete DO, Mwinzi PN, Montgomery SP, Secor WE. Cost analysis of tests for the detection of Schistosoma mansoni infection in children in western Kenya. Am J Trop Med Hyg. 2015 Jun; 92(6):1233-9. PMID: 25870422.
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    7. Foo KT, Blackstock AJ, Ochola EA, Matete DO, Mwinzi PN, Montgomery SP, Karanja DM, Secor WE. Evaluation of point-of-contact circulating cathodic antigen assays for the detection of Schistosoma mansoni infection in low-, moderate-, and high-prevalence schools in western Kenya. Am J Trop Med Hyg. 2015 Jun; 92(6):1227-32. PMID: 25870418.
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    8. Griffith Q, Liang Y, Whitworth P, Rodriguez-Russo C, Gul A, Siddiqui AA, Connor J, Mwinzi P, Ganley-Leal L. Immuno-evasive tactics by schistosomes identify an effective allergy preventative. Exp Parasitol. 2015 Jun; 153:139-50. PMID: 25819297.
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    9. Mwinzi PN, Kittur N, Ochola E, Cooper PJ, Campbell CH, King CH, Colley DG. Additional Evaluation of the Point-of-Contact Circulating Cathodic Antigen Assay for Schistosoma mansoni Infection. Front Public Health. 2015; 3:48. PMID: 25853117.
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    10. Karagiannis-Voules DA, Biedermann P, Ekpo UF, Garba A, Langer E, Mathieu E, Midzi N, Mwinzi P, Polderman AM, Raso G, Sacko M, Talla I, Tchuenté LA, Touré S, Winkler MS, Utzinger J, Vounatsou P. Spatial and temporal distribution of soil-transmitted helminth infection in sub-Saharan Africa: a systematic review and geostatistical meta-analysis. Lancet Infect Dis. 2015 Jan; 15(1):74-84. PMID: 25486852.
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    11. Omedo M, Ogutu M, Awiti A, Musuva R, Muchiri G, Montgomery SP, Secor WE, Mwinzi P. The effect of a health communication campaign on compliance with mass drug administration for schistosomiasis control in western Kenya--the SCORE project. Am J Trop Med Hyg. 2014 Nov; 91(5):982-8. PMID: 25246690.
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    12. Ogola GO, Ouma C, Jura WG, Muok EO, Colebunders R, Mwinzi PN. A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory Syndrome in a Kenyan population. BMC Infect Dis. 2014 Jun 10; 14:316. PMID: 24912586.
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    13. Odhiambo GO, Musuva RM, Atuncha VO, Mutete ET, Odiere MR, Onyango RO, Alaii JA, Mwinzi PN. Low levels of awareness despite high prevalence of schistosomiasis among communities in Nyalenda informal settlement, Kisumu city, western Kenya. PLoS Negl Trop Dis. 2014 Apr; 8(4):e2784. PMID: 24699502.
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    14. Sang HC, Muchiri G, Ombok M, Odiere MR, Mwinzi PN. Schistosoma haematobium hotspots in south Nyanza, western Kenya: prevalence, distribution and co-endemicity with Schistosoma mansoni and soil-transmitted helminths. Parasit Vectors. 2014 Mar 25; 7:125. PMID: 24667030.
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    15. Musuva RM, Awiti A, Omedo M, Ogutu M, Secor WE, Montgomery SP, Alaii J, Mwinzi PN. Community knowledge, attitudes and practices on schistosomiasis in western Kenya--the SCORE Project. Am J Trop Med Hyg. 2014 Apr; 90(4):646-52. PMID: 24534810.
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    16. Won KY, Abudho B, Blackstock AJ, Montgomery SP, Kennedy ED, Person B, Mwinzi PN, Ochola EA, Foo KT, Hightower AW, Karanja DM, Secor WE. Assessment of quality of life as a tool for measuring morbidity due to Schistosoma mansoni infection and the impact of treatment. Am J Trop Med Hyg. 2014 Feb; 90(2):322-8. PMID: 24323511.
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    17. Muok EM, Simiyu EW, Ochola EA, Ng'ang'a ZW, Secor WE, Karanja DM, Mwinzi PN. Association between CD4+ T-lymphocyte counts and fecal excretion of Schistosoma mansoni eggs in patients coinfected with S. mansoni and human immunodeficiency virus before and after initiation of antiretroviral therapy. Am J Trop Med Hyg. 2013 Jul; 89(1):42-5. PMID: 23669231.
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    18. Odiere MR, Rawago FO, Ombok M, Secor WE, Karanja DM, Mwinzi PN, Lammie PJ, Won K. High prevalence of schistosomiasis in Mbita and its adjacent islands of Lake Victoria, western Kenya. Parasit Vectors. 2012 Dec 03; 5:278. PMID: 23206383.
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    19. Omedo MO, Matey EJ, Awiti A, Ogutu M, Alaii J, Karanja DM, Montgomery SP, Secor WE, Mwinzi PN. Community health workers' experiences and perspectives on mass drug administration for schistosomiasis control in western Kenya: the SCORE Project. Am J Trop Med Hyg. 2012 Dec; 87(6):1065-72. PMID: 23091190.
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    20. Samuels AM, Matey E, Mwinzi PN, Wiegand RE, Muchiri G, Ireri E, Hyde M, Montgomery SP, Karanja DM, Secor WE. Schistosoma mansoni morbidity among school-aged children: a SCORE project in Kenya. Am J Trop Med Hyg. 2012 Nov; 87(5):874-82. PMID: 22987651.
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    21. Mwinzi PN, Montgomery SP, Owaga CO, Mwanje M, Muok EM, Ayisi JG, Laserson KF, Muchiri EM, Secor WE, Karanja DM. Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya - a pilot study. Parasit Vectors. 2012 Aug 31; 5:182. PMID: 22937890.
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    22. Opisa S, Odiere MR, Jura WG, Karanja DM, Mwinzi PN. Faecal contamination of public water sources in informal settlements of Kisumu City, western Kenya. Water Sci Technol. 2012; 66(12):2674-81. PMID: 23109585.
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    23. Opisa S, Odiere MR, Jura WG, Karanja DM, Mwinzi PN. Malacological survey and geographical distribution of vector snails for schistosomiasis within informal settlements of Kisumu City, western Kenya. Parasit Vectors. 2011 Dec 07; 4:226. PMID: 22152486.
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    24. Ahmad G, Zhang W, Torben W, Ahrorov A, Damian RT, Wolf RF, White GL, Carey DW, Mwinzi PN, Ganley-Leal L, Kennedy RC, Siddiqui AA. Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic. J Infect Dis. 2011 Nov; 204(9):1437-49. PMID: 21921206.
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    25. Onguru D, Liang Y, Elliot J, Mwinzi P, Ganley-Leal L. CD23b isoform expression in human schistosomiasis identifies a novel subset of activated B cells. Infect Immun. 2011 Sep; 79(9):3770-7. PMID: 21708991.
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    26. Odiere MR, Opisa S, Odhiambo G, Jura WG, Ayisi JM, Karanja DM, Mwinzi PN. Geographical distribution of schistosomiasis and soil-transmitted helminths among school children in informal settlements in Kisumu City, Western Kenya. Parasitology. 2011 Oct; 138(12):1569-77. PMID: 21679486.
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    27. Verani JR, Abudho B, Montgomery SP, Mwinzi PN, Shane HL, Butler SE, Karanja DM, Secor WE. Schistosomiasis among young children in Usoma, Kenya. Am J Trop Med Hyg. 2011 May; 84(5):787-91. PMID: 21540390.
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    28. Manivannan B, Rawson P, Jordan TW, Karanja DM, Mwinzi PN, Secor WE, La Flamme AC. Identification of cytokeratin 18 as a biomarker of mouse and human hepatosplenic schistosomiasis. Infect Immun. 2011 May; 79(5):2051-8. PMID: 21357724.
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    29. Onguru D, Liang Y, Griffith Q, Nikolajczyk B, Mwinzi P, Ganley-Leal L. Human schistosomiasis is associated with endotoxemia and Toll-like receptor 2- and 4-bearing B cells. Am J Trop Med Hyg. 2011 Feb; 84(2):321-4. PMID: 21292908.
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    30. Shane HL, Verani JR, Abudho B, Montgomery SP, Blackstock AJ, Mwinzi PN, Butler SE, Karanja DM, Secor WE. Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya. PLoS Negl Trop Dis. 2011 Jan 25; 5(1):e951. PMID: 21283613.
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    31. Griffith QK, Liang Y, Onguru DO, Mwinzi PN, Ganley-Leal LM. CD23-bound IgE augments and dominates recall responses through human naive B cells. J Immunol. 2011 Jan 15; 186(2):1060-7. PMID: 21160045.
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    32. Black CL, Muok EM, Mwinzi PN, Carter JM, Karanja DM, Secor WE, Colley DG. Increases in levels of schistosome-specific immunoglobulin E and CD23(+) B cells in a cohort of Kenyan children undergoing repeated treatment and reinfection with Schistosoma mansoni. J Infect Dis. 2010 Aug 15; 202(3):399-405. PMID: 20560767.
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    33. Obonyo CO, Muok EM, Mwinzi PN. Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial. Lancet Infect Dis. 2010 Sep; 10(9):603-11. PMID: 20705516.
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    34. Black CL, Mwinzi PN, Muok EM, Abudho B, Fitzsimmons CM, Dunne DW, Karanja DM, Secor WE, Colley DG. Influence of exposure history on the immunology and development of resistance to human Schistosomiasis mansoni. PLoS Negl Trop Dis. 2010 Mar 23; 4(3):e637. PMID: 20351784.
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    35. Muok EM, Mouk EM, Mwinzi PN, Black CL, Carter JM, Ng'ang'a ZW, Gicheru MM, Secor WE, Karanja DM, Colley DG. Short report: Childhood coinfections with Plasmodium falciparum and Schistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than schistosomiasis only. Am J Trop Med Hyg. 2009 Mar; 80(3):475-8. PMID: 19270301.
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    36. Black CL, Steinauer ML, Mwinzi PN, Evan Secor W, Karanja DM, Colley DG. Impact of intense, longitudinal retreatment with praziquantel on cure rates of schistosomiasis mansoni in a cohort of occupationally exposed adults in western Kenya. Trop Med Int Health. 2009 Apr; 14(4):450-7. PMID: 19222824.
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    37. Gatlin MR, Black CL, Mwinzi PN, Secor WE, Karanja DM, Colley DG. Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni. PLoS Negl Trop Dis. 2009; 3(2):e375. PMID: 19190772.
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    38. Mwinzi PN, Ganley-Leal L, Black CL, Secor WE, Karanja DM, Colley DG. Circulating CD23+ B cell subset correlates with the development of resistance to Schistosoma mansoni reinfection in occupationally exposed adults who have undergone multiple treatments. J Infect Dis. 2009 Jan 15; 199(2):272-9. PMID: 19072134.
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    39. Obonyo CO, Omondi DS, Mwinzi PN. Public-health crisis after the election violence in Kenya. Lancet. 2008 Apr 19; 371(9621):1319-21. PMID: 18424311.
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    40. Watanabe K, Mwinzi PN, Black CL, Muok EM, Karanja DM, Secor WE, Colley DG. T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment. Am J Trop Med Hyg. 2007 Oct; 77(4):676-82. PMID: 17978070.
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    41. Ganley-Leal LM, Mwinzi PN, Cetre-Sossah CB, Andove J, Hightower AW, Karanja DM, Colley DG, Secor WE. Higher percentages of circulating mast cell precursors correlate with susceptibility to reinfection with Schistosoma mansoni. Am J Trop Med Hyg. 2006 Dec; 75(6):1053-7. PMID: 17172364.
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    42. Ganley-Leal LM, Mwinzi PN, Cetre-Sossah CB, Andove J, Hightower AW, Karanja DM, Colley DG, Secor WE. Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans. Infect Immun. 2006 Apr; 74(4):2169-76. PMID: 16552047.
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    43. van der Flier M, Coenjaerts FE, Mwinzi PN, Rijkers E, Ruyken M, Scharringa J, Kimpen JL, Hoepelman AI, Geelen SP. Antibody neutralization of vascular endothelial growth factor (VEGF) fails to attenuate vascular permeability and brain edema in experimental pneumococcal meningitis. J Neuroimmunol. 2005 Mar; 160(1-2):170-7. PMID: 15710470.
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    44. Mwinzi PN, Karanja DM, Kareko I, Magak PW, Orago AS, Colley DG, Secor WE. Short report: Evaluation of hepatic fibrosis in persons co-infected with Schistosoma mansoni and human immunodeficiency virus 1. Am J Trop Med Hyg. 2004 Dec; 71(6):783-6. PMID: 15642972.
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    45. Coenjaerts FE, van der Flier M, Mwinzi PN, Brouwer AE, Scharringa J, Chaka WS, Aarts M, Rajanuwong A, van de Vijver DA, Harrison TS, Hoepelman AI. Intrathecal production and secretion of vascular endothelial growth factor during Cryptococcal Meningitis. J Infect Dis. 2004 Oct 01; 190(7):1310-7. PMID: 15346343.
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    46. Karanja DM, Hightower AW, Colley DG, Mwinzi PN, Galil K, Andove J, Secor WE. Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: a longitudinal study. Lancet. 2002 Aug 24; 360(9333):592-6. PMID: 12241930.
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    47. Coenjaerts FE, Walenkamp AM, Mwinzi PN, Scharringa J, Dekker HA, van Strijp JA, Cherniak R, Hoepelman AI. Potent inhibition of neutrophil migration by cryptococcal mannoprotein-4-induced desensitization. J Immunol. 2001 Oct 01; 167(7):3988-95. PMID: 11564818.
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    48. Mwinzi PN, Karanja DM, Colley DG, Orago AS, Secor WE. Cellular immune responses of schistosomiasis patients are altered by human immunodeficiency virus type 1 coinfection. J Infect Dis. 2001 Aug 15; 184(4):488-96. PMID: 11471107.
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