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Professor Dr Charles William Jefford

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Jefford CW. Synthetic peroxides as potent antimalarials. News and views. Curr Top Med Chem. 2012; 12(5):373-99. PMID: 22242847.
      View in: PubMed
    2. Jefford CW. New developments in synthetic peroxidic drugs as artemisinin mimics. Drug Discov Today. 2007 Jun; 12(11-12):487-95. PMID: 17532534.
      View in: PubMed
    3. Tripathi R, Jefford CW, Dutta GP. Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo. Parasitology. 2006 Jul; 133(Pt 1):1-9. PMID: 16764736.
      View in: PubMed
    4. Nogita R, Matohara K, Yamaji M, Oda T, Sakamoto Y, Kumagai T, Lim C, Yasutake M, Shimo T, Jefford CW, Shinmyozu T. Photochemical study of [3(3)](1,3,5)cyclophane and emission spectral properties of [3n]cyclophanes (n = 2-6). J Am Chem Soc. 2004 Oct 27; 126(42):13732-41. PMID: 15493932.
      View in: PubMed
    5. Jefford CW. Synthetic peroxides as antimalarials. Curr Opin Investig Drugs. 2004 Aug; 5(8):866-72. PMID: 15600243.
      View in: PubMed
    6. Jefford CW, Rossier JC, Boukouvalas J, Sledeski AW, Huang PZ. A concise synthesis of siphonodictidine. J Nat Prod. 2004 Aug; 67(8):1383-6. PMID: 15332858.
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    7. Peters W, Fleck SL, Robinson BL, Stewart LB, Jefford CW. The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials. Ann Trop Med Parasitol. 2002 Sep; 96(6):559-73. PMID: 12396319.
      View in: PubMed
    8. Jefford CW. Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action. Curr Med Chem. 2001 Dec; 8(15):1803-26. PMID: 11772352.
      View in: PubMed
    9. Kuniyoshi M, Marma MS, Higa T, Bernardinelli G, Jefford CW. New bromoterpenes from the red alga Laurencia luzonensis. J Nat Prod. 2001 Jun; 64(6):696-700. PMID: 11421726.
      View in: PubMed
    10. Jefford CW, Grigorov M, Weber J, Lüthi HP, Tronchet JM. Correlating the molecular electrostatic potentials of some organic peroxides with their antimalarial activities. J Chem Inf Comput Sci. 2000 Mar-Apr; 40(2):354-7. PMID: 10761139.
      View in: PubMed
    11. Grigorov M, Weber J, Tronchet JM, Jefford CW, Milhous WK, Maric D. A QSAR study of the antimalarial activity of some synthetic 1,2,4-trioxanes. J Chem Inf Comput Sci. 1997 Jan-Feb; 37(1):124-30. PMID: 9025258.
      View in: PubMed
    12. Meshnick SR, Jefford CW, Posner GH, Avery MA, Peters W. Second-generation antimalarial endoperoxides. Parasitol Today. 1996 Feb; 12(2):79-82. PMID: 15275260.
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    13. Peters W, Robinson BL, Tovey G, Rossier JC, Jefford CW. The chemotherapy of rodent malaria. L. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 3: Observations on 'Fenozan-50F', a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane. Ann Trop Med Parasitol. 1993 Apr; 87(2):111-23. PMID: 8561518.
      View in: PubMed
    14. Peters W, Robinson BL, Rossier JC, Misra D, Jefford CW, Rossiter JC. The chemotherapy of rodent malaria. XLIX. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 2: Structure-activity studies on cis-fused cyclopenteno-1,2,4-trioxanes (fenozans) against drug-sensitive and drug-resistant lines of Plasmodium berghei and P. yoelii ssp. NS in vivo. Ann Trop Med Parasitol. 1993 Feb; 87(1):9-16. PMID: 8346994.
      View in: PubMed
    15. Peters W, Robinson BL, Rossier JC, Jefford CW. The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives. Ann Trop Med Parasitol. 1993 Feb; 87(1):1-7. PMID: 8346987.
      View in: PubMed
    16. Jefford CW, Boschung AF, Bolsman TA, Moriatry RM, Melnick B. Reaction of singlet oxygen with alpha-ketocarboxylic acids. Oxidative decarboxylation and peroxyacid formation. J Am Chem Soc. 1976 Feb 18; 98(4):1017-8. PMID: 1245700.
      View in: PubMed
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