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Professor Roberto Docampo

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chiurillo MA, Lander N, Bertolini MS, Storey M, Vercesi AE, Docampo R. Different Roles of Mitochondrial Calcium Uniporter Complex Subunits in Growth and Infectivity of Trypanosoma cruzi. MBio. 2017 May 09; 8(3). PMID: 28487431.
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    2. Galaka T, Ferrer Casal M, Storey M, Li C, Chao MN, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Antiparasitic Activity of Sulfur- and Fluorine-Containing Bisphosphonates against Trypanosomatids and Apicomplexan Parasites. Molecules. 2017 Jan 04; 22(1). PMID: 28054995.
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    3. Lander N, Chiurillo MA, Storey M, Vercesi AE, Docampo R. CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor. J Biol Chem. 2016 Dec 02; 291(49):25505-25515. PMID: 27793988.
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    4. Lander N, Li ZH, Niyogi S, Docampo R. CRISPR/Cas9-Induced Disruption of Paraflagellar Rod Protein 1 and 2 Genes in Trypanosoma cruzi Reveals Their Role in Flagellar Attachment. MBio. 2015 Jul 21; 6(4):e01012. PMID: 26199333; PMCID: PMC4513075.
    5. Jimenez V, Docampo R. TcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism in Trypanosoma cruzi. Mol Microbiol. 2015 Sep; 97(5):911-25. PMID: 26031800; PMCID: PMC4632986.
    6. Niyogi S, Jimenez V, Girard-Dias W, de Souza W, Miranda K, Docampo R. Rab32 is essential for maintaining functional acidocalcisomes, and for growth and infectivity of Trypanosoma cruzi. J Cell Sci. 2015 Jun 15; 128(12):2363-73. PMID: 25964650; PMCID: PMC4487017.
    7. Huang G, Docampo R. Proteomic analysis of acidocalcisomes of Trypanosoma brucei uncovers their role in phosphate metabolism, cation homeostasis, and calcium signaling. Commun Integr Biol. 2015 Mar-Apr; 8(2):e1017174. PMID: 26480268; PMCID: PMC4594416.
    8. Chao MN, Matiuzzi CE, Storey M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii. ChemMedChem. 2015 Jun; 10(6):1094-108. PMID: 25914175; PMCID: PMC4447534.
    9. King-Keller S, Moore CA, Docampo R, Moreno SN. Ca2+ Regulation of Trypanosoma brucei Phosphoinositide Phospholipase C. Eukaryot Cell. 2015 May; 14(5):486-94. PMID: 25769297; PMCID: PMC4421009.
    10. Veiga-Santos P, Li K, Lameira L, de Carvalho TM, Huang G, Galizzi M, Shang N, Li Q, Gonzalez-Pacanowska D, Hernandez-Rodriguez V, Benaim G, Guo RT, Urbina JA, Docampo R, de Souza W, Oldfield E. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr; 59(4):1950-61. PMID: 25583723; PMCID: PMC4356821.
    11. Niyogi S, Docampo R. A novel role of Rab11 in trafficking GPI-anchored trans-sialidase to the plasma membrane of Trypanosoma cruzi. Small GTPases. 2015; 6(1):8-10. PMID: 25862161; PMCID: PMC4601394.
    12. Huang G, Ulrich PN, Storey M, Johnson D, Tischer J, Tovar JA, Moreno SN, Orlando R, Docampo R. Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells. PLoS Pathog. 2014 Dec; 10(12):e1004555. PMID: 25503798; PMCID: PMC4263762.
    13. Docampo R. Polyphosphate: a target for thrombosis attenuation. Blood. 2014 Nov 20; 124(22):3177-8. PMID: 25414432.
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    14. Docampo R, Huang G. Calcium signaling in trypanosomatid parasites. Cell Calcium. 2015 Mar; 57(3):194-202. PMID: 25468729; PMCID: PMC4355036.
    15. Docampo R, Vercesi AE, Huang G. Mitochondrial calcium transport in trypanosomes. Mol Biochem Parasitol. 2014 Sep; 196(2):108-16. PMID: 25218432; PMCID: PMC4253566.
    16. Niyogi S, Mucci J, Campetella O, Docampo R. Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruzi. PLoS Pathog. 2014 Jun; 10(6):e1004224. PMID: 24968013; PMCID: PMC4072791.
    17. Shang N, Li Q, Ko TP, Chan HC, Li J, Zheng Y, Huang CH, Ren F, Chen CC, Zhu Z, Galizzi M, Li ZH, Rodrigues-Poveda CA, Gonzalez-Pacanowska D, Veiga-Santos P, de Carvalho TM, de Souza W, Urbina JA, Wang AH, Docampo R, Li K, Liu YL, Oldfield E, Guo RT. Squalene synthase as a target for Chagas disease therapeutics. PLoS Pathog. 2014 May; 10(5):e1004114. PMID: 24789335; PMCID: PMC4006925.
    18. Porcel BM, Denoeud F, Opperdoes F, Noel B, Madoui MA, Hammarton TC, Field MC, Da Silva C, Couloux A, Poulain J, Katinka M, Jabbari K, Aury JM, Campbell DA, Cintron R, Dickens NJ, Docampo R, Sturm NR, Koumandou VL, Fabre S, Flegontov P, Lukeš J, Michaeli S, Mottram JC, Szöor B, Zilberstein D, Bringaud F, Wincker P, Dollet M. The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants. PLoS Genet. 2014 Feb; 10(2):e1004007. PMID: 24516393; PMCID: PMC3916237.
    19. Ulrich PN, Lander N, Kurup SP, Reiss L, Brewer J, Soares Medeiros LC, Miranda K, Docampo R. The acidocalcisome vacuolar transporter chaperone 4 catalyzes the synthesis of polyphosphate in insect-stages of Trypanosoma brucei and T. cruzi. J Eukaryot Microbiol. 2014 Mar-Apr; 61(2):155-65. PMID: 24386955; PMCID: PMC3959231.
    20. Docampo R. Letter from the editor. J Eukaryot Microbiol. 2014 Jan-Feb; 61(1):1. PMID: 24460698.
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    21. Docampo R, Moreno SN, Plattner H. Intracellular calcium channels in protozoa. Eur J Pharmacol. 2014 Sep 15; 739:4-18. PMID: 24291099; PMCID: PMC4037393.
    22. Ferrer-Casal M, Li C, Galizzi M, Stortz CA, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. New insights into molecular recognition of 1,1-bisphosphonic acids by farnesyl diphosphate synthase. Bioorg Med Chem. 2014 Jan 01; 22(1):398-405. PMID: 24300918; PMCID: PMC3902031.
    23. Lander N, Ulrich PN, Docampo R. Trypanosoma brucei vacuolar transporter chaperone 4 (TbVtc4) is an acidocalcisome polyphosphate kinase required for in vivo infection. J Biol Chem. 2013 Nov 22; 288(47):34205-16. PMID: 24114837; PMCID: PMC3837161.
    24. Galizzi M, Bustamante JM, Fang J, Miranda K, Soares Medeiros LC, Tarleton RL, Docampo R. Evidence for the role of vacuolar soluble pyrophosphatase and inorganic polyphosphate in Trypanosoma cruzi persistence. Mol Microbiol. 2013 Nov; 90(4):699-715. PMID: 24033456; PMCID: PMC3826824.
    25. Elicio PD, Chao MN, Galizzi M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents. Eur J Med Chem. 2013 Nov; 69:480-9. PMID: 24090919; PMCID: PMC3831659.
    26. Moreno SN, Docampo R. Polyphosphate and its diverse functions in host cells and pathogens. PLoS Pathog. 2013; 9(5):e1003230. PMID: 23658515; PMCID: PMC3642070.
    27. Huang G, Bartlett PJ, Thomas AP, Moreno SN, Docampo R. Acidocalcisomes of Trypanosoma brucei have an inositol 1,4,5-trisphosphate receptor that is required for growth and infectivity. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1887-92. PMID: 23319604; PMCID: PMC3562765.
    28. Docampo R. Redesign of the articles that now have a more modern look. J Eukaryot Microbiol. 2013 Jan-Feb; 60(1):1. PMID: 23289637.
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    29. Docampo R, Jimenez V, Lander N, Li ZH, Niyogi S. New insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protists. Int Rev Cell Mol Biol. 2013; 305:69-113. PMID: 23890380; PMCID: PMC3818246.
    30. Huang G, Vercesi AE, Docampo R. Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter. Nat Commun. 2013; 4:2865. PMID: 24305511; PMCID: PMC3868461.
    31. Recher M, Barboza AP, Li ZH, Galizzi M, Ferrer-Casal M, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB. Design, synthesis and biological evaluation of sulfur-containing 1,1-bisphosphonic acids as antiparasitic agents. Eur J Med Chem. 2013 Feb; 60:431-40. PMID: 23318904; PMCID: PMC3582829.
    32. Aripirala S, Szajnman SH, Jakoncic J, Rodriguez JB, Docampo R, Gabelli SB, Amzel LM. Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J Med Chem. 2012 Jul 26; 55(14):6445-54. PMID: 22715997; PMCID: PMC4710095.
    33. Moreno-Sanchez D, Hernandez-Ruiz L, Ruiz FA, Docampo R. Polyphosphate is a novel pro-inflammatory regulator of mast cells and is located in acidocalcisomes. J Biol Chem. 2012 Aug 17; 287(34):28435-44. PMID: 22761438; PMCID: PMC3436523.
    34. Jimenez V, Docampo R. Molecular and electrophysiological characterization of a novel cation channel of Trypanosoma cruzi. PLoS Pathog. 2012; 8(6):e1002750. PMID: 22685407; PMCID: PMC3369953.
    35. Li ZH, De Gaudenzi JG, Alvarez VE, Mendiondo N, Wang H, Kissinger JC, Frasch AC, Docampo R. A 43-nucleotide U-rich element in 3'-untranslated region of large number of Trypanosoma cruzi transcripts is important for mRNA abundance in intracellular amastigotes. J Biol Chem. 2012 Jun 01; 287(23):19058-69. PMID: 22500021; PMCID: PMC3365939.
    36. Long TE, Lu X, Galizzi M, Docampo R, Gut J, Rosenthal PJ. Phosphonium lipocations as antiparasitic agents. Bioorg Med Chem Lett. 2012 Apr 15; 22(8):2976-9. PMID: 22414614; PMCID: PMC3321104.
    37. Demoro B, Caruso F, Rossi M, Benítez D, González M, Cerecetto H, Galizzi M, Malayil L, Docampo R, Faccio R, Mombrú AW, Gambino D, Otero L. Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. Dalton Trans. 2012 Jun 07; 41(21):6468-76. PMID: 22344249.
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    38. Szajnman SH, Rosso VS, Malayil L, Smith A, Moreno SN, Docampo R, Rodriguez JB. 1-(Fluoroalkylidene)-1,1-bisphosphonic acids are potent and selective inhibitors of the enzymatic activity of Toxoplasma gondii farnesyl pyrophosphate synthase. Org Biomol Chem. 2012 Feb 21; 10(7):1424-33. PMID: 22215028; PMCID: PMC3458512.
    39. Docampo R, Lukeš J. Trypanosomes and the solution to a 50-year mitochondrial calcium mystery. Trends Parasitol. 2012 Jan; 28(1):31-7. PMID: 22088944; PMCID: PMC3246531.
    40. Ramos I, Gomes F, Koeller CM, Saito K, Heise N, Masuda H, Docampo R, de Souza W, Machado EA, Miranda K. Acidocalcisomes as calcium- and polyphosphate-storage compartments during embryogenesis of the insect Rhodnius prolixus Stahl. PLoS One. 2011; 6(11):e27276. PMID: 22096545; PMCID: PMC3214050.
    41. Li ZH, Alvarez VE, De Gaudenzi JG, Sant'Anna C, Frasch AC, Cazzulo JJ, Docampo R. Hyperosmotic stress induces aquaporin-dependent cell shrinkage, polyphosphate synthesis, amino acid accumulation, and global gene expression changes in Trypanosoma cruzi. J Biol Chem. 2011 Dec 23; 286(51):43959-71. PMID: 22039054; PMCID: PMC3243512.
    42. Huang G, Fang J, Sant'Anna C, Li ZH, Wellems DL, Rohloff P, Docampo R. Adaptor protein-3 (AP-3) complex mediates the biogenesis of acidocalcisomes and is essential for growth and virulence of Trypanosoma brucei. J Biol Chem. 2011 Oct 21; 286(42):36619-30. PMID: 21880705; PMCID: PMC3196089.
    43. Docampo R, Moreno SN. Acidocalcisomes. Cell Calcium. 2011 Aug; 50(2):113-9. PMID: 21752464; PMCID: PMC3156361.
    44. Soares Medeiros LC, Gomes F, Maciel LR, Seabra SH, Docampo R, Moreno S, Plattner H, Hentschel J, Kawazoe U, Barrabin H, de Souza W, Damatta RA, Miranda K. Volutin granules of Eimeria parasites are acidic compartments and have physiological and structural characteristics similar to acidocalcisomes. J Eukaryot Microbiol. 2011 Sep-Oct; 58(5):416-23. PMID: 21699625; PMCID: PMC3443593.
    45. Rosso VS, Szajnman SH, Malayil L, Galizzi M, Moreno SN, Docampo R, Rodriguez JB. Synthesis and biological evaluation of new 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem. 2011 Apr 01; 19(7):2211-7. PMID: 21419634; PMCID: PMC3071284.
    46. Ulrich PN, Jimenez V, Park M, Martins VP, Atwood J, Moles K, Collins D, Rohloff P, Tarleton R, Moreno SN, Orlando R, Docampo R. Identification of contractile vacuole proteins in Trypanosoma cruzi. PLoS One. 2011 Mar 18; 6(3):e18013. PMID: 21437209; PMCID: PMC3060929.
    47. De Lederkremer RM, Agusti R, Docampo R. Inositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids. J Eukaryot Microbiol. 2011 Mar-Apr; 58(2):79-87. PMID: 21332877; PMCID: PMC3444516.
    48. Docampo R. Molecular parasitology in the 21st century. Essays Biochem. 2011; 51:1-13. PMID: 22023438; PMCID: PMC3431016.
    49. Docampo R, Jimenez V, King-Keller S, Li ZH, Moreno SN. The role of acidocalcisomes in the stress response of Trypanosoma cruzi. Adv Parasitol. 2011; 75:307-24. PMID: 21820562; PMCID: PMC3427654.
    50. Schoijet AC, Miranda K, Medeiros LC, de Souza W, Flawiá MM, Torres HN, Pignataro OP, Docampo R, Alonso GD. Defining the role of a FYVE domain in the localization and activity of a cAMP phosphodiesterase implicated in osmoregulation in Trypanosoma cruzi. Mol Microbiol. 2011 Jan; 79(1):50-62. PMID: 21166893; PMCID: PMC3056490.
    51. Demoro B, Caruso F, Rossi M, Benítez D, Gonzalez M, Cerecetto H, Parajón-Costa B, Castiglioni J, Galizzi M, Docampo R, Otero L, Gambino D. Risedronate metal complexes potentially active against Chagas disease. J Inorg Biochem. 2010 Dec; 104(12):1252-8. PMID: 20817265; PMCID: PMC2949467.
    52. Ramos IB, Miranda K, Pace DA, Verbist KC, Lin FY, Zhang Y, Oldfield E, Machado EA, De Souza W, Docampo R. Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP. Biochem J. 2010 Aug 01; 429(3):485-95. PMID: 20497125; PMCID: PMC2907711.
    53. de Paulo Martins V, Okura M, Maric D, Engman DM, Vieira M, Docampo R, Moreno SN. Acylation-dependent export of Trypanosoma cruzi phosphoinositide-specific phospholipase C to the outer surface of amastigotes. J Biol Chem. 2010 Oct 01; 285(40):30906-17. PMID: 20647312; PMCID: PMC2945582.
    54. Martins Vde P, Galizzi M, Salto ML, Docampo R, Moreno SN. Developmental expression of a Trypanosoma cruzi phosphoinositide-specific phospholipase C in amastigotes and stimulation of host phosphoinositide hydrolysis. Infect Immun. 2010 Oct; 78(10):4206-12. PMID: 20643853; PMCID: PMC2950344.
    55. King-Keller S, Li M, Smith A, Zheng S, Kaur G, Yang X, Wang B, Docampo R. Chemical validation of phosphodiesterase C as a chemotherapeutic target in Trypanosoma cruzi, the etiological agent of Chagas' disease. Antimicrob Agents Chemother. 2010 Sep; 54(9):3738-45. PMID: 20625148; PMCID: PMC2934955.
    56. de Jesus TC, Tonelli RR, Nardelli SC, da Silva Augusto L, Motta MC, Girard-Dias W, Miranda K, Ulrich P, Jimenez V, Barquilla A, Navarro M, Docampo R, Schenkman S. Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei. J Biol Chem. 2010 Jul 30; 285(31):24131-40. PMID: 20495004; PMCID: PMC2911323.
    57. Singh AP, Zhang Y, No JH, Docampo R, Nussenzweig V, Oldfield E. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul; 54(7):2987-93. PMID: 20457823; PMCID: PMC2897311.
    58. Ramos IB, Miranda K, Ulrich P, Ingram P, LeFurgey A, Machado EA, de Souza W, Docampo R. Calcium- and polyphosphate-containing acidocalcisomes in chicken egg yolk. Biol Cell. 2010 Apr 09; 102(7):421-34. PMID: 20196772.
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    59. Patel S, Docampo R. Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling. Trends Cell Biol. 2010 May; 20(5):277-86. PMID: 20303271; PMCID: PMC2862797.
    60. Docampo R, Ulrich P, Moreno SN. Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbes. Philos Trans R Soc Lond B Biol Sci. 2010 Mar 12; 365(1541):775-84. PMID: 20124344; PMCID: PMC2817225.
    61. Patel S, Docampo R. In with the TRP channels: intracellular functions for TRPM1 and TRPM2. Sci Signal. 2009 Nov 03; 2(95):pe69. PMID: 19887679; PMCID: PMC2797805.
    62. Lander N, Bernal C, Diez N, Añez N, Docampo R, Ramírez JL. Localization and developmental regulation of a dispersed gene family 1 protein in Trypanosoma cruzi. Infect Immun. 2010 Jan; 78(1):231-40. PMID: 19841080; PMCID: PMC2798230.
    63. Moreno SN, Docampo R. The role of acidocalcisomes in parasitic protists. J Eukaryot Microbiol. 2009 May-Jun; 56(3):208-13. PMID: 19527347; PMCID: PMC2802266.
    64. Mezencev R, Galizzi M, Kutschy P, Docampo R. Trypanosoma cruzi: antiproliferative effect of indole phytoalexins on intracellular amastigotes in vitro. Exp Parasitol. 2009 May; 122(1):66-9. PMID: 19545522; PMCID: PMC2784243.
    65. Motta LS, Ramos IB, Gomes FM, de Souza W, Champagne DE, Santiago MF, Docampo R, Miranda K, Machado EA. Proton-pyrophosphatase and polyphosphate in acidocalcisome-like vesicles from oocytes and eggs of Periplaneta americana. Insect Biochem Mol Biol. 2009 Mar; 39(3):198-206. PMID: 19111615.
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    66. Schoijet AC, Miranda K, Girard-Dias W, de Souza W, Flawiá MM, Torres HN, Docampo R, Alonso GD. A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis. J Biol Chem. 2008 Nov 14; 283(46):31541-50. PMID: 18801733; PMCID: PMC2581564.
    67. Ferella M, Nilsson D, Darban H, Rodrigues C, Bontempi EJ, Docampo R, Andersson B. Proteomics in Trypanosoma cruzi--localization of novel proteins to various organelles. Proteomics. 2008 Jul; 8(13):2735-49. PMID: 18546153; PMCID: PMC2706665.
    68. Ferella M, Li ZH, Andersson B, Docampo R. Farnesyl diphosphate synthase localizes to the cytoplasm of Trypanosoma cruzi and T. brucei. Exp Parasitol. 2008 Jun; 119(2):308-12. PMID: 18406406; PMCID: PMC2409970.
    69. Docampo R, Moreno SN. The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites. Curr Pharm Des. 2008; 14(9):882-8. PMID: 18473837; PMCID: PMC2664259.
    70. Docampo R. Special section on novel organelles in parasitic protozoa. Exp Parasitol. 2008 Jan; 118(1):1. PMID: 18164906.
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    71. Szajnman SH, García Liñares GE, Li ZH, Jiang C, Galizzi M, Bontempi EJ, Ferella M, Moreno SN, Docampo R, Rodriguez JB. Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem. 2008 Mar 15; 16(6):3283-90. PMID: 18096393; PMCID: PMC2330165.
    72. Salto ML, Kuhlenschmidt T, Kuhlenschmidt M, de Lederkremer RM, Docampo R. Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi. Mol Biochem Parasitol. 2008 Apr; 158(2):120-30. PMID: 18207579; PMCID: PMC2413051.
    73. Fang J, Rohloff P, Miranda K, Docampo R. Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect. Biochem J. 2007 Oct 15; 407(2):161-70. PMID: 17635107; PMCID: PMC2049025.
    74. Fang J, Ruiz FA, Docampo M, Luo S, Rodrigues JC, Motta LS, Rohloff P, Docampo R. Overexpression of a Zn2+-sensitive soluble exopolyphosphatase from Trypanosoma cruzi depletes polyphosphate and affects osmoregulation. J Biol Chem. 2007 Nov 02; 282(44):32501-10. PMID: 17827150.
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    75. Liñares GG, Gismondi S, Codesido NO, Moreno SN, Docampo R, Rodriguez JB. Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation. Bioorg Med Chem Lett. 2007 Sep 15; 17(18):5068-71. PMID: 17643987; PMCID: PMC2707766.
    76. Rohloff P, Docampo R. A contractile vacuole complex is involved in osmoregulation in Trypanosoma cruzi. Exp Parasitol. 2008 Jan; 118(1):17-24. PMID: 17574552; PMCID: PMC2243178.
    77. Ferella M, Montalvetti A, Rohloff P, Miranda K, Fang J, Reina S, Kawamukai M, Búa J, Nilsson D, Pravia C, Katzin A, Cassera MB, Aslund L, Andersson B, Docampo R, Bontempi EJ. A solanesyl-diphosphate synthase localizes in glycosomes of Trypanosoma cruzi. J Biol Chem. 2006 Dec 22; 281(51):39339-48. PMID: 17062572.
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    78. Rohloff P, Docampo R. Ammonium production during hypo-osmotic stress leads to alkalinization of acidocalcisomes and cytosolic acidification in Trypanosoma cruzi. Mol Biochem Parasitol. 2006 Dec; 150(2):249-55. PMID: 17005261.
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    79. Luo S, Fang J, Docampo R. Molecular characterization of Trypanosoma brucei P-type H+-ATPases. J Biol Chem. 2006 Aug 04; 281(31):21963-73. PMID: 16757482.
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    80. Ravaschino EL, Docampo R, Rodriguez JB. Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis. J Med Chem. 2006 Jan 12; 49(1):426-35. PMID: 16392828.
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    81. Smith SA, Mutch NJ, Baskar D, Rohloff P, Docampo R, Morrissey JH. Polyphosphate modulates blood coagulation and fibrinolysis. Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):903-8. PMID: 16410357; PMCID: PMC1347979.
    82. Gabelli SB, McLellan JS, Montalvetti A, Oldfield E, Docampo R, Amzel LM. Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design. Proteins. 2006 Jan 01; 62(1):80-8. PMID: 16288456.
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    83. Vieira M, Rohloff P, Luo S, Cunha-e-Silva NL, de Souza W, Docampo R. Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi. Biochem J. 2005 Dec 15; 392(Pt 3):467-74. PMID: 16149915; PMCID: PMC1316285.
    84. Szajnman SH, Ravaschino EL, Docampo R, Rodriguez JB. Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase. Bioorg Med Chem Lett. 2005 Nov 01; 15(21):4685-90. PMID: 16143525.
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    85. Kotsikorou E, Song Y, Chan JM, Faelens S, Tovian Z, Broderick E, Bakalara N, Docampo R, Oldfield E. Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase. J Med Chem. 2005 Sep 22; 48(19):6128-39. PMID: 16162013.
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    86. Cuevas IC, Rohloff P, Sánchez DO, Docampo R. Characterization of farnesylated protein tyrosine phosphatase TcPRL-1 from Trypanosoma cruzi. Eukaryot Cell. 2005 Sep; 4(9):1550-61. PMID: 16151248; PMCID: PMC1214199.
    87. Marchesini N, Vieira M, Luo S, Moreno SN, Docampo R. A malaria parasite-encoded vacuolar H(+)-ATPase is targeted to the host erythrocyte. J Biol Chem. 2005 Nov 04; 280(44):36841-7. PMID: 16135514.
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    88. Docampo R, de Souza W, Miranda K, Rohloff P, Moreno SN. Acidocalcisomes - conserved from bacteria to man. Nat Rev Microbiol. 2005 Mar; 3(3):251-61. PMID: 15738951.
      View in: PubMed
    89. Zhang K, Hsu FF, Scott DA, Docampo R, Turk J, Beverley SM. Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. Mol Microbiol. 2005 Mar; 55(5):1566-78. PMID: 15720561; PMCID: PMC3803142.
    90. Okura M, Fang J, Salto ML, Singer RS, Docampo R, Moreno SN. A lipid-modified phosphoinositide-specific phospholipase C (TcPI-PLC) is involved in differentiation of trypomastigotes to amastigotes of Trypanosoma cruzi. J Biol Chem. 2005 Apr 22; 280(16):16235-43. PMID: 15710612.
      View in: PubMed
    91. Miranda K, Vercesi AE, Catisti R, De Souza W, Rodrigues CO, Docampo R. P-type proton ATPases are involved in intracellular calcium and proton uptake in the plant parasite Phytomonas francai. J Eukaryot Microbiol. 2005 Jan-Feb; 52(1):55-60. PMID: 15702981.
      View in: PubMed
    92. Miranda K, Docampo R, Grillo O, de Souza W. Acidocalcisomes of trypanosomatids have species-specific elemental composition. Protist. 2004 Dec; 155(4):395-405. PMID: 15648720.
      View in: PubMed
    93. Rohloff P, Montalvetti A, Docampo R. Acidocalcisomes and the contractile vacuole complex are involved in osmoregulation in Trypanosoma cruzi. J Biol Chem. 2004 Dec 10; 279(50):52270-81. PMID: 15466463.
      View in: PubMed
    94. Docampo R. Introduction: A special issue on cellular biology of protozoan parasites. Microsc Microanal. 2004 Oct; 10(5):511-2. PMID: 15525426.
      View in: PubMed
    95. Ruiz FA, Luo S, Moreno SN, Docampo R. Polyphosphate content and fine structure of acidocalcisomes of Plasmodium falciparum. Microsc Microanal. 2004 Oct; 10(5):563-7. PMID: 15525430.
      View in: PubMed
    96. Miranda K, Rodrigues CO, Hentchel J, Vercesi A, Plattner H, de Souza W, Docampo R. Acidocalcisomes of Phytomonas françai possess distinct morphological characteristics and contain iron. Microsc Microanal. 2004 Oct; 10(5):647-55. PMID: 15525437.
      View in: PubMed
    97. Mao J, Gao YG, Odeh S, Robinson H, Montalvetti A, Docampo R, Oldfield E. Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase from Trypanosoma brucei. Acta Crystallogr D Biol Crystallogr. 2004 Oct; 60(Pt 10):1863-6. PMID: 15388934.
      View in: PubMed
    98. Seufferheld M, Lea CR, Vieira M, Oldfield E, Docampo R. The H(+)-pyrophosphatase of Rhodospirillum rubrum is predominantly located in polyphosphate-rich acidocalcisomes. J Biol Chem. 2004 Dec 03; 279(49):51193-202. PMID: 15371423.
      View in: PubMed
    99. Ruiz FA, Lea CR, Oldfield E, Docampo R. Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes. J Biol Chem. 2004 Oct 22; 279(43):44250-7. PMID: 15308650.
      View in: PubMed
    100. Montalvetti A, Rohloff P, Docampo R. A functional aquaporin co-localizes with the vacuolar proton pyrophosphatase to acidocalcisomes and the contractile vacuole complex of Trypanosoma cruzi. J Biol Chem. 2004 Sep 10; 279(37):38673-82. PMID: 15252016.
      View in: PubMed
    101. Miranda K, Docampo R, Grillo O, Franzen A, Attias M, Vercesi A, Plattner H, Hentschel J, de Souza W. Dynamics of polymorphism of acidocalcisomes in Leishmania parasites. Histochem Cell Biol. 2004 May; 121(5):407-18. PMID: 15138840.
      View in: PubMed
    102. Garzoni LR, Waghabi MC, Baptista MM, de Castro SL, Meirelles Mde N, Britto CC, Docampo R, Oldfield E, Urbina JA. Antiparasitic activity of risedronate in a murine model of acute Chagas' disease. Int J Antimicrob Agents. 2004 Mar; 23(3):286-90. PMID: 15164970.
      View in: PubMed
    103. Garzoni LR, Caldera A, Meirelles Mde N, de Castro SL, Docampo R, Meints GA, Oldfield E, Urbina JA. Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi. Int J Antimicrob Agents. 2004 Mar; 23(3):273-85. PMID: 15164969.
      View in: PubMed
    104. Luo S, Rohloff P, Cox J, Uyemura SA, Docampo R. Trypanosoma brucei plasma membrane-type Ca(2+)-ATPase 1 (TbPMC1) and 2 (TbPMC2) genes encode functional Ca(2+)-ATPases localized to the acidocalcisomes and plasma membrane, and essential for Ca(2+) homeostasis and growth. J Biol Chem. 2004 Apr 02; 279(14):14427-39. PMID: 14724285.
      View in: PubMed
    105. Lemercier G, Espiau B, Ruiz FA, Vieira M, Luo S, Baltz T, Docampo R, Bakalara N. A pyrophosphatase regulating polyphosphate metabolism in acidocalcisomes is essential for Trypanosoma brucei virulence in mice. J Biol Chem. 2004 Jan 30; 279(5):3420-5. PMID: 14615483.
      View in: PubMed
    106. Urbina JA, Docampo R. Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol. 2003 Nov; 19(11):495-501. PMID: 14580960.
      View in: PubMed
    107. Uyemura SA, Luo S, Vieira M, Moreno SN, Docampo R. Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii yoelii mitochondria in situ. J Biol Chem. 2004 Jan 02; 279(1):385-93. PMID: 14561763.
      View in: PubMed
    108. Szajnman SH, Montalvetti A, Wang Y, Docampo R, Rodriguez JB. Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. Bioorg Med Chem Lett. 2003 Oct 06; 13(19):3231-5. PMID: 12951099.
      View in: PubMed
    109. Docampo R. New and reemerging infectious diseases. Emerg Infect Dis. 2003 Aug; 9(8):1030-3. PMID: 12974240; PMCID: PMC3020621.
    110. Moreno SN, Docampo R. Calcium regulation in protozoan parasites. Curr Opin Microbiol. 2003 Aug; 6(4):359-64. PMID: 12941405.
      View in: PubMed
    111. Salto ML, Bertello LE, Vieira M, Docampo R, Moreno SN, de Lederkremer RM. Formation and remodeling of inositolphosphoceramide during differentiation of Trypanosoma cruzi from trypomastigote to amastigote. Eukaryot Cell. 2003 Aug; 2(4):756-68. PMID: 12912895; PMCID: PMC178363.
    112. Conte I, Labriola C, Cazzulo JJ, Docampo R, Parodi AJ. The interplay between folding-facilitating mechanisms in Trypanosoma cruzi endoplasmic reticulum. Mol Biol Cell. 2003 Sep; 14(9):3529-40. PMID: 12972544; PMCID: PMC196547.
    113. Seufferheld M, Vieira MC, Ruiz FA, Rodrigues CO, Moreno SN, Docampo R. Identification of organelles in bacteria similar to acidocalcisomes of unicellular eukaryotes. J Biol Chem. 2003 Aug 08; 278(32):29971-8. PMID: 12783865.
      View in: PubMed
    114. Urbina JA, Concepcion JL, Montalvetti A, Rodriguez JB, Docampo R. Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease. Antimicrob Agents Chemother. 2003 Jun; 47(6):2047-50. PMID: 12760897; PMCID: PMC155860.
    115. Montalvetti A, Fernandez A, Sanders JM, Ghosh S, Van Brussel E, Oldfield E, Docampo R. Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies. J Biol Chem. 2003 May 09; 278(19):17075-83. PMID: 12618430.
      View in: PubMed
    116. Rohloff P, Rodrigues CO, Docampo R. Regulatory volume decrease in Trypanosoma cruzi involves amino acid efflux and changes in intracellular calcium. Mol Biochem Parasitol. 2003 Feb; 126(2):219-30. PMID: 12615321.
      View in: PubMed
    117. Docampo R, Moreno SN. Current chemotherapy of human African trypanosomiasis. Parasitol Res. 2003 Jun; 90 Supp 1:S10-3. PMID: 12811544.
      View in: PubMed
    118. Rodrigues CO, Ruiz FA, Vieira M, Hill JE, Docampo R. An acidocalcisomal exopolyphosphatase from Leishmania major with high affinity for short chain polyphosphate. J Biol Chem. 2002 Dec 27; 277(52):50899-906. PMID: 12393865.
      View in: PubMed
    119. Luo S, Scott DA, Docampo R. Trypanosoma cruzi H+-ATPase 1 (TcHA1) and 2 (TcHA2) genes complement yeast mutants defective in H+ pumps and encode plasma membrane P-type H+-ATPases with different enzymatic properties. J Biol Chem. 2002 Nov 15; 277(46):44497-506. PMID: 12221074.
      View in: PubMed
    120. Docampo R. Fifth annual conference on new and re-emerging infectious diseases. Emerg Infect Dis. 2002 Sep; 8(9):1008-10. PMID: 12219739; PMCID: PMC2732540.
    121. Van der Heyden N, Docampo R. Significant differences between procyclic and bloodstream forms of Trypanosoma brucei in the maintenance of their plasma membrane potential. J Eukaryot Microbiol. 2002 Sep-Oct; 49(5):407-13. PMID: 12425529.
      View in: PubMed
    122. Elhalem E, Bailey BN, Docampo R, Ujváry I, Szajnman SH, Rodriguez JB. Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi. J Med Chem. 2002 Aug 29; 45(18):3984-99. PMID: 12190320.
      View in: PubMed
    123. Docampo R. New and re-emerging infectious diseases. Trends Parasitol. 2002 Aug; 18(8):334-6. PMID: 12377274.
      View in: PubMed
    124. Moreno B, Rodrigues CO, Bailey BN, Urbina JA, Moreno SN, Docampo R, Oldfield E. Magic-angle spinning (31)P NMR spectroscopy of condensed phosphates in parasitic protozoa: visualizing the invisible. FEBS Lett. 2002 Jul 17; 523(1-3):207-12. PMID: 12123833.
      View in: PubMed
    125. Lemercier G, Dutoya S, Luo S, Ruiz FA, Rodrigues CO, Baltz T, Docampo R, Bakalara N. A vacuolar-type H+-pyrophosphatase governs maintenance of functional acidocalcisomes and growth of the insect and mammalian forms of Trypanosoma brucei. J Biol Chem. 2002 Oct 04; 277(40):37369-76. PMID: 12121996.
      View in: PubMed
    126. Rodriguez N, Bailey BN, Martin MB, Oldfield E, Urbina JA, Docampo R. Radical cure of experimental cutaneous leishmaniasis by the bisphosphonate pamidronate. J Infect Dis. 2002 Jul 01; 186(1):138-40. PMID: 12089677.
      View in: PubMed
    127. Martinez R, Wang Y, Benaim G, Benchimol M, de Souza W, Scott DA, Docampo R. A proton pumping pyrophosphatase in the Golgi apparatus and plasma membrane vesicles of Trypanosoma cruzi. Mol Biochem Parasitol. 2002 Apr 09; 120(2):205-13. PMID: 11897126.
      View in: PubMed
    128. Yardley V, Khan AA, Martin MB, Slifer TR, Araujo FG, Moreno SN, Docampo R, Croft SL, Oldfield E. In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrob Agents Chemother. 2002 Mar; 46(3):929-31. PMID: 11850291; PMCID: PMC127510.
    129. Van Der Heyden N, Docampo R. Proton and sodium pumps regulate the plasma membrane potential of different stages of Trypanosoma cruzi. Mol Biochem Parasitol. 2002 Mar; 120(1):127-39. PMID: 11849712.
      View in: PubMed
    130. Rodriguez NM, Docampo R, Lu Hg HG, Scott DA. Overexpression of the Leishmania amazonensis Ca2+-ATPase gene lmaa1 enhances virulence. Cell Microbiol. 2002 Feb; 4(2):117-26. PMID: 11896767.
      View in: PubMed
    131. Marchesini N, Docampo R. A plasma membrane P-type H(+)-ATPase regulates intracellular pH in Leishmania mexicana amazonensis. Mol Biochem Parasitol. 2002 Feb; 119(2):225-36. PMID: 11814574.
      View in: PubMed
    132. Salto ML, Furuya T, Moreno SN, Docampo R, de Lederkremer RM. The phosphatidylinositol-phospholipase C from Trypanosoma cruzi is active on inositolphosphoceramide. Mol Biochem Parasitol. 2002 Jan; 119(1):131-3. PMID: 11755195.
      View in: PubMed
    133. Marchesini N, Ruiz FA, Vieira M, Docampo R. Acidocalcisomes are functionally linked to the contractile vacuole of Dictyostelium discoideum. J Biol Chem. 2002 Mar 08; 277(10):8146-53. PMID: 11748243.
      View in: PubMed
    134. Ruiz FA, Marchesini N, Seufferheld M. The polyphosphate bodies of Chlamydomonas reinhardtii possess a proton-pumping pyrophosphatase and are similar to acidocalcisomes. J Biol Chem. 2001 Dec 07; 276(49):46196-203. PMID: 11579086.
      View in: PubMed
    135. Rodrigues CO, Catisti R, Uyemura SA, Vercesi AE, Lira R, Rodriguez C, Urbina JA, Docampo R. The sterol composition of Trypanosoma cruzi changes after growth in different culture media and results in different sensitivity to digitonin-permeabilization. J Eukaryot Microbiol. 2001 Sep-Oct; 48(5):588-94. PMID: 11596924.
      View in: PubMed
    136. Docampo R. Recent developments in the chemotherapy of Chagas disease. Curr Pharm Des. 2001 Aug; 7(12):1157-64. PMID: 11472259.
      View in: PubMed
    137. Montalvetti A, Bailey BN, Martin MB, Severin GW, Oldfield E, Docampo R. Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. J Biol Chem. 2001 Sep 07; 276(36):33930-7. PMID: 11435429.
      View in: PubMed
    138. Moreno B, Bailey BN, Luo S, Martin MB, Kuhlenschmidt M, Moreno SN, Docampo R, Oldfield E. (31)P NMR of apicomplexans and the effects of risedronate on Cryptosporidium parvum growth. Biochem Biophys Res Commun. 2001 Jun 15; 284(3):632-7. PMID: 11396947.
      View in: PubMed
    139. Furuya T, Okura M, Ruiz FA, Scott DA, Docampo R. TcSCA complements yeast mutants defective in Ca2+ pumps and encodes a Ca2+-ATPase that localizes to the endoplasmic reticulum of Trypanosoma cruzi. J Biol Chem. 2001 Aug 31; 276(35):32437-45. PMID: 11382780.
      View in: PubMed
    140. Ruiz FA, Rodrigues CO, Docampo R. Rapid changes in polyphosphate content within acidocalcisomes in response to cell growth, differentiation, and environmental stress in Trypanosoma cruzi. J Biol Chem. 2001 Jul 13; 276(28):26114-21. PMID: 11371561.
      View in: PubMed
    141. Docampo R, Moreno SN. The acidocalcisome. Mol Biochem Parasitol. 2001 May; 114(2):151-9. PMID: 11378195.
      View in: PubMed
    142. Docampo R, Moreno SN. Bisphosphonates as chemotherapeutic agents against trypanosomatid and apicomplexan parasites. Curr Drug Targets Infect Disord. 2001 May; 1(1):51-61. PMID: 12455233.
      View in: PubMed
    143. Szajnman SH, Bailey BN, Docampo R, Rodriguez JB. Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi. Bioorg Med Chem Lett. 2001 Mar 26; 11(6):789-92. PMID: 11277521.
      View in: PubMed
    144. Martin MB, Grimley JS, Lewis JC, Heath HT, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SN, Docampo R, Croft SL, Oldfield E. Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. J Med Chem. 2001 Mar 15; 44(6):909-16. PMID: 11300872.
      View in: PubMed
    145. Hill JE, Scott DA, Luo S, Docampo R. Cloning and functional expression of a gene encoding a vacuolar-type proton-translocating pyrophosphatase from Trypanosoma cruzi. Biochem J. 2000 Oct 01; 351(Pt 1):281-8. PMID: 10998372; PMCID: PMC1221360.
    146. Moreno B, Urbina JA, Oldfield E, Bailey BN, Rodrigues CO, Docampo R. 31P NMR spectroscopy of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major. Evidence for high levels of condensed inorganic phosphates. J Biol Chem. 2000 Sep 15; 275(37):28356-62. PMID: 10871617.
      View in: PubMed
    147. Scott DA, Docampo R. Characterization of isolated acidocalcisomes of Trypanosoma cruzi. J Biol Chem. 2000 Aug 04; 275(31):24215-21. PMID: 10816577.
      View in: PubMed
    148. Docampo R. New and re-emerging diseases: a dedication to Norman D. Levine. Parasitol Today. 2000 Aug; 16(8):316-7. PMID: 10900471.
      View in: PubMed
    149. Vercesi AE, Rodrigues CO, Catisti R, Docampo R. Presence of a Na(+)/H(+) exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs. FEBS Lett. 2000 May 12; 473(2):203-6. PMID: 10812075.
      View in: PubMed
    150. Szajnman SH, Yan W, Bailey BN, Docampo R, Elhalem E, Rodriguez JB. Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation. J Med Chem. 2000 May 04; 43(9):1826-40. PMID: 10794699.
      View in: PubMed
    151. Miranda K, Benchimol M, Docampo R, de Souza W. The fine structure of acidocalcisomes in Trypanosoma cruzi. Parasitol Res. 2000 May; 86(5):373-84. PMID: 10836511.
      View in: PubMed
    152. Marchesini N, Luo S, Rodrigues CO, Moreno SN, Docampo R. Acidocalcisomes and a vacuolar H+-pyrophosphatase in malaria parasites. Biochem J. 2000 Apr 01; 347 Pt 1:243-53. PMID: 10727425; PMCID: PMC1220954.
    153. Uyemura SA, Luo S, Moreno SN, Docampo R. Oxidative phosphorylation, Ca(2+) transport, and fatty acid-induced uncoupling in malaria parasites mitochondria. J Biol Chem. 2000 Mar 31; 275(13):9709-15. PMID: 10734123.
      View in: PubMed
    154. Furuya T, Kashuba C, Docampo R, Moreno SN. A novel phosphatidylinositol-phospholipase C of Trypanosoma cruzi that is lipid modified and activated during trypomastigote to amastigote differentiation. J Biol Chem. 2000 Mar 03; 275(9):6428-38. PMID: 10692446.
      View in: PubMed
    155. VanderHeyden N, McLaughlin GL, Docampo R. Regulation of the plasma membrane potential in Pneumocystis carinii. FEMS Microbiol Lett. 2000 Feb 15; 183(2):327-30. PMID: 10675605.
      View in: PubMed
    156. Vanderheyden N, Wong J, Docampo R. A pyruvate-proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycle. Biochem J. 2000 Feb 15; 346 Pt 1:53-62. PMID: 10657239; PMCID: PMC1220822.
    157. Van Der Heyden N, Docampo R. Intracellular pH in mammalian stages of Trypanosoma cruzi is K+-dependent and regulated by H+-ATPases. Mol Biochem Parasitol. 2000 Feb 05; 105(2):237-51. PMID: 10693746.
      View in: PubMed
    158. Catisti R, Uyemura SA, Docampo R, Vercesi AE. Calcium mobilization by arachidonic acid in trypanosomatids. Mol Biochem Parasitol. 2000 Feb 05; 105(2):261-71. PMID: 10693748.
      View in: PubMed
    159. Rodriguez JB, Docampo R, Gros EG. Sulphur-containing derivatives structurally related to fenoxycarb are potent growth inhibitors against the intracellular form of Trypanosoma cruzi. Int J Antimicrob Agents. 2000 Jan; 13(3):215-8. PMID: 10724027.
      View in: PubMed
    160. Urbina JA, Moreno B, Vierkotter S, Oldfield E, Payares G, Sanoja C, Bailey BN, Yan W, Scott DA, Moreno SN, Docampo R. Trypanosoma cruzi contains major pyrophosphate stores, and its growth in vitro and in vivo is blocked by pyrophosphate analogs. J Biol Chem. 1999 Nov 19; 274(47):33609-15. PMID: 10559249.
      View in: PubMed
    161. Rodrigues CO, Scott DA, Docampo R. Characterization of a vacuolar pyrophosphatase in Trypanosoma brucei and its localization to acidocalcisomes. Mol Cell Biol. 1999 Nov; 19(11):7712-23. PMID: 10523660; PMCID: PMC84816.
    162. Docampo R, Moreno SN. Acidocalcisome: A novel Ca2+ storage compartment in trypanosomatids and apicomplexan parasites. Parasitol Today. 1999 Nov; 15(11):443-8. PMID: 10511686.
      View in: PubMed
    163. Luo S, Marchesini N, Moreno SN, Docampo R. A plant-like vacuolar H(+)-pyrophosphatase in Plasmodium falciparum. FEBS Lett. 1999 Oct 29; 460(2):217-20. PMID: 10544238.
      View in: PubMed
    164. Rodrigues CO, Scott DA, Docampo R. Presence of a vacuolar H+-pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H+-ATPase. Biochem J. 1999 Jun 15; 340 ( Pt 3):759-66. PMID: 10359662; PMCID: PMC1220309.
    165. Turrens JF, Newton CL, Zhong L, Hernandez FR, Whitfield J, Docampo R. Mercaptopyridine-N-oxide, an NADH-fumarate reductase inhibitor, blocks Trypanosoma cruzi growth in culture and in infected myoblasts. FEMS Microbiol Lett. 1999 Jun 15; 175(2):217-21. PMID: 10386371.
      View in: PubMed
    166. Rodriguez JB, Zhong L, Docampo R, Wimmer Z, Gros EG. Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi. Bioorg Med Chem Lett. 1998 Nov 17; 8(22):3257-60. PMID: 9873713.
      View in: PubMed
    167. Scott DA, de Souza W, Benchimol M, Zhong L, Lu HG, Moreno SN, Docampo R. Presence of a plant-like proton-pumping pyrophosphatase in acidocalcisomes of Trypanosoma cruzi. J Biol Chem. 1998 Aug 21; 273(34):22151-8. PMID: 9705361.
      View in: PubMed
    168. Benchimol M, De Souza W, Vanderheyden N, Zhong L, Lu HG, Moreno SN, Docampo R. Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi. Biochem J. 1998 Jun 15; 332 ( Pt 3):695-702. PMID: 9620872; PMCID: PMC1219530.
    169. Scott DA, Docampo R, Benchimol M. Analysis of the uptake of the fluorescent marker 2',7'-bis-(2-carboxyethyl)-5(and-6)-carboxyfluorescein (BCECF) by hydrogenosomes in Trichomonas vaginalis. Eur J Cell Biol. 1998 Jun; 76(2):139-45. PMID: 9696354.
      View in: PubMed
    170. Furuya T, Zhong L, Meyer-Fernandes JR, Lu HG, Moreno SN, Docampo R. Ecto-protein tyrosine phosphatase activity in Trypanosoma cruzi infective stages. Mol Biochem Parasitol. 1998 May 01; 92(2):339-48. PMID: 9657337.
      View in: PubMed
    171. Cinque GM, Szajnman SH, Zhong L, Docampo R, Schvartzapel AJ, Rodriguez JB, Gros EG. Structure-activity relationship of new growth inhibitors of Trypanosoma cruzi. J Med Chem. 1998 Apr 23; 41(9):1540-54. PMID: 9554887.
      View in: PubMed
    172. Scott DA, Docampo R. Two types of H+-ATPase are involved in the acidification of internal compartments in Trypanosoma cruzi. Biochem J. 1998 Apr 15; 331 ( Pt 2):583-9. PMID: 9531501; PMCID: PMC1219392.
    173. Zhong L, Lu HG, Moreno SN, Docampo R. Tyrosine phosphate hydrolysis of host proteins by Trypanosoma cruzi is linked to cell invasion. FEMS Microbiol Lett. 1998 Apr 01; 161(1):15-20. PMID: 9561728.
      View in: PubMed
    174. Lu HG, Zhong L, de Souza W, Benchimol M, Moreno S, Docampo R. Ca2+ content and expression of an acidocalcisomal calcium pump are elevated in intracellular forms of Trypanosoma cruzi. Mol Cell Biol. 1998 Apr; 18(4):2309-23. PMID: 9528801; PMCID: PMC121484.
    175. Vercesi AE, Grijalba MT, Docampo R. Inhibition of Ca2+ release from Trypanosoma brucei acidocalcisomes by 3,5-dibutyl-4-hydroxytoluene: role of the Na+/H+ exchanger. Biochem J. 1997 Dec 01; 328 ( Pt 2):479-82. PMID: 9371704; PMCID: PMC1218944.
    176. Scott DA, Docampo R, Dvorak JA, Shi S, Leapman RD. In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi. J Biol Chem. 1997 Oct 31; 272(44):28020-9. PMID: 9346954.
      View in: PubMed
    177. Schvartzapel AJ, Zhong L, Docampo R, Rodriguez JB, Gros EG. Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes). J Med Chem. 1997 Jul 18; 40(15):2314-22. PMID: 9240347.
      View in: PubMed
    178. Urbina JA, Visbal G, Contreras LM, McLaughlin G, Docampo R. Inhibitors of delta24(25) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii. Antimicrob Agents Chemother. 1997 Jul; 41(7):1428-32. PMID: 9210660; PMCID: PMC163934.
    179. Lu HG, Zhong L, Chang KP, Docampo R. Intracellular Ca2+ pool content and signaling and expression of a calcium pump are linked to virulence in Leishmania mexicana amazonesis amastigotes. J Biol Chem. 1997 Apr 04; 272(14):9464-73. PMID: 9083086.
      View in: PubMed
    180. Docampo R, Schmuñis GA. Sterol biosynthesis inhibitors: potential chemotherapeutics against Chagas disease. Parasitol Today. 1997 Apr; 13(4):129-30. PMID: 15275097.
      View in: PubMed
    181. Turrens JF, Watts BP, Zhong L, Docampo R. Inhibition of Trypanosoma cruzi and T. brucei NADH fumarate reductase by benznidazole and anthelmintic imidazole derivatives. Mol Biochem Parasitol. 1996 Nov 12; 82(1):125-9. PMID: 8943158.
      View in: PubMed
    182. Vanderheyden N, Benaim G, Docampo R. The role of a H(+)-ATPase in the regulation of cytoplasmic pH in Trypanosoma cruzi epimastigotes. Biochem J. 1996 Aug 15; 318 ( Pt 1):103-9. PMID: 8761458; PMCID: PMC1217594.
    183. Suju M, Davila M, Poleo G, Docampo R, Benaim G. Phosphatidylethanol stimulates the plasma-membrane calcium pump from human erythrocytes. Biochem J. 1996 Aug 01; 317 ( Pt 3):933-8. PMID: 8760385; PMCID: PMC1217575.
    184. Docampo R, Vanderheyden NM, Shaw MM, Durant PJ, Bartlett MS, Smith JW, McLaughlin GL. An H(+)-ATPase regulates cytoplasmic pH in Pneumocystis carinii trophozoites. Biochem J. 1996 Jun 01; 316 ( Pt 2):681-4. PMID: 8687417; PMCID: PMC1217401.
    185. Vercesi AE, Docampo R. Sodium-proton exchange stimulates Ca2+ release from acidocalcisomes of Trypanosoma brucei. Biochem J. 1996 Apr 01; 315 ( Pt 1):265-70. PMID: 8670117; PMCID: PMC1217181.
    186. Docampo R, Moreno SN. The role of Ca2+ in the process of cell invasion by intracellular parasites. Parasitol Today. 1996 Feb; 12(2):61-5. PMID: 15275256.
      View in: PubMed
    187. Scott DA, Moreno SN, Docampo R. Ca2+ storage in Trypanosoma brucei: the influence of cytoplasmic pH and importance of vacuolar acidity. Biochem J. 1995 Sep 15; 310 ( Pt 3):789-94. PMID: 7575411; PMCID: PMC1135967.
    188. Docampo R, Scott DA, Vercesi AE, Moreno SN. Intracellular Ca2+ storage in acidocalcisomes of Trypanosoma cruzi. Biochem J. 1995 Sep 15; 310 ( Pt 3):1005-12. PMID: 7575396; PMCID: PMC1135995.
    189. Hoffmann ME, Jang J, Moreno SN, Docampo R. Inhibition of protein synthesis and amino acid transport by crystal violet in Trypanosoma cruzi. J Eukaryot Microbiol. 1995 May-Jun; 42(3):293-7. PMID: 7496387.
      View in: PubMed
    190. Benaim G, Moreno SN, Hutchinson G, Cervino V, Hermoso T, Romero PJ, Ruiz F, de Souza W, Docampo R. Characterization of the plasma-membrane calcium pump from Trypanosoma cruzi. Biochem J. 1995 Feb 15; 306 ( Pt 1):299-303. PMID: 7532400; PMCID: PMC1136516.
    191. Vercesi AE, Moreno SN, Docampo R. Ca2+/H+ exchange in acidic vacuoles of Trypanosoma brucei. Biochem J. 1994 Nov 15; 304 ( Pt 1):227-33. PMID: 7998937; PMCID: PMC1137476.
    192. Moreno SN, Silva J, Vercesi AE, Docampo R. Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion. J Exp Med. 1994 Oct 01; 180(4):1535-40. PMID: 7931085; PMCID: PMC2191711.
    193. Moreno SN, Carnieri EG, Docampo R. Inhibition of Trypanosoma cruzi trypanothione reductase by crystal violet. Mol Biochem Parasitol. 1994 Oct; 67(2):313-20. PMID: 7870135.
      View in: PubMed
    194. Benaim G, Lopez-Estraño C, Docampo R, Moreno SN. A calmodulin-stimulated Ca2+ pump in plasma-membrane vesicles from Trypanosoma brucei; selective inhibition by pentamidine. Biochem J. 1993 Dec 15; 296 ( Pt 3):759-63. PMID: 8280074; PMCID: PMC1137760.
    195. Carnieri EG, Moreno SN, Docampo R. Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages. Mol Biochem Parasitol. 1993 Sep; 61(1):79-86. PMID: 8259135.
      View in: PubMed
    196. Docampo R, Moreno SN, Vercesi AE. Effect of thapsigargin on calcium homeostasis in Trypanosoma cruzi trypomastigotes and epimastigotes. Mol Biochem Parasitol. 1993 Jun; 59(2):305-13. PMID: 8341327.
      View in: PubMed
    197. Docampo R, Gadelha FR, Moreno SN, Benaim G, Hoffmann ME, Vercesi AE. Disruption of Ca2+ homeostasis in Trypanosoma cruzi by crystal violet. J Eukaryot Microbiol. 1993 May-Jun; 40(3):311-6. PMID: 8508168.
      View in: PubMed
    198. Vercesi AE, Moreno SN, Bernardes CF, Meinicke AR, Fernandes EC, Docampo R. Thapsigargin causes Ca2+ release and collapse of the membrane potential of Trypanosoma brucei mitochondria in situ and of isolated rat liver mitochondria. J Biol Chem. 1993 Apr 25; 268(12):8564-8. PMID: 8473301.
      View in: PubMed
    199. Vercesi AE, Hoffmann ME, Bernardes CF, Docampo R. ATP and Ca2+ homeostasis in Trypanosoma cruzi. Braz J Med Biol Res. 1993 Apr; 26(4):355-63. PMID: 8298511.
      View in: PubMed
    200. Docampo R. Calcium homeostasis in Trypanosoma cruzi. Biol Res. 1993; 26(1-2):189-96. PMID: 7545500.
      View in: PubMed
    201. Vercesi AE, Docampo R, Moreno SN. Energization-dependent Ca2+ accumulation in Trypanosoma brucei bloodstream and procyclic trypomastigotes mitochondria. Mol Biochem Parasitol. 1992 Dec; 56(2):251-7. PMID: 1484549.
      View in: PubMed
    202. Gadelha FR, Hanna PM, Mason RP, Docampo R. Evidence for free radical formation during horseradish peroxidase-catalyzed N-demethylation of crystal violet. Chem Biol Interact. 1992 Nov 30; 85(1):35-48. PMID: 1333891.
      View in: PubMed
    203. Vercesi AE, Docampo R. Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effects of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ. Biochem J. 1992 Jun 01; 284 ( Pt 2):463-7. PMID: 1376113; PMCID: PMC1132661.
    204. Moreno SN, Vercesi AE, Pignataro OP, Docampo R. Calcium homeostasis in Trypanosoma cruzi amastigotes: presence of inositol phosphates and lack of an inositol 1,4,5-trisphosphate-sensitive calcium pool. Mol Biochem Parasitol. 1992 Jun; 52(2):251-61. PMID: 1620163.
      View in: PubMed
    205. Moreno SN, Docampo R, Vercesi AE. Calcium homeostasis in procyclic and bloodstream forms of Trypanosoma brucei. Lack of inositol 1,4,5-trisphosphate-sensitive Ca2+ release. J Biol Chem. 1992 Mar 25; 267(9):6020-6. PMID: 1556113.
      View in: PubMed
    206. Benaim G, Losada S, Gadelha FR, Docampo R. A calmodulin-activated (Ca(2+)-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi. Biochem J. 1991 Dec 15; 280 ( Pt 3):715-20. PMID: 1837215; PMCID: PMC1130512.
    207. Vercesi AE, Bernardes CF, Hoffmann ME, Gadelha FR, Docampo R. Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ. J Biol Chem. 1991 Aug 05; 266(22):14431-4. PMID: 1860850.
      View in: PubMed
    208. Vercesi AE, Hoffmann ME, Bernardes CF, Docampo R. Regulation of intracellular calcium homeostasis in Trypanosoma cruzi. Effects of calmidazolium and trifluoperazine. Cell Calcium. 1991 May; 12(5):361-9. PMID: 1893396.
      View in: PubMed
    209. Docampo R, Pignataro OP. The inositol phosphate/diacylglycerol signalling pathway in Trypanosoma cruzi. Biochem J. 1991 Apr 15; 275 ( Pt 2):407-11. PMID: 2025225; PMCID: PMC1150068.
    210. Vercesi AE, Macedo DV, Lima SA, Gadelha FR, Docampo R. Ca2+ transport in digitonin-permeabilized trypanosomatids. Mol Biochem Parasitol. 1990 Aug; 42(1):119-24. PMID: 2233896.
      View in: PubMed
    211. Docampo R. Sensitivity of parasites to free radical damage by antiparasitic drugs. Chem Biol Interact. 1990; 73(1):1-27. PMID: 2406032.
      View in: PubMed
    212. Docampo R, Moreno SN. The metabolism and mode of action of gentian violet. Drug Metab Rev. 1990; 22(2-3):161-78. PMID: 2272286.
      View in: PubMed
    213. Docampo R, Vercesi AE. Characteristics of Ca2+ transport by Trypanosoma cruzi mitochondria in situ. Arch Biochem Biophys. 1989 Jul; 272(1):122-9. PMID: 2500059.
      View in: PubMed
    214. Gadelha FR, Moreno SN, De Souza W, Cruz FS, Docampo R. The mitochondrion of Trypanosoma cruzi is a target of crystal violet toxicity. Mol Biochem Parasitol. 1989 May 01; 34(2):117-26. PMID: 2540435.
      View in: PubMed
    215. Docampo R, Vercesi AE. Ca2+ transport by coupled Trypanosoma cruzi mitochondria in situ. J Biol Chem. 1989 Jan 05; 264(1):108-11. PMID: 2491844.
      View in: PubMed
    216. Docampo R, Moreno SN, Gadelha FR, de Souza W, Cruz FS. Prevention of Chagas' disease resulting from blood transfusion by treatment of blood: toxicity and mode of action of gentian violet. Biomed Environ Sci. 1988 Dec; 1(4):406-13. PMID: 3151757.
      View in: PubMed
    217. Moreno SN, Gadelha FR, Docampo R. Crystal violet as an uncoupler of oxidative phosphorylation in rat liver mitochondria. J Biol Chem. 1988 Sep 05; 263(25):12493-9. PMID: 2970460.
      View in: PubMed
    218. Docampo R, Moreno SN, Cruz FS. Enhancement of the cytotoxicity of crystal violet against Trypanosoma cruzi in the blood by ascorbate. Mol Biochem Parasitol. 1988 Jan 15; 27(2-3):241-7. PMID: 2830513.
      View in: PubMed
    219. Docampo R, Moreno SN, Mason RP. Generation of superoxide anion and hydrogen peroxide during redox cycling of 5-(4-nitrophenyl)-penta-2,4-dienal by mammalian microsomes and enzymes. Chem Biol Interact. 1988; 65(2):123-31. PMID: 2835186.
      View in: PubMed
    220. Moreno SN, Docampo R. Reduction of 5-nitroimidazoles, nitrofurazone, and 2,4-dinitrophenol to their free radical metabolites by Tritrichomonas foetus hydrogenosomes. Basic Life Sci. 1988; 49:759-64. PMID: 2855001.
      View in: PubMed
    221. Docampo R, Moreno SN, Mason RP. Free radical intermediates in the reaction of pyruvate:ferredoxin oxidoreductase in Tritrichomonas foetus hydrogenosomes. J Biol Chem. 1987 Sep 15; 262(26):12417-20. PMID: 3040744.
      View in: PubMed
    222. Albónico SM, Assem ME, Benages IA, Montiel AA, Pizzorno MT, Docampo R, Stoppani AO. Synthetic trypanocides: growth-inhibiting properties of new 1,2,3,4-tetrahydrocarbazoles on Trypanosoma cruzi. Rev Argent Microbiol. 1987 Jul-Sep; 19(3):121-4. PMID: 3332382.
      View in: PubMed
    223. Marr JJ, Docampo R. Chemotherapy for Chagas' disease: a perspective of current therapy and considerations for future research. Rev Infect Dis. 1986 Nov-Dec; 8(6):884-903. PMID: 3025994.
      View in: PubMed
    224. Docampo R, Moreno SN. Free radical metabolism of antiparasitic agents. Fed Proc. 1986 Sep; 45(10):2471-6. PMID: 3017765.
      View in: PubMed
    225. Reszka K, Cruz FS, Docampo R. Photosensitization by the trypanocidal agent crystal violet. Type I versus type II reactions. Chem Biol Interact. 1986 May; 58(2):161-72. PMID: 3013436.
      View in: PubMed
    226. Moreno SN, Docampo R. Reduction of the metallochromic indicators murexide and tetramethylmurexide to their free radical metabolites by cytoplasmic enzymes and reducing agents. Chem Biol Interact. 1986 Jan; 57(1):17-25. PMID: 3004749.
      View in: PubMed
    227. Moreno SN, Docampo R. Mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis. Environ Health Perspect. 1985 Dec; 64:199-208. PMID: 3830698; PMCID: PMC1568619.
    228. Moreno SN, Mason RP, Docampo R. Reduction of the metallochromic indicators arsenazo III and antipyrylazo III to their free radical metabolites by cytoplasmic enzymes. FEBS Lett. 1985 Jan 28; 180(2):229-33. PMID: 2981721.
      View in: PubMed
    229. Cardoni RL, de Titto EH, Docampo R. On the mechanism of killing of Trypanosoma cruzi by human polymorphonuclear leukocytes. Experientia. 1985 Jan 15; 41(1):89-91. PMID: 2981702.
      View in: PubMed
    230. Moreno SN, Mason RP, Docampo R. Ca2+ and Mg2+-enhanced reduction of arsenazo III to its anion free radical metabolite and generation of superoxide anion by an outer mitochondrial membrane azoreductase. J Biol Chem. 1984 Dec 10; 259(23):14609-16. PMID: 6094566.
      View in: PubMed
    231. Moreno SN, Mason RP, Docampo R. Distinct reduction of nitrofurans and metronidazole to free radical metabolites by Tritrichomonas foetus hydrogenosomal and cytosolic enzymes. J Biol Chem. 1984 Jul 10; 259(13):8252-9. PMID: 6330106.
      View in: PubMed
    232. Cruz FS, Lopes LA, De Souza W, Moreno SN, Mason RP, Docampo R. The photodynamic action of rose bengal on Trypanosoma cruzi. Acta Trop. 1984 Jun; 41(2):99-108. PMID: 6147990.
      View in: PubMed
    233. Moreno SN, Mason RP, Docampo R. Reduction of nifurtimox and nitrofurantoin to free radical metabolites by rat liver mitochondria. Evidence of an outer membrane-located nitroreductase. J Biol Chem. 1984 May 25; 259(10):6298-305. PMID: 6327675.
      View in: PubMed
    234. Docampo R, Moreno SN. Free radical metabolites in the mode of action of chemotherapeutic agents and phagocytic cells on Trypanosoma cruzi. Rev Infect Dis. 1984 Mar-Apr; 6(2):223-38. PMID: 6328615.
      View in: PubMed
    235. Docampo R, Moreno SN, Mason RP. Generation of free radical metabolites and superoxide anion by the calcium indicators arsenazo III, antipyrylazo III, and murexide in rat liver microsomes. J Biol Chem. 1983 Dec 25; 258(24):14920-5. PMID: 6317679.
      View in: PubMed
    236. Docampo R, Moreno SN, Muniz RP, Cruz FS, Mason RP. Light-enhanced free radical formation and trypanocidal action of gentian violet (crystal violet). Science. 1983 Jun 17; 220(4603):1292-5. PMID: 6304876.
      View in: PubMed
    237. Docampo R, Casellas AM, Madeira ED, Cardoni RL, Moreno SN, Mason RP. Oxygen-derived radicals from Trypanosoma cruzi-stimulated human neutrophils. FEBS Lett. 1983 May 02; 155(1):25-30. PMID: 6301881.
      View in: PubMed
    238. Moreno SN, Mason RP, Muniz RP, Cruz FS, Docampo R. Generation of free radicals from metronidazole and other nitroimidazoles by Tritrichomonas foetus. J Biol Chem. 1983 Apr 10; 258(7):4051-4. PMID: 6300071.
      View in: PubMed
    239. Dubin M, Moreno SN, Martino EE, Docampo R, Stoppani AO. Increased biliary secretion and loss of hepatic glutathione in rat liver after nifurtimox treatment. Biochem Pharmacol. 1983 Feb 01; 32(3):483-7. PMID: 6847698.
      View in: PubMed
    240. Moreno SN, Docampo R, Stoppani AO. [Undesirable effects of benznidazole and nifurtimox]. Medicina (B Aires). 1983; 43(3):291-5. PMID: 6323912.
      View in: PubMed
    241. Docampo R, Dubin M, Martino EE, Moreno SN, Stoppani AO. [Influence of nifurtimox on the glutathione content of the liver and bile in rats]. Medicina (B Aires). 1983; 43(1):33-40. PMID: 6877088.
      View in: PubMed
    242. Moreno SN, Docampo R, Mason RP, Leon W, Stoppani AO. Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations. Arch Biochem Biophys. 1982 Oct 15; 218(2):585-91. PMID: 6297399.
      View in: PubMed
    243. Cannata JJ, Valle E, Docampo R, Cazzulo JJ. Subcellular localization of phosphoenolpyruvate carboxykinase in the trypanosomatids Trypanosoma cruzi and Crithidia fasciculata. Mol Biochem Parasitol. 1982 Sep; 6(3):151-60. PMID: 6752707.
      View in: PubMed
    244. Cardoni RL, Docampo R, Casellas AM. Metabolic requirements for the damage of Trypanosoma cruzi epimastigotes by human polymorphonuclear leukocytes. J Parasitol. 1982 Aug; 68(4):547-52. PMID: 6288905.
      View in: PubMed
    245. Salzman TA, Stella AM, Wider de Xifra EA, Batlle AM, Docampo R, Stoppani AO. Porphyrin biosynthesis in parasitic hemoflagellates: functional and defective enzymes in Trypanosoma cruzi. Comp Biochem Physiol B. 1982; 72(4):663-7. PMID: 6751683.
      View in: PubMed
    246. Docampo R, Mason RP, Mottley C, Muniz RP. Generation of free radicals induced by nifurtimox in mammalian tissues. J Biol Chem. 1981 Nov 10; 256(21):10930-3. PMID: 6270136.
      View in: PubMed
    247. Docampo R, Moreno SN, Stoppani AO, Leon W, Cruz FS, Villalta F, Muniz RF. Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi. Biochem Pharmacol. 1981 Jul 15; 30(14):1947-51. PMID: 7023488.
      View in: PubMed
    248. Docampo R, Moreno SN, Turrens JF, Katzin AM, Gonzalez-Cappa SM, Stoppani AO. Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi. Mol Biochem Parasitol. 1981 Jul; 3(3):169-80. PMID: 6265775.
      View in: PubMed
    249. Docampo R, Moreno SN, Stoppani AO. Nitrofuran enhancement of microsomal electron transport, superoxide anion production and lipid peroxidation. Arch Biochem Biophys. 1981 Apr 01; 207(2):316-24. PMID: 6264859.
      View in: PubMed
    250. Stoppani AO, Docampo R, de Boiso JF, Frasch AC. Effect of inhibitors of electron transport and oxidative phosphorylation on Trypanosoma cruzi respiration and growth. Mol Biochem Parasitol. 1980 Oct; 2(1):3-21. PMID: 7007881.
      View in: PubMed
    251. Moreno SN, Palmero DJ, Eiguchi de Palmero K, Docampo R, Stoppani AO. [Stimulation of lipid peroxidation and ultrastructural changes induced by nifurtimox in mammalian tissue]. Medicina (B Aires). 1980 Sep-Oct; 40(5):553-9. PMID: 7207186.
      View in: PubMed
    252. Boveris A, Sies H, Martino EE, Docampo R, Turrens JF, Stoppani AO. Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi. Biochem J. 1980 Jun 15; 188(3):643-8. PMID: 7008779; PMCID: PMC1161944.
    253. Gonçalves AM, Vasconcellos ME, Docampo R, Cruz FS, de Souza W, Leon W. Evaluation of the toxicity of 3-allyl-beta-lapachone against Trypanosoma cruzi bloodstream forms. Mol Biochem Parasitol. 1980 Jun; 1(3):167-76. PMID: 6777696.
      View in: PubMed
    254. Cazzulo JJ, Valle E, Docampo R, Cannata JJ. Intracellular distribution of carbon dioxide-fixing enzymes in Trypanosoma cruzi and Crithidia fasciculata. J Gen Microbiol. 1980 Mar; 117(1):271-4. PMID: 6993627.
      View in: PubMed
    255. Cannata JJ, Docampo R, Valle E, Franke de Cazzulo BM, Cazzulo JJ. [Intracellular distribution of CO2-fixing enzymes in Trypanosoma cruzi and Crithidia fasciculata]. Medicina (B Aires). 1980; 40 Suppl 1:145-53. PMID: 6779078.
      View in: PubMed
    256. Docampo R, Stoppani AO. [Mechanism of the trypanocidal action of nifurtimox and other nitro-derivatives on Trypanosoma cruzi]. Medicina (B Aires). 1980; 40 Suppl 1:10-6. PMID: 6779074.
      View in: PubMed
    257. Docampo R, Stoppani AO. Generation of superoxide anion and hydrogen peroxide induced by nifurtimox in Trypanosoma cruzi. Arch Biochem Biophys. 1979 Oct 01; 197(1):317-21. PMID: 232403.
      View in: PubMed
    258. de Souza W, Souto-Padrón T, Docampo R, Chaves L, Leon W. The presence of basic proteins associated to the kinetoplast-DNA of Trypanosoma cruzi epimastigotes. Short communication. Acta Trop. 1979 Sep; 36(3):254-5. PMID: 43088.
      View in: PubMed
    259. Docampo R, Cruz FS, Leon W, Schmunis GA. Acetate oxidation by bloodstream forms of Trypanosoma cruzi. J Protozool. 1979 May; 26(2):301-3. PMID: 385857.
      View in: PubMed
    260. de Boiso JF, Docampo R, Stoppani AO, Frasch AC. [Effect of antimycin A on the respiration and growth of Trypanosoma cruzi]. Medicina (B Aires). 1979 May-Jun; 39(3):362-8. PMID: 390297.
      View in: PubMed
    261. Docampo R, Cruz FS, Boveris A, Muniz RP, Esquivel DM. beta-Lapachone enhancement of lipid peroxidation and superoxide anion and hydrogen peroxide formation by sarcoma 180 ascites tumor cells. Biochem Pharmacol. 1979 Mar 15; 28(6):723-8. PMID: 222291.
      View in: PubMed
    262. De Boiso JF, Docampo R, Stoppani AO. [Cytochromes in epimastigote form of Trypanosoma cruzi]. Rev Argent Microbiol. 1979 Jan-Apr; 11(1):22-36. PMID: 231798.
      View in: PubMed
    263. Lopes JN, Cruz FS, Docampo R, Vasconcellos ME, Sampaio MC, Pinto AV, Gilbert B. In vitro and in vivo evaluation of the toxicity of 1,4-naphthoquinone and 1,2-naphthoquinone derivatives against Trypanosoma cruzi. Ann Trop Med Parasitol. 1978 Dec; 72(6):523-31. PMID: 367298.
      View in: PubMed
    264. Cruz FS, Docampo R, Boveris A. Drugs inducing generation of free radicals in Trypanosoma cruzi [proceedings]. An Acad Bras Cienc. 1978 Dec; 50(4):598. PMID: 373539.
      View in: PubMed
    265. Docampo R, De Souza W, Cruz FS, Roitman I, Cover B, Gutteridge WE. Ultrastructural alterations and peroxide formation induced by naphthoquinones in different stages of Trypanosoma cruzi. Z Parasitenkd. 1978 Nov 27; 57(3):189-98. PMID: 216177.
      View in: PubMed
    266. Boveris A, Docampo R, Turrens JF, Stoppani AO. Effect of beta-lapachone on superoxide anion and hydrogen peroxide production in Trypanosoma cruzi. Biochem J. 1978 Nov 01; 175(2):431-9. PMID: 217340; PMCID: PMC1186088.
    267. Cruz FS, Docampo R, Boveris A. Generation of superoxide anions and hydrogen peroxide from beta-lapachone in bacteria. Antimicrob Agents Chemother. 1978 Oct; 14(4):630-3. PMID: 214029; PMCID: PMC352520.
    268. Docampo R, Cruz FS, Muniz RP, Esquivel DM, de Vasconcellos ME. Generation of free radicals from phenazine methosulfate in Trypanosoma cruzi epimastigotes. Acta Trop. 1978 Sep; 35(3):221-37. PMID: 31775.
      View in: PubMed
    269. Leon L, Vasconcellos ME, Leon W, Cruz FS, Docampo R, de Souza W. Trypanosoma cruzi: effect of olivacine on macromolecular synthesis, ultrastructure, and respiration of epimastigotes. Exp Parasitol. 1978 Aug; 45(2):151-9. PMID: 98344.
      View in: PubMed
    270. Docampo R, de Boiso JF, Stoppani AO. Tricarboxylic acid cycle operation at the kinetoplast-mitochondrion complex of Trypanosoma cruzi. Biochim Biophys Acta. 1978 Jun 08; 502(3):466-76. PMID: 350277.
      View in: PubMed
    271. Docampo R, Cruz FS, Boveris A, Muniz RP, Esquivel DM. Lipid peroxidation and the generation of free radicals, superoxide anion, and hydrogen peroxide in beta-lapachone-treated Trypanosoma cruzi epimastigotes. Arch Biochem Biophys. 1978 Mar; 186(2):292-7. PMID: 205176.
      View in: PubMed
    272. Cruz FS, Docampo R, de Souza W. Effect of beta-lapachone on hydrogen peroxide production in Trypanosoma cruzi. Acta Trop. 1978 Mar; 35(1):35-40. PMID: 24995.
      View in: PubMed
    273. Boveris A, Stoppani AO, Docampo R, Cruz FS. Superoxide anion production and trypanocidal action of naphthoquinones on Trypanosoma cruzi. Comp Biochem Physiol C. 1978; 61 C(2):327-9. PMID: 33002.
      View in: PubMed
    274. Docampo R, Lopes JN, Cruz FS, Souza W. Trypanosoma cruzi: ultrastructural and metabolic alterations of epimastigotes by beta-lapachone. Exp Parasitol. 1977 Jun; 42(1):142-9. PMID: 324785.
      View in: PubMed
    275. Boveris A, Docampo R, Turrens JF, Stoppani AO. [Effect of beta and alpha-lapachone on the production of H202 and on the growth of Trypanosoma cruzi]. Rev Asoc Argent Microbiol. 1977 May-Aug; 9(2):54-61. PMID: 339293.
      View in: PubMed
    276. Docampo R, de Boiso JF, Boveris A, Stoppani AO. Localization of peroxidase activity in Trypanosoma cruzi microbodies. Experientia. 1976 Aug 15; 32(8):972-5. PMID: 782907.
      View in: PubMed
    277. de Boiso JF, Docampo R, Stoppani AO. [Ultrastructure of Trypanosoma cruzi with scanning and transmission electromicroscopy]. Rev Asoc Argent Microbiol. 1974 Sep-Dec; 6(3):119-26. PMID: 4377466.
      View in: PubMed
    278. Docampo R, de Boiso JF, Stoppani AO. [Metabolic changes in diskinetoplastic Trypanosoma cruzi by ethidium bromide action]. Medicina (B Aires). 1974 Sep-Oct; 34(5):525-31. PMID: 4612292.
      View in: PubMed
    279. Docampo R, de Boiso JF, Stoppani AO. [Metabolic differences in Trypanosoma cruzi depending of the culturing conditions]. Rev Asoc Argent Microbiol. 1974 Jan-Apr; 6(1):7-14. PMID: 4619479.
      View in: PubMed
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