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Professor Mark Hamann

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Waters AL, Oh J, Place AR, Hamann MT. Stereochemical Studies of the Karlotoxin Class Using NMR Spectroscopy and DP4 Chemical-Shift Analysis: Insights into their Mechanism of Action. Angew Chem Int Ed Engl. 2015 Dec 21; 54(52):15705-10. PMID: 26568046; PMCID: PMC4870721 [Available on 12/21/16].
    2. Gogineni V, Schinazi RF, Hamann MT. Role of Marine Natural Products in the Genesis of Antiviral Agents. Chem Rev. 2015 Sep 23; 115(18):9655-706. PMID: 26317854; PMCID: PMC4883660.
    3. Zhang Y, Valeriote F, Swartz K, Chen B, Hamann MT, Rodenburg DL, McChesney JD, Shaw J. HPLC Plasma Assay of a Novel Anti-MRSA Compound, Kaempferol-3-O-Alpha-L-(2",3"-di-p-coumaroyl)rhamnoside, from Sycamore Leaves. Nat Prod Commun. 2015 Aug; 10(8):1383-6. PMID: 26434123; PMCID: PMC4895204.
    4. Wang B, Waters AL, Valeriote FA, Hamann MT. An efficient and cost-effective approach to kahalalide F N-terminal modifications using a nuisance algal bloom of Bryopsis pennata. Biochim Biophys Acta. 2015 Sep; 1850(9):1849-54. PMID: 25964068; PMCID: PMC4516563.
    5. Hwang IH, Oh J, Zhou W, Park S, Kim JH, Chittiboyina AG, Ferreira D, Song GY, Oh S, Na M, Hamann MT. Cytotoxic activity of rearranged drimane meroterpenoids against colon cancer cells via down-regulation of ß-catenin expression. J Nat Prod. 2015 Mar 27; 78(3):453-61. PMID: 25590830; PMCID: PMC4380199.
    6. He Y, Peng J, Hamann MT, West LM. An iridoid glucoside and the related aglycones from Cornus florida. J Nat Prod. 2014 Sep 26; 77(9):2138-43. PMID: 25141901; PMCID: PMC4176392.
    7. Cox DG, Oh J, Keasling A, Colson KL, Hamann MT. The utility of metabolomics in natural product and biomarker characterization. Biochim Biophys Acta. 2014 Dec; 1840(12):3460-3474. PMID: 25151044.
      View in: PubMed
    8. Yang F, Zou Y, Wang RP, Hamann MT, Zhang HJ, Jiao WH, Han BN, Song SJ, Lin HW. Relative and absolute stereochemistry of diacarperoxides: antimalarial norditerpene endoperoxides from marine sponge Diacarnus megaspinorhabdosa. Mar Drugs. 2014 Aug 08; 12(8):4399-416. PMID: 25110917; PMCID: PMC4145323.
    9. Falodun A, Imieje V, Erharuyi O, Ahomafor J, Jacob MR, Khan SI, Hamann MT. Evaluation of three medicinal plant extracts against Plasmodium falciparum and selected microganisms. Afr J Tradit Complement Altern Med. 2014; 11(4):142-6. PMID: 25392594; PMCID: PMC4202410.
    10. Falodun A, Imieje V, Erharuyi O, Joy A, Langer P, Jacob M, Khan S, Abaldry M, Hamann M. Isolation of antileishmanial, antimalarial and antimicrobial metabolites from Jatropha multifida. Asian Pac J Trop Biomed. 2014 May; 4(5):374-8. PMID: 25182722; PMCID: PMC3985052.
    11. Stoddard SV, Hamann MT, Wadkins RM. Insights and ideas garnered from marine metabolites for development of dual-function acetylcholinesterase and amyloid-ß aggregation inhibitors. Mar Drugs. 2014 Apr 04; 12(4):2114-31. PMID: 24714126; PMCID: PMC4012451.
    12. Zhou W, Oh J, Wonhwa L, Kwak S, Li W, Chittiboyina AG, Ferreira D, Hamann MT, Lee SH, Bae JS, Na M. The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis. Biochim Biophys Acta. 2014 Jun; 1840(6):2042-9. PMID: 24576671; PMCID: PMC4149911.
    13. Kasanah N, Farr LL, Gholipour A, Wedge DE, Hamann MT. Metabolism and resistance of Fusarium spp. to the manzamine alkaloids via a putative retro pictet-spengler reaction and utility of the rational design of antimalarial and antifungal agents. Mar Biotechnol (NY). 2014 Aug; 16(4):412-22. PMID: 24553735; PMCID: PMC4139108.
    14. Li H, Su M, Hamann MT, Bowling JJ, Kim HS, Jung JH. Solution structure of a sponge-derived cystine knot peptide and its notable stability. J Nat Prod. 2014 Feb 28; 77(2):304-10. PMID: 24499386; PMCID: PMC4128683.
    15. O'Shea OR, Hamann M, Smith W, Taylor H. Predictable pollution: an assessment of weather balloons and associated impacts on the marine environment--an example for the Great Barrier Reef, Australia. Mar Pollut Bull. 2014 Feb 15; 79(1-2):61-8. PMID: 24434000.
      View in: PubMed
    16. Li H, Bowling JJ, Su M, Hong J, Lee BJ, Hamann MT, Jung JH. Asteropsins B-D, sponge-derived knottins with potential utility as a novel scaffold for oral peptide drugs. Biochim Biophys Acta. 2014 Mar; 1840(3):977-84. PMID: 24225326; PMCID: PMC4139099.
    17. Ibrahim MA, Na M, Oh J, Schinazi RF, McBrayer TR, Whitaker T, Doerksen RJ, Newman DJ, Zachos LG, Hamann MT. Significance of endangered and threatened plant natural products in the control of human disease. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):16832-7. PMID: 24082148; PMCID: PMC3801070.
    18. Davis J, Fricke WF, Hamann MT, Esquenazi E, Dorrestein PC, Hill RT. Characterization of the bacterial community of the chemically defended Hawaiian sacoglossan Elysia rufescens. Appl Environ Microbiol. 2013 Nov; 79(22):7073-81. PMID: 24014539; PMCID: PMC3811551.
    19. Oh J, Bowling JJ, Zou Y, Chittiboyina AG, Doerksen RJ, Ferreira D, Leininger TD, Hamann MT. Configurational assignments of conformationally restricted bis-monoterpene hydroquinones: utility in exploration of endangered plants. Biochim Biophys Acta. 2013 Aug; 1830(8):4229-34. PMID: 23628705; PMCID: PMC4139972.
    20. Wang B, Waters AL, Sims JW, Fullmer A, Ellison S, Hamann MT. Complex marine natural products as potential epigenetic and production regulators of antibiotics from a marine Pseudomonas aeruginosa. Microb Ecol. 2013 May; 65(4):1068-75. PMID: 23563743; PMCID: PMC3650628.
    21. Zou Y, Hamann MT. Atkamine: a new pyrroloiminoquinone scaffold from the cold water Aleutian Islands Latrunculia sponge. Org Lett. 2013 Apr 05; 15(7):1516-9. PMID: 23472820; PMCID: PMC4137554.
    22. Li H, Bowling JJ, Fronczek FR, Hong J, Jabba SV, Murray TF, Ha NC, Hamann MT, Jung JH. Asteropsin A: an unusual cystine-crosslinked peptide from porifera enhances neuronal Ca2+ influx. Biochim Biophys Acta. 2013 Mar; 1830(3):2591-9. PMID: 23201194; PMCID: PMC4137556.
    23. Albadry MA, Elokely KM, Wang B, Bowling JJ, Abdelwahab MF, Hossein MH, Doerksen RJ, Hamann MT. Computationally assisted assignment of kahalalide Y configuration using an NMR-constrained conformational search. J Nat Prod. 2013 Feb 22; 76(2):178-85. PMID: 23363083; PMCID: PMC3583380.
    24. Oh J, Bowling JJ, Carroll JF, Demirci B, Baser KH, Leininger TD, Bernier UR, Hamann MT. Natural product studies of U.S. endangered plants: volatile components of Lindera melissifolia (Lauraceae) repel mosquitoes and ticks. Phytochemistry. 2012 Aug; 80:28-36. PMID: 22704653; PMCID: PMC4144860.
    25. Wahba AE, Hamann MT. Reductive N-alkylation of nitroarenes: a green approach for the N-alkylation of natural products. J Org Chem. 2012 May 18; 77(10):4578-85. PMID: 22482705; PMCID: PMC4883703.
    26. Yang F, Hamann MT, Zou Y, Zhang MY, Gong XB, Xiao JR, Chen WS, Lin HW. Antimicrobial metabolites from the Paracel Islands sponge Agelas mauritiana. J Nat Prod. 2012 Apr 27; 75(4):774-8. PMID: 22360686; PMCID: PMC4883697.
    27. He YQ, Ma GY, Peng JN, Ma ZY, Hamann MT. Liver X receptor and peroxisome proliferator-activated receptor agonist from Cornus alternifolia. Biochim Biophys Acta. 2012 Jul; 1820(7):1021-6. PMID: 22353334; PMCID: PMC3482494.
    28. Abbas S, Kelly M, Bowling J, Sims J, Waters A, Hamann M. Advancement into the Arctic region for bioactive sponge secondary metabolites. Mar Drugs. 2011; 9(11):2423-37. PMID: 22163194; PMCID: PMC3229243.
    29. Shilabin AG, Hamann MT. In vitro and in vivo evaluation of select kahalalide F analogs with antitumor and antifungal activities. Bioorg Med Chem. 2011 Nov 15; 19(22):6628-32. PMID: 21839640; PMCID: PMC3523750.
    30. Gao J, Hamann MT. Chemistry and biology of kahalalides. Chem Rev. 2011 May 11; 111(5):3208-35. PMID: 21480581; PMCID: PMC4895206.
    31. Xu T, Feng Q, Jacob MR, Avula B, Mask MM, Baerson SR, Tripathi SK, Mohammed R, Hamann MT, Khan IA, Walker LA, Clark AM, Agarwal AK. The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis. Antimicrob Agents Chemother. 2011 Apr; 55(4):1611-21. PMID: 21300833; PMCID: PMC3067192.
    32. Waters AL, Hill RT, Place AR, Hamann MT. The expanding role of marine microbes in pharmaceutical development. Curr Opin Biotechnol. 2010 Dec; 21(6):780-6. PMID: 20956080; PMCID: PMC2994104.
    33. Wahba AE, Hamann MT. New one-pot methodologies for the modification or synthesis of alkaloid scaffolds. Mar Drugs. 2010 Aug 24; 8(8):2395-416. PMID: 20948914; PMCID: PMC2953410.
    34. Kochanowska-Karamyan AJ, Hamann MT. Marine indole alkaloids: potential new drug leads for the control of depression and anxiety. Chem Rev. 2010 Aug 11; 110(8):4489-97. PMID: 20380420; PMCID: PMC2922063.
    35. Rodrigo G, Almanza GR, Cheng Y, Peng J, Hamann M, Duan RD, Akesson B. Antiproliferative effects of curcuphenol, a sesquiterpene phenol. Fitoterapia. 2010 Oct; 81(7):762-6. PMID: 20385210.
      View in: PubMed
    36. Na M, Ding Y, Wang B, Tekwani BL, Schinazi RF, Franzblau S, Kelly M, Stone R, Li XC, Ferreira D, Hamann MT. Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia. J Nat Prod. 2010 Mar 26; 73(3):383-7. PMID: 20337497; PMCID: PMC4883701.
    37. Peng J, Place AR, Yoshida W, Anklin C, Hamann MT. Structure and absolute configuration of karlotoxin-2, an ichthyotoxin from the marine dinoflagellate Karlodinium veneficum. J Am Chem Soc. 2010 Mar 17; 132(10):3277-9. PMID: 20155901; PMCID: PMC2836391.
    38. Peng J, Kudrimoti S, Prasanna S, Odde S, Doerksen RJ, Pennaka HK, Choo YM, Rao KV, Tekwani BL, Madgula V, Khan SI, Wang B, Mayer AM, Jacob MR, Tu LC, Gertsch J, Hamann MT. Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections. J Med Chem. 2010 Jan 14; 53(1):61-76. PMID: 20017491; PMCID: PMC2834284.
    39. Gao J, Caballero-George C, Wang B, Rao KV, Shilabin AG, Hamann MT. 5-OHKF and NorKA, depsipeptides from a Hawaiian collection of Bryopsis pennata: binding properties for NorKA to the human neuropeptide Y Y1 receptor. J Nat Prod. 2009 Dec; 72(12):2172-6. PMID: 19916528; PMCID: PMC4895201.
    40. Ibrahim MA, Mansoor AA, Gross A, Ashfaq MK, Jacob M, Khan SI, Hamann MT. Methicillin-resistant Staphylococcus aureus (MRSA)-active metabolites from Platanus occidentalis (American Sycamore). J Nat Prod. 2009 Dec; 72(12):2141-4. PMID: 19904995; PMCID: PMC4883668.
    41. Meujo DA, Kevin DA, Peng J, Bowling JJ, Liu J, Hamann MT. Reducing oyster-associated bacteria levels using supercritical fluid CO2 as an agent of warm pasteurization. Int J Food Microbiol. 2010 Mar 31; 138(1-2):63-70. PMID: 20022650; PMCID: PMC2830373.
    42. Wahba AE, Peng J, Kudrimoti S, Tekwani BL, Hamann MT. Structure-activity relationship studies of manzamine A: amidation of positions 6 and 8 of the beta-carboline moiety. Bioorg Med Chem. 2009 Nov 15; 17(22):7775-82. PMID: 19833520; PMCID: PMC4883699.
    43. Kudrimoti S, Ahmed SA, Daga PR, Wahba AE, Khalifa SI, Doerksen RJ, Hamann MT. Semisynthetic latrunculin B analogs: studies of actin docking support a proposed mechanism for latrunculin bioactivity. Bioorg Med Chem. 2009 Nov 01; 17(21):7517-22. PMID: 19800245; PMCID: PMC2782694.
    44. Genovese G, Tedone L, Hamann MT, Morabito M. The Mediterranean red alga Asparagopsis: a source of compounds against Leishmania. Mar Drugs. 2009 Aug 11; 7(3):361-6. PMID: 19841720; PMCID: PMC2763106.
    45. Mayer AM, Rodríguez AD, Berlinck RG, Hamann MT. Marine pharmacology in 2005-6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Biochim Biophys Acta. 2009 May; 1790(5):283-308. PMID: 19303911; PMCID: PMC2735450.
    46. Kevin Ii DA, Meujo DA, Hamann MT. Polyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasites. Expert Opin Drug Discov. 2009 Feb; 4(2):109-46. PMID: 23480512; PMCID: PMC4896753.
    47. Wu SB, Zhao Y, Fan H, Hu YH, Hamann MT, Peng JN, Starks CM, O'Neil-Johnson M, Hu JF. New guaiane sesquiterpenes and furanocoumarins from Notopterygium incisum. Planta Med. 2008 Dec; 74(15):1812-7. PMID: 18991202; PMCID: PMC4883698.
    48. Shilabin AG, Kasanah N, Tekwani BL, Hamann MT. Kinetic studies and bioactivity of potential manzamine prodrugs. J Nat Prod. 2008 Jul; 71(7):1218-21. PMID: 18598080; PMCID: PMC4918903.
    49. Donia MS, Wang B, Dunbar DC, Desai PV, Patny A, Avery M, Hamann MT. Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle. J Nat Prod. 2008 Jun; 71(6):941-5. PMID: 18543965; PMCID: PMC2651694.
    50. Ibrahim MA, Shilabin AG, Prasanna S, Jacob M, Khan SI, Doerksen RJ, Hamann MT. 2-N-Methyl modifications and SAR studies of manzamine A. Bioorg Med Chem. 2008 Jul 15; 16(14):6702-6. PMID: 18595720; PMCID: PMC2547340.
    51. Mohamed NM, Rao V, Hamann MT, Kelly M, Hill RT. Monitoring bacterial diversity of the marine sponge Ircinia strobilina upon transfer into aquaculture. Appl Environ Microbiol. 2008 Jul; 74(13):4133-43. PMID: 18469126; PMCID: PMC2446523.
    52. Rao KV, Na MK, Cook JC, Peng J, Matsumoto R, Hamann MT. Kahalalides V-Y isolated from a Hawaiian collection of the sacoglossan mollusk Elysia rufescens. J Nat Prod. 2008 May; 71(5):772-8. PMID: 18407693; PMCID: PMC4918905.
    53. Ahmed SA, Khalifa SI, Hamann MT. Antiepileptic ceramides from the Red Sea sponge Negombata corticata. J Nat Prod. 2008 Apr; 71(4):513-5. PMID: 18355032; PMCID: PMC4907267.
    54. Bowling JJ, Pennaka HK, Ivey K, Wahyuono S, Kelly M, Schinazi RF, Valeriote FA, Graves DE, Hamann MT. Antiviral and anticancer optimization studies of the DNA-binding marine natural product aaptamine. Chem Biol Drug Des. 2008 Mar; 71(3):205-15. PMID: 18251774; PMCID: PMC4918911.
    55. Kochanowska AJ, Rao KV, Childress S, El-Alfy A, Matsumoto RR, Kelly M, Stewart GS, Sufka KJ, Hamann MT. Secondary metabolites from three Florida sponges with antidepressant activity. J Nat Prod. 2008 Feb; 71(2):186-9. PMID: 18217716; PMCID: PMC4918908.
    56. Sayed KA, Khalil AA, Yousaf M, Labadie G, Kumar GM, Franzblau SG, Mayer AM, Avery MA, Hamann MT. Semisynthetic studies on the manzamine alkaloids. J Nat Prod. 2008 Mar; 71(3):300-8. PMID: 18198837; PMCID: PMC4895205.
    57. Fan H, Peng J, Hamann MT, Hu JF. Lamellarins and related pyrrole-derived alkaloids from marine organisms. Chem Rev. 2008 Jan; 108(1):264-87. PMID: 18095718; PMCID: PMC4928200.
    58. Diers JA, Ivey KD, El-Alfy A, Shaikh J, Wang J, Kochanowska AJ, Stoker JF, Hamann MT, Matsumoto RR. Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. Pharmacol Biochem Behav. 2008 Mar; 89(1):46-53. PMID: 18037479; PMCID: PMC4480916.
    59. Bowling JJ, Kochanowska AJ, Kasanah N, Hamann MT. Nature's bounty - drug discovery from the sea. Expert Opin Drug Discov. 2007 Nov; 2(11):1505-22. PMID: 23484601; PMCID: PMC4928193.
    60. Ahmed SA, Odde S, Daga PR, Bowling JJ, Mesbah MK, Youssef DT, Khalifa SI, Doerksen RJ, Hamann MT. Latrunculin with a highly oxidized thiazolidinone ring: structure assignment and actin docking. Org Lett. 2007 Nov 08; 9(23):4773-6. PMID: 17929935; PMCID: PMC2529398.
    61. Winkler JD, Londregan AT, Hamann MT. Synthetic modification of manzamine A via Grubbs metathesis. Novel structures with enhanced antibacterial and antiprotozoal properties. Org Lett. 2007 Oct 25; 9(22):4467-9. PMID: 17918854; PMCID: PMC4918910.
    62. Hamann M, Alonso D, Martín-Aparicio E, Fuertes A, Pérez-Puerto MJ, Castro A, Morales S, Navarro ML, Del Monte-Millán M, Medina M, Pennaka H, Balaiah A, Peng J, Cook J, Wahyuono S, Martínez A. Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease. J Nat Prod. 2007 Sep; 70(9):1397-405. PMID: 17708655.
      View in: PubMed
    63. Shilabin AG, Kasanah N, Wedge DE, Hamann MT. Lysosome and HER3 (ErbB3) selective anticancer agent kahalalide F: semisynthetic modifications and antifungal lead-exploration studies. J Med Chem. 2007 Sep 06; 50(18):4340-50. PMID: 17696332; PMCID: PMC4917214.
    64. Gul W, Hammond NL, Yousaf M, Peng J, Holley A, Hamann MT. Chemical transformation and biological studies of marine sesquiterpene (S)-(+)-curcuphenol and its analogs. Biochim Biophys Acta. 2007 Nov; 1770(11):1513-9. PMID: 17804167; PMCID: PMC2266081.
    65. Mayer AM, Rodríguez AD, Berlinck RG, Hamann MT. Marine pharmacology in 2003-4: marine compounds with anthelmintic antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action. Comp Biochem Physiol C Toxicol Pharmacol. 2007 May; 145(4):553-81. PMID: 17392033; PMCID: PMC2151674.
    66. Hamann MT. The manzamines as an example of the unique structural classes available for the discovery and optimization of infectious disease controls based on marine natural products. Curr Pharm Des. 2007; 13(6):653-60. PMID: 17346180; PMCID: PMC4918914.
    67. Mohammed R, Peng J, Kelly M, Hamann MT. Cyclic heptapeptides from the Jamaican sponge Stylissa caribica. J Nat Prod. 2006 Dec; 69(12):1739-44. PMID: 17190452; PMCID: PMC4928197.
    68. Gul W, Hammond NL, Yousaf M, Bowling JJ, Schinazi RF, Wirtz SS, de Castro Andrews G, Cuevas C, Hamann MT. Modification at the C9 position of the marine natural product isoaaptamine and the impact on HIV-1, mycobacterial, and tumor cell activity. Bioorg Med Chem. 2006 Dec 15; 14(24):8495-505. PMID: 17045480; PMCID: PMC4928486.
    69. Winkler JD, Londregan AT, Ragains JR, Hamann MT. Synthesis and biological evaluation of manzamine analogues. Org Lett. 2006 Jul 20; 8(15):3407-9. PMID: 16836417; PMCID: PMC4918913.
    70. Rao KV, Donia MS, Peng J, Garcia-Palomero E, Alonso D, Martinez A, Medina M, Franzblau SG, Tekwani BL, Khan SI, Wahyuono S, Willett KL, Hamann MT. Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases. J Nat Prod. 2006 Jul; 69(7):1034-40. PMID: 16872140; PMCID: PMC4917200.
    71. Winkler JD, Londregan AT, Hamann MT. Antimalarial activity of a new family of analogues of manzamine A. Org Lett. 2006 Jun 08; 8(12):2591-4. PMID: 16737321; PMCID: PMC4918909.
    72. Diers JA, Bowling JJ, Duke SO, Wahyuono S, Kelly M, Hamann MT. Zebra mussel antifouling activity of the marine natural product aaptamine and analogs. Mar Biotechnol (NY). 2006 Jul-Aug; 8(4):366-72. PMID: 16718618; PMCID: PMC4917205.
    73. Peng J, Kasanah N, Stanley CE, Chadwick J, Fronczek FR, Hamann MT. Microbial metabolism studies of cyanthiwigin B and synergetic antibiotic effects. J Nat Prod. 2006 May; 69(5):727-30. PMID: 16724830; PMCID: PMC2532061.
    74. Robert F, Gao HQ, Donia M, Merrick WC, Hamann MT, Pelletier J. Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis. RNA. 2006 May; 12(5):717-25. PMID: 16540697; PMCID: PMC1440909.
    75. Khalifa S, Ahmed S, Mesbah M, Youssef D, Hamann M. Quantitative determination of latrunculins A and B in the Red Sea sponge Negombata magnifica by high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 17; 832(1):47-51. PMID: 16431167.
      View in: PubMed
    76. Gul W, Hamann MT. Indole alkaloid marine natural products: an established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases. Life Sci. 2005 Dec 22; 78(5):442-53. PMID: 16236327; PMCID: PMC4918921.
    77. Kasanah N, Hamann MT. SPK-843 (Aparts/Kaken). Curr Opin Investig Drugs. 2005 Aug; 6(8):845-53. PMID: 16121692; PMCID: PMC4928195.
    78. Bourel-Bonnet L, Rao KV, Hamann MT, Ganesan A. Solid-phase total synthesis of kahalalide A and related analogues. J Med Chem. 2005 Mar 10; 48(5):1330-5. PMID: 15743176; PMCID: PMC4917212.
    79. Mayer AM, Hamann MT. Marine pharmacology in 2001--2002: marine compounds with anthelmintic, antibacterial, anticoagulant, antidiabetic, antifungal, anti-inflammatory, antimalarial, antiplatelet, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems and other miscellaneous mechanisms of action. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Mar-Apr; 140(3-4):265-86. PMID: 15919242; PMCID: PMC4928201.
    80. Peng J, Li J, Hamann MT. The marine bromotyrosine derivatives. Alkaloids Chem Biol. 2005; 61:59-262. PMID: 16173400; PMCID: PMC4943341.
    81. Hua HM, Peng J, Fronczek FR, Kelly M, Hamann MT. Crystallographic and NMR studies of antiinfective tricyclic guanidine alkaloids from the sponge Monanchora unguifera. Bioorg Med Chem. 2004 Dec 15; 12(24):6461-4. PMID: 15556763; PMCID: PMC4969008.
    82. Diers JA, Pennaka HK, Peng J, Bowling JJ, Duke SO, Hamann MT. Structural activity relationship studies of zebra mussel antifouling and antimicrobial agents from verongid sponges. J Nat Prod. 2004 Dec; 67(12):2117-20. PMID: 15620267; PMCID: PMC4928192.
    83. Hamann MT. Technology evaluation: Kahalalide F, PharmaMar. Curr Opin Mol Ther. 2004 Dec; 6(6):657-65. PMID: 15663330; PMCID: PMC4941207.
    84. Kasanah N, Hamann MT. Development of antibiotics and the future of marine microorganisms to stem the tide of antibiotic resistance. Curr Opin Investig Drugs. 2004 Aug; 5(8):827-37. PMID: 15600239; PMCID: PMC4969015.
    85. Rao KV, Kasanah N, Wahyuono S, Tekwani BL, Schinazi RF, Hamann MT. Three new manzamine alkaloids from a common Indonesian sponge and their activity against infectious and tropical parasitic diseases. J Nat Prod. 2004 Aug; 67(8):1314-8. PMID: 15332848; PMCID: PMC4928196.
    86. Yousaf M, Hammond NL, Peng J, Wahyuono S, McIntosh KA, Charman WN, Mayer AM, Hamann MT. New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections, and inflammatory diseases. J Med Chem. 2004 Jul 01; 47(14):3512-7. PMID: 15214779; PMCID: PMC4928483.
    87. Peng J, Avery MA, Hamann MT. Cyanthiwigin AC and AD, two novel diterpene skeletons from the Jamaican sponge Myrmekioderma styx. Org Lett. 2003 Nov 27; 5(24):4575-8. PMID: 14627387; PMCID: PMC4928198.
    88. Peng J, Hu JF, Kazi AB, Li Z, Avery M, Peraud O, Hill RT, Franzblau SG, Zhang F, Schinazi RF, Wirtz SS, Tharnish P, Kelly M, Wahyuono S, Hamann MT. Manadomanzamines A and B: a novel alkaloid ring system with potent activity against mycobacteria and HIV-1. J Am Chem Soc. 2003 Nov 05; 125(44):13382-6. PMID: 14583033; PMCID: PMC4928190.
    89. Mayer AM, Hamann MT. Marine pharmacology in 2000: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antituberculosis, and antiviral activities; affecting the cardiovascular, immune, and nervous systems and other miscellaneous mechanisms of action. Mar Biotechnol (NY). 2004 Jan-Feb; 6(1):37-52. PMID: 14583811; PMCID: PMC4934889.
    90. Gochfeld DJ, El Sayed KA, Yousaf M, Hu JF, Bartyzel P, Dunbar DC, Wilkins SP, Zjawiony JK, Schinazi RF, Schlueter Wirtz S, Tharnish PM, Hamann MT. Marine natural products as lead anti-HIV agents. Mini Rev Med Chem. 2003 Aug; 3(5):401-24. PMID: 12769693.
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    91. Rao KV, Santarsiero BD, Mesecar AD, Schinazi RF, Tekwani BL, Hamann MT. New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. J Nat Prod. 2003 Jun; 66(6):823-8. PMID: 12828469; PMCID: PMC4969047.
    92. Khalil A, El-Sayed K, Belal F, Khalil NY, Hamann M. Spectrofluorimetric determination of manzamine A in spiked human urine and plasma. Pharmazie. 2003 Jun; 58(6):385-8. PMID: 12856999.
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    93. Donia M, Hamann MT. Marine natural products and their potential applications as anti-infective agents. Lancet Infect Dis. 2003 Jun; 3(6):338-48. PMID: 12781505.
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    94. Takamatsu S, Hodges TW, Rajbhandari I, Gerwick WH, Hamann MT, Nagle DG. Marine natural products as novel antioxidant prototypes. J Nat Prod. 2003 May; 66(5):605-8. PMID: 12762791; PMCID: PMC4969048.
    95. Peng J, Shen X, El Sayed KA, Dunbar DC, Perry TL, Wilkins SP, Hamann MT, Bobzin S, Huesing J, Camp R, Prinsen M, Krupa D, Wideman MA. Marine natural products as prototype agrochemical agents. J Agric Food Chem. 2003 Apr 09; 51(8):2246-52. PMID: 12670165; PMCID: PMC4969014.
    96. Duncan CJ, Cuendet M, Fronczek FR, Pezzuto JM, Mehta RG, Hamann MT, Ross SA. Chemical and biological investigation of the fungus Pulveroboletus ravenelii. J Nat Prod. 2003 Jan; 66(1):103-7. PMID: 12542354; PMCID: PMC4969011.
    97. Hamann MT. Enhancing marine natural product structural diversity and bioactivity through semisynthesis and biocatalysis. Curr Pharm Des. 2003; 9(11):879-89. PMID: 12678872.
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    98. Hu JF, Hamann MT, Hill R, Kelly M. The manzamine alkaloids. Alkaloids Chem Biol. 2003; 60:207-85. PMID: 14593858.
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    99. Orabi KY, El Sayed KA, Hamann MT, Dunbar DC, Al-Said MS, Higa T, Kelly M. Araguspongines K and L, new bioactive bis-1-oxaquinolizidine N-oxide alkaloids from Red Sea specimens of Xestospongia exigua. J Nat Prod. 2002 Dec; 65(12):1782-5. PMID: 12502314; PMCID: PMC4969009.
    100. Wilkins SP, Blum AJ, Burkepile DE, Rutland TJ, Wierzbicki A, Kelly M, Hamann MT. Isolation of an antifreeze peptide from the Antarctic sponge Homaxinella balfourensis. Cell Mol Life Sci. 2002 Dec; 59(12):2210-5. PMID: 12568347; PMCID: PMC4969016.
    101. El Sayed KA, Yousaf M, Hamann MT, Avery MA, Kelly M, Wipf P. Microbial and chemical transformation studies of the bioactive marine sesquiterpenes (S)-(+)-curcuphenol and -curcudiol isolated from a deep reef collection of the Jamaican sponge Didiscus oxeata. J Nat Prod. 2002 Nov; 65(11):1547-53. PMID: 12444675.
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    102. Hu JF, Kelly M, Hamann MT. 26-Nor-25-isopropyl-ergosta-5,7,22E-trien-3beta-ol: a new C(29) sterol from the sponge Agelas sceptrum from Jamaica. Steroids. 2002 Aug; 67(9):743-7. PMID: 12123785.
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    103. Mayer AM, Hamann MT. Marine pharmacology in 1999: compounds with antibacterial, anticoagulant, antifungal, anthelmintic, anti-inflammatory, antiplatelet, antiprotozoal and antiviral activities affecting the cardiovascular, endocrine, immune and nervous systems, and other miscellaneous mechanisms of action. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Jul; 132(3):315-39. PMID: 12161166.
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    104. Hoye TR, Ayyad SE, Eklov BM, Hashish NE, Shier WT, El-Sayed KA, Hamann MT. Toward computing relative configurations: 16-epi-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B. J Am Chem Soc. 2002 Jun 26; 124(25):7405-10. PMID: 12071749.
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    105. Hu JF, Schetz JA, Kelly M, Peng JN, Ang KK, Flotow H, Leong CY, Ng SB, Buss AD, Wilkins SP, Hamann MT. New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. J Nat Prod. 2002 Apr; 65(4):476-80. PMID: 11975483.
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    106. Gochfeld DJ, Hamann MT. Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp. J Nat Prod. 2001 Nov; 64(11):1477-9. PMID: 11720540.
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    107. El Sayed KA, Hamann MT, Hashish NE, Shier WT, Kelly M, Khan AA. Antimalarial, antiviral, and antitoxoplasmosis norsesterterpene peroxide acids from the Red Sea sponge Diacarnus erythraeanus. J Nat Prod. 2001 Apr; 64(4):522-4. PMID: 11325240.
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    108. El Sayed KA, Kelly M, Kara UA, Ang KK, Katsuyama I, Dunbar DC, Khan AA, Hamann MT. New manzamine alkaloids with potent activity against infectious diseases. J Am Chem Soc. 2001 Mar 07; 123(9):1804-8. PMID: 11456797.
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    109. Kouzi SA, Chatterjee P, Pezzuto JM, Hamann MT. Microbial transformations of the antimelanoma agent betulinic acid. J Nat Prod. 2000 Dec; 63(12):1653-7. PMID: 11141108.
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    110. Baser KH, Demirci B, Demirci F, Bedir E, Weyerstahl P, Marschall H, Duman H, Aytaç Z, Hamann MT. A new bisabolene derivative from the essential oil of Prangos uechtritzii fruits. Planta Med. 2000 Oct; 66(7):674-7. PMID: 11105582.
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    111. Chatterjee P, Kouzi SA, Pezzuto JM, Hamann MT. Biotransformation of the antimelanoma agent betulinic acid by Bacillus megaterium ATCC 13368. Appl Environ Microbiol. 2000 Sep; 66(9):3850-5. PMID: 10966400; PMCID: PMC92230.
    112. Demirci B, Baser KH, Demirci F, Hamann MT. New caryophyllene derivatives from Betula litwinowii. J Nat Prod. 2000 Jul; 63(7):902-4. PMID: 10924162.
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    113. Ang KK, Holmes MJ, Higa T, Hamann MT, Kara UA. In vivo antimalarial activity of the beta-carboline alkaloid manzamine A. Antimicrob Agents Chemother. 2000 Jun; 44(6):1645-9. PMID: 10817722; PMCID: PMC89926.
    114. Ross SA, Weete JD, Schinazi RF, Wirtz SS, Tharnish P, Scheuer PJ, Hamann MT. Mololipids, a new series of anti-HIV bromotyramine-derived compounds from a sponge of the order verongida. J Nat Prod. 2000 Apr; 63(4):501-3. PMID: 10785423.
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    115. Cichewicz RH, Kouzi SA, Hamann MT. Dimerization of resveratrol by the grapevine pathogen Botrytis cinerea. J Nat Prod. 2000 Jan; 63(1):29-33. PMID: 10650073.
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    116. Shen X, Krasnoff SB, Lu SW, Dunbar CD, O'Neal J, Turgeon BG, Yoder OC, Gibson DM, Hamann MT. Characterization of 6-epi-3-anhydroophiobolin B from Cochliobolus heterostrophus. J Nat Prod. 1999 Jun; 62(6):895-7. PMID: 10395513.
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    117. Zjawiony JK, Bartyzel P, Hamann MT. Chemistry of puupehenone: 1,6-conjugate addition to its quinone-methide system. J Nat Prod. 1998 Dec; 61(12):1502-8. PMID: 9868151.
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    118. Shen X, Perry TL, Dunbar CD, Kelly-Borges M, Hamann MT. Debromosceptrin, an alkaloid from the Caribbean sponge Agelas conifera. J Nat Prod. 1998 Oct; 61(10):1302-3. PMID: 9784176.
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    119. El Sayed KA, Hamann MT, Abd El-Rahman HA, Zaghloul AM. New pyrrole alkaloids from Solanum sodomaeum. J Nat Prod. 1998 Jun 26; 61(6):848-50. PMID: 9644084.
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    120. Ross SA, el Sayed KA, el Sohly MA, Hamann MT, Abdel-Halim OB, Ahmed AF, Ahmed MM. Phytochemical analysis of Geigeria alata and Francoeuria crispa essential oils. Planta Med. 1997 Oct; 63(5):479-82. PMID: 9342957.
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    121. el Sayed KA, Hamann MT. A new norcembranoid dimer from the red sea soft coral Sinularia gardineri. J Nat Prod. 1996 Jul; 59(7):687-9. PMID: 8759167.
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    122. Wesson KJ, Hamann MT. Keenamide A, a bioactive cyclic peptide from the marine mollusk Pleurobranchus forskalii. J Nat Prod. 1996 Jun; 59(6):629-31. PMID: 8786369.
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    123. Bernheim L, Liu JH, Hamann M, Haenggeli CA, Fischer-Lougheed J, Bader CR. Contribution of a non-inactivating potassium current to the resting membrane potential of fusion-competent human myoblasts. J Physiol. 1996 May 15; 493 ( Pt 1):129-41. PMID: 8735699; PMCID: PMC1158955.
    124. Bernheim L, Hamann M, Liu JH, Fischer-Lougheed J, Bader CR. Role of nicotinic acetylcholine receptors at the vertebrate myotendinous junction: a hypothesis. Neuromuscul Disord. 1996 May; 6(3):211-4. PMID: 8784810.
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    125. Krause RM, Hamann M, Bader CR, Liu JH, Baroffio A, Bernheim L. Activation of nicotinic acetylcholine receptors increases the rate of fusion of cultured human myoblasts. J Physiol. 1995 Dec 15; 489 ( Pt 3):779-90. PMID: 8788942; PMCID: PMC1156847.
    126. Scholz H, Krämer BK, Hamann M, Götz KH, Kurtz A. Effects of endothelins on renin secretion from rat kidneys. Acta Physiol Scand. 1995 Oct; 155(2):173-82. PMID: 8669290.
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    127. McClintock JB, Baker BJ, Hamann MT, Yoshida W, Slattery M, Heine JN, Bryan PJ, Jayatilake GS, Moon BH. Homarine as a feeding deterrent in common shallow-water antarctic lamellarian gastropodMarseniopsis mollis: A rare example of chemical defense in a marine prosobranch. J Chem Ecol. 1994 Oct; 20(10):2539-49. PMID: 24241830.
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    128. Hamann M, Desarmenien M, Desaulles E, Bader MF, Feltz P. Quantitative evaluation of the properties of a pyridazinyl GABA derivative (SR 95531) as a GABAA competitive antagonist. An electrophysiological approach. Brain Res. 1988 Mar 01; 442(2):287-96. PMID: 2453249.
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