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Professor Daniel Goldberg

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Goldberg DE. Plasmepsin V shows its carnivorous side. Nat Struct Mol Biol. 2015 Sep; 22(9):647-8. PMID: 26333709.
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    2. Sigala PA, Crowley JR, Henderson JP, Goldberg DE. Deconvoluting heme biosynthesis to target blood-stage malaria parasites. Elife. 2015 Jul 14; 4. PMID: 26173178.
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    3. Meyers MJ, Anderson EJ, McNitt SA, Krenning TM, Singh M, Xu J, Zeng W, Qin L, Xu W, Zhao S, Qin L, Eickhoff CS, Oliva J, Campbell MA, Arnett SD, Prinsen MJ, Griggs DW, Ruminski PG, Goldberg DE, Ding K, Liu X, Tu Z, Tortorella MD, Sverdrup FM, Chen X. Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents. Bioorg Med Chem. 2015 Aug 15; 23(16):5144-50. PMID: 25797165.
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    4. Mallari JP, Oksman A, Vaupel B, Goldberg DE. Kinase-associated endopeptidase 1 (Kae1) participates in an atypical ribosome-associated complex in the apicoplast of Plasmodium falciparum. J Biol Chem. 2014 Oct 24; 289(43):30025-39. PMID: 25204654.
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    5. Beck JR, Muralidharan V, Oksman A, Goldberg DE. PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes. Nature. 2014 Jul 31; 511(7511):592-5. PMID: 25043010.
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    6. Sigala PA, Goldberg DE. The peculiarities and paradoxes of Plasmodium heme metabolism. Annu Rev Microbiol. 2014; 68:259-78. PMID: 25002093.
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    7. Meyers MJ, Tortorella MD, Xu J, Qin L, He Z, Lang X, Zeng W, Xu W, Qin L, Prinsen MJ, Sverdrup FM, Eickhoff CS, Griggs DW, Oliva J, Ruminski PG, Jacobsen EJ, Campbell MA, Wood DC, Goldberg DE, Liu X, Lu Y, Lu X, Tu Z, Lu X, Ding K, Chen X. Evaluation of aminohydantoins as a novel class of antimalarial agents. ACS Med Chem Lett. 2014 Jan 09; 5(1):89-93. PMID: 24900778.
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    8. Muralidharan V, Goldberg DE. Asparagine repeats in Plasmodium falciparum proteins: good for nothing? PLoS Pathog. 2013; 9(8):e1003488. PMID: 23990777.
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    9. Goldberg DE. Complex nature of malaria parasite hemoglobin degradation [corrected]. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5283-4. PMID: 23513214.
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    10. Goldberg DE. Plasmodium protein export at higher PEXEL resolution. Cell Host Microbe. 2012 Nov 15; 12(5):609-10. PMID: 23159050.
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    11. Babbitt SE, Altenhofen L, Cobbold SA, Istvan ES, Fennell C, Doerig C, Llinás M, Goldberg DE. Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):E3278-87. PMID: 23112171.
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    12. Sigala PA, Crowley JR, Hsieh S, Henderson JP, Goldberg DE. Direct tests of enzymatic heme degradation by the malaria parasite Plasmodium falciparum. J Biol Chem. 2012 Nov 02; 287(45):37793-807. PMID: 22992734.
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    13. Goldberg DE, Siliciano RF, Jacobs WR. Outwitting evolution: fighting drug-resistant TB, malaria, and HIV. Cell. 2012 Mar 16; 148(6):1271-83. PMID: 22424234.
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    14. Meyers MJ, Goldberg DE. Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts. Curr Top Med Chem. 2012; 12(5):445-55. PMID: 22242846.
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    15. Muralidharan V, Oksman A, Pal P, Lindquist S, Goldberg DE. Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers. Nat Commun. 2012; 3:1310. PMID: 23250440.
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    16. Saify ZS, Azim MK, Ahmad W, Nisa M, Goldberg DE, Hussain SA, Akhtar S, Akram A, Arayne A, Oksman A, Khan IA. New benzimidazole derivatives as antiplasmodial agents and plasmepsin inhibitors: synthesis and analysis of structure-activity relationships. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):1282-6. PMID: 22204908.
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    17. Ndonwi M, Burlingame OO, Miller AS, Tollefsen DM, Broze GJ, Goldberg DE. Inhibition of antithrombin by Plasmodium falciparum histidine-rich protein II. Blood. 2011 Jun 09; 117(23):6347-54. PMID: 21511958.
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    18. Muralidharan V, Oksman A, Iwamoto M, Wandless TJ, Goldberg DE. Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag. Proc Natl Acad Sci U S A. 2011 Mar 15; 108(11):4411-6. PMID: 21368162.
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    19. Istvan ES, Dharia NV, Bopp SE, Gluzman I, Winzeler EA, Goldberg DE. Validation of isoleucine utilization targets in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1627-32. PMID: 21205898.
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    20. Goldberg DE, Cowman AF. Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes. Nat Rev Microbiol. 2010 09; 8(9):617-21. PMID: 20706280.
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    21. Goldberg DE, Janse CJ, Cowman AF, Waters AP. Has the time come for us to complement our malaria parasites? Trends Parasitol. 2011 Jan; 27(1):1-2. PMID: 20667784.
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    22. Russo I, Babbitt S, Muralidharan V, Butler T, Oksman A, Goldberg DE. Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte. Nature. 2010 Feb 04; 463(7281):632-6. PMID: 20130644.
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    23. Fennell C, Babbitt S, Russo I, Wilkes J, Ranford-Cartwright L, Goldberg DE, Doerig C. PfeIK1, a eukaryotic initiation factor 2alpha kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation. Malar J. 2009 May 12; 8:99. PMID: 19435497.
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    24. Russo I, Oksman A, Goldberg DE. Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus. Mol Microbiol. 2009 Apr; 72(1):229-45. PMID: 19239622.
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    25. Russo I, Oksman A, Vaupel B, Goldberg DE. A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development. Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1554-9. PMID: 19164769.
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    26. Harpstrite SE, Collins SD, Oksman A, Goldberg DE, Sharma V. Synthesis, characterization, and antimalarial activity of novel schiff-base-phenol and naphthalene-amine ligands. Med Chem. 2008 Jul; 4(4):392-5. PMID: 18673153.
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    27. Lisk G, Pain M, Gluzman IY, Kambhampati S, Furuya T, Su XZ, Fay MP, Goldberg DE, Desai SA. Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes. Antimicrob Agents Chemother. 2008 Jul; 52(7):2346-54. PMID: 18443109.
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    28. Drew ME, Banerjee R, Uffman EW, Gilbertson S, Rosenthal PJ, Goldberg DE. Plasmodium food vacuole plasmepsins are activated by falcipains. J Biol Chem. 2008 May 09; 283(19):12870-6. PMID: 18308731.
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    29. Armstrong CM, Goldberg DE. An FKBP destabilization domain modulates protein levels in Plasmodium falciparum. Nat Methods. 2007 Dec; 4(12):1007-9. PMID: 17994030.
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    30. Ponpuak M, Klemba M, Park M, Gluzman IY, Lamppa GK, Goldberg DE. A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast. Mol Microbiol. 2007 Jan; 63(2):314-34. PMID: 17074076.
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    31. Liu J, Istvan ES, Goldberg DE. Hemoglobin-degrading plasmepsin II is active as a monomer. J Biol Chem. 2006 Dec 15; 281(50):38682-8. PMID: 17040901.
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    32. Parikh S, Liu J, Sijwali P, Gut J, Goldberg DE, Rosenthal PJ. Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin. Antimicrob Agents Chemother. 2006 Jun; 50(6):2207-9. PMID: 16723585.
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    33. Liu J, Istvan ES, Gluzman IY, Gross J, Goldberg DE. Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems. Proc Natl Acad Sci U S A. 2006 Jun 06; 103(23):8840-5. PMID: 16731623.
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    34. Hof F, Schütz A, Fäh C, Meyer S, Bur D, Liu J, Goldberg DE, Diederich F. Starving the malaria parasite: inhibitors active against the aspartic proteases plasmepsins I, II, and IV. Angew Chem Int Ed Engl. 2006 Mar 20; 45(13):2138-41. PMID: 16502446.
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    35. Klemba M, Goldberg DE. Characterization of plasmepsin V, a membrane-bound aspartic protease homolog in the endoplasmic reticulum of Plasmodium falciparum. Mol Biochem Parasitol. 2005 Oct; 143(2):183-91. PMID: 16024107.
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    36. Parikh S, Gut J, Istvan E, Goldberg DE, Havlir DV, Rosenthal PJ. Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors. Antimicrob Agents Chemother. 2005 Jul; 49(7):2983-5. PMID: 15980379.
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    37. Ocheskey JA, Harpstrite SE, Oksman A, Goldberg DE, Sharma V. Metalloantimalarials: synthesis and characterization of a novel agent possessing activity against Plasmodium falciparum. Chem Commun (Camb). 2005 Mar 28; (12):1622-4. PMID: 15770280.
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    38. Goldberg DE. Hemoglobin degradation. Curr Top Microbiol Immunol. 2005; 295:275-91. PMID: 16265895.
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    39. Istvan ES, Goldberg DE. Distal substrate interactions enhance plasmepsin activity. J Biol Chem. 2005 Feb 25; 280(8):6890-6. PMID: 15574427.
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    40. Liu J, Gluzman IY, Drew ME, Goldberg DE. The role of Plasmodium falciparum food vacuole plasmepsins. J Biol Chem. 2005 Jan 14; 280(2):1432-7. PMID: 15513918.
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    41. Sullivan B, Kornfeld SA, Frieden C, Goldberg DE. The Washington University Medical Scientist Training Program. Mo Med. 2004 Sep-Oct; 101(5):491-5. PMID: 15535025.
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    42. Klemba M, Gluzman I, Goldberg DE. A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation. J Biol Chem. 2004 Oct 08; 279(41):43000-7. PMID: 15304495.
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    43. Sijwali PS, Kato K, Seydel KB, Gut J, Lehman J, Klemba M, Goldberg DE, Miller LH, Rosenthal PJ. Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites. Proc Natl Acad Sci U S A. 2004 Jun 08; 101(23):8721-6. PMID: 15166288.
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    44. Klemba M, Beatty W, Gluzman I, Goldberg DE. Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum. J Cell Biol. 2004 Jan 05; 164(1):47-56. PMID: 14709539.
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    45. Nezami A, Kimura T, Hidaka K, Kiso A, Liu J, Kiso Y, Goldberg DE, Freire E. High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor. Biochemistry. 2003 Jul 22; 42(28):8459-64. PMID: 12859191.
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    46. Murata CE, Goldberg DE. Plasmodium falciparum falcilysin: a metalloprotease with dual specificity. J Biol Chem. 2003 Sep 26; 278(39):38022-8. PMID: 12876284.
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    47. Banerjee R, Francis SE, Goldberg DE. Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum. Mol Biochem Parasitol. 2003 Jul; 129(2):157-65. PMID: 12850260.
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    48. Okunade AL, Bikoff RE, Casper SJ, Oksman A, Goldberg DE, Lewis WH. Antiplasmodial activity of extracts and quassinoids isolated from seedlings of Ailanthus altissima (Simaroubaceae). Phytother Res. 2003 Jun; 17(6):675-7. PMID: 12820239.
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    49. Murata CE, Goldberg DE. Plasmodium falciparum falcilysin: an unprocessed food vacuole enzyme. Mol Biochem Parasitol. 2003 Jun; 129(1):123-6. PMID: 12798513.
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    50. Harpstrite SE, Beatty AA, Collins SD, Oksman A, Goldberg DE, Sharma V. Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand. Inorg Chem. 2003 Apr 07; 42(7):2294-300. PMID: 12665363.
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    51. Ocheskey JA, Polyakov VR, Harpstrite SE, Oksman A, Goldberg DE, Piwnica-Worms D, Sharma V. Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains. J Inorg Biochem. 2003 Jan 15; 93(3-4):265-70. PMID: 12576290.
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    52. Brinner KM, Mi Kim J, Habashita H, Gluzman IY, Goldberg DE, Ellman JA. Novel and potent anti-malarial agents. Bioorg Med Chem. 2002 Nov; 10(11):3649-61. PMID: 12213481.
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    53. Siripurkpong P, Yuvaniyama J, Wilairat P, Goldberg DE. Active site contribution to specificity of the aspartic proteases plasmepsins I and II. J Biol Chem. 2002 Oct 25; 277(43):41009-13. PMID: 12189138.
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    54. Choi CY, Schneider EL, Kim JM, Gluzman IY, Goldberg DE, Ellman JA, Marletta MA. Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy. Chem Biol. 2002 Aug; 9(8):881-9. PMID: 12204687.
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    55. Akompong T, Kadekoppala M, Harrison T, Oksman A, Goldberg DE, Fujioka H, Samuel BU, Sullivan D, Haldar K. Trans expression of a Plasmodium falciparum histidine-rich protein II (HRPII) reveals sorting of soluble proteins in the periphery of the host erythrocyte and disrupts transport to the malarial food vacuole. J Biol Chem. 2002 Aug 09; 277(32):28923-33. PMID: 12023959.
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    56. Goldberg DE. Parasitology. When the host is smarter than the parasite. Science. 2002 Apr 19; 296(5567):482-3. PMID: 11964467.
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    57. Banerjee R, Liu J, Beatty W, Pelosof L, Klemba M, Goldberg DE. Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):990-5. PMID: 11782538.
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    58. Klemba M, Goldberg DE. Biological roles of proteases in parasitic protozoa. Annu Rev Biochem. 2002; 71:275-305. PMID: 12045098.
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    59. Coombs GH, Goldberg DE, Klemba M, Berry C, Kay J, Mottram JC. Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets. Trends Parasitol. 2001 Nov; 17(11):532-7. PMID: 11872398.
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    60. Okunade AL, Lewis WH, Elvin-Lewis MP, Casper SJ, Goldberg DE. Cinchonicine-derived alkaloids from the bark of the Peruvian Ladenbergia oblongifolia. Fitoterapia. 2001 Aug; 72(6):717-9. PMID: 11543980.
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    61. Mamoun CB, Goldberg DE. Plasmodium protein phosphatase 2C dephosphorylates translation elongation factor 1beta and inhibits its PKC-mediated nucleotide exchange activity in vitro. Mol Microbiol. 2001 Feb; 39(4):973-81. PMID: 11251817.
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    62. Salmon BL, Oksman A, Goldberg DE. Malaria parasite exit from the host erythrocyte: a two-step process requiring extraerythrocytic proteolysis. Proc Natl Acad Sci U S A. 2001 Jan 02; 98(1):271-6. PMID: 11114161.
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    63. Ben Mamoun C, Gluzman IY, Hott C, MacMillan SK, Amarakone AS, Anderson DL, Carlton JM, Dame JB, Chakrabarti D, Martin RK, Brownstein BH, Goldberg DE. Co-ordinated programme of gene expression during asexual intraerythrocytic development of the human malaria parasite Plasmodium falciparum revealed by microarray analysis. Mol Microbiol. 2001 Jan; 39(1):26-36. PMID: 11123685.
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    64. Mamoun CB, Gluzman IY, Beverley SM, Goldberg DE. Transposition of the Drosophila element mariner within the human malaria parasite Plasmodium falciparum. Mol Biochem Parasitol. 2000 Oct; 110(2):405-7. PMID: 11071293.
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    65. Carter NS, Ben Mamoun C, Liu W, Silva EO, Landfear SM, Goldberg DE, Ullman B. Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum. J Biol Chem. 2000 Apr 07; 275(14):10683-91. PMID: 10744765.
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    66. Eggleson KK, Duffin KL, Goldberg DE. Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum. J Biol Chem. 1999 Nov 05; 274(45):32411-7. PMID: 10542284.
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    67. Minning DM, Gow AJ, Bonaventura J, Braun R, Dewhirst M, Goldberg DE, Stamler JS. Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'. Nature. 1999 Sep 30; 401(6752):497-502. PMID: 10519555.
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    68. Mamoun CB, Truong R, Gluzman I, Akopyants NS, Oksman A, Goldberg DE. Transfer of genes into Plasmodium falciparum by polyamidoamine dendrimers. Mol Biochem Parasitol. 1999 Sep 20; 103(1):117-21. PMID: 10514088.
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    69. Mamoun CB, Gluzman IY, Goyard S, Beverley SM, Goldberg DE. A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8716-20. PMID: 10411941.
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    70. Tyas L, Gluzman I, Moon RP, Rupp K, Westling J, Ridley RG, Kay J, Goldberg DE, Berry C. Naturally-occurring and recombinant forms of the aspartic proteinases plasmepsins I and II from the human malaria parasite Plasmodium falciparum. FEBS Lett. 1999 Jul 09; 454(3):210-4. PMID: 10431809.
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    71. Le Bonniec S, Deregnaucourt C, Redeker V, Banerjee R, Grellier P, Goldberg DE, Schrével J. Plasmepsin II, an acidic hemoglobinase from the Plasmodium falciparum food vacuole, is active at neutral pH on the host erythrocyte membrane skeleton. J Biol Chem. 1999 May 14; 274(20):14218-23. PMID: 10318841.
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    72. Haque TS, Skillman AG, Lee CE, Habashita H, Gluzman IY, Ewing TJ, Goldberg DE, Kuntz ID, Ellman JA. Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II. J Med Chem. 1999 Apr 22; 42(8):1428-40. PMID: 10212129.
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    73. Crawford MJ, Goldberg DE. Regulation of the Salmonella typhimurium flavohemoglobin gene. A new pathway for bacterial gene expression in response to nitric oxide. J Biol Chem. 1998 Dec 18; 273(51):34028-32. PMID: 9852058.
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    74. Minning DM, Goldberg DE. Determinants of Ascaris hemoglobin octamer formation. J Biol Chem. 1998 Dec 04; 273(49):32644-9. PMID: 9830004.
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    75. Sullivan DJ, Matile H, Ridley RG, Goldberg DE. A common mechanism for blockade of heme polymerization by antimalarial quinolines. J Biol Chem. 1998 Nov 20; 273(47):31103-7. PMID: 9813011.
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    76. Carroll CD, Johnson TO, Tao S, Lauri G, Orlowski M, Gluzman IY, Goldberg DE, Dolle RE. Evaluation of a structure-based statine cyclic diamino amide encoded combinatorial library against plasmepsin II and cathepsin D. Bioorg Med Chem Lett. 1998 Nov 17; 8(22):3203-6. PMID: 9873703.
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    77. Shear HL, Grinberg L, Gilman J, Fabry ME, Stamatoyannopoulos G, Goldberg DE, Nagel RL. Transgenic mice expressing human fetal globin are protected from malaria by a novel mechanism. Blood. 1998 Oct 01; 92(7):2520-6. PMID: 9746793.
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    78. Carroll CD, Patel H, Johnson TO, Guo T, Orlowski M, He ZM, Cavallaro CL, Guo J, Oksman A, Gluzman IY, Connelly J, Chelsky D, Goldberg DE, Dolle RE. Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library. Bioorg Med Chem Lett. 1998 Sep 08; 8(17):2315-20. PMID: 9873534.
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    79. Crawford MJ, Goldberg DE. Role for the Salmonella flavohemoglobin in protection from nitric oxide. J Biol Chem. 1998 May 15; 273(20):12543-7. PMID: 9575213.
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    80. Mamoun CB, Sullivan DJ, Banerjee R, Goldberg DE. Identification and characterization of an unusual double serine/threonine protein phosphatase 2C in the malaria parasite Plasmodium falciparum. J Biol Chem. 1998 May 01; 273(18):11241-7. PMID: 9556615.
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    81. Silva AM, Lee AY, Erickson JW, Goldberg DE. Structural analysis of plasmepsin II. A comparison with human aspartic proteases. Adv Exp Med Biol. 1998; 436:363-73. PMID: 9561243.
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    82. Kolakovich KA, Gluzman IY, Duffin KL, Goldberg DE. Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production. Mol Biochem Parasitol. 1997 Aug; 87(2):123-35. PMID: 9247924.
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    83. Francis SE, Banerjee R, Goldberg DE. Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II. J Biol Chem. 1997 Jun 06; 272(23):14961-8. PMID: 9169469.
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    84. Goldberg DE, Sharma V, Oksman A, Gluzman IY, Wellems TE, Piwnica-Worms D. Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes. J Biol Chem. 1997 Mar 07; 272(10):6567-72. PMID: 9045684.
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    85. Truong RM, Francis SE, Chakrabarti D, Goldberg DE. Cloning and characterization of Plasmodium falciparum ADP-ribosylation factor and factor-like genes. Mol Biochem Parasitol. 1997 Feb; 84(2):247-53. PMID: 9084044.
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    86. Francis SE, Sullivan DJ, Goldberg DE. Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu Rev Microbiol. 1997; 51:97-123. PMID: 9343345.
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    87. Francis SE, Gluzman IY, Oksman A, Banerjee D, Goldberg DE. Characterization of native falcipain, an enzyme involved in Plasmodium falciparum hemoglobin degradation. Mol Biochem Parasitol. 1996 Dec 20; 83(2):189-200. PMID: 9027752.
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    88. Sullivan DJ, Ayala YM, Goldberg DE. An unexpected 5' untranslated intron in the P. falciparum genes for histidine-rich proteins II and III. Mol Biochem Parasitol. 1996 Dec 20; 83(2):247-51. PMID: 9027758.
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    89. Sullivan DJ, Gluzman IY, Russell DG, Goldberg DE. On the molecular mechanism of chloroquine's antimalarial action. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11865-70. PMID: 8876229.
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    90. Silva AM, Lee AY, Gulnik SV, Maier P, Collins J, Bhat TN, Collins PJ, Cachau RE, Luker KE, Gluzman IY, Francis SE, Oksman A, Goldberg DE, Erickson JW. Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):10034-9. PMID: 8816746.
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    91. Kloek AP, McCarter JP, Setterquist RA, Schedl T, Goldberg DE. Caenorhabditis globin genes: rapid intronic divergence contrasts with conservation of silent exonic sites. J Mol Evol. 1996 Aug; 43(2):101-8. PMID: 8660434.
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    92. Luker KE, Francis SE, Gluzman IY, Goldberg DE. Kinetic analysis of plasmepsins I and II aspartic proteases of the Plasmodium falciparum digestive vacuole. Mol Biochem Parasitol. 1996 Jul; 79(1):71-8. PMID: 8844673.
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    93. Sullivan DJ, Gluzman IY, Goldberg DE. Plasmodium hemozoin formation mediated by histidine-rich proteins. Science. 1996 Jan 12; 271(5246):219-22. PMID: 8539625.
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    94. Minning DM, Kloek AP, Yang J, Mathews FS, Goldberg DE. Subunit interactions in Ascaris hemoglobin octamer formation. J Biol Chem. 1995 Sep 22; 270(38):22248-53. PMID: 7673204.
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    95. Olliaro PL, Goldberg DE. The plasmodium digestive vacuole: metabolic headquarters and choice drug target. Parasitol Today. 1995 Aug; 11(8):294-7. PMID: 15275326.
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    96. Yang J, Kloek AP, Goldberg DE, Mathews FS. The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity. Proc Natl Acad Sci U S A. 1995 May 09; 92(10):4224-8. PMID: 7753786.
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    97. Cross DT, Moran CJ, Brown AP, Oser AB, Goldberg DE, Diego J, Dacey RG. Endovascular treatment of epistaxis in a patient with tuberculosis and a giant petrous carotid pseudoaneurysm. AJNR Am J Neuroradiol. 1995 May; 16(5):1084-6. PMID: 7639131.
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    98. Crawford MJ, Sherman DR, Goldberg DE. Regulation of Saccharomyces cerevisiae flavohemoglobin gene expression. J Biol Chem. 1995 Mar 24; 270(12):6991-6. PMID: 7896850.
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    99. Goldberg DE. The enigmatic oxygen-avid hemoglobin of Ascaris. Bioessays. 1995 Feb; 17(2):177-82. PMID: 7748168.
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    100. Gluzman IY, Francis SE, Oksman A, Smith CE, Duffin KL, Goldberg DE. Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway. J Clin Invest. 1994 Apr; 93(4):1602-8. PMID: 8163662.
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    101. Kloek AP, Yang J, Mathews FS, Frieden C, Goldberg DE. The tyrosine B10 hydroxyl is crucial for oxygen avidity of Ascaris hemoglobin. J Biol Chem. 1994 Jan 28; 269(4):2377-9. PMID: 8300562.
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    102. Francis SE, Gluzman IY, Oksman A, Knickerbocker A, Mueller R, Bryant ML, Sherman DR, Russell DG, Goldberg DE. Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase. EMBO J. 1994 Jan 15; 13(2):306-17. PMID: 8313875.
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    103. Goldberg DE. Hemoglobin degradation in Plasmodium-infected red blood cells. Semin Cell Biol. 1993 Oct; 4(5):355-61. PMID: 8257787.
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    104. Kloek AP, Yang J, Mathews FS, Goldberg DE. Expression, characterization, and crystallization of oxygen-avid Ascaris hemoglobin domains. J Biol Chem. 1993 Aug 25; 268(24):17669-71. PMID: 8349648.
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    105. Kloek AP, Sherman DR, Goldberg DE. Novel gene structure and evolutionary context of Caenorhabditis elegans globin. Gene. 1993 Jul 30; 129(2):215-21. PMID: 8325507.
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    106. Sherman DR, Guinn B, Perdok MM, Goldberg DE. Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris. Science. 1992 Dec 18; 258(5090):1930-2. PMID: 1470914.
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    107. Sherman DR, Kloek AP, Krishnan BR, Guinn B, Goldberg DE. Ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11696-700. PMID: 1465385.
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    108. Goldberg DE, Slater AF. The pathway of hemoglobin degradation in malaria parasites. Parasitol Today. 1992 Aug; 8(8):280-3. PMID: 15463640.
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    109. Goldberg DE. Plasmodial hemoglobin degradation: an ordered pathway in a specialized organelle. Infect Agents Dis. 1992 Aug; 1(4):207-11. PMID: 1365547.
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    110. Goldberg DE, Slater AF, Beavis R, Chait B, Cerami A, Henderson GB. Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease. J Exp Med. 1991 Apr 01; 173(4):961-9. PMID: 2007860.
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    111. Goldberg DE, Slater AF, Cerami A, Henderson GB. Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle. Proc Natl Acad Sci U S A. 1990 Apr; 87(8):2931-5. PMID: 2183218.
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